Synthesis of zeolitic imidazolate framework-8 and gold nanoparticles in a sustained out-of-equilibrium state

AbstractThe design and synthesis of crystalline materials are challenging due to the proper control over the size and polydispersity of the samples, which determine their physical and chemical properties and thus applicability. Metal − organic frameworks (MOFs) are promising materials in many applications due to their unique structure. MOFs have been predominantly synthesized by bulk methods, where the concentration of the reagents gradually decreased, which affected the further nucleation and crystal growth. Here we show an out-of-equilibrium method for the generation of zeolitic imidazolate framework-8 (ZIF-8) crystals, where the non-equilibrium crystal growth is maintained by a continuous two-side feed of the reagents in a hydrogel matrix. The size and the polydispersity of the crystals are controlled by the fixed and antagonistic constant mass fluxes of the reagents and by the reaction time. We also present that our approach can be extended to synthesize gold nanoparticles in a redox process.

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Tailoring microstructures of materials through biomimetics

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100148332 ◽

1993 ◽

Vol 51 ◽

pp. 500-501

Author(s):

Mehmet Sarikaya ◽

Ilhan A. Aksay

Keyword(s):

Chemical Properties ◽

Design And Synthesis ◽

Structure Sensitive ◽

Macro Scale ◽

Methods Of Synthesis ◽

Successive Level ◽

Engineering Materials ◽

Physical And Chemical ◽

And Chemical Properties ◽

Synthesis Of Materials

Biomimetics involves investigation of structure, function, and methods of synthesis of biological composite materials. The goal is to apply this information to the design and synthesis of materials for engineering applications.Properties of engineering materials are structure sensitive through the whole spectrum of dimensions from nanometer to macro scale. The goal in designing and processing of technological materials, therefore, is to control microstructural evolution at each of these dimensions so as to achieve predictable physical and chemical properties. Control at each successive level of dimension, however, is a major challenge as is the retention of integrity between successive levels. Engineering materials are rarely fabricated to achieve more than a few of the desired properties and the synthesis techniques usually involve high temperature or low pressure conditions that are energy inefficient and environmentally damaging.In contrast to human-made materials, organisms synthesize composites whose intricate structures are more controlled at each scale and hierarchical order.

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Design and Synthesis of Fluoro Analogues of Vitamin D

International Journal of Molecular Sciences ◽

10.3390/ijms22158191 ◽

2021 ◽

Vol 22 (15) ◽

pp. 8191

Author(s):

Fumihiro Kawagoe ◽

Sayuri Mototani ◽

Atsushi Kittaka

Keyword(s):

Vitamin D ◽

Vitamin D3 ◽

Fluorine Atom ◽

Chemical Properties ◽

Molecular Structures ◽

Physical And Chemical Properties ◽

Design And Synthesis ◽

Synthetic Methodologies ◽

Physical And Chemical ◽

And Chemical Properties

The discovery of a large variety of functions of vitamin D3 and its metabolites has led to the design and synthesis of a vast amount of vitamin D3 analogues in order to increase the potency and reduce toxicity. The introduction of highly electronegative fluorine atom(s) into vitamin D3 skeletons alters their physical and chemical properties. To date, many fluorinated vitamin D3 analogues have been designed and synthesized. This review summarizes the molecular structures of fluoro-containing vitamin D3 analogues and their synthetic methodologies.

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Templated interfacial synthesis of metal-organic framework (MOF) nano- and micro-structures with precisely controlled shapes and sizes

Communications Chemistry ◽

10.1038/s42004-021-00522-1 ◽

2021 ◽

Vol 4 (1) ◽

Author(s):

Lingyao Meng ◽

Binyu Yu ◽

Yang Qin

Keyword(s):

Crystal Growth ◽

Metal Organic Framework ◽

Reaction Conditions ◽

Zeolitic Imidazolate Framework ◽

Crystallographic Preferred Orientation ◽

Metal Organic ◽

Interfacial Synthesis ◽

Oil Water ◽

Synthesis Methodology ◽

Micro Structures

AbstractMetal-organic frameworks (MOF) are an emerging class of microporous materials with promising applications. MOF nanocrystals, and their assembled super-structures, can display unique properties and reactivities when compared with their bulk analogues. MOF nanostructures of 0-D, 2-D, and 3-D dimensions can be routinely obtained by controlling reaction conditions and ligand additives, while formation of 1-D MOF nanocrystals (nanowires and nanorods) and super-structures has been relatively rare. We report here a facile templated interfacial synthesis methodology for the preparation of a series of 1-D MOF nano- and micro-structures with precisely controlled shapes and sizes. Specifically, by applying track-etched polycarbonate (PCTE) membranes as the templates and at the oil/water interface, we rapidly and reproducibly synthesize zeolitic imidazolate framework-8 (ZIF-8) and ZIF-67 nano- and micro structures of sizes ranging from 10 nm to 20 μm. We also identify a size confinement effect on MOF crystal growth, which leads to single crystals under the most restricted conditions and inter-grown polycrystals at larger template pore sizes, as well as surface directing effects that influence the crystallographic preferred orientation. Our findings provide a potentially generalizable method for controlling the size, morphology, and crystal orientations of MOF nanomaterials, as well as offering fundamental understanding into MOF crystal growth mechanisms.

