Track-walking molecular motors: a new generation beyond bridge-burning designs

Nanoscale ◽  
2019 ◽  
Vol 11 (19) ◽  
pp. 9240-9263 ◽  
Author(s):  
Zhisong Wang ◽  
Ruizheng Hou ◽  
Iong Ying Loh
Keyword(s):  
Chemical Synthesis ◽  
Molecular Motors ◽  
Technological Capability ◽  
Assembly Lines ◽  
Bottom Up ◽  
The Core ◽  
New Generation ◽  
Molecular Robots ◽  
Nanoscale Assembly

Track-walking molecular motors are the core bottom-up mechanism for nanometre-resolved translational movements – a fundamental technological capability at the root of numerous applications ranging from nanoscale assembly lines and chemical synthesis to molecular robots and shape-changing materials.

Green Synthesis of 2-thioxothiazolidin-4-one Derivatives in Deep Eutectic Solvents via Knoevenagel Condensation

2022 ◽  
Vol 19 ◽  
Author(s):  
Melita Lončarić ◽  
MAJA MOLNAR
Keyword(s):  
Chemical Synthesis ◽  
Green Synthesis ◽  
Environmental Pollution ◽  
Knoevenagel Condensation ◽  
Choline Chloride ◽  
Deep Eutectic Solvents ◽  
Model Reaction ◽  
Methods And Techniques ◽  
New Generation ◽  
Toxic Organic Solvents

Abstract: Recently, more and more researchers are resorting to green methods and techniques to avoid environmental pollution. Accordingly, many researchers have been working on the development of new green synthetic procedures trying to avoid the use of toxic organic solvents. A sustainable concept of green and environmentally friendly solvents in chemical synthesis nowadays encompasses a relatively new generation of solvents called deep eutectic solvents (DESs). DESs often have a dual role in the synthesis, acting as both, solvents and catalysts. In this study, DESs are used in the Knoevenagel synthesis of rhodanine derivatives, with no addition of conventional catalysts. A model reaction of rhodanine and salicylaldehyde was performed in 20 different DESs at 80 °C, in order to find the best solvent, which was further used for the synthesis of the series of desired compounds. A series of rhodanines was synthesized in choline chloride: acetamide (ChCl:acetamide) DES with good to excellent yields (51.4 – 99.7 %).

scholarly journals Switching perception of musical meters by listening to different acoustic cues of biphasic sound stimulus.

2020 ◽  
Author(s):  
Sotaro Kondoh ◽  
Kazuo Okanoya ◽  
Ryosuke O Tachibana
Keyword(s):  
Music Perception ◽  
Sound Stimulus ◽  
Acoustic Cues ◽  
Point Scale ◽  
Top Down ◽  
Bottom Up ◽  
The Core ◽  
Entire Structure ◽  
Core Features

Meter is one of the core features of music perception. It is the cognitive grouping of regular sound sequences, typically for every 2, 3, or 4 beats. Previous studies have suggested that one can not only passively perceive the meter from acoustic cues such as loudness, pitch, and duration of sound elements, but also actively perceive it by paying attention to isochronous sound events without any acoustic cues. Studying the interaction of top-down and bottom-up processing in meter perception leads to understanding the cognitive system’s ability to perceive the entire structure of music. The present study aimed to demonstrate that meter perception requires the top-down process (which maintains and switches attention between cues) as well as the bottom-up process for discriminating acoustic cues. We created a “biphasic” sound stimulus, which consists of successive tone sequences designed to provide cues for both the triple and quadruple meters in different sound attributes, frequency, and duration, and measured how participants perceived meters from the stimulus in a five-point scale (ranged from “strongly triple” to “strongly quadruple”). Participants were asked to focus on differences in frequency and duration. We found that well-trained participants perceived different meters by switching their attention to specific cues, while untrained participants did not. This result provides evidence for the idea that meter perception involves the interaction between top-down and bottom-up processes, which training can facilitate.

scholarly journals Switching perception of musical meters by listening to different acoustic cues of biphasic sound stimulus

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256712
Author(s):  
Sotaro Kondoh ◽  
Kazuo Okanoya ◽  
Ryosuke O. Tachibana
Keyword(s):  
Music Perception ◽  
Sound Stimulus ◽  
Acoustic Cues ◽  
Point Scale ◽  
Top Down ◽  
Bottom Up ◽  
The Core ◽  
Entire Structure ◽  
Core Features

