scholarly journals Impact of acute ethanol intake on cardiac autonomic regulation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Stefan Brunner ◽  
Raphaela Winter ◽  
Christina Werzer ◽  
Lukas von Stülpnagel ◽  
Ina Clasen ◽  
...  
Keyword(s):  
Heart Rate ◽  
Alcohol Concentration ◽  
Qtc Interval ◽  
Cardiac Autonomic Nervous System ◽  
Alcohol Administration ◽  
Autonomic Imbalance ◽  
Cardiac Autonomic Regulation ◽  
Acute Ethanol ◽  
Baseline Levels ◽  
Mean Heart Rate

AbstractAcute alcohol consumption may facilitate cardiac arrhythmias underlying the ‘Holiday Heart Syndrome’. Autonomic imbalance is promoting atrial arrhythmias. We analyzed the effects of alcohol on measures of the cardiac autonomic nervous system and their relation to arrhythmias. In 15 healthy individuals, alcohol was administered parenterally until a breath alcohol concentration of 0.50 mg/l. High-resolution digital 30-min ECGs were recorded at baseline, at the time of maximum alcohol concentration, and after alcohol concentration returned to near baseline. Using customized software, we assessed periodic repolarization dynamics (PRD), deceleration capacity (DC), standard measures of heart rate variability (SDNN; RMSSD; LF; HF), and standard ECG parameters (mean heart rate; PQ; QRS; QTc interval). At the maximum alcohol concentration, PRD levels were significantly increased compared to baseline [1.92 (IQR 1.14–3.33) deg2 vs. 0.85 (0.69–1.48) deg2; p = 0.001]. PRD levels remained slightly increased when alcohol concentrations returned to baseline. DC levels were significantly decreased at the maximum alcohol concentration compared to baseline [7.79 (5.89–9.62) ms vs. 9.97 (8.20–10.99) ms; p = 0.030], and returned to baseline levels upon reaching baseline levels of alcohol. Standard HRV measures were reduced at maximum alcohol concentration. The mean heart rate increased significantly during alcohol administration. QRS and QTc duration were significantly prolonged, whereas PQ interval showed no change. Our findings revealed an increase of sympathetic activity and a reduction of parasympathetic activity under the influence of alcohol administration, resulting in autonomic imbalance. This imbalance might ultimately trigger arrhythmias underlying the ‘Holiday Heart Syndrome’.

Circadian blood pressure and heart rate rhythms in mice

1999 ◽  
Vol 276 (2) ◽  
pp. R500-R504 ◽  
Author(s):  
Ping Li ◽  
Steven H. Sur ◽  
Ralph E. Mistlberger ◽  
Mariana Morris
Keyword(s):  
Heart Rate ◽  
Sampling Rate ◽  
Eating Patterns ◽  
Cardiovascular Parameters ◽  
C57bl Mice ◽  
Weight Analysis ◽  
Using Data ◽  
Computerized Monitoring ◽  
Carotid Arterial ◽  
Mean Heart Rate

The circadian pattern of mean arterial pressure (MAP) and heart rate (HR) was measured in C57BL mice with carotid arterial catheters. Cardiovascular parameters were recorded continuously with a computerized monitoring system at a sampling rate of 100 Hz. The tethered animals were healthy, showing stabilized drinking and eating patterns within 2 days of surgery and little loss of body weight. Analysis of the 24-h pattern of MAP and HR was conducted using data from 3–6 consecutive days of recording. A daily rhythm of MAP was evident in all mice, with group mean dark and light values of 101.4 ± 7.3 and 93.1 ± 2.9 mmHg, respectively. The group mean waveform was bimodal, with peak values evident early and late in the dark period, and a trough during the middle of the light period. The phase of maximum and minimum values showed low within-group variance. Mean heart rate was greater at night than during the day (561.9 ± 22.7 vs. 530.3 ± 22.3 beats/min). Peak values generally occurred at dark onset, and minimum values during the middle of both the dark and the light periods. We conclude that it is possible to perform measurements of circadian cardiovascular parameters in the mouse, providing new avenues for the investigation of genetic models.

