Establishment of an immunofiltration strip for the detection of 17β-estradiol based on the photothermal effect of black phosphorescence

The Analyst ◽  
2019 ◽  
Vol 144 (22) ◽  
pp. 6647-6652 ◽  
Author(s):  
Lixia Lu ◽  
Minglu Wang ◽  
Dan Zhang ◽  
Hongyan Zhang

In this study, a novel immunofiltration strip method with temperature as the readout signal based on the photothermal effect of black phosphorus nanosheets was established. The temperature was monitored by a portable temperature sensor.

2018 ◽  
Author(s):  
Yingqian Wang ◽  
Xiaoxia Hu ◽  
Lingling Zhang ◽  
Chunli Zhu ◽  
Jie Wang ◽  
...  

Extracellular vesicles (EVs) are involved in the regulation of cell physiological activity and the reconstruction of extracellular environment. Matrix vesicles (MVs) are a type of EVs, and they participate in the regulation of cell mineralization. Herein, bioinspired MVs embedded with black phosphorus are functionalized with cell-specific aptamer (denoted as Apt-bioinspired MVs) for stimulating biomineralization. The aptamer can direct bioinspired MVs to targeted cells, and the increasing concentration of inorganic phosphate originated from the black phosphorus can facilitate cell biomineralization. The photothermal effect of the Apt-bioinspired MVs also positively affects mineralization. In addition, the Apt-bioinspired MVs display outstanding bone regeneration performance. Considering the excellent behavior of the Apt-bioinspired MVs for promoting biomineralization, our strategy provides a way of designing bionic tools for studying the mechanisms of biological processes and advancing the development of medical engineering.<br>


ACS Nano ◽  
2017 ◽  
Vol 11 (6) ◽  
pp. 6048-6056 ◽  
Author(s):  
Jinshui Miao ◽  
Bo Song ◽  
Qing Li ◽  
Le Cai ◽  
Suoming Zhang ◽  
...  

2018 ◽  
Author(s):  
Yingqian Wang ◽  
Xiaoxia Hu ◽  
Lingling Zhang ◽  
Chunli Zhu ◽  
Jie Wang ◽  
...  

Extracellular vesicles (EVs) are involved in the regulation of cell physiological activity and the reconstruction of extracellular environment. Matrix vesicles (MVs) are a type of EVs, and they participate in the regulation of cell mineralization. Herein, bioinspired MVs embedded with black phosphorus are functionalized with cell-specific aptamer (denoted as Apt-bioinspired MVs) for stimulating biomineralization. The aptamer can direct bioinspired MVs to targeted cells, and the increasing concentration of inorganic phosphate originated from the black phosphorus can facilitate cell biomineralization. The photothermal effect of the Apt-bioinspired MVs also positively affects mineralization. In addition, the Apt-bioinspired MVs display outstanding bone regeneration performance. Considering the excellent behavior of the Apt-bioinspired MVs for promoting biomineralization, our strategy provides a way of designing bionic tools for studying the mechanisms of biological processes and advancing the development of medical engineering.<br>


The Analyst ◽  
2019 ◽  
Vol 144 (2) ◽  
pp. 573-578 ◽  
Author(s):  
Min Jia ◽  
Jingjing Liu ◽  
Jinghua Zhang ◽  
Hongyan Zhang

A novel photothermal-immunofiltration strip which can simultaneously achieve sensitive detection and sterilization of Escherichia coli O157:H7 was designed.


Nanophotonics ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Shoushan Sang ◽  
Zhipeng Jiang ◽  
Ning Xie ◽  
Huaxin Rao ◽  
Kedan Liao ◽  
...  

Abstract Gastric cancer treatment remains a major challenge because of its aggressiveness and spread. In this study, we developed a hydrogel system for the treatment of gastric cancer, which can kill tumor cells through photothermal action and drug treatment. Based on the formation of Schiff base linkage, the OSA/AHA/BP/PTX hydrogel was prepared by mixing oxidized sodium alginate (OSA), aminated hyaluronic acid (AHA), black phosphorus (BP), and paclitaxel (PTX) under physiological conditions, which exhibited excellent photothermal effect and slow release ability PTX. Moreover, CCK-8 and live/dead fluorescent confirmed that OSA/AHA/BP/PTX hydrogel could obvious inhibition the proliferation of gastric cancer cells (SGC7901). More importantly, in vivo experiments further show that the prepared hydrogel can significantly improve the tumor treatment effect of tumor-bearing mice by inducing tumor cell apoptosis and inhibiting the proliferation of new tumor cells. Compared with chemotherapy alone, photothermal combined chemotherapy had a better antitumor effect. The results of this study indicate that the composite hydrogel with controlled release of paclitaxel can be used as a candidate material for cancer treatment.


Author(s):  
Jinxiu Cao ◽  
Junyang Qi ◽  
Xun Lin ◽  
Yue Xiong ◽  
Fumei He ◽  
...  

As a biodegradable material, black phosphorus (BP) has been considered as an efficient agent for cancer photothermal therapy. However, its systemic delivery faces several hurdles, including rapid degradation in blood circulation, quick clearance by the immune system, and low delivery sufficiency to the tumor site. Here, we developed a biomimetic nanoparticle platform for in vivo tumor-targeted delivery of BP nanosheets (BP NSs). Through a biomimetic strategy, BP NSs were utilized to coordinate with the active species of oxaliplatin (1,2-diaminocyclohexane) platinum (II) (DACHPt) complexions, and the nanoparticles were further camouflaged with mesenchymal stem cell (MSC)–derived membranes. We showed that the incorporation of DACHPt not only decelerated the BP degradation but also enhanced the antitumor effect by combining the photothermal effect with chemotoxicity. Furthermore, MSC membrane coating increased the stability, dispersibility, and tumor-targeting properties of BP/DACHPt, significantly improving the antitumor efficacy. In short, our work not only provided a new strategy for in vivo tumor-targeted delivery of BP NSs but also obtained an enhanced antitumor effect by combining photothermal therapy with chemotherapy.


Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 984
Author(s):  
Weiwei Yang ◽  
Ying Liu ◽  
Jie Wei ◽  
Xueli Li ◽  
Nianhua Li ◽  
...  

Fire-protection coatings with a self-monitoring ability play a critical role in safety and security. An intelligent fire-protection coating can protect humans from personal and property damage. In this work, we report the fabrication of a low-cost and facile intelligent fire coating based on a composite of ammonium polyphosphate and epoxy (APP/EP). The composite was processed using laser scribing, which led to a laser-induced graphene (LIG) layer on the APP/EP surface via a photothermal effect. The C–O, C=O, P–O, and N−C bonds in the flame-retardant APP/EP composite were broken during the laser scribing, while the remaining carbon atoms recombined to generate the graphene layer. A proof-of-concept was achieved by demonstrating the use of LIG in supercapacitors, as a temperature sensor, and as a hazard detection device based on the shape memory effect of the APP/EP composite. The intelligent flame protection coating had a high flame retardancy, which increased the time to ignition (TTI) from 21 s to 57 s, and the limiting oxygen index (LOI) value increased to 37%. The total amount of heat and smoke released during combustion was effectively suppressed by ≈ 71.1% and ≈ 74.1%, respectively. The maximum mass-specific supercapacitance could reach 245.6 F·g−1. The additional LIG layer enables applications of the device as a LIG-APP/EP temperature sensor and allows for monitoring of the deformation according to its shape memory effect. The direct laser scribing of graphene from APP/EP in an air atmosphere provides a convenient and practical approach for the fabrication of flame-retardant electronics.


Sign in / Sign up

Export Citation Format

Share Document