Outcomes of combined treatment: Evaluating split versus integrated treatment for depression.

2017 ◽  
Vol 48 (5) ◽  
pp. 361-368 ◽  
Author(s):  
Rachel Levine Baruch ◽  
Rachel A. Annunziato
Keyword(s):  
Combined Treatment ◽  
Integrated Treatment

Neoadjuvant Chemotherapy to Radiation and Concurrent Chemoradiation for Locally Advanced Squamous Cell Carcinoma of the Cervix: A Review of the Recent Literature

1998 ◽  
Vol 84 (2) ◽  
pp. 229-237 ◽  
Author(s):  
Alessandro Colombo ◽  
Fabio Landoni ◽  
Andrea Maneo ◽  
Gerardo Zanetta ◽  
Simonetta Nava ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Local Control ◽  
Randomized Trials ◽  
Recent Literature ◽  
Combined Treatment ◽  
Locally Advanced ◽  
Distant Metastases ◽  
Integrated Treatment ◽  
Concurrent Chemoradiation ◽  
Late Morbidity

Radiotherapy is the standard treatment for locally advanced cervical cancer; nevertheless it fails to control disease progression within the irradiation fields in more than 40% of cases, particularly in patients with bulky tumor. Distant metastases are not infrequent in more advanced cases. Chemotherapy has been integrated with radiotherapy to improve local control and treat distant subclinical metastases. Schedules of combined treatment more frequently represented by neoadjuvant chemotherapy followed by radiation (NACT) and by concomitant chemotherapy and radiation (CT-RT). A review of the recent literature is presented. The role of NACT is controversial: high response rates are reported but doubtful advantages in terms of survival or local control have been shown. In randomized trials, hydroxyurea concomitant to radiation improves local control and survival, particularly in stage IIIB and IVA. Several randomized trials of concurrent chemoradiation with 5FU, cisplatin and mitomycin C are underway, but few have been published: no significative differences are reported in term of local control or survival. Acute toxicity is higher than in radiation alone, but usually manageable. For the analysis of late morbidity a longer follow-up is required. Large randomized trials of adequate radiotherapy versus concomitant chemoradiation are necessary to refine our understanding of the benefits of this integrated treatment.

scholarly journals Performance of a Combined Treatment Approach on Elimination of Microbes from Poultry Slaughterhouse Wastewater

2021 ◽  
Author(s):  
Kulyash Meiramkulova ◽  
Aliya Теmirbekova ◽  
Gulnur Saspugayeva ◽  
Assel Kydyrbekova ◽  
Davud Devrishov ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Removal Efficiency ◽  
Combined Treatment ◽  
Treatment Plant ◽  
Integrated Treatment ◽  
Microbial Inactivation ◽  
Treated Wastewater ◽  
Coliform Bacteria ◽  
Treatment Unit ◽  
Slaughterhouse Wastewater

The efficiency of microbial inactivation in water is highly dependent on the type of treatment technology used as well as the characteristics of the water to be treated. Wastewater from poultry slaughterhouses carries a significant number of microorganisms posing threat to humans and the environment in general. Therefore, the treatment of poultry slaughterhouse wastewater requires the use of appropriate purification systems with high removal efficiency for microbial agents. In this study, the performance of an integrated treatment plant with electrolysis, ultrafiltration, and ultraviolet radiation as the principal treatment units is investigated in terms of microbial inactivation from poultry slaughterhouse wastewater. In this case, Total microbial number, Total coliform bacteria, Thermo-tolerant coliform bacteria, Pathogenic flora, including Salmonella coliphages, Spores of sulfite-reducing clostridia, Pseudomonas aeruginosa, and Staphylococcus aureus Enterococcus were studied. About 63.95% to 99.83% of the microbes were removed by the EC treatment unit, as well as 99.86% to 100% removal efficiency was achieved after the combined treatment. However, the Pseudomonas aeruginosa was the only microbial agent detected in the final effluent after the combined treatment. The phenomenon suggests that an upgrade to the treatment plant may be required to achieve 100% removal assurance for Pseudomonas aeruginosa.

scholarly journals An evaluation of combined narrative exposure therapy and physiotherapy for comorbid PTSD and chronic pain in torture survivors

