scholarly journals Erratum: Hypertension is an important risk determinant for chronic kidney disease: results from a cross-sectional, observational study from a rural population in South India

2017 ◽  
Vol 31 (5) ◽  
pp. 369-370 ◽  
Author(s):  
Y J Anupama ◽  
S N Hegde ◽  
G Uma ◽  
M Patil
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Observational Study ◽  
Rural Population ◽  
South India ◽  
Cross Sectional

scholarly journals Hubungan Kadar Kreatinin Serum Dengan Kadar Mineral Pada Pasien Chronic Kidney Disease

2020 ◽  
Vol 7 (2) ◽  
pp. 393-397
Author(s):  
Diah Ayu Kusuma ◽  
Indranila Kustarini Samsuria
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Observational Study ◽  
Serum Creatinine ◽  
Kidney Function ◽  
Medical Records ◽  
Retrospective Observational Study ◽  
Metabolic Processes ◽  
Cross Sectional ◽  
Positive Correlation

Pendahuluan : Chronic Kidney Disease (CKD) merupakan gangguan fungsi ginjal yang irreversible, yaitu kemampuan tubuh gagal untuk mempertahankan metabolisme dan keseimbangan cairan dan elektrolit dan juga mineral. Sebagian besar proses metabolisme memerlukan dan dipengaruhi oleh elektrolit. Konsentrasi elektrolit mineral yang tidak normal dapat menyebabkan banyak gangguan .  Saat fungsi ginjal semakin memburuk menjadi Stadium CKD 4 dan 5, ekskresinya cenderung berkurang dan tidak dapat dikompensasi. Tujuan penelitian ini adalah melihat pengaruh CKD pada mineral yaitu magnesium dan calcium. Metode : Penelitian ini adalah penelitian observasional retrospektif dengan pendekatan belah lintang (cross sectional) dengan melihat rekam medik pada senter tunggal di RSUP Dr. Kariadi Semarang selama periode 1 Januari 2017 – 31 Desember 2018 untuk kemudian dilihat hubungan pengaruh kadar kreatinin serum dengan magnesium dan calcium pada pasien CKD dengan terapi hemodialisis. Hasil dan pembahasan: Terdapat hubungan signifikan positif lemah antara kreatinin serum dengan magnesium (p=0,032, r= 0,327).  Tidak terdapat hubungan antara kreatinin serum dengan kadar kalsium. Simpulan : Dari hasil penelitian dapat disimpulkan bahwa secara statistik terdapat hubungan yang bermakna antara kadar kreatinin serum dengan magnesium pada pasien Chronic Kidney Disease (CKD) dengan terapi hemodialisis. Kata Kunci Kreatinin, mineral, magnesium Chronic Kidney Disease, hemodialisis.   ABSTRACT Introduction: Chronic Kidney Disease (CKD) is an irreversible kidney function disorder, which is the body's ability to fail to maintain metabolism and balance fluid and electrolytes and minerals. Most metabolic processes require and are influenced by electrolytes. Abnormal mineral electrolyte concentrations can cause many disturbances. When kidney function getting worse to stages CKD 4 and 5, the excretion tends to decrease and cannot be compensated. The purpose of this study is to look at the effect of CKD on minerals namely magnesium and calcium. Method: This study was a retrospective observational study with a cross sectional approach by looking at medical records at RSUP Dr. Kariadi Semarang during the period of 1 January 2017 - 31 December 2018 to see the correlation of  influence of serum creatinine levels with magnesium and calcium in CKD patients with hemodialysis therapy. Results and discussion: There was a significantly weak positive correlation between serum creatinine and magnesium (p = 0.032, r = 0.327). There is no correlation between serum creatinine and calcium levels. Conclusion: The results of the study it can be concluded that there is a statistically significant correlation between serum creatinine levels with magnesium in Chronic Kidney Disease (CKD) patients with hemodialysis therapy. Keywords Creatinine, minerals, magnesium Chronic Kidney Disease, hemodialysis.

Cardiac Abnormalities in Children with Pre-Dialysis Chronic Kidney Disease in a Resource-Limited Setting: A Cross-Sectional Observational Study

2021 ◽  
Vol 67 (4) ◽  
Author(s):  
Naveen Bhagat ◽  
Lesa Dawman ◽  
Sanjeev Naganur ◽  
Karalanglin Tiewsoh ◽  
Basant Kumar ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Observational Study ◽  
Diastolic Dysfunction ◽  
Serum Calcium ◽  
Systolic Dysfunction ◽  
Left Ventricular ◽  
Cross Sectional ◽  
Cardiac Abnormalities ◽  
Lv Diastolic Dysfunction

