scholarly journals Prospective randomized trial evaluating blood and prostate tissue concentrations of green tea polyphenols and quercetin in men with prostate cancer

2020 ◽  
Vol 11 (5) ◽  
pp. 4114-4122
Author(s):  
Susanne M. Henning ◽  
Piwen Wang ◽  
Ru-Po Lee ◽  
Amy Trang ◽  
George Husari ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Randomized Trial ◽  
Green Tea ◽  
Epigallocatechin Gallate ◽  
Potential Effect ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Prostate Tissue ◽  
Epicatechin Gallate ◽  
Tissue Concentrations

Epigallocatechin gallate, epicatechin gallate (Green Tea Polyphenols – GTPs) and quercetin (Q) were taken up in prostate tissue after Q and GTP consumption. Our findings herein suggest a potential effect of Q on GTP metabolism.

Separation of epigallocatechin gallate and epicatechin gallate from tea polyphenols by macroporous resin and crystallization

2021 ◽  
Author(s):  
Li Wang ◽  
Xin Huang ◽  
Huijuan Jing ◽  
Xin Ye ◽  
Chao Jiang ◽  
...  
Keyword(s):  
Green Tea ◽  
Epigallocatechin Gallate ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Macroporous Resin ◽  
Epicatechin Gallate

Epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) are the most abundant ester catechins of green tea polyphenols (GTPs) with numerous potential bioactivities, which have a wide application prospect in the...

scholarly journals Anti-Cancer Effects of Green Tea Polyphenols Against Prostate Cancer

Molecules ◽  
2019 ◽  
Vol 24 (1) ◽  
pp. 193 ◽  
Author(s):  
Yasuyoshi Miyata ◽  
Yohei Shida ◽  
Tomoaki Hakariya ◽  
Hideki Sakai
Keyword(s):  
Prostate Cancer ◽  
Green Tea ◽  
Molecular Mechanisms ◽  
Current Knowledge ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Anti Cancer ◽  
Prevention And Treatment

Prostate cancer is the most common cancer among men. Green tea consumption is reported to play an important role in the prevention of carcinogenesis in many types of malignancies, including prostate cancer; however, epidemiological studies show conflicting results regarding these anti-cancer effects. In recent years, in addition to prevention, many investigators have shown the efficacy and safety of green tea polyphenols and combination therapies with green tea extracts and anti-cancer agents in in vivo and in vitro studies. Furthermore, numerous studies have revealed the molecular mechanisms of the anti-cancer effects of green tea extracts. We believe that improved understanding of the detailed pathological roles at the molecular level is important to evaluate the prevention and treatment of prostate cancer. Therefore, in this review, we present current knowledge regarding the anti-cancer effects of green tea extracts in the prevention and treatment of prostate cancer, with a particular focus on the molecular mechanisms of action, such as influencing tumor growth, apoptosis, androgen receptor signaling, cell cycle, and various malignant behaviors. Finally, the future direction for the use of green tea extracts as treatment strategies in patients with prostate cancer is introduced.

scholarly journals Green Tea Polyphenols Induce p53-Dependent and p53-Independent Apoptosis in Prostate Cancer Cells through Two Distinct Mechanisms

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e52572 ◽  
Author(s):  
Karishma Gupta ◽  
Vijay S. Thakur ◽  
Natarajan Bhaskaran ◽  
Akbar Nawab ◽  
Melissa A. Babcook ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Green Tea ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Prostate Cancer Cells

scholarly journals Epigallocatechin Gallate (EGCG), a Green Tea Polyphenol, Reduces Coronavirus Replication in a Mouse Model

Viruses ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2533
Author(s):  
Rackhyun Park ◽  
Minsu Jang ◽  
Yea-In Park ◽  
Yeonjeong Park ◽  
Woochul Jung ◽  
...  
Keyword(s):  
Mouse Model ◽  
Green Tea ◽  
Particle Production ◽  
Epigallocatechin Gallate ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Tea Polyphenol ◽  
Green Tea Polyphenol

The COVID-19 pandemic has resulted in a huge number of deaths from 2020 to 2021; however, effective antiviral drugs against SARS-CoV-2 are currently under development. Recent studies have demonstrated that green tea polyphenols, particularly EGCG, inhibit coronavirus enzymes as well as coronavirus replication in vitro. Herein, we examined the inhibitory effect of green tea polyphenols on coronavirus replication in a mouse model. We used epigallocatechin gallate (EGCG) and green tea polyphenols containing more than 60% catechin (GTP60) and human coronavirus OC43 (HCoV-OC43) as a surrogate for SARS-CoV-2. Scanning electron microscopy analysis results showed that HCoV-OC43 infection resulted in virion particle production in infected cells. EGCG and GTP60 treatment reduced coronavirus protein and virus production in the cells. Finally, EGCG- and GTP60-fed mice exhibited reduced levels of coronavirus RNA in mouse lungs. These results demonstrate that green tea polyphenol treatment is effective in decreasing the level of coronavirus in vivo.

scholarly journals Green tea polyphenols and Tai Chi for bone health: Designing a placebo-controlled randomized trial

2009 ◽  
Vol 10 (1) ◽  
Author(s):  
Chwan-Li Shen ◽  
Ming-Chien Chyu ◽  
James K Yeh ◽  
Carol K Felton ◽  
Ke T Xu ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Green Tea ◽  
Bone Health ◽  
Tai Chi ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols
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