A near-infrared light-controlled, ultrasensitive one-step photoelectrochemical detection of dual cell apoptosis indicators in living cancer cells

2020 ◽  
Vol 56 (60) ◽  
pp. 8488-8491
Author(s):  
Ying-Ning Zheng ◽  
Cheng-Yi Xiong ◽  
Ying Zhuo ◽  
Ya-Qin Chai ◽  
Wen-Bin Liang ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Cell Apoptosis ◽  
Adenosine Triphosphatase ◽  
Near Infrared ◽  
Infrared Light ◽  
Sodium Potassium ◽  
Near Infrared Light ◽  
Nir Light ◽  
One Step

The proposed near-infrared (NIR) light-controlled, one-step photoelectrochemical (PEC) strategy could simultaneously detect cell apoptosis indicators, phosphatidylserine (Pho) and sodium potassium adenosine triphosphatase (Sat), on living cancer cells.

Detection of residual varicose veins with near infrared light in the early period after varicose surgery and near infrared light assisted sclerotherapy

Vascular ◽  
2021 ◽  
pp. 170853812110514
Author(s):  
Nail Kahraman ◽  
Gündüz Yümün ◽  
Deniz Demir ◽  
Kadir K Özsin ◽  
Sadık A Sünbül ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Saphenous Vein ◽  
Venous Insufficiency ◽  
Near Infrared ◽  
Varicose Veins ◽  
Infrared Light ◽  
Foam Sclerotherapy ◽  
Near Infrared Light ◽  
Nir Light ◽  
Male Patients

Objectives Varicose veins that cannot be seen with the naked eye can be easily detected with Near Infrared (NIR) light. With a minimally invasive procedure performed with NIR light guided, the need for reoperation is reduced, while optimal treatment of venous insufficiency and symptoms is provided. In this study, the detection of residual varicose veins after varicose vein surgery using NIR light and the results of treatment of sclerotherapy were investigated. Methods In this retrospective study, treatment and clinical outcomes of patients’ who underwent NIR light-guided foam sclerotherapy for Clinical-Etiology-Anatomy-Pathophysiology (CEAP) (C1, C2) stage residual varicose veins after surgical varicose treatment between 2014 and 2017 were examined. Data of patients who underwent foam sclerotherapy with NIR light were collected and analyzed. Results A total of 151 patients and 171 lower extremity varicose veins were treated with surgery. 55 (35.7%) of the patients were male, and 96 (62.3%) were female. Their age ranges from 20 to 64, with an average age of 45.38. 4 (2.6%) of the patients had phlebectomy. 137 of patients (90.7%) had ligation of perforated veins, phlebectomy, and great saphenous vein (GSV) stripping, 10 of patients (6.6%) had GSV stripping, perforating vein ligation, phlebectomy, and small saphenous vein (SSV) surgery. No residual leakage was observed in the controls of GSV, SSV, and perforating veins by duplex ultrasonography (DUS). In the first month after varicose surgery, an average of 1.64 ± 1.05 sessions of sclerotherapy was applied to patients with CEAP C1, C2 stage residual varicose veins. 70 patients had one session of sclerotherapy, 37 patients had two sessions of sclerotherapy, 20 patients had three sessions of sclerotherapy, and 11 patients had four sessions of sclerotherapy administrated. The need for complementary therapy was required for all female patients; 13 of the male patients did not require complementary sclerotherapy. While single-session sclerotherapy was applied to most male patients (32 (58.18%), 10 (18.18%) patients received two sclerotherapy sessions. After completing sclerotherapy, 7 (4.63%) patients had superficial venous thrombosis, and 13 (8.60%) patients had hyperpigmentation. Conclusion Surgical treatment is a safe and effective technique in venous insufficiency. Nevertheless, residual varicose veins may remain, and these can be detected noninvasively with NIR light. Foam sclerotherapy with NIR light is a minimally invasive and safe treatment method for small residual varicose veins after the operation. We think that sclerotherapy with NIR light as a complementary treatment is a practical, reliable, and demanding treatment for clinical improvement, especially in female patients.

Near-infrared light-triggered drug release from UV-responsive diblock copolymer-coated upconversion nanoparticles with high monodispersity

2018 ◽  
Vol 6 (21) ◽  
pp. 3531-3540 ◽  
Author(s):  
Jun Xiang ◽  
Xia Tong ◽  
Feng Shi ◽  
Qiang Yan ◽  
Bing Yu ◽  
...  
Keyword(s):  
Drug Release ◽  
Diblock Copolymer ◽  
Near Infrared ◽  
Controlled Drug Release ◽  
Infrared Light ◽  
Upconversion Nanoparticles ◽  
Near Infrared Light ◽  
Nir Light ◽  
Triggered Drug Release

The preparation of a new near-infrared (NIR) light-responsive nanocarrier for controlled drug release is demonstrated.

Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways

2020 ◽  
Vol 56 (45) ◽  
pp. 6118-6121
Author(s):  
Juan Song ◽  
Jian-Bin Pan ◽  
Wei Zhao ◽  
Hong-Yuan Chen ◽  
Jing-Juan Xu
Keyword(s):  
Ion Channels ◽  
Protein Expression ◽  
Cell Apoptosis ◽  
Near Infrared ◽  
Gold Nanorod ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Apoptotic Protein ◽  
Apoptotic Pathways

We report a GNR-assisted NIR-activated tool that could open TRPV1 ion channels and regulate apoptotic protein expression, thereby inducing cell apoptosis.

Red and near-infrared light evokes Ca2+ influx, endoplasmic reticulum release and membrane depolarization in neurons and cancer cells

2021 ◽  
Vol 214 ◽  
pp. 112088
Author(s):  
Iuliia Golovynska ◽  
Sergii Golovynskyi ◽  
Yurii V. Stepanov ◽  
Liudmyla I. Stepanova ◽  
Junle Qu ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Cancer Cells ◽  
Near Infrared ◽  
Membrane Depolarization ◽  
Infrared Light ◽  
Near Infrared Light

scholarly journals Drug Delivery: Near-Infrared Light-Triggered, Targeted Drug Delivery to Cancer Cells by Aptamer Gated Nanovehicles (Adv. Mater. 21/2012)

2012 ◽  
Vol 24 (21) ◽  
pp. 2798-2798
Author(s):  
Xinjian Yang ◽  
Xia Liu ◽  
Zhen Liu ◽  
Fang Pu ◽  
Jinsong Ren ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Targeted Drug Delivery ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Targeted Drug

Construction of perfluorohexane/IR780@liposome coating on Ti for rapid bacteria killing under permeable near infrared light

2018 ◽  
Vol 6 (9) ◽  
pp. 2460-2471 ◽  
Author(s):  
Xiuhua Wang ◽  
Lei Tan ◽  
Xiangmei Liu ◽  
Zhenduo Cui ◽  
Xianjin Yang ◽  
...  
Keyword(s):  
Antibacterial Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Nir Light ◽  
Penetration Ability ◽  
Bacteria Killing

Near infrared (NIR) light induced photodynamic antibacterial therapy (PDAT) is a promising antibacterial technique in rapidin situdisinfection of bacterially infected artificial implants due to its penetration ability into tissues.

A multifunctional nanoplatform for lysosome targeted delivery of nitric oxide and photothermal therapy under 808 nm near-infrared light

2016 ◽  
Vol 4 (27) ◽  
pp. 4667-4674 ◽  
Author(s):  
Hui-Jing Xiang ◽  
Min Guo ◽  
Lu An ◽  
Shi-Ping Yang ◽  
Qian-Ling Zhang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Targeted Delivery ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Nir Light

NIR light induced spatiotemporal delivery of NO to lysosome accompanied by hyperthermia was realized.

scholarly journals Near infrared light-driven water oxidation in a molecule-based artificial photosynthetic device using an upconversion nano-photosensitizer

2015 ◽  
Vol 51 (65) ◽  
pp. 13008-13011 ◽  
Author(s):  
Xiaomin Liu ◽  
Hung-Cheng Chen ◽  
Xianggui Kong ◽  
Youlin Zhang ◽  
Langping Tu ◽  
...  
Keyword(s):  
Water Oxidation ◽  
Near Infrared ◽  
Infrared Light ◽  
Upconversion Nanoparticles ◽  
Near Infrared Light ◽  
Photosynthetic System ◽  
Nir Light ◽  
Artificial Photosynthetic ◽  
Novel Concept

A NIR light driven nano-photosensitizer is reported as a novel concept in an artificial photosynthetic system that integrates upconversion nanoparticles with Pt(ii)-porphyrin.

Ultralow-intensity near infrared light synchronously activated collaborative chemo/photothermal/photodynamic therapy

2020 ◽  
Vol 8 (2) ◽  
pp. 607-618 ◽  
Author(s):  
Renlu Han ◽  
Keqi Tang ◽  
Yafei Hou ◽  
Jiancheng Yu ◽  
Chenlu Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Nir Light

An ultralow-intensity 808 nm NIR light with 0.25 W cm−2 synchronously activated collaborative Chemo/Photothermal/Photodynamic therapy system was developed.

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