Type V Bekesy Pattern: Interpretation and Clinical Utility

1967 ◽  
Vol 10 (4) ◽  
pp. 733-744 ◽  
Author(s):  
William F. Rintelmann ◽  
Earl R. Harford
Keyword(s):  
Clinical Utility ◽  
The Past ◽  
Type V ◽  
Clinical Cases

Recent studies indicate there is some disagreement concerning the interpretation and clinical utility of the Type V Bekesy pattern. Bekesy tracings obtained over the past six years from a sample of clinical cases were analyzed and a definition was established for the Type V pattern. This definition was applied to Bekesy tracings obtained from normal listeners, hypoacusics, and pseudohypoacusics. The Type V pattern was found frequently among pseudohypoacusics and only rarely among other individuals.

scholarly journals The Clinical Utility of Virtual Reality in Neurorehabilitation: A Systematic Review

2018 ◽  
Vol 10 ◽  
pp. 117957351881354 ◽  
Author(s):  
Thais Massetti ◽  
Talita Dias da Silva ◽  
Tânia Brusque Crocetta ◽  
Regiani Guarnieri ◽  
Bruna Leal de Freitas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Virtual Reality ◽  
Virtual Environments ◽  
Neurological Disorders ◽  
Clinical Utility ◽  
Spinal Cord Injuries ◽  
Web Of Science ◽  
The Past ◽  
Meta Analyses ◽  
The Impact

Background: Virtual reality (VR) experiences (through games and virtual environments) are increasingly being used in physical, cognitive, and psychological interventions. However, the impact of VR as an approach to rehabilitation is not fully understood, and its advantages over traditional rehabilitation techniques are yet to be established. Method: We present a systematic review which was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). During February and March of 2018, we conducted searches on PubMed (Medline), Virtual Health Library Search Portal databases (BVS), Web of Science (WOS), and Embase for all VR-related publications in the past 4 years (2015, 2016, 2017, and 2018). The keywords used in the search were “neurorehabilitation” AND “Virtual Reality” AND “devices.” Results: We summarize the literature which highlights that a range of effective VR approaches are available. Studies identified were conducted with poststroke patients, patients with cerebral palsy, spinal cord injuries, and other pathologies. Healthy populations have been used in the development and testing of VR approaches meant to be used in the future by people with neurological disorders. A range of benefits were associated with VR interventions, including improvement in motor functions, greater community participation, and improved psychological and cognitive function. Conclusions: The results from this review provide support for the use of VR as part of a neurorehabilitation program in maximizing recovery.

scholarly journals Postmenopausal women – comorbid patients

2020 ◽  
Vol 1 (3) ◽  
pp. 30-38
Author(s):  
Tatyana Yu. Pestrikova ◽  
◽  
Elena A. Yurasova ◽  
Olga G. Sherbakova ◽  
Marina А. Shveeva ◽  
...  
Keyword(s):  
Healthcare Professionals ◽  
Social Significance ◽  
Average Life ◽  
Average Life Expectancy ◽  
The Past ◽  
Age Related ◽  
Menopausal Women ◽  
Comorbid Diseases ◽  
Clinical Cases

Relevance. As the prevention and treatment of diseases improves, the average life expectancy of the population increases. For many of our contemporaries, a third of their lives are postmenopausal. Menopause-related health problems are increasingly common and require the attention of healthcare professionals. Aim. To raise awareness of gynecologists, urologists and other specialists about the medico-social significance of the problems of women in the menopausal period based on the analysis of literature sources and analysis of clinical cases. Materials and methods. To write this review, a search was carried out for domestic and foreign publications in Russian and international search systems (PubMed, eLibrary, etc.) over the past 20 years. The review included articles from the peer-reviewed literature. An analysis of 2 clinical cases with comorbid pathology in menopausal patients is presented. Results. The review presents data on age-related physiological changes and quality of life in menopausal women. The analysis of 2 clinical cases of the appointment of menopausal hormone therapy in patients with comorbid diseases was carried out. Conclusions. The importance of awareness of outpatient doctors in the diagnosis and management tactics of patients with comorbid diseases in menopause is emphasized.

Improvements in and clinical utility of a continuous-flow method for routine measurement of dialyzable (ultrafiltrable) calcium.

