scholarly journals Asymptomatic secondary hyperparathyroidism can mimic sacroiliitis on computed tomography

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Virginie Kreutzinger ◽  
Torsten Diekhoff ◽  
Lutz Liefeldt ◽  
Denis Poddubnyy ◽  
Kay Geert A. Hermann ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Secondary Hyperparathyroidism ◽  
Demographic Data ◽  
Joint Space ◽  
Electronic Patient Records ◽  
Retrospective Case ◽  
High Resolution Computed Tomography ◽  
Asymptomatic Patients ◽  
Control Study

AbstractSecondary hyperparathyroidism (sHPT) as a result of chronic kidney disease (CKD) is a common health problem and has been reported to manifest at the sacroiliac joints (SIJ). The aim of this investigation was to systematically assess sacroiliac joint changes in asymptomatic sHPT as detected by high-resolution CT. Included in this IRB-approved retrospective case–control study were 56 patients with asymptomatic sHPT as well as 259 matched controls without SIJ disease. Demographic data were retrieved from electronic patient records. High-resolution computed tomography datasets of all patients were subjected to a structured scoring, including erosions, sclerosis, osteophytes, joint space alterations and intraarticular calcifications. Chi2 tests were used to compare frequencies of lesions. Erosions were significantly more prevalent in patients with sHPT, and were found mainly in the ventral (28.6% vs. 13.9%; p = 0.016) and middle (17.9% vs. 7.7%; p = 0.040) iliac portions of the SIJ. Partial ankylosis was rare in both cohorts (3.6% vs. 5.0%; p > 0.999); complete ankylosis was not observed. Neither extent not prevalence of sclerosis or calcifications differed significantly between groups. Joint lesions reminiscent of sacroiliitis can be found in a substantial portion of asymptomatic patients with secondary hyperparathyroidism. Further investigations into the clinical significance of these findings are warranted.

Sensitivity of High-Resolution Computed Tomography in Otosclerosis Patients undergoing Primary Stapedotomy

2020 ◽  
Vol 129 (9) ◽  
pp. 918-923
Author(s):  
Anne K. Maxwell ◽  
Mohamed Hosameldeen Shokry ◽  
Adam Master ◽  
William H. Slattery
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Demographic Data ◽  
Retrospective Chart Review ◽  
Time Frame ◽  
High Resolution Computed Tomography ◽  
Acoustic Reflexes ◽  
Negative Report ◽  
Unexplained Symptoms ◽  
Rule Out

Objective: To determine the incidence of abnormal otospongiotic or otosclerotic findings on high-resolution computed tomography (HRCT) as read by local radiologists in patients with surgically-confirmed otosclerosis. Study design: Retrospective chart review. Setting: Tertiary-referral private otology-neurotology practice. Patients: Adults (>18 years old) with surgically-confirmed otosclerosis between 2012 and 2017 with a HRCT performed preoperatively. Intervention: Preoperative HRCT then stapedotomy. Main outcome measures: Positive identification and location of radiographic otosclerosis as reported by the local radiologist. We then correlated the CT with surgical location as documented at time of surgery. Audiometry, demographic data, intraoperative findings, and surgical technique were secondarily reviewed. Results: Of the 708 stapes surgeries were performed during the study time frame. Preoperative HRCT scans were available for 68 primary stapedotomy surgeries performed in 54 patients. Otosclerosis was reported in 20/68 (29.4%). Following a negative report by the local radiologist, a re-review by the surgeon and/or collaborating neuroradiologist confirmed otosclerosis in 12/48 additional cases (25.0%). There was an overall sensitivity of 47.1%. Intraoperatively, cases with negative reads tended to have more limited localization at the ligament (8.7%) or anterior crus (39.1%), compared with positive reads, which demonstrated more extensive involvement, with bipolar foci (30.0%) or diffuse footplate manifestations (20.0%) more common. Acoustic reflexes were characteristically absent. Conclusions: While HRCT may aid in the diagnosis of otosclerosis and rule out concomitant pathology in certain cases of clinical uncertainty or unexplained symptoms, its sensitivity for otosclerosis remains low. HRCT should not be relied upon to diagnose routine fenestral otosclerosis.

scholarly journals Impact of age, sex, and joint form on degenerative lesions of the sacroiliac joints on CT in the normal population

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Katharina Ziegeler ◽  
Virginie Kreutzinger ◽  
Torsten Diekhoff ◽  
Robert Roehle ◽  
Denis Poddubnyy ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Normal Population ◽  
Demographic Data ◽  
Age Groups ◽  
Joint Space ◽  
Common Finding ◽  
Electronic Patient Records ◽  
Sacroiliac Joints ◽  
High Resolution Computed Tomography ◽  
Joint Form

