scholarly journals Probe for simultaneous membrane and nucleus labeling in living cells and in vivo bioimaging using a two-photon absorption water-soluble Zn(ii) terpyridine complex with a reduced π-conjugation system

2017 ◽  
Vol 8 (1) ◽  
pp. 142-149 ◽  
Author(s):  
Xiaohe Tian ◽  
Qiong Zhang ◽  
Mingzhu Zhang ◽  
Kajsa Uvdal ◽  
Qin Wang ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Living Cells ◽  
Water Soluble ◽  
Photon Absorption ◽  
Conjugation System ◽  
Two Photon Absorption ◽  
Two Photon ◽  
System P

A two-photon absorption water-soluble Zn(ii) probe for simultaneous membrane nucleus live cell imaging and its potential for blood-brain barrier staining.

A small-molecule with a large two-photon absorption cross-section serves as a membrane-permeable ribonucleic acid (RNA) probe for live cell imaging

2018 ◽  
Vol 42 (17) ◽  
pp. 14325-14331 ◽  
Author(s):  
Ruiqing Feng ◽  
Longlong Li ◽  
Bing Li ◽  
Jinhui Li ◽  
Dan Peng ◽  
...  
Keyword(s):  
Cross Section ◽  
Cross Sections ◽  
Live Cell Imaging ◽  
Plasma Membranes ◽  
Cell Imaging ◽  
Photon Absorption ◽  
Absorption Cross ◽  
High Permeability ◽  
Two Photon Absorption ◽  
Two Photon

DMI could light up the RNA of the nucleus and the cytoplasm in living systems, which not only exhibits larger two-photon absorption cross-sections (981 GM), but also displays high-permeability to plasma membranes of vigorous cells.

scholarly journals Small water-soluble pyrimidine hexafluorophosphate derivatives with high two-photon absorption activities in the near-IR region and their biological applications

RSC Advances ◽  
2017 ◽  
Vol 7 (32) ◽  
pp. 20068-20075 ◽  
Author(s):  
Qiong Zhang ◽  
Rongting Guan ◽  
Xiaohe Tian ◽  
Lei Luo ◽  
Hongping Zhou ◽  
...  
Keyword(s):  
Cross Section ◽  
Living Cells ◽  
Water Soluble ◽  
Photon Absorption ◽  
Biological Applications ◽  
Two Photon Absorption ◽  
Small Water ◽  
Two Photon ◽  
Near Ir ◽  
Fluorescence Methods

Two imidazole–pyrimidine hexafluorophosphate derivatives (6P and 10P) are synthesized. The 2PA cross-section values (σ) were obtained by Z-scan and two-photon excited fluorescence methods. 6P and 10P can be used to quantify and image organelles in living cells and tissues.

Water soluble fluorophore-carbazole–Au–DNA nanohybrid: enhanced two-photon absorption for living cell imaging application

RSC Advances ◽  
2015 ◽  
Vol 5 (114) ◽  
pp. 94446-94455 ◽  
Author(s):  
Shu-Juan Zhu ◽  
Lin Kong ◽  
Hui Wang ◽  
Yu-Peng Tian ◽  
Sheng-Li Li ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
Living Cell ◽  
Cell Imaging ◽  
Water Soluble ◽  
Photon Absorption ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Imaging Application ◽  
Living Cell Imaging

Water soluble L–Au–DNA nanohybrid exhibits enhanced 2PA properties that can widely and evenly uptake into the lysosome of HepG2 cells.

scholarly journals Rational design of asymmetric red fluorescent probes for live cell imaging with high AIE effects and large two-photon absorption cross sections using tunable terminal groups

2016 ◽  
Vol 7 (7) ◽  
pp. 4527-4536 ◽  
Author(s):  
Zheng-Feng Chang ◽  
Ling-Min Jing ◽  
Bin Chen ◽  
Mengshi Zhang ◽  
Xiaolei Cai ◽  
...  
Keyword(s):  
Cross Sections ◽  
Live Cell Imaging ◽  
Rational Design ◽  
Cell Imaging ◽  
Live Cell ◽  
Photon Absorption ◽  
Red Emission ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Donor Acceptor

Donor–acceptor π-conjugated aggregation-induced red emission materials for live cell imaging.

Synthesis, two-photon absorption and aggregation-induced emission properties of multi-branched triphenylamine derivatives based on diketopyrrolopyrrole for bioimaging

RSC Advances ◽  
2016 ◽  
Vol 6 (63) ◽  
pp. 58434-58442 ◽  
Author(s):  
Ji Yang ◽  
Haoqi Tan ◽  
Dongyu Li ◽  
Tao Jiang ◽  
Yuting Gao ◽  
...  
Keyword(s):  
Cell Imaging ◽  
Photon Absorption ◽  
Aggregation Induced Emission ◽  
Emission Properties ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Mouse Ear

Three new DPP-based multi-branched derivatives (YJ-1–3) with AIE and 2PA properties were synthesized. YJ-1 was applied for cell imaging and two-photon excited fluorescence in vivo imaging of mouse ear.

scholarly journals Polarity-active NIR probes with strong two-photon absorption and ultrahigh binding affinity of insulin amyloid fibrils

