Fermented carrot juice attenuates type 2 diabetes by mediating gut microbiota in rats

2019 ◽  
Vol 10 (5) ◽  
pp. 2935-2946 ◽  
Author(s):  
Rongkang Hu ◽  
Feng Zeng ◽  
Linxiu Wu ◽  
Xuzhi Wan ◽  
Yongfang Chen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Fatty Acid ◽  
Gut Microbiota ◽  
Short Chain Fatty Acid ◽  
Lactobacillus Rhamnosus ◽  
Chain Fatty Acid ◽  
Carrot Juice ◽  
Protein Expressions ◽  
Free Phenolics

Carrot juice fermented with Lactobacillus rhamnosus GG, enriched with free phenolics, organic acids and short-chain fatty acid, has the potential to ameliorate type 2 diabetes, in part through modulating specific gut microbiota and regulating the mRNA and protein expressions levels involved in glucose metabolism.

Sa1984 Influence of Intestinal Microbiome and Short Chain Fatty Acid on Metabolism in Type 2 Diabetes Patients

2016 ◽  
Vol 150 (4) ◽  
pp. S424
Author(s):  
Makoto Sasaki ◽  
Tomoya Sugiyama ◽  
Seiji Noguchi ◽  
Hiroki Kitahora ◽  
Akihiro Shimozato ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Fatty Acid ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Intestinal Microbiome ◽  
Diabetes Patients

Prospect for type 2 diabetes mellitus in the combination of exercise and synbiotic: a perspective

2021 ◽  
Vol 17 ◽  
Author(s):  
Luthfia Dewi ◽  
Ali Rosidi ◽  
Etika Ratna Noer ◽  
Annisa Ayuningtyas
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gut Microbiota ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Glucose Regulation ◽  
Improve Insulin Sensitivity ◽  
Microbiome Diversity

: Change in gut microbiome diversity (the so-called dysbiosis) is correlated with insulin resistance conditions. Exercise is typically one of the first management for people with type 2 diabetes mellitus (T2DM), which is generally well-known for improved glucose regulation. The new design of prebiotic and probiotic, like synbiotic form, to target specific diseases is needed for additional studies. While the effectiveness of exercise and the combination of exercise and synbiotic prescription seems promising, this review discusses the possibility of these agents to increase the diversity of gut microbiota and therefore could enhance short-chain fatty acid (SCFA). In particular, the interaction of synbiotic towards gut microbiota, the mechanism of exercise in improving gut microbiota, and the prospect of the synergistic effect of the combination of synbiotic and exercise to improve insulin sensitivity is addressed.

Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity

Gene ◽  
2014 ◽  
Vol 537 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Marlene Remely ◽  
Eva Aumueller ◽  
Christine Merold ◽  
Simone Dworzak ◽  
Berit Hippe ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Fatty Acid ◽  
Epigenetic Regulation ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Acid Producing Bacteria ◽  
Diabetes And Obesity

Wheat cell walls and constituent polysaccharides induce similar microbiota profiles upon in vitro fermentation despite different short chain fatty acid end-product levels.

2021 ◽  
Author(s):  
Shiyi Lu ◽  
Deirdre Mikkelsen ◽  
Hong Yao ◽  
Barbara Williams ◽  
Bernadine Flanagan ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Gut Microbiota ◽  
Plant Cell ◽  
Cell Walls ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Plant Cell Walls ◽  
Human Gut ◽  
In Vitro Fermentation

Plant cell walls as well as their component polysaccharides in foods can be utilized to alter and maintain a beneficial human gut microbiota, but it is not known whether the...

scholarly journals Comparative analysis of the gut microbiota of mice fed a diet supplemented with raw and cooked beef loin powder

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hye-Jin Kim ◽  
Dongwook Kim ◽  
Kwan-Woo Kim ◽  
Sang-Hoon Lee ◽  
Aera Jang
Keyword(s):  
Fatty Acid ◽  
Comparative Analysis ◽  
Gut Microbiota ◽  
Ribosomal Rna ◽  
Relative Abundance ◽  
Short Chain Fatty Acid ◽  
Dietary Supplementation ◽  
Acid Synthesis ◽  
Chain Fatty Acid ◽  
Increasing Trend

AbstractWe used 16S ribosomal RNA sequencing to evaluate changes in the gut microbiota of mice fed a diet supplemented with either raw or cooked beef loin powder for 9 weeks. Male BALB/c mice (n = 60) were randomly allocated to five groups: mice fed AIN-93G chow (CON), chow containing 5% (5RB) and 10% (10RB) raw beef loin powder, and chow containing 5% (5CB) and 10% (10CB) cooked beef loin powder. Dietary supplementation with both RB and CB increased the relative abundance of Clostridiales compared to the CON diet (p < 0.05). Mice fed 10RB showed a significantly higher relative abundance of Firmicutes (p = 0.018) and Lactobacillus (p = 0.001) than CON mice, and the ratio of Firmicutes/Bacteroidetes showed an increasing trend in the 10RB mice (p > 0.05). Mice fed 10CB showed a higher abundance of Peptostreptococcaceae and a lower abundance of Desulfovibrionaceae compared with the CON mice (p < 0.05). Genes for glycan biosynthesis, which result in short-chain fatty acid synthesis, were enriched in the CB mice compared to the RB mice, which was correlated to a high abundance of Bacteroides. Overall, dietary RB and CB changed the gut microbiota of mice (p < 0.05).

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