Label-free Quantitation of the Changes in Salivary Proteome associated with the Chronic Consumption of the Betel nut (Areca Catechu)

2021 ◽  
Author(s):  
Munazza Raza ◽  
Rabia Sultan ◽  
Muhammad I Choudhary ◽  
Muhammad Tahir ◽  
Martin R. Larsen ◽  
...  
Keyword(s):  
High Risk ◽  
Oral Cancer ◽  
Areca Nut ◽  
Betel Nut ◽  
Label Free ◽  
Areca Catechu ◽  
Betel Nut Chewing ◽  
Label Free Quantitation

Areca nut or betel nut chewing is most frequently used in Pakistan and is associated with a high risk for oral cancer. Until now, however, there has not been any...

scholarly journals Assessment of the Risk of Oral Cancer Incidence in A High-Risk Population and Establishment of A Predictive Model for Oral Cancer Incidence Using A Population-Based Cohort in Taiwan

2020 ◽  
Vol 17 (2) ◽  
pp. 665 ◽  
Author(s):  
Li-Chen Hung ◽  
Pei-Tseng Kung ◽  
Chi-Hsuan Lung ◽  
Ming-Hsui Tsai ◽  
Shih-An Liu ◽  
...  
Keyword(s):  
High Risk ◽  
Oral Cancer ◽  
Predictive Model ◽  
Cancer Incidence ◽  
Predictive Ability ◽  
High Risk Population ◽  
Betel Nut ◽  
Risk Population ◽  
Oral Cancer Screening ◽  
Betel Nut Chewing

We aimed to assess the risk of oral cancer incidence in a high-risk population, establish a predictive model for oral cancer among these high-risk individuals, and assess the predictive ability of the constructed model. Individuals aged ≥30 years who had a habit of smoking or betel nut chewing and had undergone oral cancer screening in 2010 or 2011 were selected as study subjects. The incidence of oral cancer among the subjects at the end of 2014 was determined. The annual oral cancer incidence among individuals with a positive screening result was 624 per 100,000 persons, which was 6.5 times that of the annual oral cancer incidence among all individuals screened. Male sex, aged 45–64 years, divorce, low educational level, presence of diabetes, presence of other cancers, high comorbidity severity, a habit of smoking or betel nut chewing, and low monthly salary were high-risk factors for oral cancer incidence (p < 0.05). The area under the curve of the predictive model for oral cancer incidence was 0.73, which indicated a good predictive ability. Therefore, the oral cancer screening policy for the high-risk population with a habit of smoking and/or betel nut chewing is beneficial for the early diagnosis of oral cancer.

Betel Nut Chewing in Iron Age Vietnam? Detection of Areca catechu Alkaloids in Dental Enamel

2016 ◽  
Vol 49 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Simone Krais ◽  
Miriam Klima ◽  
Laura M. Huppertz ◽  
Volker Auwärter ◽  
Markus J. Altenburger ◽  
...  
Keyword(s):  
Iron Age ◽  
Dental Enamel ◽  
Betel Nut ◽  
Areca Catechu ◽  
Betel Nut Chewing

scholarly journals Aktivitas Antimikroba Ekstrak Etanol Biji Pinang Muda (Areca catechu)

2019 ◽  
Vol 10 ◽  
pp. 135-138
Author(s):  
Sega Ade Lilyawati ◽  
Nurul Fitriani ◽  
Fajar Prasetya
Keyword(s):  
Fungal Infections ◽  
Ethanol Extract ◽  
Negative Control ◽  
Oral Disease ◽  
Areca Nut ◽  
Antimicrobial Compounds ◽  
Betel Nut ◽  
Streptococcus Sanguis ◽  
Areca Catechu ◽  
Bacteria And Fungi

