Synthesis of functionalized triple-doped zinc gallogermanate nanoparticles with superlong near-infrared persistent luminescence for long-term orally administrated bioimaging

Nanoscale ◽  
2016 ◽  
Vol 8 (32) ◽  
pp. 14965-14970 ◽  
Author(s):  
Yu-Jie Li ◽  
Xiu-Ping Yan
2016 ◽  
Vol 4 (48) ◽  
pp. 7845-7851 ◽  
Author(s):  
Junpeng Shi ◽  
Meng Sun ◽  
Xia Sun ◽  
Hongwu Zhang

Near-infrared persistent luminescence hollow mesoporous nanospheres have been synthesized via a template method. These nanospheres can be used as large capacity drug carriers and realize super long-term and high sensitivity tracking of drug delivery in deep tissue.


2017 ◽  
Vol 9 (47) ◽  
pp. 41181-41187 ◽  
Author(s):  
Xia-Hui Lin ◽  
Liang Song ◽  
Shan Chen ◽  
Xiao-Feng Chen ◽  
Jing-Jing Wei ◽  
...  

2019 ◽  
Author(s):  
Sharda S. Anroedh ◽  
Rohit M. Oemrawsingh ◽  
Robert-Jan van Geuns ◽  
Jin M. Cheng ◽  
Hector M. Garcia-Garcia ◽  
...  

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Liping Huang ◽  
Yiyi Zhang ◽  
Yanan Li ◽  
Fanling Meng ◽  
Hongyu Li ◽  
...  

AbstractThe highly immunosuppressive microenvironment after surgery has a crucial impact on the recurrence and metastasis in breast cancer patients. Programmable delivery of immunotherapy-involving combinations through a single drug delivery system is highly promising, yet greatly challenging, to reverse postoperative immunosuppression. Here, an injectable hierarchical gel matrix, composed of dual lipid gel (DLG) layers with different soybean phosphatidylcholine/glycerol dioleate mass ratios, was developed to achieve the time-programmed sequential delivery of combined cancer immunotherapy. The outer layer of the DLG matrix was thermally responsive and loaded with sorafenib-adsorbed graphene oxide (GO) nanoparticles. GO under manually controlled near-infrared irradiation generated mild heat and provoked the release of sorafenib first to reeducate tumor-associated macrophages (TAMs) and promote an immunogenic tumor microenvironment. The inner layer, loaded with anti-CD47 antibody (aCD47), could maintain the gel state for a much longer time, enabling the sustained release of aCD47 afterward to block the CD47-signal regulatory protein α (SIRPα) pathway for a long-term antitumor effect. In vivo studies on 4T1 tumor-bearing mouse model demonstrated that the DLG-based strategy efficiently prevented tumor recurrence and metastasis by locally reversing the immunosuppression and synergistically blocking the CD47-dependent immune escape, thereby boosting the systemic immune responses.


2016 ◽  
Vol 45 (4) ◽  
pp. 1364-1372 ◽  
Author(s):  
Jian Yang ◽  
Yuxue Liu ◽  
Duanting Yan ◽  
Hancheng Zhu ◽  
Chunguang Liu ◽  
...  

Novel ZGGO:Cr3+ nanoparticles with NIR super long afterglow were prepared via a hydrothermal method and a subsequent vacuum-annealing strategy.


2021 ◽  
Author(s):  
Tianpeng Liu ◽  
Zhiyuan Liu ◽  
Jiao Wu ◽  
Kang Zhang ◽  
Hongxiang An ◽  
...  

Transparent glass-ceramic is a highly attractive class of materials for photonic application. Transition metal ions are promising candidates for luminescence centers thanks to the sensitivity to the ligand ions of...


2016 ◽  
Vol 9 (6) ◽  
pp. 2445-2461 ◽  
Author(s):  
Akihiko Kuze ◽  
Hiroshi Suto ◽  
Kei Shiomi ◽  
Shuji Kawakami ◽  
Makoto Tanaka ◽  
...  

Abstract. A data set containing more than 6 years (February 2009 to present) of radiance spectra for carbon dioxide (CO2) and methane (CH4) observations has been acquired by the Greenhouse gases Observing SATellite (GOSAT, available at http://data.gosat.nies.go.jp/GosatUserInterfaceGateway/guig/GuigPage/open.do), nicknamed “Ibuki”, Thermal And Near infrared Sensor for carbon Observation Fourier Transform Spectrometer (TANSO-FTS). This paper provides updates on the performance of the satellite and TANSO-FTS sensor and describes important changes to the data product, which has recently been made available to users. With these changes the typical accuracy of retrieved column-averaged dry air mole fractions of CO2 and CH4 (XCO2 and XCH4, respectively) are 2 ppm or 0.5 % and 13 ppb or 0.7 %, respectively. Three major anomalies of the satellite system affecting TANSO-FTS are reported: a failure of one of the two solar paddles in May 2014, a switch to the secondary pointing system in January 2015, and most recently a cryocooler shutdown and restart in August 2015. The Level 1A (L1A) (raw interferogram) and the Level 1B (L1B) (radiance spectra) of version V201 described here have long-term uniform quality and provide consistent retrieval accuracy even after the satellite system anomalies. In addition, we discuss the unique observation abilities of GOSAT made possible by an agile pointing mechanism, which allows for optimization of global sampling patterns.


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