Highly sensitive, stable, and precise detection of dopamine with carbon dots/tyrosinase hybrid as fluorescent probe

RSC Advances ◽  
2014 ◽  
Vol 4 (87) ◽  
pp. 46437-46443 ◽  
Author(s):  
Hao Li ◽  
Juan Liu ◽  
Manman Yang ◽  
Weiqian Kong ◽  
Hui Huang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Carbon Dots ◽  
Low Cost ◽  
High Sensitivity ◽  
Highly Sensitive

The carbon dots/tyrosinase hybrid as a low-cost fluorescent probe for the detection of dopamine exhibits high sensitivity, stability, and precision.

Highly sensitive detection of Cr(vi) in groundwater by bimetallic NiFe nanoparticles

2017 ◽  
Vol 9 (6) ◽  
pp. 1031-1037 ◽  
Author(s):  
Jingtao Liu ◽  
Yu Ding ◽  
Lifei Ji ◽  
Xin Zhang ◽  
Fengchun Yang ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Hexavalent Chromium ◽  
Low Cost ◽  
High Sensitivity ◽  
Sensitive Detection ◽  
Toxic Heavy Metal ◽  
Metal Pollutants ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Heavy Metal Pollutants

Hexavalent chromium (Cr(vi)) is one of the most toxic heavy metal pollutants in groundwater, and thus the detection of Cr(vi) with high sensitivity, accuracy, and simplicity and low cost is of great importance.

scholarly journals Highly Sensitive Non-Enzymatic Detection of Glucose at MWCNT-CuBTC Composite Electrode

2020 ◽  
Vol 10 (23) ◽  
pp. 8419
Author(s):  
Adriana Remes ◽  
Florica Manea ◽  
Sorina Motoc (m. Ilies) ◽  
Anamaria Baciu ◽  
Elisabeta I. Szerb ◽  
...  
Keyword(s):  
Composite Electrode ◽  
Glucose Sensor ◽  
Low Cost ◽  
Multiwall Carbon Nanotubes ◽  
Linear Sweep Voltammetry ◽  
High Sensitivity ◽  
Differential Pulse ◽  
Roll Mill ◽  
Highly Sensitive ◽  
Enzymatic Detection

A novel electrochemical glucose sensor was developed, based on a multiwall carbon nanotubes (MWCNTs)-copper-1,3,5-benzenetricarboxylic acid (CuBTC)-epoxy composite electrode, named MWCNT-CuBTC. The electrode nanocomposite was prepared by a two-roll mill procedure and characterized morphostructurally by scanning electron microscopy (SEM). The CuBTC formed defined crystals with a wide size distribution, which were well dispersed and embedded in the MWCNTs. Its electrical conductivity was determined by four-point probe contact (DC) conductivity measurements. The electroactive surface area, determined using cyclic voltammetry (CV), was found to be 6.9 times higher than the geometrical one. The results of the electrochemical measurements using CV, linear sweep voltammetry (LSV), differential pulse voltammetry (DPV), chronoamperometry (CA) and multiple pulse amperometry (MPA) showed that the MWCNT-CuBTC composite electrode displayed high electrocatalytic activity toward the oxidation of glucose and, as a consequence, very high sensitivity. The best sensitivity of 14,949 µAmM−1cm−1 was reached using MPA at the potential value of 0.6 V/SCE, which was much higher in comparison with other copper-based electrodes reported in the literature. The good analytical performance, low cost and simple preparation method make this novel electrode material promising for the development of an effective glucose sensor.

Efficient one-pot synthesis of carbon dots as a fluorescent probe for the selective and sensitive detection of rifampicin based on the inner filter effect

2018 ◽  
Vol 10 (33) ◽  
pp. 4085-4093 ◽  
Author(s):  
Zhu Han ◽  
Yuwei Long ◽  
Shuang Pan ◽  
Hui Liu ◽  
Jidong Yang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Carbon Dots ◽  
Low Cost ◽  
Ammonium Thiocyanate ◽  
Inner Filter Effect ◽  
Ammonium Citrate ◽  
Blue Fluorescence ◽  
One Pot ◽  
One Pot Synthesis ◽  
Hydrothermal Approach

In this paper, carbon dots (CDs) emitting blue fluorescence were prepared using ammonium citrate and ammonium thiocyanate through a low-cost hydrothermal approach.

Amplification-Free DNA Detection Using a Microtip-Sensor Decorated With LNA Probes for Rapid TB Screening

2011 ◽  
Author(s):  
Shinnosuke Inoue ◽  
Woon-Hong Yeo ◽  
Jong-Hoon Kim ◽  
Jae-Hyun Chung ◽  
Kyong-Hoon Lee ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Staphylococcus Epidermidis ◽  
Genomic Dna ◽  
Bacterial Culture ◽  
Low Cost ◽  
Surrogate Marker ◽  
High Sensitivity ◽  
Diagnostic Methods ◽  
Nucleic Acid Amplification ◽  
Highly Sensitive

Tuberculosis (TB) is an epidemic affecting one-third of the world’s population, mostly in developing and low-resource settings. People having active pulmonary TB are considered highly infectious; therefore, it is critical to identify and treat these patients rapidly before spreading to others. However, the most reliable TB diagnostic methods of bacterial culture or nucleic acid amplification are time-consuming and expensive. The challenge of TB diagnosis lies in highly sensitive and specific screening with low cost. Here, we present an LNA-modified microtip-sensor, which is capable of selectively detecting low-abundance DNA from bacteria. When genomic DNA of Bacillus Calmette-Gue´rin (BCG, a surrogate marker of Mycobacterium bovis), and genomic DNA of Staphylococcus epidermidis (S. epi) are used, the microtip-sensor yields the detection limit of 1,000 copies/mL within 20 minutes. The high sensitivity and specificity approaching nucleic acid amplification methods can potentially overcome the current challenges for rapid TB screening.

