In Vitro Antioxidative Effects and Tyrosinase Inhibitory Activities of Seven Hydroxycinnamoyl Derivatives in Green Coffee Beans

2004 ◽  
Vol 52 (15) ◽  
pp. 4893-4898 ◽  
Author(s):  
Kazuya Iwai ◽  
Noriaki Kishimoto ◽  
Yukari Kakino ◽  
Kyo Mochida ◽  
Tokio Fujita
2022 ◽  
pp. 101552
Author(s):  
Ammar Mohammed Ahmed Ali ◽  
Sakina Yagi ◽  
Ahmed A. Qahtan ◽  
Abdurrahman A. Alatar ◽  
Simone Angeloni ◽  
...  

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
U Gawlik-Dziki ◽  
M Świeca ◽  
Ł Pecio ◽  
D Dziki

2019 ◽  
Vol 7 (3) ◽  
pp. 1084-1095 ◽  
Author(s):  
Ke Cheng ◽  
Wenjiang Dong ◽  
Yuzhou Long ◽  
Jianping Zhao ◽  
Rongsuo Hu ◽  
...  

2020 ◽  
pp. 24-35
Author(s):  
Dileep Polamuri ◽  
CH. Grace Valentina ◽  
R. Suresh ◽  
Aminul Islam

The main objective of this article is to analyze the efficacy of polyphonic compounds, especially Chlorogenic Acid in anti-obesity and anticancer. Overweight and obesity became severe global health issues in all sex and age groups respectively according to WHO, this is the significant risk factors for several chronic illnesses this is increasing from recent decades, due to lifestyle changes intake of food lack of proper healthcare particularly in urban communities. According to the India Council of Medical Research (ICMR), more than 1300 Indians die every day due to cancer, especially Basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and malignant melanoma are primary skin cancers. This research aims to help anti-obese and anticancer by providing health benefits of green Coffee. The ethnobotanical study proved that green coffee beans of Coffee Robusta variety have significant medicinal properties, which are essential for the human diet. In vitro results showed that high free radical scavenging activity with IC50 towards DPPH 30.99µg/mL ABTS0.83 µg/mL, Alpha-amylase 31.75 µg/mL, MTT assay 101.26 µg/mL and Anti-obesity activity 33.34 µg/mL respectively. In conclusion, more in vivo and in vitro experimental studies are required to understand the full use of the extract in the prevention of lethal diseases.


2017 ◽  
Vol 128 ◽  
pp. 386-394 ◽  
Author(s):  
Heber P. Cornelio-Santiago ◽  
Cintia Bernardo Gonçalves ◽  
Naila Albertina de Oliveira ◽  
Alessandra Lopes de Oliveira

2021 ◽  
pp. 130504
Author(s):  
Fareeya Kulapichitr ◽  
Chaleeda Borompichaichartkul ◽  
Mingchih Fang ◽  
Inthawoot Suppavorasatit ◽  
Keith R. Cadwallader

Food Control ◽  
2019 ◽  
Vol 99 ◽  
pp. 137-145 ◽  
Author(s):  
A. Giraudo ◽  
S. Grassi ◽  
F. Savorani ◽  
G. Gavoci ◽  
E. Casiraghi ◽  
...  

1986 ◽  
Vol 25 (6) ◽  
pp. 1496-1497 ◽  
Author(s):  
Hideko Morishita ◽  
Hideo Iwahashi ◽  
Ryo Kido

2008 ◽  
Vol 9 (4) ◽  
pp. 534-541 ◽  
Author(s):  
Ibtisam M. Kamal ◽  
V. Sobolik ◽  
Magdalena Kristiawan ◽  
Sabah M. Mounir ◽  
K. Allaf

2021 ◽  
Vol 22 (1) ◽  
pp. 133-140
Author(s):  
Farra Sasmita ◽  
Ietje Wientarsih ◽  
Bayu Febram Prasetyo ◽  
Bambang Pontjo Priosoeryanto

This study aim at determining the activity of ethanol extract of Robusta green coffee beans as an antiproliferation agent in MCA-B1, MCM-B2, and Vero normal cell lines as a control. Ethanol extract of Robusta green coffee beans was obtained by maceration method, bioactive compounds in the extract were tested by phytochemical screening methods, testing levels of antioxidants were tested by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, cytotoxicity effects (LC50) were tested by the method Brine Shrimp Lethallity Test (BSLT) and antiproliferation activity were carried out by counting the number of cells after being tested with several extract concentrations namely 100, 250, 400, 550, 700 and 850 ppm and doxorubicin as a positive control with a concentration of 100 ppm. The results showed that the ethanol extract of Robusta green coffee beans contained flavonoids and tannins, had very strong antioxidant levels with IC50 values of 40.9923 ppm, cytotoxicity effects obtained LC50 values of 430.64 ppm, and the highest antiproliferation activity was achieved at a concentration of 850 ppm at 69.58 % in MCM-B2 tumor cells, 60.46% in MCA-B1 tumor cells, and 14.2% in Vero normal cells. Based on the results, the ethanol extract of Robusta Lampung green coffee beans has antiproliferation activity on the test tumor cells and is relatively non-toxic to normal cells.


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