Vascular- and hepato-protective effects of passion fruit seed extract containing piceatannol in chronic high-fat diet-fed rats

2016 ◽  
Vol 7 (9) ◽  
pp. 4075-4081 ◽  
Author(s):  
Akira Ishihata ◽  
Hiroko Maruki-Uchida ◽  
Nozomi Gotoh ◽  
Sumika Kanno ◽  
Yoshitaka Aso ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Chronic Administration ◽  
Seed Extract ◽  
Passion Fruit ◽  
Protective Effects ◽  
Fischer 344 Rats ◽  
High Fat ◽  
Fischer 344 ◽  
Cardiovascular Damage

The effects of chronic administration of piceatannol-enriched (9.5% w/w) passion fruit seed extract (PFSE) on the cardiovascular damage induced in a high-fat (HF) diet-fed model of Fischer 344 rats were evaluated.

Effect of Gender on the Response to a High Fat Diet in Aging Fischer 344 Rats

1989 ◽  
Vol 119 (10) ◽  
pp. 1472-1477 ◽  
Author(s):  
Roger B. McDonald ◽  
Kristin Carlson ◽  
Carolyn Day ◽  
Judith S. Stern ◽  
Barbara A. Horwitz
Keyword(s):  
High Fat Diet ◽  
Fischer 344 Rats ◽  
High Fat ◽  
Fischer 344

scholarly journals High-fat Diet Increases Phospholipid Peroxidation in the Liver of Mature Fischer 344 Rats

2017 ◽  
Vol 66 (6) ◽  
pp. 607-614
Author(s):  
Saki Hayasaka ◽  
Fumiko Kimura ◽  
Shunji Kato ◽  
Naoki Shimizu ◽  
Junya Ito ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Fischer 344 Rats ◽  
High Fat ◽  
Fischer 344 ◽  
Phospholipid Peroxidation

scholarly journals Fecal Microbial Enterotypes Differentially Respond to a High-fat Diet Based on Sex in Fischer-344 Rats

2021 ◽  
Vol 26 (4) ◽  
pp. 277-288
Author(s):  
Soo In Choi ◽  
Nayoung Kim ◽  
Ryoung Hee Nam ◽  
Ji Hyun Park ◽  
Heewon Nho ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Fischer 344 Rats ◽  
High Fat ◽  
Fischer 344

Fischer 344 rats are the same weight but are fatter than rats fed a high fat diet

1996 ◽  
Vol 16 (7) ◽  
pp. 1225-1237
Author(s):  
Rachel A. Schemmel ◽  
Krystyna Kras ◽  
Nelle Cotten ◽  
Kazuharu Suzuki ◽  
Bal K. Sharma ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Fischer 344 Rats ◽  
High Fat ◽  
Fischer 344

scholarly journals Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet

2021 ◽  
Author(s):  
Joe W. E. Moss ◽  
Jessica O Williams ◽  
Wijdan Al-Ahmadi ◽  
Victoria O'Morain ◽  
Yee-Hung Chan ◽  
...  
Keyword(s):  
Gene Expression ◽  
Risk Factors ◽  
Cardiovascular Disease ◽  
High Fat Diet ◽  
Inflammatory Disorder ◽  
Protective Effects ◽  
Unique Combination ◽  
Omega 3 ◽  
High Fat ◽  
Food Ingredients

Atherosclerosis, an inflammatory disorder of the vasculature and the underlying cause of cardiovascular disease, is responsible for one in three global deaths. Consumption of active food ingredients such as omega-3...

scholarly journals Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats

PLoS ONE ◽  
2018 ◽  
Vol 13 (8) ◽  
pp. e0201540 ◽  
Author(s):  
Roberta Budriesi ◽  
Fabio Vivarelli ◽  
Donatella Canistro ◽  
Rita Aldini ◽  
Clara Babot Marquillas ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Castanea Sativa ◽  
Bark Extract ◽  
Protective Effects ◽  
High Fat ◽  
Castanea Sativa Mill

scholarly journals Antiobesity and Hypolipidemic Activity of Moringa oleifera Leaves against High Fat Diet-Induced Obesity in Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Souravh Bais ◽  
Guru Sewak Singh ◽  
Ramica Sharma
Keyword(s):  
Body Weight ◽  
Body Temperature ◽  
Total Cholesterol ◽  
High Fat Diet ◽  
Moringa Oleifera ◽  
Chronic Administration ◽  
The Body ◽  
Atherogenic Index ◽  
High Fat ◽  
Diet Induced Obesity