Heart rate responses and plasma cortisol concentrations in ewes: comparison between cervical and laparoscopic intrauterine insemination and their associated handling procedures

1998 ◽  
Vol 66 (2) ◽  
pp. 383-387 ◽  
Author(s):  
M. Khalid ◽  
W. Haresign ◽  
D. G. Bradley
Keyword(s):  
Heart Rate ◽  
Stress Responses ◽  
Plasma Cortisol ◽  
Intrauterine Insemination ◽  
Management Practice ◽  
Treatment Groups ◽  
Cortisol Responses ◽  
The Mean ◽  
Pre Treatment ◽  
Mean Heart Rate

AbstractThis study consisted of two experiments. In experiment 1, stress responses of sheep which were restrained either in a laparoscopy cradle or a roll-over cradle were compared. The results of this experiment indicated that restraint in roll-over cradle is less (P < 0·05) stressful than that in a laparoscopy cradle when assessed in terms of the elevation and duration of both the mean heart rate and plasma cortisol responses. Experiment 2 compared the stress responses of sheep subjected to restraint in a laparoscopy cradle, restraint in a laparoscopy cradle with intrauterine artificial insemination (AI) by laparoscopy, minimal restraint with cervical AI or restraint in a roll-over cradle plus foot-trimming. All treatments resulted in significant elevations in both heart rate and plasma cortisol concentrations (F < 0·001). The peak heart rate was significantly (P < 0·05) higher in ewes subjected to cervical AI than in those subjected to intrauterine insemination, with other treatments intermediate. The peak cortisol response did not differ among different treatments. The duration over which both the mean heart rate and -plasma cortisol concentrations remained significantly elevated above pre-treatment concentrations did not differ among treatment groups. The results of this study suggest that while restraint using a laparoscopy cradle is more stressful than that using a rollover cradle, the stress inflicted by intrauterine insemination by laparoscopy itself is no greater than that due to restraint using the laparoscopy cradle alone, cervical AI or the management practice offoot-trimming using a rollover cradle.

scholarly journals Assessment of Cardiac Autonomic Nervous System Involvement in Systemic Sclerosis via Exercise Heart Rate Recovery

2014 ◽  
Vol 24 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Ugur Nadir Karakulak ◽  
Sercan Okutucu ◽  
Levent Şahiner ◽  
Naresh Maharjan ◽  
Elifcan Aladag ◽  
...  
Keyword(s):  
Heart Rate ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Systemic Sclerosis ◽  
Heart Rate Recovery ◽  
Exercise Heart Rate ◽  
Cardiac Autonomic Nervous System ◽  
System Involvement ◽  
Autonomic Nervous

Normative Arm and Calf Blood Pressure Values in the Newborn

PEDIATRICS ◽  
1989 ◽  
Vol 83 (2) ◽  
pp. 240-243
Author(s):  
Myung K. Park ◽  
Da-Hae Lee
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Mexican Americans ◽  
Newborn Infants ◽  
Coarctation Of The Aorta ◽  
Upper Arm ◽  
Mean Values ◽  
The Right ◽  
Diagnosis Of Hypertension ◽  
Mean Heart Rate

Indirect BP measurement was obtained in the right upper arm in 219 healthy newborn infants with the Dinamap monitor and was compared with values obtained from the calf to establish normative BP values and to help establish a diagnosis of hypertension and coarctation of the aorta in the newborn. There were 174 Mexican-Americans (79.5%), 33 whites (15.0%), and 12 blacks (5.5%). The width of the BP cuff was selected to be 0.4 to 0.5 times the circumference of the extremities. Three supine position readings of BPs and heart rate were obtained from each site and were averaged for statistical analyses. Mean arm BP values (±SD) of the neonate less than 36 hours of age were 62.6±6.9/38.9± 5.7 mm Hg (48.0±6.2 mm Hg). Neonates older than 36 hours had slightly but significantly (P&lt;.05) greater values (4 to 6 mm Hg) than did infants younger than 36 hours of age. Active neonates had values 6 to 10 mm Hg greater than quiet neonates (P&lt;.05). BP values in the calf obtained with the same-sized cuff were almost identical with those obtained from the arm. Differences in consecutively obtained arm and calf BPs (arm values minus calf values) were 1.1±7.7 mm Hg systolic, -0.01 ± 6.2 mm Hg diastolic, and 0.9 ±6.9 mm Hg mean pressures. Mean heart rate (±SD) of neonates less than 36 hours of age was 129.4± 13.2 beats per minute and that of neonates older than 36 hours of age was 139.4± 14.1 beats per minute. These results show the following: (1) arm BPs and calf BPs using the same-sized cuff are almost identical with mean values of approximately 65/ 41 mm Hg (50 mm Hg) in neonates one to three days of age, (2) arm BP of 75/49 mm Hg (59 mm Hg) or greater is in the hypertensive range, and (3) calf BPs that are less than arm BPs by mean + 1 SD (6 to 9 mm Hg) necessitate a thorough investigation for coarctation of the aorta.