2017 ◽  
Vol 27 (1) ◽  
Author(s):  
Iselin Dibaj ◽  
Joar Øveraas Halvorsen ◽  
Leif Edward Ottesen Kennair ◽  
Håkon Inge Stenmark
Keyword(s):  
Chronic Pain ◽  
Pain Intensity ◽  
Exposure Therapy ◽  
Combined Treatment ◽  
Case Series ◽  
Integrated Treatment ◽  
Valuable Insight ◽  
Torture Survivors ◽  
Narrative Exposure Therapy ◽  
Clinically Significant

Abstract Introduction: Torture is associated with adverse health consequences, with especially high rates of PTSD, depression and chronic pain. Despite increased awareness of the relationship between pain and posttraumatic symptoms, and the accompanying need for effective treatment strategies, few studies have examined an integrated treatment of comorbid PTSD and pain. Methods: In this study, using an A-B case series design with three and six month follow-up, six refugee torture survivors with comorbid PTSD, depression and chronic pain received 20 sessions of Narrative Exposure Therapy (NET) and 10 sessions of physiotherapy. Outcome variables included symptoms of PTSD and depression, pain intensity, physical functioning and quality of life. Symptoms of PTSD and pain were also rated after each treatment session. Results: Two patients achieved clinically significant reduction in symptoms of PTSD. Only one patient achieved clinically significant change in depressive symptoms, and two experienced clinically significant reduction in pain intensity. Clinical descriptions of the course of treatment for all patients are provided. Discussion and Conclusions: Despite its limitations, the study suggests that some torture survivors who suffer high symptom loads may benefit from a combined treatment of NET and physiotherapy. Appreciating individual differences and how they affect treatment can provide valuable insight and inform clinicians working with torture survivors. Directions for future research regarding the improvement of rehabilitation strategies of torture survivors are discussed, and highlighted through descriptions from the six therapy cases.

scholarly journals Allelopathy Weed management and yield improvement in mungbean through allelopathic action of sunflower and bermuda grass (a weed) extract in conjunction with irrigation frequencies

2021 ◽  
Vol 27 (3) ◽  
pp. 307-320
Author(s):  
Muhammad Naeem Korejo ◽  
Muhammad Nawaz Kandhro ◽  
Aijaz Ahmed Soomro ◽  
Niaz Ahmed Wahocho
Keyword(s):  
Seed Yield ◽  
Plant Extracts ◽  
Crop Production ◽  
Combined Treatment ◽  
Integrated Treatment ◽  
Bermuda Grass ◽  
Allelopathic Potential ◽  
Weed Density ◽  
Hand Weeding ◽  
Different Levels

Allelopathy is the effect of one plant species by reducing the germination and growth of the neighbouring plants of another species through releasing chemical compounds. It has been reported by many researchers that weeds are major hazard in reducing crop yield but it can be managed effectively through phytotoxic properties of plants. A field study was conducted at Students Experimental Farm, Agronomy Department, Crop Production Faculty, Sindh Agriculture University Tandojam, Pakistan during spring 2019 and repeated during 2020 to validate the previous results. The research conducted to evaluate the allelopathic potential of sunflower and Bermuda grass extracts under various irrigation levels on weeds density and yield of mungbean cultivar ‘AEM-96’. Split plot design having four replications was managed. The experiment consisted of weed control practices: Weedy check, various levels of sunflower and bermuda grass extracts as sole and in combination with each other, different levels of herbicides as alone and in integration with allelopathic plant extracts as well as hand weeding under three irrigation frequencies (2, 3 and 4 watering applications). The analysis variance of results showed that various levels of sunflower and bermuda grass extracts as sole and in combination with each other, different levels of herbicides as alone and in integration with allelopathic plant extracts as well as hand weeding caused significant suppression of weeds and increased in seed yield as compared to weedy check. The combined treatment Atlantis: 0.1 Ltr ha-1 + Puma Super: 0.156 Ltr ha-1 + Sunflower extract: 15 L ha-1 resulted in less weed density (51.6 m-2) and produced maximum seed yield of 2404.4 kgs ha-1. Bermuda grass extract: 15 Ltr ha-1 integration with low dose of herbicides Atlantis: 0.1 Ltr ha-1+ Puma Super: 0.156 Ltr ha-1 showed weed density of 61.3 m-2 resulted seed yield of 2282.1 kgs ha-1. The application of herbicides treatment Atlantis: 0.2 Ltr ha-1 + Puma Super: 0.312 Ltr ha-1 suppressed weed density of 70.9 m-2 and produced seed yield of 2162.5 kgs ha-1. It is noted that Hand weeding: 30 days after sowing showed weed density of 76.1 m-2 and seed yield 2042.5 kgs ha-1. The combined allelopathic plant applications of Sunflower +Bermuda grass extract each: 15 Ltr ha-1 reduced weed density 80.7 m-2 and obtained seed yield of 1923.2 kgs ha-1. Sole application of sunflower extract: 30 Ltr ha-1 resulted weed density 91.0 m-2 and recorded seed yield of 1804.2 kgs ha-1. Alone allelopathy application of Bermuda grass extract: 30 Ltr ha-1 noticed weed density 103.3 m-2 and produced seed yield of 1684.8 kgs ha-1. The highest weed density 140.9 m-2 and lowest seed yield 1343.1 kgs ha-1 noticed in weedy check treatment where no any application applied for weed reduction. According to irrigation frequencies the 4 watering applications resulted less weed density 82.2 m-2 and obtained maximum seed yield 1996.3 kgs ha-1 followed by 3 watering applications noted weed density 84.5 m-2 and achieved seed yield 1955.5 kgs ha-1. The maximum weed density 86.7 m-2 and lowest seed yield recorded in 2 watering application. The analysis of variance of pooled data revealed that Atlantis: 0.1 Ltr ha-1 + Puma Super: 0.156 Ltr ha-1 + Sunflower extract: 15 Ltr ha-1 integrated treatment under 4 watering applications (15, 30, 45 and 60 DAS) caused significant impact on weed inhabitation and yield enrichment

