Fe3O4@mSiO2 core–shell nanocomposite capped with disulfide gatekeepers for enzyme-sensitive controlled release of anti-cancer drugs

2015 ◽  
Vol 3 (6) ◽  
pp. 1010-1019 ◽  
Author(s):  
Chunyu Yang ◽  
Wei Guo ◽  
Liru Cui ◽  
Na An ◽  
Ting Zhang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Cancer Treatment ◽  
Silica Shell ◽  
Core Shell ◽  
Passive Targeting ◽  
Anti Cancer ◽  
Multifunctional Nanocarriers ◽  
Nanoparticle Core

Multifunctional nanocarriers based on the magnetic Fe3O4 nanoparticle core and bis-(3-carboxy-4-hydroxy phenyl) disulfide modified mesoporous silica shell were synthesized for cancer treatment through passive targeting and enzyme-sensitive drug release.

scholarly journals ATRP-based synthesis of a pH-sensitive amphiphilic block polymer and its self-assembled micelles with hollow mesoporous silica as DOX carriers for controlled drug release

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 29986-29996
Author(s):  
Xiuxiu Qi ◽  
Hongmei Yan ◽  
Yingxue Li
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Loading ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Core Shell ◽  
Assembly Process ◽  
Block Polymer ◽  
Hollow Mesoporous Silica

A pH-sensitive core–shell nanoparticle (HMS@C18@PSDMA-b-POEGMA) was developed via a self-assembly process as the carrier of anticancer drug doxorubicin (DOX) for drug loading and controlled release.

A NIR light-triggered drug delivery system using core–shell gold nanostars–mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG

2019 ◽  
Vol 55 (61) ◽  
pp. 9039-9042 ◽  
Author(s):  
Andy Hernández-Montoto ◽  
Mónica Gorbe ◽  
Antoni Llopis-Lorente ◽  
José Manuel Terrés ◽  
Roberto Montes ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
Silica Shell ◽  
Multiphoton Absorption ◽  
Core Shell ◽  
Gold Nanostars ◽  
Nir Light

Gold nanostars coated with a mesoporous silica shell and functionalised with PEG containing photolabile 2-nitrobenzyl moieties released doxorubicin after NIR light irradiation.

scholarly journals Photodynamic therapy-triggered on-demand drug release from ROS-responsive core-cross-linked micelles toward synergistic anti-cancer treatment

Nano Research ◽  
2019 ◽  
Vol 12 (5) ◽  
pp. 999-1008 ◽  
Author(s):  
Yongjuan Li ◽  
Jian Hu ◽  
Xun Liu ◽  
Yong Liu ◽  
Shixian Lv ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Drug Release ◽  
Cancer Treatment ◽  
On Demand ◽  
Anti Cancer

scholarly journals Mesoporous Silica Nanoparticles as Carriers for Therapeutic Biomolecules

Pharmaceutics ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 432 ◽  
Author(s):  
Rafael R. Castillo ◽  
Daniel Lozano ◽  
María Vallet-Regí
Keyword(s):  
Controlled Release ◽  
Mesoporous Silica ◽  
Nucleic Acids ◽  
Cancer Treatment ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Therapeutic Action ◽  
The Creation

The enormous versatility of mesoporous silica nanoparticles permits the creation of a large number of nanotherapeutic systems for the treatment of cancer and many other pathologies. In addition to the controlled release of small drugs, these materials allow a broad number of molecules of a very different nature and sizes. In this review, we focus on biogenic species with therapeutic abilities (proteins, peptides, nucleic acids, and glycans), as well as how nanotechnology, in particular silica-based materials, can help in establishing new and more efficient routes for their administration. Indeed, since the applicability of those combinations of mesoporous silica with bio(macro)molecules goes beyond cancer treatment, we address a classification based on the type of therapeutic action. Likewise, as illustrative content, we highlight the most typical issues and problems found in the preparation of those hybrid nanotherapeutic materials.

scholarly journals Tunable Ag@SiO2 core–shell nanocomposites for broad spectrum antibacterial applications

RSC Advances ◽  
2017 ◽  
Vol 7 (38) ◽  
pp. 23342-23347 ◽  
Author(s):  
Mark A. Isaacs ◽  
Lee J. Durndell ◽  
Anthony C. Hilton ◽  
Luca Olivi ◽  
Christopher M. A. Parlett ◽  
...  
Keyword(s):  
Controlled Release ◽  
Silver Nanoparticle ◽  
Broad Spectrum ◽  
Reverse Microemulsion ◽  
Core Shell ◽  
One Pot ◽  
Nanoparticle Core

Silica encapsulated silver nanoparticle core–shell nanocomposites of tunable dimensions were synthesised via a one-pot reverse microemulsion route to achieve controlled release of Ag+ ions for broad spectrum antibacterial application.

Core–shell noble-metal@zeolitic-imidazolate-framework nanocarriers with high cancer treatment efficiency in vitro

2019 ◽  
Vol 7 (7) ◽  
pp. 1050-1055 ◽  
Author(s):  
Liangcan He ◽  
Kanglei Pang ◽  
Wenwen Liu ◽  
Yue Tian ◽  
Lin Chang ◽  
...  
Keyword(s):  
Drug Release ◽  
Cancer Treatment ◽  
Drug Loading ◽  
Controlled Drug Release ◽  
Core Shell ◽  
Treatment Efficiency ◽  
Zeolitic Imidazolate Framework ◽  
High Drug ◽  
High Drug Loading

Core–shell Au@zeolitic-imidazolate-framework nanocarriers with high drug-loading, controlled drug release properties, and high cancer treatment efficiency.

scholarly journals Mesoporous-silica-coated palladium-nanocubes as recyclable nanocatalyst in C–C-coupling reaction – a green approach

RSC Advances ◽  
2020 ◽  
Vol 10 (44) ◽  
pp. 26504-26507
Author(s):  
Darius Rohleder ◽  
Philipp Vana
Keyword(s):  
Mesoporous Silica ◽  
Coupling Reaction ◽  
Product Yield ◽  
Silica Shell ◽  
Single Step ◽  
Core Shell ◽  
Coating Process ◽  
Coupling Reactions ◽  
Green Approach

A green approach: in a single-step coating process a mesoporous silica shell was tailored onto palladium-nanocubes. Along with a PEG-matrix this core–shell-nanocatalyst could be recovered after C–C-coupling reactions and reused without any significant decrease in product yield.

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