Chronic Daily Headache- One Disease Or Two.? Diagnostic Role of Serum Ionized Magnesium

Cephalalgia ◽  
1994 ◽  
Vol 14 (1) ◽  
pp. 24-28 ◽  
Author(s):  
A Mauskop ◽  
BT Altura ◽  
RQ Cracco ◽  
BM Altura
Keyword(s):  
Chronic Daily Headache ◽  
High Incidence ◽  
Current Classification ◽  
Diagnostic Role ◽  
History Of ◽  
Daily Headache ◽  
Calcium Magnesium ◽  
Drug Overuse ◽  
Tension Type Headaches

The entity of chronic daily headache (CDH) is well documented, but is not included in the current classification. We divided patients with CDH into groups with and without migrainous features. This division resulted in clearly distinguishable syndromes of daily migrainous headaches (DMH) and daily tension-type headaches (DTH). Family history of headaches was more common in patients with DMH. Patients in both groups had a high incidence of caffeine or drug overuse. The clinical division into DMH and DTH was supported by our finding of a higher incidence of disturbed magnesium (Mg) metabolism in patients with DMH. Of 26 patients with DMH, 8 (30.8%) had low serum ionized, but not total, Mg levels, and 16 (61.5%) had high ionized calcium/magnesium ratios. The corresponding numbers for the 22 patients with DTH were 1 (4.5%) and 8 (30.4%). These new laboratory measurements offer possible biological markers for the diagnosis of different headache syndromes.

Utility of CSF Pressure Monitoring to Identify Idiopathic Intracranial Hypertension without Papilledema in Patients with Chronic Daily Headache

Cephalalgia ◽  
2004 ◽  
Vol 24 (6) ◽  
pp. 495-502 ◽  
Author(s):  
MT Torbey ◽  
RG Geocadin ◽  
AY Razumovsky ◽  
D Rigamonti ◽  
MA Williams
Keyword(s):  
Intracranial Hypertension ◽  
Chronic Daily Headache ◽  
Idiopathic Intracranial Hypertension ◽  
Pulse Amplitude ◽  
Shunt Insertion ◽  
Csf Drainage ◽  
Plateau Waves ◽  
Objective Evidence ◽  
Diagnostic Role ◽  
Daily Headache

The aim of the present study was to report on the utility of continuous Pcsf monitoring in establishing the diagnosis of idiopathic intracranial hypertension without papilledema (IIHWOP) in chronic daily headache (CDH) patients. We report a series of patients ( n = 10) with refractory headaches and suspected IIHWOP referred to us for continuous Pcsf monitoring between 1991 and 2000. Pcsf was measured via a lumbar catheter and analysed for mean, peak, highest pulse amplitude and abnormal waveforms. A 1-2 day trial of continuous controlled CSF drainage (10 cc/h) followed Pcsf monitoring. Response to CSF drainage was defined as improvement in headache symptoms. Patients with abnormal waveforms underwent a ventriculoperitoneal (VPS) or lumboperitoneal (LPS) shunt insertion. All patients had normal resting Pcsf (8 ± 1 mmHg) defined as ICP < 15 mmHg. During sleep, all patients had B-waves and 90% had plateau waves or near plateau waves. All patients underwent either a VPS or LPS procedure. All reported improvement of their headache after surgery. Demonstration of pathological Pcsf patterns by continuous Pcsf monitoring was essential in confirming the diagnosis of IIHWOP, and provided objective evidence to support the decision for shunt surgery. Increased Pcsf was seen mostly during sleep and was intermittent, suggesting that Pcsf elevation may be missed by a single spot-check LP measurement. The similarity between IIHWOP and CDH suggests that continuous Pcsf monitoring in CDH patients may have an important diagnostic role that should be further investigated.

Transformed migraine

Cephalalgia ◽  
1993 ◽  
Vol 13 (12_suppl) ◽  
pp. 78-83 ◽  
Author(s):  
Ninan T Mathew
Keyword(s):  
Chronic Daily Headache ◽  
Tension Type Headache ◽  
Drug Induced ◽  
Chronic Tension Type Headache ◽  
Transformed Migraine ◽  
Mixed Features ◽  
History Of ◽  
Daily Headache ◽  
International Headache Classification ◽  
Type Headache