scholarly journals Performance of a Combined Treatment Approach on Elimination of Microbes from Poultry Slaughterhouse Wastewater

2021 ◽  
Author(s):  
Kulyash Meiramkulova ◽  
Aliya Теmirbekova ◽  
Gulnur Saspugayeva ◽  
Assel Kydyrbekova ◽  
Davud Devrishov ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Removal Efficiency ◽  
Combined Treatment ◽  
Treatment Plant ◽  
Integrated Treatment ◽  
Microbial Inactivation ◽  
Treated Wastewater ◽  
Coliform Bacteria ◽  
Treatment Unit ◽  
Slaughterhouse Wastewater

The efficiency of microbial inactivation in water is highly dependent on the type of treatment technology used as well as the characteristics of the water to be treated. Wastewater from poultry slaughterhouses carries a significant number of microorganisms posing threat to humans and the environment in general. Therefore, the treatment of poultry slaughterhouse wastewater requires the use of appropriate purification systems with high removal efficiency for microbial agents. In this study, the performance of an integrated treatment plant with electrolysis, ultrafiltration, and ultraviolet radiation as the principal treatment units is investigated in terms of microbial inactivation from poultry slaughterhouse wastewater. In this case, Total microbial number, Total coliform bacteria, Thermo-tolerant coliform bacteria, Pathogenic flora, including Salmonella coliphages, Spores of sulfite-reducing clostridia, Pseudomonas aeruginosa, and Staphylococcus aureus Enterococcus were studied. About 63.95% to 99.83% of the microbes were removed by the EC treatment unit, as well as 99.86% to 100% removal efficiency was achieved after the combined treatment. However, the Pseudomonas aeruginosa was the only microbial agent detected in the final effluent after the combined treatment. The phenomenon suggests that an upgrade to the treatment plant may be required to achieve 100% removal assurance for Pseudomonas aeruginosa.

scholarly journals Performance of a Combined Treatment Approach on the Elimination of Microbes from Poultry Slaughterhouse Wastewater

2021 ◽  
Vol 13 (6) ◽  
pp. 3467
Author(s):  
Kulyash Meiramkulova ◽  
Aliya Temirbekova ◽  
Gulnur Saspugayeva ◽  
Assel Kydyrbekova ◽  
Davud Devrishov ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Removal Efficiency ◽  
Combined Treatment ◽  
Treatment Plant ◽  
Integrated Treatment ◽  
Microbial Inactivation ◽  
Treated Wastewater ◽  
Coliform Bacteria ◽  
Treatment Unit ◽  
Slaughterhouse Wastewater

