Ideal Cardiovascular Health Metrics on the New Occurrence of Peripheral Artery Disease: A Prospective Cohort Study in Northern China

Abstract Background Evidence on the cardiovascular health effects of cannabis use is limited. We designed a prospective cohort study of older Veterans (66 to 68 years) with coronary artery disease (CAD) to understand the cardiovascular consequences of cannabis use. We describe the cohort construction, baseline characteristics, and health behaviors that were associated with smoking cannabis. Objective To understand the cardiovascular consequences of cannabis use. Design We designed a prospective cohort study of older Veterans (66 to 68 years) with CAD. Participants A total of 1,015 current cannabis smokers and 3,270 non-cannabis smokers with CAD. Main Measures Using logistic regression, we examined the association of baseline variables with smoking cannabis in the past 30 days. Results The current cannabis smokers and non-current smokers were predominantly male (97.2% vs 97.1%, p=0.96). Characteristics associated with recent cannabis use in multivariable analyses included lack of a high school education (odds ratio [OR] 2.15, 95% confidence interval [CI]: 1.10 to 4.19), financial difficulty (OR 1.47, 95% CI: 1.02 to 2.11), tobacco use (OR 3.02, 95% CI: 1.66 to 5.48), current drug use (OR 2.82, 95% CI: 1.06 to 7.46), and prior drug use (OR 2.84, 95% CI: 2.11 to 3.82). In contrast, compared to individuals with 0 to 1 comorbid conditions, those with 5 chronic conditions or more (OR 0.43, 95% CI: 0.27 to 0.70) were less likely to smoke cannabis. Conclusions In this older high-risk cohort, smoking cannabis was associated with higher social and behavioral risk, but with fewer chronic health conditions.

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Ideal Cardiovascular Health Metrics and Incidence of Ischemic Stroke Among Hypertensive Patients: A Prospective Cohort Study

Frontiers in Cardiovascular Medicine ◽

10.3389/fcvm.2020.590809 ◽

2020 ◽

Vol 7 ◽

Author(s):

Yuchen Ying ◽

Shaoyi Lin ◽

Fanqian Kong ◽

Yuying Li ◽

Shujun Xu ◽

...

Keyword(s):

Cohort Study ◽

Ischemic Stroke ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Cardiovascular Health ◽

Southern China ◽

Fasting Blood Glucose ◽

Cox Proportional Hazards ◽

Hypertensive Patients ◽

Ideal Cardiovascular Health

Background: This study aimed to assess the relationship between ideal cardiovascular health (CVH) metrics and incident ischemic stroke (IS) in hypertensive patients, especially those with hyperhomocysteinemia (HHcy).Methods: A prospective cohort study enrolled 5,488 hypertensive patients in Nanshan District of Shenzhen City in southern China from September 2011 to December 2017. CVH metrics were defined according to the American Heart Association. Cox proportional hazards models were used to examine the associations between the number of ideal CVH metrics and the incidence of IS by calculating multivariable-adjusted hazard ratios (HRs) and 95% CI.Results: During an average follow-up of 5.7 years, 340 IS patients were identified. Compared with those having 0 ideal CVH metrics, the HRs (95% CIs) for IS among those with 1, 2, 3, 4, and 5–6 ideal CVH metrics were 0.62 (0.31–1.25), 0.37 (0.19–0.74), 0.37 (0.18–0.74), 0.34 (0.16–0.71), and 0.28 (0.12–0.63), respectively (P < 0.001). An ideal healthy diet score and ideal fasting blood glucose level were independently associated with IS among participants, with HRs (95% CIs) of 0.53 (0.33–0.86) and 0.32 (0.17–0.66), respectively. Additionally, compared with those with normal total homocysteine (tHcy) levels (<15 μmol/L), the HR (95% CI) for IS among participants with HHcy and who had 5–6 ideal CVH metrics was 0.50 (0.27–0.92).Conclusion: An increased number of ideal CVH metrics was inversely associated with the incidence of IS in hypertensive patients. The participants with HHcy who had 5–6 ideal CVH metrics exhibited a lower IS risk than those with normal tHcy levels.