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Green Silver and Gold Nanoparticles: Biological Synthesis Approaches and Potentials for Biomedical Applications

Molecules ◽

10.3390/molecules26040844 ◽

2021 ◽

Vol 26 (4) ◽

pp. 844 ◽

Cited By ~ 2

Author(s):

Andrea Rónavári ◽

Nóra Igaz ◽

Dóra I. Adamecz ◽

Bettina Szerencsés ◽

Csaba Molnar ◽

...

Keyword(s):

Gold Nanoparticles ◽

Biomedical Applications ◽

Biological Activities ◽

Large Body ◽

Chemical Properties ◽

Biological Synthesis ◽

Silver And Gold Nanoparticles ◽

Comprehensive Collection ◽

Synthetic Approaches ◽

Physical And Chemical

The nanomaterial industry generates gigantic quantities of metal-based nanomaterials for various technological and biomedical applications; however, concomitantly, it places a massive burden on the environment by utilizing toxic chemicals for the production process and leaving hazardous waste materials behind. Moreover, the employed, often unpleasant chemicals can affect the biocompatibility of the generated particles and severely restrict their application possibilities. On these grounds, green synthetic approaches have emerged, offering eco-friendly, sustainable, nature-derived alternative production methods, thus attenuating the ecological footprint of the nanomaterial industry. In the last decade, a plethora of biological materials has been tested to probe their suitability for nanomaterial synthesis. Although most of these approaches were successful, a large body of evidence indicates that the green material or entity used for the production would substantially define the physical and chemical properties and as a consequence, the biological activities of the obtained nanomaterials. The present review provides a comprehensive collection of the most recent green methodologies, surveys the major nanoparticle characterization techniques and screens the effects triggered by the obtained nanomaterials in various living systems to give an impression on the biomedical potential of green synthesized silver and gold nanoparticles.

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Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems

The Analyst ◽

10.1039/c8an02070a ◽

2019 ◽

Vol 144 (4) ◽

pp. 1052-1072 ◽

Cited By ~ 19

Author(s):

Yanjing Yang ◽

Shian Zhong ◽

Kemin Wang ◽

Jin Huang

Keyword(s):

Gold Nanoparticles ◽

Gold Nanoparticle ◽

Chemical Properties ◽

Living Systems ◽

Oligonucleotide Probes ◽

Physical And Chemical Properties ◽

Physical And Chemical ◽

And Chemical Properties

Gold nanoparticles (AuNPs) with unique physical and chemical properties have become an integral part of research in nanoscience.

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Tuning Packing, Structural Flexibility, and Porosity in 2D Metal–Organic Frameworks by Metal Node Choice

Australian Journal of Chemistry ◽

10.1071/ch19215 ◽

2019 ◽

Vol 72 (10) ◽

pp. 797 ◽

Cited By ~ 2

Author(s):

Witold M. Bloch ◽

Christian J. Doonan ◽

Christopher J. Sumby

Keyword(s):

Structural Changes ◽

Metal Organic Frameworks ◽

Chemical Properties ◽

Complete Removal ◽

Structural Flexibility ◽

X Ray Diffraction ◽

Metal Centre ◽

Metal Organic ◽

Physical And Chemical ◽

And Chemical Properties

Understanding the key features that determine structural flexibility in metal–organic frameworks (MOFs) is key to exploiting their dynamic physical and chemical properties. We have previously reported a 2D MOF material, CuL1, comprising five-coordinate metal nodes that displays exceptional CO2/N2 selectively (L1=bis(4-(4-carboxyphenyl)-1H-pyrazolyl)methane). Here we examine the effect of utilising six-coordinate metal centres (CoII and NiII) in the synthesis of isostructural MOFs from L1, namely CoL1 and NiL1. The octahedral geometry of the metal centre within the MOF analogues precludes an ideal eclipse of the 2D layers, resulting in an offset stacking, and in certain cases, the formation of 2-fold interpenetrated analogues β-CoL1 and β-NiL1. We used a combination of thermogravimetric analysis (TGA), and powder and single crystal X-ray diffraction (PXRD and SCXRD) to show that desolvation is accompanied by a structural change for NiL1, and complete removal of the coordinated H2O ligands results in a reduction in long-range order. The offset nature of the 2D layers in combination with the structural changes impedes the adsorption of meaningful quantities of gases (N2, CO2), highlighting the importance of a five-coordinate metal centre in achieving optimal pore accessibility for this family of flexible materials.

