Mussel-Inspired, One-Step Thiol Functionalization of Solid Surfaces

The search for optimal conditions for the method of synthesis of copper (II) salts to create a unified one-step method for obtaining salts from natural raw materials was the purpose of this work. During the process of salt production, it is desirable that the product accumulates in the solid phase and is easily separated by phase separation methods. The study of the direct interaction of copper (II) oxide with acids in organic liquid media using a bead mill as a reactor and grinding agent of different nature showed that besides the usual places of localization of product that take place in practice, we can meet unusual places of localization of product, such as the surface of a foreign solid phase in the reactor zone, for example, the surface of the grinding agent, reactor elements, etc. It was found that in some cases, localization on a solid surface could be a favorable localization option in terms of the speed of the process. But it happens not always, because it requires specific methods of separation of film from surface, which can be very expensive. Often, the localization of the product on the solid surfaces is an extremely unfavorable localization option. It was found that different variants of product localization of interaction CuO with acids which were implemented in different proportions, prevented the creation of a unified method for producing salts in such systems

Download Full-text

Construction of Carbohydrate Microarrays by Using One-Step, Direct Immobilizations of Diverse Unmodified Glycans on Solid Surfaces

Bioconjugate Chemistry ◽

10.1021/bc800442z ◽

2009 ◽

Vol 20 (1) ◽

pp. 155-162 ◽

Cited By ~ 66

Author(s):

Sungjin Park ◽

Myung-Ryul Lee ◽

Injae Shin

Keyword(s):

Solid Surfaces ◽

One Step

Download Full-text

Better Understanding of the Polymeric Irradiation Using Physico-Electrochemical Characteristics

10.21203/rs.3.rs-631274/v1 ◽

2021 ◽

Author(s):

Hany Abd El-Raheem ◽

Rabeay Y. A. Hassan ◽

Rehab Khaled ◽

Samaa El-Dek ◽

Ahmed Farghali ◽

...

Keyword(s):

Crosslinking Density ◽

Solid Surfaces ◽

Electrochemical Characteristics ◽

X Ray Diffraction ◽

Scanning Calorimetry ◽

Angle Measurements ◽

Structure Changes ◽

Contact Angle Measurements ◽

One Step ◽

A Chain

Abstract Poly (ester-urethane) urea (PEUU) based on ethanolamine as a chain extender contain hydroxyl and amino groups was chemically synthesized using 1,1'-methylenebis(4-isocyanatobenzene) MDI diisocyanates, and castor oil. One step polymerization procedure has been used to complete the PEUU formation and this polymeric target was irradiated with different doses (100, 250, 400 and 600 kGy) of gamma-rays. A full physico-electrochemical characterization package was performed on the solid surfaces, radiated vs non-irradiated, for the better understanding of the structure changes. To that end, Fourier transform infrared spectroscopy (FTIR), and the morphological features were characterized by the scanning electron microscope (SEM). Thermal stability was investigated using the differential scanning calorimetry (DSC), while the crystallinity and electrochemical properties were explored by the X-ray diﬀraction (XRD), and cyclic voltammetry (CV), respectively. Eventually, swelling, crosslinking density, mechanical strength, water absorption and contact angle measurements were discussed. Ultimately, the crosslinking density was discovered to be irradiated dependent. Worth mentioning here, this kind of study is recommended as a protocol that could be applied on other polymeric targets exposed to electromagnetic radiations.

Download Full-text

One-step methodology for the direct covalent capture of GPCRs from complex matrices onto solid surfaces based on the bioorthogonal reaction between haloalkane dehalogenase and chloroalkanes

Chemical Science ◽

10.1039/c7sc03887a ◽

2018 ◽

Vol 9 (2) ◽

pp. 446-456 ◽

Cited By ~ 12

Author(s):

Kaizhu Zeng ◽

Qian Li ◽

Jing Wang ◽

Guowei Yin ◽

Yajun Zhang ◽

...

Keyword(s):

Solid Surfaces ◽

Haloalkane Dehalogenase ◽

Complex Matrices ◽

Bioorthogonal Reaction ◽

Cell Lysates ◽

One Step

An approach is established for the specific immobilization of GPCRs from cell lysates that circumvents labor intensive purification procedures and minimize loss of activity.

Download Full-text

An Interactive Minicomputer Program for the Indexing and Simulation of Electron Diffraction Patterns

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100092670 ◽

1976 ◽

Vol 34 ◽

pp. 542-543

Author(s):

R.P. Goehner ◽

W.T. Hatfield ◽

Prakash Rao

Keyword(s):

Electron Diffraction ◽

Real Time ◽

Pattern Analysis ◽

Flow Diagram ◽

Hard Copy ◽

Time Analysis ◽

Real Time Analysis ◽

Transmission Electron ◽

One Step ◽

Diffraction Patterns

Computer programs are now available in various laboratories for the indexing and simulation of transmission electron diffraction patterns. Although these programs address themselves to the solution of various aspects of the indexing and simulation process, the ultimate goal is to perform real time diffraction pattern analysis directly off of the imaging screen of the transmission electron microscope. The program to be described in this paper represents one step prior to real time analysis. It involves the combination of two programs, described in an earlier paper(l), into a single program for use on an interactive basis with a minicomputer. In our case, the minicomputer is an INTERDATA 70 equipped with a Tektronix 4010-1 graphical display terminal and hard copy unit.A simplified flow diagram of the combined program, written in Fortran IV, is shown in Figure 1. It consists of two programs INDEX and TEDP which index and simulate electron diffraction patterns respectively. The user has the option of choosing either the indexing or simulating aspects of the combined program.

Download Full-text

Nutrient-regulated gene expression in eukaryotes

Biochemical Society Symposium ◽

10.1042/bss0730085 ◽

2006 ◽

Vol 73 ◽

pp. 85-96 ◽

Cited By ~ 8

Author(s):

Richard J. Reece ◽

Laila Beynon ◽

Stacey Holden ◽

Amanda D. Hughes ◽

Karine Rébora ◽

...

Keyword(s):

Gene Expression ◽

Rna Polymerase ◽

Rna Polymerase Ii ◽

Transcriptional Control ◽

Direct Interaction ◽

Signalling Pathways ◽

A Cell ◽

One Step ◽

Higher Eukaryotes ◽

Regulated Gene Expression

The recognition of changes in environmental conditions, and the ability to adapt to these changes, is essential for the viability of cells. There are numerous well characterized systems by which the presence or absence of an individual metabolite may be recognized by a cell. However, the recognition of a metabolite is just one step in a process that often results in changes in the expression of whole sets of genes required to respond to that metabolite. In higher eukaryotes, the signalling pathway between metabolite recognition and transcriptional control can be complex. Recent evidence from the relatively simple eukaryote yeast suggests that complex signalling pathways may be circumvented through the direct interaction between individual metabolites and regulators of RNA polymerase II-mediated transcription. Biochemical and structural analyses are beginning to unravel these elegant genetic control elements.

Download Full-text