In this chapter, the authors present a methodology for simulating human navigation within the context of public, multi-modal transport. They show that cognitive agents, that is, agents that can reason about the navigation process and learn from and navigate through the (simulated physical) environment, require the provision of a rich spatial environment. From a cognitive standpoint, human navigation and wayfinding rely on a combination of spatial models (“knowledge in the head”), (default) reasoning processes, and knowledge in the world. Spatial models have been studied extensively, whereas the reasoning processes and especially the role of the “knowledge in the world” have been neglected. The authors first present an overview of research in wayfinding and then envision a model that integrates existing concepts and models for multi-modal public transport illustrated by a case study.