Renal denervation alters cardiovascular and endocrine responses to hemorrhage in conscious newborn lambs

1998 ◽  
Vol 275 (1) ◽  
pp. H285-H291 ◽  
Author(s):  
Francine G. Smith ◽  
Isam Abu-Amarah
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Renal Denervation ◽  
Plasma Renin ◽  
Sympathetic Nerves ◽  
Renal Nerves ◽  
Elevated Plasma ◽  
Baseline Levels ◽  
Renal Sympathetic

To investigate the role of renal sympathetic nerves in modulating cardiovascular and endocrine responses to hemorrhage early in life, we carried out three experiments in conscious, chronically instrumented lambs with intact renal nerves (intact; n = 8) and with bilateral renal denervation (denervated; n = 5). Measurements were made 1 h before and 1 h after 0, 10, and 20% hemorrhage. Blood pressure decreased transiently after 20% hemorrhage in intact lambs and returned to control levels. In denervated lambs, however, blood pressure remained decreased after 60 min. After 20% hemorrhage, heart rate increased from 170 ± 16 to 207 ± 18 beats/min in intact lambs but not in denervated lambs, in which basal heart rates were already elevated to 202 ± 21 beats/min. Despite an elevated plasma renin activity (PRA) measured in denervated (12.0 ± 6.4 ng ANG I ⋅ ml−1 ⋅ h−1) compared with intact lambs (4.0 ± 1.1 ng ANG I ⋅ ml−1 ⋅ h−1), the increase in PRA in response to 20% hemorrhage was similar in both groups. Plasma levels of arginine vasopressin increased from 11 ± 8 to 197 ± 246 pg/ml after 20% hemorrhage in intact lambs but remained unaltered in denervated lambs from baseline levels of 15 ± 10 pg/ml. These observations provide evidence that in the newborn, renal sympathetic nerves modulate cardiovascular and endocrine responses to hemorrhage.

Postprandial Metabolic Effects of Accelerometer Measured Spontaneous Low-Level Activity

2015 ◽  
Vol 12 (8) ◽  
pp. 1133-1138 ◽  
Author(s):  
Meredith C. Peddie ◽  
Claire Cameron ◽  
Nancy Rehrer ◽  
Tracy Perry
Keyword(s):  
Heart Rate ◽  
Glucose Metabolism ◽  
Sedentary Time ◽  
Area Under The Curve ◽  
Postprandial Glucose ◽  
Metabolic Effects ◽  
Negative Effects ◽  
Prolonged Sitting ◽  
Total Movement ◽  
Mean Heart Rate

Background:Interrupting sedentary time induces improvements in glucose metabolism; however, it is unclear how much activity is required to reduce the negative effects of prolonged sitting.Methods:Sixty-six participants sat continuously for 9 hours except for required bathroom breaks. Participants were fed meal replacement beverages at 60, 240 and 420 min. Blood samples were obtained hourly for 9 hours, with additional samples collected 30 and 45 min after each feeding. Responses were calculated as incremental area under the curve (iAUC) for plasma glucose, insulin and triglyceride. Participants wore a triaxial accelerometer and a heart rate monitor. Energy expenditure was estimated using indirect calorimetry.Results:After controlling for age, sex and BMI, every 100 count increase in accelerometer derived total movement was associated with a 0.06 mmol·L-1·9 hours decrease in glucose iAUC (95% CI 0.004–0.1; P = .035), but not associated with changes in insulin or triglyceride iAUC. Every 1 bpm increase in mean heart rate was associated with a 0.76 mmol·L-1·9 hours increase in triglyceride iAUC (95% CI 0.13–1.38).Conclusion:Accelerometer measured movement during periods of prolonged sitting can result in minor improvements in postprandial glucose metabolism, but not lipid metabolism.

