scholarly journals Type III Polyketide Synthase β-Ketoacyl-ACP Starter Unit and Ethylmalonyl-CoA Extender Unit Selectivity Discovered byStreptomyces coelicolorGenome Mining

2006 ◽  
Vol 128 (46) ◽  
pp. 14754-14755 ◽  
Author(s):  
Lijiang Song ◽  
Francisco Barona-Gomez ◽  
Christophe Corre ◽  
Longkuan Xiang ◽  
Daniel W. Udwary ◽  
...  
Keyword(s):  
Polyketide Synthase ◽  
Type Iii Polyketide Synthase ◽  
Type Iii ◽  
Starter Unit ◽  
Extender Unit

scholarly journals Biochemical and Structural Characterization of Germicidin Synthase: Analysis of a Type III Polyketide Synthase That Employs Acyl-ACP as a Starter Unit Donor

2012 ◽  
Vol 134 (17) ◽  
pp. 7359-7366 ◽  
Author(s):  
Joseph A. Chemler ◽  
Tonia J. Buchholz ◽  
Todd W. Geders ◽  
David L. Akey ◽  
Christopher M. Rath ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Polyketide Synthase ◽  
Type Iii Polyketide Synthase ◽  
Type Iii ◽  
Starter Unit

Discovery of anti-infective adipostatins through bioactivity-guided isolation and heterologous expression of a type III polyketide synthase

2021 ◽  
pp. 104925
Author(s):  
Lukuan Hou ◽  
Ying Li ◽  
Qihao Wu ◽  
Miyang Li ◽  
Ethan A. Older ◽  
...  
Keyword(s):  
Heterologous Expression ◽  
Polyketide Synthase ◽  
Type Iii Polyketide Synthase ◽  
Type Iii

scholarly journals A Fine Balancing Act of Type III Polyketide Synthase

2004 ◽  
Vol 11 (9) ◽  
pp. 1177-1178 ◽  
Author(s):  
Shiou-Chuan Tsai
Keyword(s):  
Polyketide Synthase ◽  
Type Iii Polyketide Synthase ◽  
Type Iii

scholarly journals Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid–type III polyketide synthase

2006 ◽  
Vol 2 (9) ◽  
pp. 494-502 ◽  
Author(s):  
Michael B Austin ◽  
Tamao Saito ◽  
Marianne E Bowman ◽  
Stephen Haydock ◽  
Atsushi Kato ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Dictyostelium Discoideum ◽  
Polyketide Synthase ◽  
Type I ◽  
Type Iii Polyketide Synthase ◽  
Type Iii ◽  
Hybrid Type ◽  
Acid Type ◽  
Fatty Acid Type

scholarly journals In silico identification of Capsicum type III polyketide synthase genes and expression patterns in Capsicum annuum

2020 ◽  
Vol 15 (1) ◽  
pp. 753-762
Author(s):  
Delong Kan ◽  
Di Zhao ◽  
Pengfei Duan
Keyword(s):  
Molecular Mechanisms ◽  
Polyketide Synthase ◽  
Expression Patterns ◽  
Class Ii ◽  
Chili Pepper ◽  
Type Iii Polyketide Synthase ◽  
Type Iii ◽  
Genes Encoding ◽  
Duplication Events ◽  
Pepper Leaves

AbstractStudies have shown that abundant and various flavonoids accumulate in chili pepper (Capsicum), but there are few reports on the genes that govern chili pepper flavonoid biosynthesis. Here, we report the comprehensive identification of genes encoding type III polyketide synthase (PKS), an important enzyme catalyzing the generation of flavonoid backbones. In total, 13, 14 and 13 type III PKS genes were identified in each genome of C. annuum, C. chinense and C. baccatum, respectively. The phylogeny topology of Capsicum PKSs is similar to those in other plants, as it showed two classes of genes. Within each class, clades can be further identified. Class II genes likely encode chalcone synthase (CHS) as they are placed together with the Arabidopsis CHS gene, which experienced extensive expansions in the genomes of Capsicum. Interestingly, 8 of the 11 Class II genes form three clusters in the genome of C. annuum, which is likely the result of tandem duplication events. Four genes are not expressed in the tissues of C. annuum, three of which are located in the clusters, indicating that a portion of genes was pseudogenized after tandem duplications. Expression of two Class I genes was complementary to each other, and all the genes in Class II were not expressed in roots of C. annuum. Two Class II genes (CA00g90790 and CA05g17060) showed upregulated expression as the chili pepper leaves matured, and two Class II genes (CA05g17060 and CA12g20070) showed downregulated expression with the maturation of fruits, consistent with flavonoid accumulation trends in chili pepper as reported previously. The identified genes, sequences, phylogeny and expression information collected in this article lay the groundwork for future studies on the molecular mechanisms of chili pepper flavonoid metabolism.

Identification of a Polygonum cuspidatum three-intron gene encoding a type III polyketide synthase producing both naringenin and p-hydroxybenzalacetone

Planta ◽  
2009 ◽  
Vol 229 (5) ◽  
pp. 1077-1086 ◽  
Author(s):  
Lan-Qing Ma ◽  
Yan-Wu Guo ◽  
Dong-Yao Gao ◽  
Dong-Ming Ma ◽  
You-Nian Wang ◽  
...  
Keyword(s):  
Polyketide Synthase ◽  
Polygonum Cuspidatum ◽  
Gene Encoding ◽  
Type Iii Polyketide Synthase ◽  
Type Iii

PpORS, an ancient type III polyketide synthase, is required for integrity of leaf cuticle and resistance to dehydration in the moss, Physcomitrella patens

Planta ◽  
2017 ◽  
Vol 247 (2) ◽  
pp. 527-541 ◽  
Author(s):  
Li Li ◽  
Misbah Aslam ◽  
Fazle Rabbi ◽  
Mark C. Vanderwel ◽  
Neil W. Ashton ◽  
...  
Keyword(s):  
Polyketide Synthase ◽  
Physcomitrella Patens ◽  
Type Iii Polyketide Synthase ◽  
Type Iii ◽  
Leaf Cuticle

scholarly journals Expression, purification and crystallization of a plant type III polyketide synthase that produces diarylheptanoids

2010 ◽  
Vol 66 (8) ◽  
pp. 948-950 ◽  
Author(s):  
Hiroyuki Morita ◽  
Kiyofumi Wanibuchi ◽  
Ryohei Kato ◽  
Shigetoshi Sugio ◽  
Ikuro Abe
Keyword(s):  
Polyketide Synthase ◽  
Plant Type ◽  
Type Iii Polyketide Synthase ◽  
Type Iii

Fatty Acyl-AMP Ligase Involvement in the Production of Alkylresorcylic Acid by a Myxococcus xanthus Type III Polyketide Synthase

ChemBioChem ◽  
2011 ◽  
Vol 12 (14) ◽  
pp. 2166-2176 ◽  
Author(s):  
Takayuki Hayashi ◽  
Yuta Kitamura ◽  
Nobutaka Funa ◽  
Yasuo Ohnishi ◽  
Sueharu Horinouchi
Keyword(s):  
Polyketide Synthase ◽  
Myxococcus Xanthus ◽  
Fatty Acyl ◽  
Type Iii Polyketide Synthase ◽  
Type Iii
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