Meter is one of the core features of music perception. It is the cognitive grouping of regular sound sequences, typically for every 2, 3, or 4 beats. Previous studies have suggested that one can not only passively perceive the meter from acoustic cues such as loudness, pitch, and duration of sound elements, but also actively perceive it by paying attention to isochronous sound events without any acoustic cues. Studying the interaction of top-down and bottom-up processing in meter perception leads to understanding the cognitive system’s ability to perceive the entire structure of music. The present study aimed to demonstrate that meter perception requires the top-down process (which maintains and switches attention between cues) as well as the bottom-up process for discriminating acoustic cues. We created a “biphasic” sound stimulus, which consists of successive tone sequences designed to provide cues for both the triple and quadruple meters in different sound attributes, frequency, and duration. Participants were asked to focus on either frequency or duration of the stimulus, and to answer how they perceived meters on a five-point scale (ranged from “strongly triple” to “strongly quadruple”). As a result, we found that participants perceived different meters by switching their attention to specific cues. This result adds evidence to the idea that meter perception involves the interaction between top-down and bottom-up processes.

scholarly journals Design and implementation of a distributed data acquisition function architecture based on DOA/Handle technology

2021 ◽  
Vol 336 ◽  
pp. 05018
Author(s):  
Hongfei Li ◽  
Yong Kong ◽  
Xueli Wang
Keyword(s):  
Data Acquisition ◽  
Data Security ◽  
Internet Technology ◽  
Distributed Data ◽  
Digital Object ◽  
Security Governance ◽  
The Core ◽  
Industrial Internet ◽  
Internet Environment ◽  
New Generation

With the development of new generation Internet technology, Digital Object Architecture (DOA)/Handle system plays an important role in industrial system. The development and technical characteristics of DOA/Handle technology is studied in this paper. Then function architecture of distributed data acquisition system based on DOA/Handle technology is proposed. Through the detailed design of the functions and characteristics of the architecture, the core functions such as distributed data acquisition, distributed data management, data security sharing, and data security governance are realized in the industrial Internet environment. At the end of the paper, the typical scenarios of this architecture are summarized, and a prospect of the application prospect of DOA/Handle technology is introduced.

scholarly journals MEMBANGUN KARAKTER BANGSA MELALUI PEMBELAJARAN MATEMATIKA KURIKULUM 2013

2013 ◽  
Vol 14 (2) ◽  
pp. 73-80
Author(s):  
Wahyudin Wahyudin
Keyword(s):  
Problem Solving ◽  
Child Development ◽  
Character Education ◽  
Teaching Practice ◽  
Successful Implementation ◽  
Knowledge And Skills ◽  
The Core ◽  
Self Development ◽  
Points Of View ◽  
New Generation

The development of the character education still becomes the controversy among the educators, either from the theoretical or philosophical points of view. Actually, the core of the character education is not only viewed from philosophical difference, pedagogical ideology, or politics, but focused on the child development. Curriculum 2013 seeks to provide a problem-solving on the cultural matters and the national characters by integrating the characters / values /attitudes into the lessons, self-development, and the culture of the school. It is expected that a new generation of nation is developed in attitudes, knowledge, and skills. It has been clear that teachers thought, beliefs, and choices will influence their teaching practice. Therefore, it is necessary to build the views, beliefs, and positive selection within the teachers mind for the successful implementation of Curriculum 2013.   Perkembangan pendidikan karakter sampai sejauh ini masih penuh dengan kontroversi yang terutama berakar dalam berbagai perbedaan teoretis dan filosofis, meski sebenarnya inti dari pendidikan karakter tidak pada perbedaan filosofis, ideologi pedagogis, politik, dan sebagainya, melainkan tentang perkembangan anak. Kurikulum 2013 berupaya memberikan pemecahan persoalan budaya dan karakter bangsa dengan cara mengintegrasikan karakter/nilai/sikap ke dalam mata pelajaran, pengembangan diri, dan budaya sekolah, dengan harapan terbentuknya generasi baru bangsa yang utuh dalam sikap, pengetahuan, dan keterampilan. Dengan menyadari bahwa pandangan, keyakinan, dan pilihan para guru akan berpengaruh pada praktek pembelajaran, maka perlu dibangun pandangan, keyakinan, dan pilihan yang positif dalam diri para guru demi keberhasilan implementasi Kurikulum 2013.