2021 ◽  
Author(s):  
Li Li ◽  
Zheng Lv ◽  
Zhongwei Man ◽  
Zhenzhen Xu ◽  
YuLing Wei ◽  
...  
Keyword(s):  
Neurodegenerative Diseases ◽  
Binding Affinity ◽  
Fluorescent Probes ◽  
Amyloid Fibrils ◽  
Photon Absorption ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Medical Diagnostic

Amyloid fibrils are associated with many neurodegenerative diseases. In-situ and in-vivo visualization of amyloid fibrils is important for medical diagnostic and requires fluorescent probes with both excitation and emission wavelengths in...

scholarly journals Two-Photon Time-Gated In Vivo Imaging of Dihydrolipoic-Acid-Decorated Gold Nanoclusters

Materials ◽  
2021 ◽  
Vol 14 (24) ◽  
pp. 7744
Author(s):  
Ye Tian ◽  
Ming Wei ◽  
Lijun Wang ◽  
Yuankai Hong ◽  
Dan Luo ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Gold Nanoclusters ◽  
Photon Absorption ◽  
Gold Nanocluster ◽  
Time Resolved ◽  
Dihydrolipoic Acid ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Time Resolved Imaging

Due to the unique advantages of two-photon technology and time-resolved imaging technology in the biomedical field, attention has been paid to them. Gold clusters possess excellent physicochemical properties and low biotoxicity, which make them greatly advantageous in biological imaging, especially for in vivo animal imaging. A gold nanocluster was coupled with dihydrolipoic acid to obtain a functionalized nanoprobe; the material displayed significant features, including a large two-photon absorption cross-section (up to 1.59 × 105 GM) and prolonged fluorescence lifetime (>300 ns). The two-photon and time-resolution techniques were used to perform cell imaging and in vivo imaging.

Syntheses and properties of acetylene-linked bis- and trisporphyrins toward two-photon photodynamic therapy

2007 ◽  
Vol 11 (06) ◽  
pp. 406-417 ◽  
Author(s):  
Yusuke Inaba ◽  
Kazuya Ogawa ◽  
Yoshiaki Kobuke
Keyword(s):  
Photodynamic Therapy ◽  
Cross Section ◽  
Sodium Salt ◽  
Absorption Cross Section ◽  
Water Soluble ◽  
Photon Absorption ◽  
Absorption Cross ◽  
Two Photon Absorption ◽  
Photon Irradiation ◽  
Two Photon

Acetylene-bridged bisporphyrins and trisporphyrins having branched bulky bis(carboxylethyl)methyl meso-substituents were synthesized. These compounds showed large effective two-photon absorption cross-section values at 890 nm measured by using a nanosecond Z-scan method. Sodium salt of hydrolyzed trisporphyrins showed broad and red-shifted Q-bands over 900 nm. Two-photon absorption cross-section values of water-soluble dimers in water were similar to, or slightly larger than, those of ester forms evaluated in toluene. Furthermore, the generation of singlet oxygen upon one-photon irradiation for dimers in water was confirmed.

scholarly journals Functional CdS-Au Nanocomposite for Efficient Photocatalytic, Photosensitizing, and Two-Photon Applications

Nanomaterials ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 715
Author(s):  
Katarzyna C. Nawrot ◽  
Dominika Wawrzyńczyk ◽  
Oleksii Bezkrovnyi ◽  
Leszek Kępiński ◽  
Bartłomiej Cichy ◽  
...  
Keyword(s):  
Light Exposure ◽  
Water Soluble ◽  
Photon Absorption ◽  
Photoluminescence Intensity ◽  
Oxidation Reactions ◽  
Au Nps ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Emission Lifetime ◽  
Efficient Charge

We demonstrate a low-temperature synthesis of hydrophilic, penicillamine-stabilized hybrid CdS-Au nanoparticles (NPs) utilizing different Au concentrations. The obtained hybrid nanomaterials exhibit photoluminescence quenching and emission lifetime reduction in comparison with their raw semiconductor CdS NPs counterparts. An increase of concentration of Au present at the surface of CdS leads to lower photoluminescence intensity and faster emission decays, suggesting more efficient charge separation when larger Au domains are present. For photocatalysis studies, we performed methylene blue (MB) absorption measurements under irradiation in the presence of CdS-Au NPs. After 1 h of light exposure, we observed the absorbance decrease to about 35% and 10% of the initial value for the CdS-5Au and CdS-7.5Au (the hybrid NPs obtained in a presence of 5.0 and 7.5 mM Au), respectively, which indicates MB reduction caused by electrons effectively separated from holes on metal surface. In further similar photocatalysis experiments, we measured bovine serum albumin (BSA) integrated photoluminescence intensity quenching in the presence of CdS-Au NPs, with a 50% decrease being obtained for CdS-2.5Au NPs and CdS-5Au NPs, with a faster response rate detected for the system prepared with a higher Au concentration. The results suggest hole-driven reactive oxygen species (ROS) production, causing BSA degeneration. Finally, we performed two-photon excited emission (TPEE) measurements for CdS-5Au NPs, obtaining their two-photon absorption (TPA) cross-section values up to 15.8 × 103 GM (Goeppert-Mayer units). We conclude that the obtained water-soluble CdS-Au NPs exhibit potential triple functionalities as photocatalysts for reduction and oxidation reactions as well as materials for two-photon absorption applications, so that they may be considered as future theranostics.

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