Molecular biology of acetyl-CoA metabolism
2000 ◽
Vol 28
(6)
◽
pp. 591-593
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Keyword(s):
We have characterized the expression of potential acetyl-CoA-generating genes (acetyl-CoA synthetase, pyruvate decarboxylase, acetaldehyde dehydrogenase, plastidic pyruvate dehydrogenase complex and ATP-citrate lyase), and compared these with the expression of acetyl-CoA-metabolizing genes (heteromeric and homomeric acetyl-CoA carboxylase). These comparisons have led to the development of testable hypotheses as to how distinct pools of acetyl-CoA are generated and metabolized. These hypotheses are being tested by combined biochemical, genetic and molecular biological experiments, which is providing insights into how acetyl-CoA metabolism is regulated.
1983 ◽
Vol 302
(1108)
◽
pp. 33-45
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Keyword(s):
1996 ◽
Vol 47
(12)
◽
pp. 1889-1896
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1992 ◽
Vol 38
(12)
◽
pp. 1313-1319
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1980 ◽
Vol 33
(1)
◽
pp. 15
◽
Keyword(s):
1986 ◽
Vol 157
(3)
◽
pp. 553-561
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Keyword(s):