scholarly journals MEs in Nano-Medicine

2012 ◽  
Vol 134 (06) ◽  
pp. 36-41
Author(s):  
Guy M. Genin ◽  
Ram V. Devireddy
Keyword(s):  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Osteogenesis Imperfecta ◽  
High Efficiency ◽  
Medical Diagnostics ◽  
Imperial College ◽  
Current Generation ◽  
The Core ◽  
Nano Medicine ◽  
New Generation

This article reviews the use of mechanical engineering techniques in the field of nano-engineered medicines. Nano-engineered solutions now exist for a range of medical diagnostics, therapeutics, and imaging, and are at the core of many of the current generation of regenerative medicine and tissue engineering strategies. Nanoparticles can be developed to absorb energy with high efficiency from photons of certain frequency ranges. The ability to understand specific diseases such as osteogenesis imperfecta based upon such fundamental analyses has been demonstrated by ASME member Sandra Shefelbine of Imperial College London in collaboration with the Buehler group. The tools of nanotechnology have enabled mechanical engineers to engineer the beginnings of an entirely new generation of cures and therapies, and this article has discussed just a sample. In order to serve as a forum for discussion of these advances ASME is recommissioning the Journal of Nanotechnology in Engineering and Medicine.

Local Infrastructures for Peace

2021 ◽  
pp. 626-640
Author(s):  
Andries Odendaal
Keyword(s):  
Top Down ◽  
Bottom Up ◽  
Local Agency ◽  
The Core ◽  
Past Experiences ◽  
The Way

The way “the local” had been interpreted led to contrasting top-down or bottom-up understandings of local infrastructures for peace. This chapter presents a reinterpretation of the relevance of infrastructures for peace from a practitioner’s perspective, considering past experiences and current theoretical debates. It argues for an appreciation of the complex, interlinked nature of global, national, and local conflicts and the necessity of flexible yet sustained and productive dialogue platforms at the points of frictional interactions at and between all these levels. The capacity to initiate and support such dialogue platforms where, crucially, local agency is respected is at the core of the approach that became known as “infrastructures for peace.”

Preparation and Structure of Oxide and Reduced Nd(Fe1-xCox)B Nanoparticles

2020 ◽  
Vol 312 ◽  
pp. 288-294
Author(s):  
Ghader Ahmadpour ◽  
Aleksey Yu. Samardak ◽  
Farzad Nasirpouri ◽  
A.S. Samardak ◽  
Alexey V. Ognev
Keyword(s):  
Chemical Synthesis ◽  
Permanent Magnets ◽  
Sol Gel ◽  
Synthesis Process ◽  
Bottom Up ◽  
Gel Method ◽  
Sol Gel Method ◽  
Co Concentrations

Nanoparticles of Nd(Fe1-xCox)B with Co concentrations ranging from x = 0 to 0.5 were prepared using a modified Pechini-type sol-gel method. We have shown the influence of Co on the morphology and size of nanoparticles, as well as on elements distribution in nanostructures. It was found that nanoparticles with increased content of Fe and Co were formed during the synthesis process. There was an interdiffusion of Nd and Fe, both after oxidation and after reduction. This study helped to define promising “bottom-up” approaches for the fabrication of nanomaterials for the advanced Nd(Fe1-xCox)B permanent magnets by chemical synthesis.

scholarly journals Some challenges to manufacturing engineer education process at TU – Varna

2019 ◽  
Vol 299 ◽  
pp. 05006 ◽  
Author(s):  
Pavlina Toteva–Lyutova ◽  
Krasimira Koleva ◽  
Nadezhda Tsoneva
Keyword(s):  
Intellectual Capital ◽  
Design Education ◽  
Developed Countries ◽  
Technological Infrastructure ◽  
The Core ◽  
Technology Applications ◽  
Engineer Education ◽  
New Generation ◽  
Product Specifications ◽  
Education Process

Today's economic development is dynamic, closely connected with high technology applications, a growth in intellectual capital and widespread innovations. Most economically developed countries realise the need to create new solutions to present or upcoming problems. Creating a modern innovative, educational, scientific and technological infrastructure becomes an important issue. The 21st century sets new challenges to future engineering specialists. The paper analyses the currently demanded engineering competencies and modern requirements to engineer training in order to prepare reliable specialists for the labour market. The purpose of this paper is to present a brief analysis of the syllabi and the content of the separate disciplines which ensure qualified student education. An attempt to include geometrical dimensioning and tolerance in design education at TU – Varna was reported in this paper, standards which are the core of geometrical product specifications inevitably required in the age of globalization of industry. The paper gives some hints how to teach efficiently the new generation of GPS standards at the mechanical engineering faculty.

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