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Superphanes: Old Yet New Binding–Agents for Highly Selective Recognition of Fluoride by Size–Sieving Effect

10.26434/chemrxiv.13489608 ◽

2020 ◽

Author(s):

Qing He ◽

Aimin Li ◽

Shenglun Xiong ◽

Wei Zhou ◽

Huijuan Zhai ◽

...

Keyword(s):

Chemical Properties ◽

Three Dimensions ◽

High Symmetry ◽

X Ray Crystallography ◽

Design And Synthesis ◽

Binding Agents ◽

Physical And Chemical ◽

And Chemical Properties ◽

Sieving Effect ◽

Guest Chemistry

Superphanes, namely percyclophanes, have been widely investigated for the sake of their aesthetically pleasing structures with high symmetry, intriguing physical and chemical properties and synthetic challenges. Nonetheless, the host–guest chemistry of superphanes remains to be an unmet challenge. Herein, we delineate the design, preparation, characterization, and host–guest chemistry of an unprecedented superphane 15, which was evidenced by mass spectroscopy, NMR spectroscopy, X–ray crystallography, and DFT calculations. 15 features six bridges between two benzene planes, up to 18 Csp–H hydrogen–bonding donors well–distributed around the near–closed inner cavity in three dimensions. These allow 15 to exhibit exclusive selectivity towards F– against Cl–, Br–, I–, N3–, SCN–, NO3–, ClO4–, SO42– and HP2O73– due to the size–sieving effect. This contribution opens up new opportunities for design and synthesis of new supramolecular hosts for anions of interest with high selectivity.

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Targeted Chemotherapy Delivery via Gold Nanoparticles: A Scoping Review of In Vivo Studies

Crystals ◽

10.3390/cryst11101169 ◽

2021 ◽

Vol 11 (10) ◽

pp. 1169

Author(s):

Ștefan Morărașu ◽

Ștefan Iacob ◽

Ionuț Tudorancea ◽

Sorinel Luncă ◽

Mihail-Gabriel Dimofte

Keyword(s):

Gold Nanoparticles ◽

Cancer Treatment ◽

Chemical Properties ◽

In Vivo Studies ◽

Synthesis Methods ◽

Experimental Cancer ◽

Therapy Option ◽

Physical And Chemical ◽

System Toxicity

In the field of oncology, a lot of improvements in nanotechnology creates support for better diagnosis and therapeutic opportunities, and due to their physical and chemical properties, gold nanoparticles are highly applicable. We performed a literature review on the studies engaging the usage of gold nanoparticles on murine models with a focus on the type of the carrier, the chemotherapy drug, the target tumoral tissue and outcomes. We identified fifteen studies that fulfilled our search criteria, in which we analyzed the synthesis methods, the most used chemotherapy conjugates of gold nanoparticles in experimental cancer treatment, as well as the improved impact on tumor size and system toxicity. Due to their intrinsic traits, we conclude that chemotherapy conjugates of gold nanoparticles are promising in experimental cancer treatment and may prove to be a safer and improved therapy option than current alternatives.

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Fluorinated Organic Porous Materials

Organic Materials ◽

10.1055/s-0039-1698431 ◽

2019 ◽

Vol 01 (01) ◽

pp. 019-029 ◽

Cited By ~ 3

Author(s):

Zhenglin Zhang ◽

Ognjen Š. Miljanić

Keyword(s):

Porous Materials ◽

Organic Molecules ◽

Metal Organic Frameworks ◽

Molecular Crystals ◽

Chemical Properties ◽

Physical And Chemical Properties ◽

Metal Organic ◽

Physical And Chemical ◽

And Chemical Properties

Fluorine is in many aspects unique among the elements, and its incorporation into organic molecules can dramatically change their physical and chemical properties. This minireview will survey the existing classes of fluorinated porous materials, with a particular focus on all-organic porous materials. We will highlight our work on the preparation and study of metal–organic frameworks and porous molecular crystals derived from extensively fluorinated rigid aromatic pyrazoles and tetrazoles. Where possible, comparisons between fluorinated and nonfluorinated materials will be made.

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Thiol Decorated Defective Metal-Organic Framework Embedded with Palladium Nanoparticles for Efficient Cr(VI) Reduction

Inorganic Chemistry Frontiers ◽

10.1039/d1qi00759a ◽

2021 ◽

Author(s):

Sukhendu Mandal ◽

Asha P. ◽

R. K. Aparna ◽

Balu P Ratheesh ◽

Manju M Maman

Keyword(s):

Palladium Nanoparticles ◽

Metal Organic Framework ◽

Chemical Properties ◽

Physical And Chemical Properties ◽

Metal Organic ◽

Physical And Chemical ◽

And Chemical Properties ◽

Organic Framework

Engineering defective UiO-66 with functionalized modulator may create functionality with promising physical and chemical properties. Herein, we use 2-mercaptobenzoic acid (2-MBA) as a modulator for the functionalization of defective UiO-66...

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