Chronic tension-type headache, which is included in the International Headache Classification, is present in only a minority of patients who present with chronic daily headache. The majority have what is termed transformed migraine, with a history of distinct episodes of migraine in the initial years which progresses into chronic daily headache. These patients with transformed migraine exhibit mixed features of migraine and chronic tension-type headache. Two distinct types of transformed migraine are identifiable, namely those related to excessive intake of medications (drug-induced transformed migraine) and those unrelated to excessive use of medications. The clinical features of transformed migraine and the drug-induced variety are described. The need for revision of the International Classification to include chronic daily headache and the subtypes of transformed migraine is pointed out.

scholarly journals Current and future role of immobilized enzymes in medical field

2021 ◽  
Vol 5 (01) ◽  
pp. 1-9
Author(s):  
Mohammad Rafiq Khan
Keyword(s):  
Immobilized Enzymes ◽  
Review Of The Literature ◽  
Research Groups ◽  
Medical Field ◽  
Future Role ◽  
Current Classification ◽  
Current Century ◽  
History Of

Although the history of immobilized enzymes and their applications in different fields are traced back to the second half of the twentieth century, their importance in bioreactors and biosensors highlighted at the turn of the current century is under active consideration in these days for broad-spectrum applications in different medical fields. Thus, this article presents a review of the literature concerning the current and future role of the immobilized enzymes in different medical fields. As the author and his supervised research groups have also been actively involved in research on immobilized enzymes, he has also made some input with a recommendation to revise the current classification of immobilized enzymes basically into “Naturally Immobilized” and “Artificially Immobilized Enzymes”, keeping the sub-classification intact. He has also suggested the development of some medical products based on the results of his research groups.

Diagnostic role of fine-needle aspiration of bone lesions in patients with a previous history of malignancy

2002 ◽  
Vol 26 (6) ◽  
pp. 380-383 ◽  
Author(s):  
Diana Treaba ◽  
Lina Assad ◽  
Hema Govil ◽  
Dinesh Sariya ◽  
Vijaya B. Reddy ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Previous History ◽  
Needle Aspiration ◽  
Bone Lesions ◽  
Fine Needle ◽  
Diagnostic Role ◽  
History Of

Are There Predictive Factors for Long-Term Outcome after Withdrawal in Drug-Induced Chronic Daily Headache?

Cephalalgia ◽  
2001 ◽  
Vol 21 (6) ◽  
pp. 691-696 ◽  
Author(s):  
GG Tribl ◽  
P Schnider ◽  
C Wöber ◽  
S Aull ◽  
A Auterith ◽  
...  
Keyword(s):  
Chronic Daily Headache ◽  
Favourable Outcome ◽  
Drug Induced ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Clear Cut ◽  
Standardized Interview ◽  
Daily Headache ◽  
Drug Overuse

Objectives To investigate prognostic factors for long-term outcome of patients after inpatient withdrawal because of drug-induced chronic daily headache. Procedures Fifty-five patients (36 females) were re-examined by means of a standardized interview after inpatient withdrawal. The mean observation period was 9.28 ± 2.85 years (mean ± sd; median 8.58; range 5.00–13.50). Results Five years after withdrawal, one-third of the patients (34.6%) had an overall favourable outcome, one-third (32.7%) had no recurrent drug overuse and reported a clear-cut improvement of headache, and one-third (32.7%) developed recurrent drug overuse. Most relapses occurred within 2 years, and a small percentage within 5 years. No predictors for long-term outcome after inpatient withdrawal were found. Conclusions All patients with drug-induced chronic daily headache should be considered as good candidates for inpatient withdrawal, and no patient should be excluded from that therapy.

scholarly journals The differential diagnosis of benign and malignant ovarian neoplasms (history)

2016 ◽  
Vol 65 (6) ◽  
pp. 68-78
Author(s):  
Mariya A Egunova ◽  
Irina G Kutsenko
Keyword(s):  
Ovarian Cancer ◽  
Differential Diagnosis ◽  
Ovarian Neoplasms ◽  
Imaging Techniques ◽  
Advantages And Disadvantages ◽  
Radiation Imaging ◽  
Preoperative Stage ◽  
High Incidence ◽  
History Of

The history of the differential diagnosis of ovarian neoplasms at the preoperative stage is presented in the review article. This is still a problem due to the high incidence of tumors and tumor-like formations of ovaries, the continuing upward trend in the index of ovarian cancer, along with a slight decrease in mortality and 5-year survival. Considerable success of surgical treatment and chemotherapy in the early stages of ovarian cancer suggests the earliest possible detection and accuracy of differential diagnosis of ovarian neoplasms. It highlights the role of the different research methods, including radiation imaging techniques, tumor markers and their potential advantages and disadvantages.