Carbon dots from PEG for highly sensitive detection of levodopa

2015 ◽  
Vol 3 (11) ◽  
pp. 2378-2387 ◽  
Author(s):  
Hao Li ◽  
Juan Liu ◽  
Sijie Guo ◽  
Yalin Zhang ◽  
Hui Huang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Carbon Dots ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Fluorescent carbon dots (CDs)/tyrosinase hybrid as a fluorescent probe for efficient, fast and sensitive detection of levodopa.

scholarly journals Highly sensitive sensing of hydroquinone and catechol based on β-cyclodextrin-modified carbon dots

RSC Advances ◽  
2018 ◽  
Vol 8 (35) ◽  
pp. 19381-19388 ◽  
Author(s):  
Zhong-Yi Lin ◽  
Yuan-Chieh Kuo ◽  
Chih-Jui Chang ◽  
Yu-Syuan Lin ◽  
Tai-Chia Chiu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Efficient Method ◽  
Water Samples ◽  
Carbon Dots ◽  
Carbon Dot ◽  
Highly Sensitive

In the proposed study, an efficient method for a carbon dot@β-cyclodextrin (C-dot@β-CD)-based fluorescent probe was developed for the analyses of catechol (CC) and hydroquinone (HQ) at trace levels in water samples.

Low-cost and high sensitivity glucose sandwich detection using a plasmonic nanodisk metasurface

Nanoscale ◽  
2020 ◽  
Vol 12 (19) ◽  
pp. 10809-10815 ◽  
Author(s):  
Zhongwen Long ◽  
Yuzhang Liang ◽  
Lei Feng ◽  
Hui Zhang ◽  
Mingze Liu ◽  
...  
Keyword(s):  
Large Scale ◽  
Low Cost ◽  
High Sensitivity ◽  
Glucose Detection ◽  
Sensing Platform ◽  
Highly Sensitive

A low-cost, large scale plasmonic metasurface sensing platform shows enormous potential for highly sensitive and selective SERS-based glucose detection.

A PNA-Mediated Clamping PCR for Routine Detection of KRAS Mutations in Colorectal Carcinoma

2014 ◽  
Vol 29 (1) ◽  
pp. e55-e61 ◽  
Author(s):  
Francesca Messa ◽  
Federica Tonissi ◽  
Enrico Millo ◽  
Enrico Bracco ◽  
Silvana Ungari ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Low Cost ◽  
Screening Method ◽  
High Sensitivity ◽  
Kras Mutations ◽  
Laboratory Equipment ◽  
Highly Sensitive ◽  
Appropriate Therapy ◽  
Definition Of ◽  
Very High

The detection of somatic mutations in a tumor represents a valuable tool for tumor characterization and provides the clinicians with information for setting up the most appropriate therapy. KRAS mutations in codons 12 and 13 are important biomarkers routinely analyzed in the clinic for the management of anti-EGFR treatment in colorectal carcinoma (CRC). Here we report a sensitive and inexpensive assay for KRAS mutations based on a PNA-mediated PCR clamping. The assay displays very high sensitivity (0.7%) and specificity (96.7%) when compared to traditional sequencing (SS) and pyrosequencing (PS), two of the most commonly and routinely used methods employed today by diagnostic laboratories. Furthermore, the PNA assay requires only basic and low-cost laboratory equipment, in contrast with all the most recent PCR-based technologies, which are highly sensitive but also much more expensive. Finally, despite the PNA assay does not allow for the definition of specific mutations, it is the cheapest and easiest screening method to firstly stratify wild-type and mutated patients, information that is strictly necessary to clinicians for the management of CRC and anti-EGFR treatment.

scholarly journals Rapid Detection of Kaempferol Using Surface Molecularly Imprinted Mesoporous Molecular Sieves Embedded with Carbon Dots

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Yu He ◽  
Junping Wang ◽  
Shuo Wang
Keyword(s):  
Carbon Dots ◽  
Molecular Sieves ◽  
Low Cost ◽  
Synthesis Method ◽  
High Sensitivity ◽  
Mesoporous Molecular Sieves ◽  
One Pot ◽  
Molecularly Imprinted ◽  
Efficient Detection ◽  
Flavonoid Monomer

This work demonstrates rapid sensing of kaempferol using active sensing material synthesized using the one-pot surface-imprinting synthesis method. This sensor consisted of molecularly imprinted polymer (MIP) consisting of mesoporous molecular sieves (SBA-15) loaded with carbon dots (CDs). Fourier transform infrared (FT-IR) spectroscopy confirmed successful incorporation of CDs onto the surface of imprinted mesoporous molecular sieves. Ordered hexagonal arrays of CDs@SBA-15@MIP mesopore structure were confirmed with transmission electron microscopy. Fluorescence intensity of CDs@SBA-15@MIP composites linearly correlated with kaempferol content in the 0.05–2 mg/L range. Detection limit was 14 μg/L. MIPs were used for efficient detection of kaempferol in fruit and vegetable samples with recovery values from 80% to 112%. The method has high sensitivity, low cost, good selectivity, and many application potentials useful for research and development of flavonoid monomer presence in food.

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