Thrush is an oral disease caused by bacterial and fungal infections. Treatment for this disease can be done by administering drugs that contain antimicrobial compounds. This study aims to test the ethanol extract of young areca nut against bacteria and fungi that cause Oral thrush. Young betel nut extract is obtained through maceration process using 96% ethanol. Then the activity of the Streptococcus sanguis bacteria and Candida albican fungus was tested. This test used the well method which was carried out on 5 variations of the concentration of young areca nut extract (2.5%; 5%; 7.5%; 10% and 15%) with one negative control (Na CMC). The results of the antimicrobial activity of young areca nut extract showed that young areca nut extract can inhibit Streptococcus sanguis bacteria with inhibition value are  (9,961; 11,319; 13,390; 14,184; 14,704 mm) and Candida albican fungus are (7,482; 10,923; 14,695; 15,742; 17,325 mm) on 5 variations of the concentration.

scholarly journals Areca catechu nut: a double-edged sword

2017 ◽  
Vol 6 (3) ◽  
pp. 700
Author(s):  
Ajitha Sharma
Keyword(s):  
Antioxidant Activity ◽  
Spatial Memory ◽  
East Asian ◽  
Areca Nut ◽  
Betel Nut ◽  
Asian Countries ◽  
Learning Behaviour ◽  
Areca Catechu ◽  
In Vitro Antioxidant Activity

The chewing of Areca catechu nut, more popularly known as betel nut, is one of the ancient traditions in India and other South-east Asian countries. Other than its role played in religious practices and cultural rituals, areca nut has also been described to have various health benefits, particularly antihelminthic and antiviral properties, in the traditional systems of medicine like Ayurveda. It was observed to produce an antidepressant-like effect by elevating the serotonin and norepinephrine levels in hippocampus of rats. It also exhibited analgesic and anti-inflammatory activities in mice, and displayed in vitro antioxidant activity. Furthermore, it was found to improve spatial memory and learning behaviour in rats.

scholarly journals PRITHVI MAHABHUTA DOMINANT CHARACTERS IN PUGAPHALA (ARECA CATECHU LINN.) SCIENTIFICALLY ASSESSED THROUGH PHARMACOGNOSY AND PHARMACEUTICAL CHEMISTRY

2018 ◽  
Vol 10 (4) ◽  
pp. 75
Author(s):  
Kamla Moond ◽  
Hitesh Vyas ◽  
Harisha C. R. ◽  
V. J. Shukla
Keyword(s):  
Chemical Analysis ◽  
Pharmaceutical Chemistry ◽  
Areca Nut ◽  
Betel Nut ◽  
Tropical Fruit ◽  
Areca Catechu ◽  
The World ◽  
Powdered Form ◽  
Different Parts

Objective: The Areca catechu L. is a tropical fruit, which is also called betel nut and is widely distributed in different parts of the world. Areca catechu L is used for various treatment aliments in the form of various preparations especially in powdered form and it used extensively in Ayurveda to treat Mukhavikara, Aruchi, Yonishaithilya, Shvetapradara etc. Areca nut is commonly used as betel nut or supari, as it is often chewed wrapped in betel leaves (Paan). The aim is to assessment of Mahabhautika dominance in Pugaphala by pharmacognostical and pharmaceutical study.Methods: Microscopic, macroscopic study and phsico-chemical analysis of Pugaphala Churna.Results: In present study Pugaphala was selected as a Parthiva dominant drug according to its Rasa Panchaka, after that its Mahabhautika dominancy was assessed by pharmacognostical and pharmaceutical study and results also support that in Pharmaceutical study loss on drying is 4.4%w/w, in Pharmacognostical study Rhomboidal crystal, Lignified scleroid etc. were found these characters also showed that Pugaphala is having dominancy of Prithvi Mahabhuta.Conclusion: Prithvi dominancy in Pugaphala is scientifically assessed by Pharmacognostical and Pharmaceutical study.

Implication for second primary cancer from visible oral and oropharyngeal premalignant lesions in betel-nut chewing related oral cancer

Head & Neck ◽  
2017 ◽  
Vol 39 (7) ◽  
pp. 1428-1435
Author(s):  
Shyun-Yu Liu ◽  
I-Jung Feng ◽  
Yu-Wei Wu ◽  
Ching-Yuan Chen ◽  
Chao-Nan Hsiung ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Premalignant Lesions ◽  
Second Primary ◽  
Primary Cancer ◽  
Betel Nut ◽  
Second Primary Cancer ◽  
Betel Nut Chewing
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