Abstract Background Cardiovascular disease is the leading cause of morbidity and mortality in children with chronic kidney disease (CKD). We aim to estimate the prevalence of cardiac abnormalities in children up to age 16 years with CKD and their association with various risk factors. Methods This cross-sectional observational study was conducted on 107 CKD children. We assessed the systolic and diastolic function using 2D echocardiographic evaluation and M-mode measurements of the left ventricle (LV) indexed for BSA and z-scores were calculated. Results were compared with age, sex, stage of CKD, anaemia, estimated glomerular filtration rate (eGFR) and various laboratory parameters. Results LV diastolic dysfunction was seen in 88%, followed by increased LV dimensions in 33.6%, LV systolic dysfunction in 16%, right ventricle systolic dysfunction in 11.2% while increased pulmonary artery (PA) systolic pressure was seen in 9.3% of cases. LV dimensions correlated directly with parathormone levels and inversely with eGFR, serum calcium and haemoglobin levels. Left ventricular hypertrophy correlated directly with parathormone while inversely with eGFR, serum calcium and haemoglobin. Ejection fraction directly correlated to eGFR and serum calcium while inversely related to parathormone. Left PA pressure directly correlated with age and inversely with eGFR. Right ventricular systolic function assessed by tricuspid annular plane systolic excursion correlated inversely with haemoglobin. Conclusion LV diastolic dysfunction and increased LV dimensions were the most common cardiac abnormality in children with CKD. LV dimensions correlated directly with parathormone levels and inversely with eGFR, serum calcium and haemoglobin. Diastolic dysfunction positively correlated with serum creatinine and parathormone levels.

scholarly journals Prevalence of Chronic Kidney Disease (CKD) and Identification of Associated Risk Factors among Rural Population by Mass Screening

2013 ◽  
Vol 1 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Mahmud Javed Hasan ◽  
M Abul Kashem ◽  
M Hasibur Rahman ◽  
Ruhul Qudduhush ◽  
Masudur Rahman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Serum Creatinine ◽  
Rural Population ◽  
Smoking Habit ◽  
Population Based ◽  
Clinical Variable ◽  
Cross Sectional ◽  
Associated Risk Factors

The prevalence of Chronic Kidney Disease (CKD) is rapidly increasing worldwide. Population-based studies on the prevalence of kidney damage are limited in developing countries. The present work relates to a population-based screening study in a rural population. Objectives: The study was performed to investigate the prevalence of chronic kidney disease (CKD) in rural residents and find out the association of the associated risk factors and variables. Methods: This is a descriptive cross sectional study. The demographic variables included were age, sex, marital status, religion, occupation, socioeconomic status, monthly income. The clinical variable was hypertension. The risk factors under the study were Body Mass Index (BMI), smoking habit, hypertension, and diabetes mellitus. Data pertaining to biochemical investigations were urine for albumin, serum creatinine and random serum glucose. CKD suspected patients were subjected to repeat serum creatinine and urinary albumin testing three months after the initial testing to confirm diagnosis of true CKD. Results: 1240 patients of which 650 were males and 590 females, aged between 18 and 65 years were entered into this study. The result evidenced over-all CKD prevalence 19 % determined by Cockcroft-Gault and 19.5 % MDRD equations. Stage 3 CKD was found to be predominant in both Cockcroft-Gault (12.8%) and MDRD equations (13.2%). The risk factors were thought to be associated with CKD which demonstrated association with hypertension (19.3%), diabetes (4.9%) and others (1.3%). A total of 206(88%) patients determined by Cockcroft-Gault and 210 (89.4%) by MDRD equations were diagnosed as having CKD in 2nd follow up visit (3 months after the 1st visit). Conclusion: It appears from this study that one out of three people in this population at risk remained undiag-nosed as CKD and with poorly controlled CKD risk factors. This is a growing problem and a challenge to this country. On priority basis CKD needs to be addressed through the development of multidisciplinary health teams and establishment of improved communication between traditional health care givers and nephrology services. DOI: http://dx.doi.org/10.3329/cbmj.v1i1.13825 Community Based Medical Journal Vol.1(1) 2012 20-26

scholarly journals Elevated Endothelin-1 in Intradialytic Hypertension

2019 ◽  
Vol 7 (2) ◽  
pp. 102-107
Author(s):  
Rubin Surachno Gondodiputro ◽  
Andika Wiratama ◽  
Stefanie Yuliana Usman ◽  
Erma Arnika Dewi ◽  
Evan Susandi ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Observational Study ◽  
Significant Elevation ◽  
Cross Sectional ◽  
Dialysis Unit ◽  
Endothelin 1 ◽  
Before And After ◽  
Relative Change ◽  
Hospital General

Objective: To determine the relative change in endothelin-1 (ET-1) during hemodialysis procedure in Stage Five Dialysis-Dependent Chronic Kidney Disease (CKD-5D)patients with and without intradialytic hypertension (IDH). Methods: This was a cross-sectional, observational study involving 40 CKD-5D patients who received two hemodialysis per week for at least three months at the dialysis unit of Dr. Hasan Sadikin Hospital General Bandung, Indonesia during September 2016. Subjects were divided two groups: with IDH (n=20) and without IDH (n=20). Plasma ET-1 level was examined before and after hemodialysis. Results: There was a significant elevation of ET-1 level (mean±SD pg/mL) between pre- and post-dialysis state in patients with IDH (3.33±1.28 vs. 3.84±1.75; relative changes: 15.32%, p=0.013). No change was observed in patients without IDH (3.99±2.30 vs. 4.38±1.81; relative changes: 9.77% p=0.083). The post-dialysis absolute ET-1 level was significantly lower in CKD-5D patients with IDH (3.84±1.75 vs. 4.38±1.81; p=0.024). Conclusion: There was a significant elevation of ET-1 level in CKD-5D patients with IDH during hemodialysis procedure at the dialysis unit of Dr. Hasan Sadikin General Hospital Bandung.

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