1979 ◽  
Vol 25 (11) ◽  
pp. 1939-1943 ◽  
Author(s):  
J Toffaletti ◽  
G N Bowers
Keyword(s):  
Continuous Flow ◽  
Clinical Utility ◽  
Clinical Laboratory ◽  
Serum Samples ◽  
The Past ◽  
Baseline Noise ◽  
Routine Service ◽  
Routine Measurement ◽  
Routine Clinical Laboratory ◽  
Continuous Flow Method

Abstract We describe modifications to the original continuous-flow procedure for dialyzable calcium (Clin. Chem. 23: 1258, 1977) needed to make the method more suitable for routine clinical laboratory use. The modifications simplify the continuous-flow (AutoAnalyzer) manifold, decrease baseline noise, increase the sensitivity, and permit use of a less-expensive fluorometer. Bias due to variation in serum processing is minimized by use of serum samples minimally exposed to air and a pH 7.40 buffer in place of the routinely processed sera and pH 7.30 buffer used formerly. Day-to-day precision (CV) during the past year for samples that included three different lots of quality-control sera was 2 to 3%. The analysis requires 200 micro L of serum, collected with minor additional precautions. We find that dialyzable calcium can be dependably measured in the routine service laboratory and show how this information is clinically more useful than is information on total calcium in serum.

scholarly journals A Statistical Review of Clinical Cases with Tracheo-bronchial Foreign Bodies over the Past 29 Years.

1997 ◽  
Vol 48 (6) ◽  
pp. 445-450 ◽  
Author(s):  
Toshiya Takahashi ◽  
Yuji Kaneta ◽  
Yoko Odashima ◽  
Kazuo Murai
Keyword(s):  
Foreign Bodies ◽  
Statistical Review ◽  
The Past ◽  
Clinical Cases

Anti-Müllerian hormone in female reproduction

2021 ◽  
Author(s):  
Nathalie di Clemente ◽  
Chrystèle Racine ◽  
Alice Pierre ◽  
Joëlle Taieb
Keyword(s):  
Bone Morphogenetic Proteins ◽  
Clinical Utility ◽  
Polycystic Ovary ◽  
Large Body ◽  
Reproductive Organs ◽  
Female Reproduction ◽  
Ovary Syndrome ◽  
The Past ◽  
Pathological Conditions ◽  
Reliable Marker

Abstract Anti-Müllerian hormone (AMH), also called Müllerian inhibiting substance, was shown to be synthesized by the ovary in the eighties. This article reviews the main findings of the past 20 years on the regulation of the expression of AMH and its specific receptor AMHR2 by granulosa cells, the mechanism of action of AMH, the different roles it plays in the reproductive organs, its clinical utility and its involvement in the principal pathological conditions affecting women. The findings in respect of regulation tell us that AMH and AMHR2 expression is mainly regulated by Bone Morphogenetic Proteins, gonadotropins and estrogens. It has now been established that AMH regulates the different steps of folliculogenesis and that it has neuroendocrine effects. On the other hand, the importance of serum AMH as a reliable marker of ovarian reserve and as a useful tool in the prediction of the polycystic ovary syndrome (PCOS) and primary ovarian failure has also been acknowledged. Last but not least, a large body of evidence points to the involvement of AMH in the pathogenesis of PCOS.

scholarly journals Versatility of Aminoglycosides and Prospects for Their Future

2003 ◽  
Vol 16 (3) ◽  
pp. 430-450 ◽  
Author(s):  
Sergei B. Vakulenko ◽  
Shahriar Mobashery
Keyword(s):  
Bacterial Infections ◽  
Clinical Utility ◽  
Aminoglycoside Antibiotics ◽  
Mechanisms Of Resistance ◽  
Half Century ◽  
The Past ◽  
Past Half Century ◽  
Past Half

SUMMARY Aminoglycoside antibiotics have had a major impact on our ability to treat bacterial infections for the past half century. Whereas the interest in these versatile antibiotics continues to be high, their clinical utility has been compromised by widespread instances of resistance. The multitude of mechanisms of resistance is disconcerting but also illuminates how nature can manifest resistance when bacteria are confronted by antibiotics. This article reviews the most recent knowledge about the mechanisms of aminoglycoside action and the mechanisms of resistance to these antibiotics.