AbstractDegeneration of the sacroiliac joints (SIJs) is a common finding, while its underlying cause and development remain incompletely understood. The aim of this investigation was to describe the spatial distribution of degenerative SIJ changes across age groups and to investigate for the first time their relationship to anatomical form and sex. For this IRB-approved investigation, demographic data of 818 patients without SIJ disease were retrieved from electronic patient records. High-resolution computed tomography (CT) datasets of all patients were analysed retrospectively for seven predefined age groups (ten-year increments, from < 25 to ≥ 75). A structured scoring system was applied to assess sclerosis, osteophytes, joint space alterations, and anatomical form. Chi-square tests were used to compare frequencies of degenerative lesions, and logistic regression analyses were performed to investigate associations between demographic data, anatomical form, and the presence of structural lesions. Sclerosis and osteophytes were common findings, with an overall prevalence of 45.7% and 46.8%, respectively. Female sex had an odds ratio (OR) of 0.15 (95% CI: 0.08–0.27) for the presence of ventral osteophytes and of 4.42 (95% CI: 2.77–7.04) for dorsal osteophytes. Atypical joint forms were significantly more prevalent in women with 62.1% vs. 14.1% in men (p < 0.001). Accessory joints increased the likelihood of dorsal sclerosis (OR 2.735; 95% CI 1.376–5.436) while a typical joint form decreased its likelihood (OR 0.174; 95% CI 0.104–0.293). Sex and anatomical joint form have a major impact on the development of degenerative lesions of the SIJs and their spatial distribution.

scholarly journals A Normal Range of KL-6/MUC1 Independent of Elevated SP-D Indicates a Better Prognosis in the Patients with Honeycombing on High-Resolution Computed Tomography

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Shu Hisata ◽  
Yuichiro Kimura ◽  
Naoko Shibata ◽  
Shuichi Ono ◽  
Takao Kobayashi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Prognostic Value ◽  
Respiratory Symptoms ◽  
Immunohistochemical Analysis ◽  
The Other ◽  
Normal Range ◽  
High Resolution Computed Tomography ◽  
Asymptomatic Patients ◽  
Independent Effects

Both SP-D and KL-6/MUC1 are established biomarkers of the interstitial pneumonias, including idiopathic pulmonary fibrosis (IPF), but the causes and clinical outcomes based on their independent effects are not known. Eleven asymptomatic patients, detected with honeycombing on high-resolution computed tomography (HRCT), were compared with 17 other IPF outpatients having slight respiratory symptoms and honeycombing as well. Although SP-D was increased in both groups, KL-6 was significantly higher in the symptomatic IPF group. When the patients (n=11) having both biomarkers elevated were compared with the other patients (n=6) with only SP-D elevated, the distribution of fibrotic lesions with honeycombing on HRCT was larger and the survival time was shorter in the patients having both biomarkers elevated. Immunohistochemical analysis also differentiated these biomarkers in the lung. These results suggest both a cause and the prognostic value of dissociation of these biomarkers.

Acute Pulmonary Oxygen Toxicity in Rats: Findings and Lung Density Changes in High Resolution Computed Tomography

2000 ◽  
Vol 42 (3) ◽  
pp. 473
Author(s):  
Dae Sik Ryu ◽  
Kun Sang Kim ◽  
Kil Hyen Kang ◽  
Haing Sup Chung ◽  
Bung Wok Lee ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Oxygen Toxicity ◽  
High Resolution Computed Tomography ◽  
Lung Density

Determination of the Activity of Pulmonary Tuberculosis: the Utility of High-Resolution Computed Tomography

2000 ◽  
Vol 42 (5) ◽  
pp. 757
Author(s):  
Myung Hee Chung ◽  
Hae Giu Lee ◽  
Won Jong Yu ◽  
Hong Jun Chung ◽  
Bo Sung Yang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Pulmonary Tuberculosis ◽  
High Resolution Computed Tomography

Bone marrow densitometry by clinical high resolution computed tomography of human vertebrae

2014 ◽  
Author(s):  
Jaime Pena ◽  
Graeme Campbell ◽  
Timo Damm ◽  
Reinhard Barkmann ◽  
Sonja Waldhausen ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Marrow ◽  
High Resolution ◽  
High Resolution Computed Tomography

Computed tomography in diagnosis of silicosis

2019 ◽  
pp. 39-41
Author(s):  
Alina S. Kovaleva ◽  
Igor V. Bukhtiyarov ◽  
Natalya S. Serova ◽  
Tatyana B. Burmistrova
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Respiratory System ◽  
Evidence Based Medicine ◽  
Occupational Disease ◽  
Occupational Medicine ◽  
Occupational Diseases ◽  
Evidence Based ◽  
High Resolution Computed Tomography ◽  
Based Medicine

Respiratory system diseases are one of the main problems in contemporary occupational medicine and exceed one fifth of all occupational diseases. Objective of the review was search and analysis of literature on diagnosis of silicosis as an important occupational disease of respiratory organs, by computed tomography and high-resolution computed tomography, from evidence-based medicine viewpoint.

High Resolution Computed Tomography of Auditory Ossicles

1990 ◽  
Vol 31 (1) ◽  
pp. 27-31
Author(s):  
M. Isono ◽  
K. Murata ◽  
F. Ohta ◽  
A. Yoshida ◽  
O. Ishida
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
High Resolution Computed Tomography ◽  
Auditory Ossicles
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