The influence of polyanion molecular weight on polyelectrolyte multilayers at surfaces: protein adsorption and protein–polysaccharide complexation/stripping on natural polysaccharide films on solid supports

2017 ◽  
Vol 19 (35) ◽  
pp. 23790-23801 ◽  
Author(s):  
Natalie L. Benbow ◽  
Jessie L. Webber ◽  
Sam Karpiniec ◽  
Marta Krasowska ◽  
James K. Ferri ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Protein Adsorption ◽  
Polyelectrolyte Multilayers ◽  
Solid Supports ◽  
Adsorption Studies ◽  
Natural Polysaccharide

Two different fucoidan polymers have been used to create substrates for protein adsorption studies.

scholarly journals Advances in Research on the Bioactivity of Alginate Oligosaccharides

Marine Drugs ◽  
2020 ◽  
Vol 18 (3) ◽  
pp. 144 ◽  
Author(s):  
Maochen Xing ◽  
Qi Cao ◽  
Yu Wang ◽  
Han Xiao ◽  
Jiarui Zhao ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Biological Activity ◽  
Theoretical Basis ◽  
Low Molecular Weight ◽  
Brown Seaweeds ◽  
Promote Cell Proliferation ◽  
Natural Polysaccharide ◽  
Alginate Oligosaccharides ◽  
Alginate Oligosaccharide ◽  
Alginate Degradation

Alginate is a natural polysaccharide present in various marine brown seaweeds. Alginate oligosaccharide (AOS) is a degradation product of alginate, which has received increasing attention due to its low molecular weight and promising biological activity. The wide-ranging biological activity of AOS is closely related to the diversity of their structures. AOS with a specific structure and distinct applications can be obtained by different methods of alginate degradation. This review focuses on recent advances in the biological activity of alginate and its derivatives, including their anti-tumor, anti-oxidative, immunoregulatory, anti-inflammatory, neuroprotective, antibacterial, hypolipidemic, antihypertensive, and hypoglycemic properties, as well as the ability to suppress obesity and promote cell proliferation and regulate plant growth. We hope that this review will provide theoretical basis and inspiration for the high-value research developments and utilization of AOS-related products.

In vitro protein adsorption studies on nevirapine nanosuspensions for HIV/AIDS chemotherapy

2011 ◽  
Vol 7 (3) ◽  
pp. 333-340 ◽  
Author(s):  
Ranjita Shegokar ◽  
Mirko Jansch ◽  
Kamalinder K. Singh ◽  
Rainer H. Müller
Keyword(s):  
Protein Adsorption ◽  
Adsorption Studies ◽  
Aids Chemotherapy ◽  
Vitro Protein ◽  
Hiv Aids

Experimental tensiometric protein adsorption studies

2010 ◽  
Vol 354 (1-3) ◽  
pp. 364-367 ◽  
Author(s):  
G. Dunne ◽  
N.D. McMillan ◽  
B. O’Rourke ◽  
D. Morrin ◽  
M. O’Neill ◽  
...  
Keyword(s):  
Protein Adsorption ◽  
Adsorption Studies

The effect of protein adsorption on the friction behavior of ultra-high molecular weight polyethylene

2006 ◽  
Vol 22 (2) ◽  
pp. 181-188 ◽  
Author(s):  
K. S. Kanaga Karuppiah ◽  
Sriram Sundararajan ◽  
Zhi-Hui Xu ◽  
Xiaodong Li
Keyword(s):  
Molecular Weight ◽  
Protein Adsorption ◽  
High Molecular Weight ◽  
Friction Behavior ◽  
Ultra High Molecular Weight

scholarly journals Bacterial Adhesion at Synthetic Surfaces

1999 ◽  
Vol 65 (11) ◽  
pp. 4995-5002 ◽  
Author(s):  
D. Cunliffe ◽  
C. A. Smart ◽  
C. Alexander ◽  
E. N. Vulfson
Keyword(s):  
Molecular Weight ◽  
Protein Adsorption ◽  
Bacterial Adhesion ◽  
Cell Attachment ◽  
Systematic Investigation ◽  
Bacterial Attachment ◽  
E Coli ◽  
Glass Substrates ◽  
Cell Adsorption

ABSTRACT A systematic investigation into the effect of surface chemistry on bacterial adhesion was carried out. In particular, a number of physicochemical factors important in defining the surface at the molecular level were assessed for their effect on the adhesion ofListeria monocytogenes, Salmonella typhimurium,Staphylococcus aureus, and Escherichia coli. The primary experiments involved the grafting of groups varying in hydrophilicity, hydrophobicity, chain length, and chemical functionality onto glass substrates such that the surfaces were homogeneous and densely packed with functional groups. All of the surfaces were found to be chemically well defined, and their measured surface energies varied from 15 to 41 mJ · m−2. Protein adsorption experiments were performed with3H-labelled bovine serum albumin and cytochromec prior to bacterial attachment studies. Hydrophilic uncharged surfaces showed the greatest resistance to protein adsorption; however, our studies also showed that the effectiveness of poly(ethyleneoxide) (PEO) polymers was not simply a result of its hydrophilicity and molecular weight alone. The adsorption of the two proteins approximately correlated with short-term cell adhesion, and bacterial attachment for L. monocytogenes and E. coli also correlated with the chemistry of the underlying substrate. However, for S. aureus and S. typhimurium a different pattern of attachment occurred, suggesting a dissimilar mechanism of cell attachment, although high-molecular-weight PEO was still the least-cell-adsorbing surface. The implications of this for in vivo attachment of cells suggest that hydrophilic passivating groups may be the best method for preventing cell adsorption to synthetic substrates provided they can be grafted uniformly and in sufficient density at the surface.

Effect of Molecular Weight on the Construction of Polyelectrolyte Multilayers:  Stripping versus Sticking

Langmuir ◽  
2003 ◽  
Vol 19 (6) ◽  
pp. 2491-2495 ◽  
Author(s):  
Zhijie Sui ◽  
David Salloum ◽  
Joseph B. Schlenoff
Keyword(s):  
Molecular Weight ◽  
Polyelectrolyte Multilayers

Physical and chemical immobilization of choline oxidase onto different porous solid supports: Adsorption studies

2016 ◽  
Vol 90 ◽  
pp. 76-82 ◽  
Author(s):  
Marieta L.C. Passos ◽  
David S.M. Ribeiro ◽  
João L.M. Santos ◽  
M.Lúcia M.F.S. Saraiva
Keyword(s):  
Porous Solid ◽  
Choline Oxidase ◽  
Solid Supports ◽  
Chemical Immobilization ◽  
Adsorption Studies ◽  
Physical And Chemical
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