scholarly journals Abnormal skin in toe webs is a marker for abnormal glucose metabolism. A cross-sectional survey among 1,849 adults in Finland

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Suvi-Päivikki Sinikumpu ◽  
Juha Auvinen ◽  
Jari Jokelainen ◽  
Laura Huilaja ◽  
Katri Puukka ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Abnormal Glucose Metabolism

Prevalence and determinants of abnormal glucose metabolism in urban and rural secondary schools in Cameroon: A cross-sectional study in a sub-Saharan Africa setting

2019 ◽  
Vol 13 (4) ◽  
pp. 370-375 ◽  
Author(s):  
Félicité Kamdem ◽  
Daniel Lemogoum ◽  
Ahmadou Musa Jingi ◽  
Stéphane Choupo Guetchuin ◽  
Caroline Kenmegne ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Secondary Schools ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Sectional Study ◽  
Cross Sectional ◽  
Abnormal Glucose Metabolism ◽  
Sub Saharan

scholarly journals The Prevalence of Polycystic Ovarian Syndrome, Metabolic Abnormalities and Its Association With Obesity in Adolescents: A Cross-Sectional Study in an Urban Population in Iran

2020 ◽  
Author(s):  
Azam Azargoon ◽  
Majid Mirmohammadkhani ◽  
Sara Borjian
Keyword(s):  
Metabolic Syndrome ◽  
Glucose Metabolism ◽  
Polycystic Ovary ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Menstrual Dysfunction ◽  
Abnormal Glucose Metabolism ◽  
Multi Stage ◽  
Pcos Group ◽  
History Of

The diagnosis of polycystic ovary syndrome (PCOS) and metabolic syndrome (MS) in adolescents is clinically challenging. It is on the rise as consistent with the increasing trends in obesity rates. This study aimed to investigate the prevalence of PCOS in adolescents by the National Institutes of Health (NIH) criteria and compare the prevalence of insulin resistance (IR) and metabolic syndrome (MS) between obese (OB) and non-obese (NOB) adolescents with PCOS. This was cross-sectional research with multi-stage cluster random sampling. Participants were 15-18-year-old girls from high schools in Semnan, Iran. The ones who had a history of menstrual dysfunction underwent clinical and hormonal tests. From among a total of 900 participants, 74 girls (8.2%) had a history of menstrual dysfunction. The prevalence of PCOS was 6.44% by NIH criteria. The prevalence of abnormal glucose metabolism, MS, and IR in girls with PCOS were 8(13.7%), 6(10.3%), 24(41.4%), respectively. The OB-PCOS group with a mean BMI of 28.21±1.26 kg/m2 had a significantly greater prevalence of MS, high BP, waist circumference ≥88 cm, and higher IR than NOB-PCOS cases with a mean BMI of 20.54±2.97 kg/m2. Abnormal glucose metabolism was prevalent in adolescents with PCOS and occurred with equal frequency in OB and NOB PCOS groups. Obesity could worsen IR, MS, and some of the components of Mets in PCOS adolescents.

scholarly journals Daily Intake and Serum Levels of Copper, Selenium and Zinc According to Glucose Metabolism: Cross-Sectional and Comparative Study

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4044
Author(s):  
Vishwanath Pattan ◽  
Maria Mercedes Chang Villacreses ◽  
Rudruidee Karnchanasorn ◽  
Ken C. Chiu ◽  
Raynald Samoa
Keyword(s):  
Glucose Metabolism ◽  
Glucose Tolerance ◽  
Daily Intake ◽  
Serum Levels ◽  
Zn Deficiency ◽  
Serum Concentrations ◽  
Cross Sectional ◽  
Cu Deficiency ◽  
Abnormal Glucose Metabolism ◽  
Zn Concentration