The efficiency of microbial inactivation in water is highly dependent on the type of treatment technology used as well as the characteristics of the water to be treated. Wastewater from poultry slaughterhouses carries a significant number of microorganisms posing threats to humans and the environment in general. Therefore, the treatment of poultry slaughterhouse wastewater requires the use of appropriate purification systems with high removal efficiency for microbial agents. In this study, the performance of an integrated treatment plant with electrolysis, ultrafiltration, and ultraviolet radiation as the principal treatment units was investigated in terms of microbial inactivation from poultry slaughterhouse wastewater. In this case, total microbial number, total coliform bacteria, thermo-tolerant coliform bacteria, pathogenic flora, including salmonella coliphages, spores of sulfite-reducing clostridia, Pseudomonas aeruginosa, and Staphylococcus aureus and Enterococcus were studied. Approximately 63.95% to 99.83% of the microbes were removed by the electrochemical treatment unit as well as a 99.86% to 100% removal efficiency was achieved after the combined treatment. However, Pseudomonas aeruginosa was the only microbial agent detected in the final effluent after the combined treatment. The phenomenon suggests that an upgrade to the treatment plant may be required to achieve 100% removal assurance for Pseudomonas aeruginosa.

Hybrid treatment of multilevel revascularization in patients with peripheral arterial disease – a multi-centre study in Korea

VASA ◽  
2018 ◽  
Vol 47 (3) ◽  
pp. 235-241 ◽  
Author(s):  
Soon Cheon Lee ◽  
Jin Hyun Joh ◽  
Jeong-Hwan Chang ◽  
Hyung-Kee Kim ◽  
Jang Yong Kim ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Combined Treatment ◽  
Ankle Brachial Index ◽  
Primary Patency ◽  
Limb Ischaemia ◽  
University Hospitals ◽  
Multi Centre Study ◽  
Free Survival ◽  
Technical Success Rate ◽  
Hybrid Treatment

Abstract. Background: Endovascular treatment is an alternative first-line management for peripheral artery disease (PAD). Hybrid treatment (HT) is defined as a combined treatment for patients with PAD using endovascular and open surgery, simultaneously performed in an operating room. The results of HT are reportedly good for multilevel revascularization (MR) in patients with chronic limb ischaemia, and even in older high-risk patients. The goal of this study was to examine the clinical and haemodynamic outcomes of HT in patients who need MR. Patients and methods: Nine university hospitals in Korea participated in this multicentre study. A total of 134 patients with multilevel PAD underwent HT and MR. Patients were enrolled from July 2014 to June 2015 and were followed for 18 months. Results: The mean age of the patients was 68.8 ± 9.93 years and 88.1 % were men. Patients with Rutherford category 2 to 3 and 4 to 6 comprised 59.0 % and 42.0 % of the group, respectively. The technical success rate was 100 %. The primary patency rates at 12 and 18 months were 77.6 % and 63.9 %, respectively. The primary-assisted patency rates at 12 and 18 months were both 90.0 %. The pre-operative mean ankle brachial index (0.43 ± 0.23) increased to 0.87 ± 0.23 at six months post-operatively (t-test, p < 0.05). The amputation free survival rate was 97.1 %. Conclusions: Although outcomes of multilevel PAD are reportedly poor when endovascular treatment alone is used, we have shown that HT is a feasible alternative modality for patients with multilevel PAD, with satisfactory amputation-free survival and freedom from re-intervention rates.

A Case of Catatonia in a 14-Year-Old Girl with Schizophrenia Treated with Electroconvulsive Therapy

2013 ◽  
Vol 41 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Frank Häßler ◽  
Olaf Reis ◽  
Steffen Weirich ◽  
Jacqueline Höppner ◽  
Birgit Pohl ◽  
...  
Keyword(s):  
Case Report ◽  
Treatment Response ◽  
Electroconvulsive Therapy ◽  
Rating Scale ◽  
Combined Treatment ◽  
Adolescent Patient

This article presents a case of a 14-year-old female twin with schizophrenia who developed severe catatonia following treatment with olanzapine. Under a combined treatment with amantadine, electroconvulsive therapy (ECT), and (currently) ziprasidone alone she improved markedly. Severity and course of catatonia including treatment response were evaluated with the Bush-Francis Catatonia Rating Scale (BFCRS). This case report emphasizes the benefit of ECT in the treatment of catatonic symptoms in an adolescent patient with schizophrenic illness.

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