Platelet membrane-coated nanoparticles for targeted drug delivery and local chemo-photothermal therapy of orthotopic hepatocellular carcinoma

2020 ◽  
Vol 8 (21) ◽  
pp. 4648-4659 ◽  
Author(s):  
Long Wu ◽  
Wei Xie ◽  
Hui-Ming Zan ◽  
Zhongzhong Liu ◽  
Ganggang Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Platelet Membrane ◽  
Coated Nanoparticles ◽  
Controllable Release ◽  
Targeted Drug

Specific targeted drug delivery and controllable release of drugs at tumor regions are two of the main challenges for hepatocellular carcinoma (HCC) therapy, particularly post metastasis.

Macrophage membrane coated nanoparticles: a biomimetic approach for enhanced and targeted delivery

2022 ◽  
Author(s):  
Nafeesa Khatoon ◽  
Zefei Zhang ◽  
Chunhui Zhou ◽  
Maoquan Chu
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Targeted Delivery ◽  
Systemic Toxicity ◽  
Coated Nanoparticles ◽  
Biomimetic Approach ◽  
Targeted Drug ◽  
Macrophage Membrane

The enhanced and targeted drug delivery with low systemic toxicity and subsequent release of drugs is the major concern among researchers and pharmaceutics. Inspite of greater advancement and discoveries in...

Polypeptide-Engineered Hydrogel Coated Gold Nanorods for Targeted Drug Delivery and Chemo-photothermal Therapy

2017 ◽  
Vol 3 (10) ◽  
pp. 2391-2398 ◽  
Author(s):  
Jie Yang ◽  
Ming-Hao Yao ◽  
Rui-Mei Jin ◽  
Dong-Hui Zhao ◽  
Yuan-Di Zhao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanorods ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Targeted Drug

A facile approach to functionalizing cell membrane-coated nanoparticles with neurotoxin-derived peptide for brain-targeted drug delivery

2017 ◽  
Vol 264 ◽  
pp. 102-111 ◽  
Author(s):  
Zhilan Chai ◽  
Xuefeng Hu ◽  
Xiaoli Wei ◽  
Changyou Zhan ◽  
Linwei Lu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cell Membrane ◽  
Targeted Drug Delivery ◽  
Coated Nanoparticles ◽  
Targeted Drug

Multifunctional magnetic-gold nanoparticles for efficient combined targeted drug delivery and interstitial photothermal therapy

2019 ◽  
Vol 554 ◽  
pp. 256-263 ◽  
Author(s):  
Nihal S. Elbialy ◽  
Mohamed M. Fathy ◽  
Reem AL-Wafi ◽  
Reem Darwesh ◽  
Umama A. Abdel-dayem ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Targeted Drug

Recent advances in combinatorial cancer therapy via multifunctionalized gold nanoparticles

Nanomedicine ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. 1221-1237
Author(s):  
Touqeer Ahmad ◽  
Rizwana Sarwar ◽  
Ayesha Iqbal ◽  
Uzma Bashir ◽  
Umar Farooq ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Therapeutic Implications ◽  
Therapeutic Applications ◽  
Diagnosis Of Cancer ◽  
Targeted Drug ◽  
Cancerous Cells

The diverse behavior of nanogold in the therapeutic field is related to its unique size and shape. Nanogold offers improvements in modern diagnostic and therapeutic implications, increases disease specificity and targeted drug delivery, and is relatively economical compared with other chemotherapeutic protocols. The diagnosis of cancer and photothermal therapy improve drastically with the implementation of nanotechnology. Different types of nanoparticles, that is, gold silica nanoshells, nanorods and nanospheres of diverse shapes and geometries, are used widely in the photothermal therapy of cancerous cells and nodules. Numerous reviews have been published on the therapeutic applications of gold nanoparticles, but studies on combinatorial applications of nanogold in cancer therapy are limited. This review focuses on the combinatorial cancer therapy using optical properties of nanogold with different shapes and geometries, and their therapeutic applications in cancer diagnosis, photothermal therapy, cancer imaging and targeted drug delivery.

scholarly journals Dual-Ligand Functionalized Core-Shell Chitosan-Based Nanocarrier for Hepatocellular Carcinoma-Targeted Drug Delivery

2020 ◽  
Vol Volume 15 ◽  
pp. 821-837 ◽  
Author(s):  
Amr Hefnawy ◽  
Islam H Khalil ◽  
Kholoud Arafa ◽  
Marwan Emara ◽  
Ibrahim M El-Sherbiny
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Core Shell ◽  
Targeted Drug

Overcoming multidrug resistance by a combination of chemotherapy and photothermal therapy mediated by carbon nanohorns

2016 ◽  
Vol 4 (36) ◽  
pp. 6043-6051 ◽  
Author(s):  
Junling Wang ◽  
Ran Wang ◽  
Fangrong Zhang ◽  
Yajun Yin ◽  
Leixia Mei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Multidrug Resistance ◽  
Drug Delivery System ◽  
Delivery System ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Carbon Nanohorns ◽  
P Glycoprotein ◽  
Targeted Drug ◽  
Targeted Drug Delivery System

A targeted drug delivery system based on carbon nanohorns for targeting P-glycoprotein and delivering etoposide into cells to overcome multidrug resistance.

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