Inhibitory effects of selected dietary flavonoids on the formation of total heterocyclic amines and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in roast beef patties and in chemical models

2016 ◽  
Vol 7 (2) ◽  
pp. 1057-1066 ◽  
Author(s):  
Qin Zhu ◽  
Shuang Zhang ◽  
Mingfu Wang ◽  
Jie Chen ◽  
Zong-Ping Zheng

Dietary flavonoids effectively inhibit total HAs and PhIP formation in roast beef patties through scavenging of intermediates in formation pathways.

Author(s):  
Wei Wang ◽  
Xiaopu Ren ◽  
Yingjie Bao ◽  
Yuxia Zhu ◽  
Yawei Zhang ◽  
...  

Abstract2-amino-1-methyl-6-phenylimidazole[4,5-b]pyridine (PhIP) is one of the most abundant Heterocyclic amines (HAs) in meat products. Zanthoxylum bungeanum Maxim. leaf (ZML) extract has been shown to be rich in polyphenols, which are gaining increasing interest as efficient tools for inhibiting the formation of HAs. In the present work, the effects of ZML extract, major polyphenols, chlorogenic acid, hyperoside and quercitrin on the formation of PhIP in both roast beef patties and chemical model systems were investigated. UPLC-MS showed that ZML extract and those three polyphenols effectively inhibited PhIP formation. Additionally, GC-MS analysis showed that those three polyphenols significantly reduced the content of phenylacetaldehyde in the model systems, a key intermediate involved in PhIP formation. The subsequent UPLC-MS and TOF-MS/MS analysis found that hyperoside and quercitrin reacted with phenyacetaldehyde to form those four adducts, 8-C-(E-Phenylethenyl)hyperoside, 6-C-(E-Phenylethenyl)hyperoside, 8-C-(E-Phenylethenyl)quercitrin and 6-C-(E-Phenylethenyl)quercitrin, respectively. The results revealed that hyperoside and quercitrin could trap phenylacetaldehyde to form adducts, thereby, retarding the reaction of phenylacetaldehyde and creatinine, blocking the generation of PhIP.


2017 ◽  
Vol 8 (11) ◽  
pp. 3938-3950 ◽  
Author(s):  
Jing Chen ◽  
Zhiyong He ◽  
Fang Qin ◽  
Jie Chen ◽  
Dongsheng Cao ◽  
...  

The inhibitory effects of spices on free and protein-bound heterocyclic amines as analysed by UPLC-MS/MS and PCA.


Meat Science ◽  
2016 ◽  
Vol 117 ◽  
pp. 57-62 ◽  
Author(s):  
Kebba Sabally ◽  
Lekha Sleno ◽  
Julie-Anne Jauffrit ◽  
Michèle M. Iskandar ◽  
Stan Kubow

2017 ◽  
Vol 65 (22) ◽  
pp. 4493-4499 ◽  
Author(s):  
Jing Chen ◽  
Zhiyong He ◽  
Fang Qin ◽  
Jie Chen ◽  
Maomao Zeng

2020 ◽  
Vol 108 ◽  
pp. 106073 ◽  
Author(s):  
Nana Zhang ◽  
Yueliang Zhao ◽  
Daming Fan ◽  
Jianbo Xiao ◽  
Ka-Wing Cheng ◽  
...  

Foods ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1490
Author(s):  
Wei Wang ◽  
Lu Dong ◽  
Yan Zhang ◽  
Huaning Yu ◽  
Shuo Wang

In order to reduce the formation of heterocyclic amines in grilled beef patties without destroying their unique quality characteristics, the effects of different thermal processes, including charcoal grilling, infrared grilling, superheated steam roasting and microwave heating, on the production of heterocyclic amines in beef patties and grilling quality characteristics were systematically analyzed. The results showed that infrared grilling can significantly (p < 0.05) reduce the content of heterocyclic amines in grilled patties, and the combination of microwave heating or superheated steam roasting with infrared grilling could further reduce the content of heterocyclic amines, with a maximum reduction ratio of 44.48%. While subtle differences may exist in infrared grilled patties with/without superheated steam roasting or microwave heating, a slight change will not affect the overall quality characteristics of grilled patties. The combined thermal processing will not visually affect the color of the grilled patties. Correlation analysis and regression analysis showed that the reduction in heterocyclic amines caused by microwave heating and superheated steam roasting are related to the moisture content and lipid oxidation of grilled patties, respectively. Using combined thermal processes to reduce the formation of heterocyclic amines is advisable.


2018 ◽  
Vol 9 (6) ◽  
pp. 3126-3133 ◽  
Author(s):  
Ye Jiao ◽  
Yan Yan ◽  
Zhiyong He ◽  
Daming Gao ◽  
Fang Qin ◽  
...  

The profile of 18 heterocyclic amines from seven categories (including β-carbolines) in tea leaves during green and black tea processing procedures, as well as commercial tea products was screened by ultrahigh-performance liquid chromatography with tandem mass spectrometry.


2019 ◽  
Vol 10 (10) ◽  
pp. 6711-6719 ◽  
Author(s):  
Nanying Wang ◽  
Yanyang Wu ◽  
Xue Zhao ◽  
Bin Lai ◽  
Na Sun ◽  
...  

Fluorescent nanoparticles (FNs) from roast beef patties were characterized and used as nanocarriers for ferrous ions.


Sign in / Sign up

Export Citation Format

Share Document