In the present study, the methanolic extract of Moringa oleifera leaves (MEMOL) was evaluated for antiobesity activity in rats. The antiobesity potential of MEMOL was studied against high fat diet-induced obesity (HFD) in rats. In this study, chronic administration of HFD in rats produced hypercholesterolemia (116.2 ± 0.27 mg/dL), which led to an increase in the body weight (225 gr), total cholesterol, triglycerides (263.0 ± 4.69 mg/dL), and attenuation in the levels of HDL (34.51 ± 2.20 mg/dL) as well as changes in body temperature of animals. Treatment of obese rats with MEMOL for 49 days resulted in a significant (P<0.001) change in body weight, total cholesterol, triglycerides, and LDL level along with a significant (P<0.001) increase in body temperature as compared to the HFD-induced obesity. MEMOL treated rats also showed a significant decrease in the level of liver biomarkers, organ weight, and blood glucose level. Further, rats treated with MEMOL (200 mg and 400 mg/kg) show reduced atherogenic index (1.7 ± 0.6 and 0.87 ± 0.76). The results indicate that the rats treated with Moringa oleifera (MO) have significantly attenuated the body weight without any change in the feed intake and also elicited significant thermogenic effect and to act as hypolipidemic and thermogenic property in obesity related disorders.

scholarly journals Grape seed extract and delta tocotrienol alone and in combination ameliorates histopathological features in C57BL/J6 mouse fed high‐fat diet

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Shradha Sodhani ◽  
Shanil Juma ◽  
Parakat Vijayagopal ◽  
Chandan Prasad ◽  
Victorine Imrhan ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
High Fat ◽  
Histopathological Features

scholarly journals Protective Effects of Individual and Combined Low Dose Beta-Carotene and Metformin Treatments against High-Fat Diet-Induced Responses in Mice

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3607
Author(s):  
Bojan Stojnić ◽  
Alba Serrano ◽  
Lana Sušak ◽  
Andreu Palou ◽  
M. Luisa Bonet ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
High Fat Diet ◽  
Body Weight Gain ◽  
Beta Carotene ◽  
Protective Effects ◽  
High Fat ◽  
Cumulative Energy ◽  
Brown Adipose ◽  
Obesogenic Diet ◽  
Cumulative Energy Intake

Anti-obesity activity has been reported for beta-carotene (BC) supplementation at high doses and metformin (MET). We studied whether BC treatment at a closer to dietary dose and MET treatment at a lower than therapeutic dose are effective in ameliorating unwanted effects of an obesogenic diet and whether their combination is advantageous. Obesity-prone mice were challenged with a high-fat diet (HFD, 45% energy as fat) for 4 weeks while receiving a placebo or being treated orally with BC (3 mg/kg/day), MET (100 mg/kg/day), or their combination (BC+MET); a fifth group received a placebo and was kept on a normal-fat diet (10% energy as fat). HFD-induced increases in body weight gain and inguinal white adipose tissue (WAT) adipocyte size were attenuated maximally or selectively in the BC+MET group, in which a redistribution towards smaller adipocytes was noted. Cumulative energy intake was unaffected, yet results suggested increased systemic energy expenditure and brown adipose tissue activation in the treated groups. Unwanted effects of HFD on glucose control and insulin sensitivity were attenuated in the treated groups, especially BC and BC+MET, in which hepatic lipid content was also decreased. Transcriptional analyses suggested effects on skeletal muscle and WAT metabolism could contribute to better responses to the HFD, especially in the MET and BC+MET groups. The results support the benefits of the BC+MET cotreatment.

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