Exploiting the role of stereoelectronic effects to design the antagonists of human complement C3a receptor.
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The stereoelectronic effects are crucial in governing the conformational behaviour of the small molecules bearing heterocyclic ring adjacent to amides. It dictates the antagonist and agonist activity for G-protein coupled...
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2007 ◽
Vol 282
(48)
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pp. 34968-34976
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1996 ◽
Vol 74
(10)
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pp. 1095-1110
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2006 ◽
Vol 99
(5)
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pp. 905-909
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2000 ◽
Vol 279
(1)
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pp. G201-G210
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