Trace elements play an important role in metabolism. We compared the daily intake and serum concentrations of copper (Cu), selenium (Se), and zinc (Zn) across a spectrum of glucose tolerance status in a representative U.S. population. Daily intake and serum concentrations of Cu, Zn and Se in 5087 adults from the 2011–2016 National Health and Nutrition Examination Survey (NHANES) were examined and compared to normal (NGT) and abnormal (AGT) glucose tolerance and the presence of diabetes mellitus (DM). Other than Zn deficiency (21.15%), the prevalence of Zn, Se, and Cu excess and Se and Cu deficiency were low (<4.00%). As compared to the NGT group, Cu and Se supplementation was higher in the AGT and DM groups (p < 0.0001 for all). Serum Se and Zn, but not Cu, concentrations were highly correlated with daily intake (p < 0.0001 for both). As compared to the NGT group, serum Cu concentration was highest in the AGT group (p = 0.03), serum Se concentration was highest in the DM group (p < 0.0001), and serum Zn concentration was highest in the AGT group (p < 0.0001). Serum Se and Zn concentration was correlated with daily Se and Zn intake. Even within the reference range for serum Cu, Se, and Zn concentrations, a higher serum concentration of Cu, Se, and Zn was associated with abnormal glucose metabolism. Although the casual relationship remains to be elucidated, these data suggest caution in Cu, Se and Zn supplementation in non-deficient individuals.

scholarly journals Relationship between pancreatic hormones and glucose metabolism: A cross-sectional study in patients after acute pancreatitis

2016 ◽  
Vol 311 (1) ◽  
pp. G50-G58 ◽  
Author(s):  
Sayali A. Pendharkar ◽  
Varsha M. Asrani ◽  
Amy Y. Xiao ◽  
Harry D. Yoon ◽  
Rinki Murphy ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Glucose Metabolism ◽  
Pancreatic Polypeptide ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Pancreatic Hormones ◽  
Sectional Study ◽  
Cross Sectional ◽  
C Peptide ◽  
Abnormal Glucose Metabolism

Abnormal glucose metabolism is present in almost 40% of patients after acute pancreatitis, but its pathophysiology has been poorly investigated. Pancreatic hormone derangements have been sparingly studied to date, and their relationship with abnormal glucose metabolism is largely unknown. The aim was to investigate the associations between pancreatic hormones and glucose metabolism after acute pancreatitis, including the effect of potential confounders. This was a cross-sectional study of 83 adult patients after acute pancreatitis. Fasting venous blood was collected from all patients and used for analysis of insulin, glucagon, pancreatic polypeptide, amylin, somatostatin, C-peptide, glucose, and hemoglobin A1c. Statistical analyses were conducted using the modified Poisson regression, multivariable linear regression, and Spearman's correlation. Age, sex, body mass index, recurrence of acute pancreatitis, duration from first attack, severity, and etiology were adjusted for. Increased insulin was significantly associated with abnormal glucose metabolism after acute pancreatitis, in both unadjusted ( P = 0.038) and adjusted ( P = 0.001) analyses. Patients with abnormal glucose metabolism also had significantly decreased pancreatic polypeptide ( P = 0.001) and increased amylin ( P = 0.047) in adjusted analyses. Somatostatin, C-peptide, and glucagon were not changed significantly in both unadjusted and adjusted analyses. Increased insulin resistance and reduced insulin clearance may be important components of hyperinsulinemic compensation in patients after acute pancreatitis. Increased amylin and reduced pancreatic polypeptide fasting levels characterize impaired glucose homeostasis. Clinical studies investigating islet-cell hormonal responses to mixed-nutrient meal testing and euglycemic-hyperinsulinemic clamps are now warranted for further insights into the role of pancreatic hormones in glucose metabolism derangements secondary to pancreatic diseases.

scholarly journals Significantly decreased islet β cell function and increased fasting plasma glucose in patients with chronic hepatitis B: a cross-sectional study