scholarly journals Srdeční frekvence sportovců s mentálním postižením během zápasů národního turnaje ve stolním tenise Českého hnutí speciálních olympiád: pilotní studie

2019 ◽  
Vol 12 (2) ◽  
pp. 26-32 ◽  
Author(s):  
Marta Gimunová ◽  
Hana Válková ◽  
Tomáš Kalina
Keyword(s):  
Heart Rate ◽  
Intellectual Disabilities ◽  
Correlation Coefficients ◽  
The Body ◽  
Table Tennis ◽  
Special Olympics ◽  
Individual Fitness ◽  
Relationship Of ◽  
Overweight Or Obesity ◽  
Mean Heart Rate

Heart rate values are considered to be a significant indicator of individual fitness, intensity of exerciseand sympathetic activation. There are few studies in Czech literature focused on the heart rate in athleteswith intellectual disabilities. The aim of this study was to describe the characteristics of heart rateduring fifteen table tennis matches within the 23rd national tournament of the Czech Special OlympicsMovement. Ten participants (6 males, 4 females) who for at least 3 years train regularly and participatein table tennis competitions under the Special Olympics rules, were observed. Their heart rate wasmeasured using a sports tester Forerunner® 15, Garmin Ltd, which was fastened on the participant’schest during their game day. Heart rate values during the matches were statistically processed alongwith the matches’ duration and the resulting match scores. Correlation coefficients obtained from scatterplots show a statistically significant relationship of mean heart rate values during the match withthe resulting score, probably influenced by emotion and psychological stress associated with the matchloss. The effect of match duration on the heart rate was not statistically significant during observedmatches. Subsequent analysis of the body composition of the athletes showed that sixty percent ofthem were in the category of overweight or obesity. These results highlight the need to promote healthylifestyle and physical activity in the population with intellectual disabilities.

scholarly journals Diurnal Corrected QT Interval and QT Dispersion Variation in Non-Alcoholic Cirrhotic Patients and Healthy Control: A Case-Control Study, Iran

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Taghi Amiriani ◽  
Vahid Khori ◽  
Ali Davarian ◽  
Niloofar Rajabli ◽  
Mahsa Niknam ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Diurnal Variation ◽  
Healthy Subjects ◽  
Alcoholic Cirrhosis ◽  
Qt Dispersion ◽  
Qtc Interval ◽  
Healthy Controls ◽  
Cirrhotic Patients ◽  
The Mean

Background: Cirrhosis could lead to a long corrected QT (QTc) interval in a subgroup of patients, but there are spare data on its diurnal variation. Objectives: The present study aimed to determine the diurnal variation of QTc interval and its relationship to heart rate and blood pressure variation during 24-hour Holter-monitoring in non-alcoholic cirrhosis in comparison with the healthy controls. Methods: The study population comprised 15 patients with non-alcoholic cirrhosis and 15 healthy subjects, undergoing 24-hour electrocardiogram (ECG), heart rate, and blood pressure monitoring. The mean QT interval, mean QTc, maximum and minimum QT, QT dispersion (QT disp), heart rate, and mean arterial blood pressure were measured for each person for 24 hours. Liver stiffness measurement (LSM) was performed by FibroScan® 502 machine (EchoSense, Paris, France, 5 MHz). The results were demonstrated as percentages and mean ± SD. P value ≤ 0.05 was considered significant. Results: Mean QTc was significantly higher in cirrhosis (438 ms) than healthy controls (401.7 ms) (P = 0.03). The mean heart rate was significantly different in cirrhotic patients (79.6 ± 2.9/bpm) compared to healthy controls (72.47 ± 2.0/bpm) (P = 0.05). Conclusions: In this study, QTc was prolonged and increased with the severity of cirrhosis, and its diurnal variation in cirrhosis was different from healthy subjects.

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