Analgesic efficacy of topical butamben picrate

1995 ◽  
Vol 85 (12) ◽  
pp. 738-740 ◽  
Author(s):  
DG Armstrong ◽  
IO Kanat
Keyword(s):  
Clinical Utility ◽  
Analgesic Efficacy ◽  
Topical Anesthetic ◽  
Topical Antibiotics ◽  
Pain Questionnaire ◽  
Topical Anesthetics ◽  
The Past ◽  
Past Generation ◽  
Mcgill University ◽  
Oral Analgesia

Over the past generation, advents in topical antibiotics and oral analgesia have obscured butamen and its family of topical anesthetics. Using a modified version of the McGill University pain questionnaire, this study attempts to establish the efficacy and clinical utility of this overlooked topical anesthetic.

scholarly journals Making a medicine out of MDMA

2015 ◽  
Vol 206 (1) ◽  
pp. 4-6 ◽  
Author(s):  
Ben Sessa ◽  
David Nutt
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Clinical Utility ◽  
Stress Disorder ◽  
Therapeutic Potential ◽  
Mental Illnesses ◽  
Post Traumatic Stress ◽  
Treatment Resistant ◽  
The Past ◽  
Post Traumatic

SummaryFrom its first use 3,4,-methylenedioxymethamphetamine (MDMA) has been recognised as a drug with therapeutic potential. Research on its clinical utility stopped when it entered the recreational drug scene but has slowly resurrected in the past decade. Currently there is enough evidence for MDMA to be removed from its Schedule 1 status of ‘no medical use’ and moved into Schedule 2 (alongside other misused but useful medicines such as heroin and amphetamine). Such a regulatory move would liberate its use as a medicine for patients experiencing severe mental illnesses such as treatment-resistant post-traumatic stress disorder.

Dopaminergic imaging: clinical utility now and in the future

2011 ◽  
Vol 23 (S2) ◽  
pp. S32-S40 ◽  
Author(s):  
Zuzana Walker ◽  
Joanne Rodda
Keyword(s):  
Clinical Practice ◽  
Dementia With Lewy Bodies ◽  
Clinical Utility ◽  
Lewy Bodies ◽  
Present Knowledge ◽  
Parkinsonian Syndromes ◽  
The Past ◽  
Future Clinical Practice ◽  
The Future ◽  
Diagnosis Of Dementia

ABSTRACTOver the past ten years, dopaminergic imaging has become increasingly part of the assessment and diagnosis of dementia. There are numerous PET and SPECT ligands available that target different steps in the process of neurotransmission. Abnormalities in dopaminergic imaging measures are consistent features of dementia with Lewy bodies (DLB) and other parkinsonian syndromes, and can be used to facilitate diagnosis, particularly in distinguishing between DLB and Alzheimer's disease. This review summarizes present knowledge in this area and the implications for current and future clinical practice.

scholarly journals What do young people worry about? A systematic review of worry theme measures of teen and preteen individuals

2020 ◽  
Vol 45 (4) ◽  
pp. 285-295
Author(s):  
Marcin Owczarek ◽  
Grainne McAnee ◽  
Donal McAteer ◽  
Mark Shevlin
Keyword(s):  
Systematic Review ◽  
Young People ◽  
School Performance ◽  
Clinical Utility ◽  
Web Of Science ◽  
Developmental Trajectories ◽  
The State ◽  
The Past ◽  
Qualitative Approaches

AbstractExcessive worry can negatively influence one’s developmental trajectories. In the past 70 years, there have been studies aimed towards documenting and analysing concerns or ‘worries’ of teen and preteen individuals. There have been many quantitative and qualitative approaches established, suggesting different themes of contextual adolescent worry. With the hopes of future clinical utility, it is important to parse through these studies and gather what is currently known about what teens and preteens worry about and what is the state of methods used to gather that knowledge. Studies were searched for using Web of Science, PubMed, PsycINFO, Scopus and ScienceDirect databases and selected on systematic criteria. Data regarding the country in which the study took place, participants, methods of collection, worry themes and conclusions and limitations were extracted. Data were synthesised in a narrative fashion. It was concluded that currently available methods of measuring themes of adolescent worry face certain problems. Themes of worry differ substantially between the studies, with the exception of school performance seeing stable high endorsement across cultures and ages. Issues with ordering worry themes and implications for future understanding of adolescent and preadolescent worry are discussed.

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