2021 ◽  
Author(s):  
Dafeng Liu ◽  
Lingyun Zhou ◽  
Xinyi Zhag ◽  
Yilan Zeng ◽  
Lang Bai ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Hepatitis B ◽  
Cell Function ◽  
Cross Sectional Study ◽  
Contributing Factors ◽  
Β Cell ◽  
Cross Sectional ◽  
Abnormal Glucose Metabolism ◽  
Β Cell Function ◽  
Hbeag Status

Abstract Background: The contributing factors of abnormal glucose metabolism and the characteristics of the homeostasis model assessment of β cell function (HOMA-β) value in chronic hepatitis B (CHB) patients are unclear and worth studying.Method: This cross-sectional study recruited 110 CHB patients (CHB group) and 110 patients without hepatitis B virus (non-HBV group); the groups were matched according to sex, age, and body mass index. The contributing factors of abnormal glucose metabolism and the characteristics and differences in glucose metabolism parameters between the two groups were analyzed. Results: The abnormal glucose metabolism rate was higher in CHB patients with liver cirrhosis (LC) and patients with hepatitis B envelope antigen (HBeAg) (-) status. In addition, under the same glucose metabolism conditions, the fasting plasma glucose (FPG) levels of the CHB group was higher than that of the non-HBV group, especially in those with LC that had higher FPG levels (all p=0.000), while the HOMA-β values was significantly lower in the CHB group than in the non-HBV group, especially under normal glucose tolerance conditions (all p=0.000). Further analyses revealed that the main contributing factors of abnormal glucose metabolism were HBeAg (-) status and hepatitis B envelope antibody levels, but HBV serological and virological indicators had no direct effect on the HOMA-β value.Conclusion: These findings provide a reference that will allow clinicians to monitor abnormal glucose metabolism in CHB patients, especially those with LC or HBeAg (-) status, focus on the protection of islet β-cell function, and avoid the application of insulin secretagogues in CHB patients with abnormal glucose metabolism.

scholarly journals Significantly Decreased Islet β Cell Function and Increased Fasting Plasma Glucose in Patients With Chronic Hepatitis B: a Cross-sectional Study

2021 ◽  
Author(s):  
Dafeng Liu ◽  
Lingyun Zhou ◽  
Xinyi Zhang ◽  
Yilan Zeng ◽  
Lang Bai ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Hepatitis B ◽  
Cell Function ◽  
Cross Sectional Study ◽  
Contributing Factors ◽  
Β Cell ◽  
Cross Sectional ◽  
Abnormal Glucose Metabolism ◽  
Β Cell Function ◽  
Hbeag Status

Abstract Background: The contributing factors of abnormal glucose metabolism and the characteristics of the homeostasis model assessment of β cell function (HOMA-β) value in chronic hepatitis B (CHB) patients are unclear and worth studying.Method: This cross-sectional study recruited 110 CHB patients (CHB group) and 110 patients without hepatitis B virus (non-HBV group); the groups were matched according to sex, age, and body mass index. The contributing factors of abnormal glucose metabolism and the characteristics and differences in glucose metabolism parameters between the two groups were analyzed.Results: The abnormal glucose metabolism rate was higher in CHB patients with liver cirrhosis (LC) and patients with hepatitis B envelope antigen (HBeAg) (-) status. In addition, under the same glucose metabolism conditions, the fasting plasma glucose (FPG) levels of the CHB group was higher than that of the non-HBV group, especially in those with LC that had higher FPG levels (all p=0.000), while the HOMA-β values was significantly lower in the CHB group than in the non-HBV group, especially under normal glucose tolerance conditions (all p=0.000). Further analyses revealed that the main contributing factors of abnormal glucose metabolism were HBeAg (-) status and hepatitis B envelope antibody levels, but HBV serological and virological indicators had no direct effect on the HOMA-β value.Conclusion: These findings provide a reference that will allow clinicians to monitor abnormal glucose metabolism in CHB patients, especially those with LC or HBeAg (-) status, focus on the protection of islet β-cell function, and avoid the application of insulin secretagogues in CHB patients with abnormal glucose metabolism.

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