Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase: Structure–Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)
2017 ◽
Vol 61
(2)
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pp. 599-618
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Keyword(s):
Keyword(s):
2020 ◽
Vol 11
(4)
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pp. 575-581
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Keyword(s):
Keyword(s):
2002 ◽
Vol 2
(3)
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pp. 131-135
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2003 ◽
Vol 278
(13)
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pp. 11032-11040
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Keyword(s):
2014 ◽
Vol 57
(20)
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pp. 8657-8663
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