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Hypertension Defined by 2017 ACC/AHA Guideline, Ideal Cardiovascular Health Metrics, and Risk of Cardiovascular Disease: A Nationwide Prospective Cohort Study

The Lancet Regional Health - Western Pacific ◽

10.1016/j.lanwpc.2021.100350 ◽

2022 ◽

Vol 20 ◽

pp. 100350

Author(s):

Shujing Wu ◽

Yu Xu ◽

Ruizhi Zheng ◽

Jieli Lu ◽

Mian Li ◽

...

Keyword(s):

Cardiovascular Disease ◽

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Cardiovascular Health ◽

Ideal Cardiovascular Health

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Predictive value of Galectin-3 for the occurrence of coronary artery disease and prognosis after myocardial infarction and its association with carotid IMT values in these patients: A mid-term prospective cohort study

Atherosclerosis ◽

10.1016/j.atherosclerosis.2016.01.022 ◽

2016 ◽

Vol 246 ◽

pp. 309-317 ◽

Cited By ~ 25

Author(s):

Anna Lisowska ◽

Małgorzata Knapp ◽

Agnieszka Tycińska ◽

Elżbieta Motybel ◽

Karol Kamiński ◽

...

Keyword(s):

Myocardial Infarction ◽

Coronary Artery Disease ◽

Cohort Study ◽

Coronary Artery ◽

Prospective Cohort Study ◽

Predictive Value ◽

Prospective Cohort ◽

Carotid Imt ◽

Galectin 3 ◽

Artery Disease

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Uric Acid Variability and All-Cause Mortality: A Prospective Cohort Study in Northern China

The journal of nutrition health & aging ◽

10.1007/s12603-021-1706-3 ◽

2021 ◽

Author(s):

M. Wang ◽

C. Wang ◽

M. Zhao ◽

Y. Li ◽

S. Yao ◽

...

Keyword(s):

Uric Acid ◽

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Northern China ◽

All Cause Mortality

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Diet and Lifestyle as Risk Factors for Carotid Artery Disease: A Prospective Cohort Study

Cerebrovascular Diseases ◽

10.1159/000510907 ◽

2020 ◽

Vol 49 (5) ◽

pp. 563-569

Author(s):

Anna Johansson ◽

Stefan Acosta

Keyword(s):

Cohort Study ◽

Carotid Artery ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Carotid Artery Disease ◽

Food Diary ◽

Total Study Population ◽

Cox Regression Analysis ◽

Artery Disease ◽

Fish And Shellfish

Background: Stroke is one of the leading causes of death, and out of all stroke cases, 10–15% originate from a previously asymptomatic stenosis in the internal carotid artery. Aims: The aim of the study was to investigate whether dietary and lifestyle habits were associated with future risk of incident carotid artery disease (CAD). Methods: Baseline examinations on middle-aged individuals (n = 30,447) in the Malmö Diet and Cancer study (MDCS), a prospective cohort study, took place between 1991 and 1996 in Malmö, Sweden. Individuals with cardiovascular disease and diabetes mellitus were excluded at baseline, resulting in a total study population of 25,952 patients. Information on dietary intake was gathered through a 7-day food diary, a detailed questionnaire, and a 1-h interview. A diet quality index was calculated from adherence to recommended intake of 6 dietary components (saturated fat, polyunsaturated fat, fish and shellfish, fiber, vegetables and fruit, and sucrose). Individuals with a first registered diagnosis of CAD were identified from the Swedish National Patient register. Results: During a median follow-up of 21.8 years, 469 participants (1.8%) developed CAD. The diagnosis of incident CAD was validated and confirmed in 99% of a random sample of 100 individuals. Higher intake of vegetables and fruit was associated with a trend of decreased risk of CAD in a Cox regression analysis (hazard ratio of 0.76, 95% confidence interval 0.56–1.03; p = 0.080). Conclusions: In conclusion, the present study found a trend toward a protective effect of higher intake of vegetables and fruit against incident CAD. More prospective studies investigating the association between diet and CAD and stroke are needed in order to give firm recommendations.

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