scholarly journals Infrequent Occurrence of Peach Skin Streaking and the Role of Rainwater Attributes on Symptom Development

Plant Disease ◽  
2019 ◽  
Vol 103 (10) ◽  
pp. 2606-2611
Author(s):  
L. T. Schmitz ◽  
G. Schnabel
Keyword(s):  
East Coast ◽  
Sample Volume ◽  
Oxidation Reduction ◽  
Oxidation Reduction Potential ◽  
Experimental Block ◽  
High Incidence ◽  
History Of ◽  
Cultivar Susceptibility ◽  
Production Areas

Streaks lacking pigmentation have impacted red blush cultivars of peaches in many East Coast production areas, but the underlying cause is still unclear. Some evidence suggests that streaking may be caused by reactive agents in rainwater. Peach skin streaking was monitored over two consecutive years at a commercial farm with a history of streaking problems located near Ridge Spring, SC. Six cultivars (two early season, two midseason, and two late season) were evaluated, each in two locations (LocA and LocB). Among those 12 experimental block cultivars, streaking occurred only in 2017 in cv. Scarletprince of LocA with an incidence of 6%. That same year two nearby nonexperimental blocks with ‘Scarletprince’ revealed 11 and 25% streaking. Streaking was also monitored at the Musser Fruit Research Center (MFRC) in Seneca, SC. At that location, a high incidence of streaking was observed, with 50 and 64% in ‘Julyprince’ (2017) and ‘Carored’ (2018), respectively. Rainwater pH taken from each of the 12 experimental blocks ranged from 3.03 to 7.4, ozone (O3) levels ranged from <0.02 to 0.37 mg/liter, and chlorine (Cl2) and chlorine dioxide (ClO2) levels were either just above or under the detection limit of 0.01 mg/liter and 0.02 mg/liter, respectively. Although the electrical conductivity (EC) was below 100 µS/cm on average, we did measure EC values as high as 1,500 µS/cm. For all samples, the oxidation-reduction potential (ORP) ranged from 90 to 302 mV, indicating oxidizing conditions. Fruit harvested 1 or 2 weeks prior to commercial maturity and treated with solutions of high (10) or low (3) pH, ozone >0.37 mg/liter, and EC values of up to 3,000 µS/cm did not produce symptoms. However, streaking was reproduced with collected rainwater, but the remaining sample volume did not allow further analyses. Using 0.05% ClO2 to induce streaking, we show that fruit of different cultivars varied in susceptibility when treated 1 week prior to commercial maturity, with ‘Juneflame’ being the most susceptible and ‘August Lady’ being the least susceptible. Our study shows that multiple factors determine the occurrence of streaking in peach orchards, including cultivar susceptibility, ripening stage, and the presence of rainwater with sufficient amounts of a yet unknown reactive agent or agent combination.

scholarly journals The role of blood pressures in patients with a headache

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Mehrdokht Mazdeh ◽  
Mojtaba Khazaei ◽  
Arezou Sayad ◽  
Javad Zebarjadi Bagherpour ◽  
Mohammad Taheri
Keyword(s):  
Blood Pressure ◽  
Cross Sectional Study ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
History Of ◽  
Daily Headache ◽  
Blood Pressures ◽  
Stage 1

Background: A headache is the most common cause of patients referred to the doctor. About 40 percent of people are suffering from a headache for at least once a year. Due to it's the high prevalence and its association with cardiovascular diseases, hypertension was considered as a  health problem in industrialized and developing countries. The aim of this study was to investigate the role of blood pressure in patients with a headache referred to the neurological clinic during  2014-2015 in Hamadan.Method: This cross-sectional study was performed to evaluate patients with a headache referred to the neurological clinic. Exclusion criteria included: a headache with a specific cause (a migraine, stroke, chronic daily headache, kidney disease, Diabetes Mellitus, history of heart disease or use of cigarette. The data were entered into the list and then were analyzed by SPSS software through paired T-test and chi-square test.Results: In this study, the 100 patients with a headache (78% females and 22% males) were investigated. The average age of patients was 60.07±13.175 years. The prevalence of stage 1 & 2 hypertension was 85%, and prehypertension prevalence of 7% was reported. Most of the headaches were in the frontal (33 %). Furthermore, the most headaches occur in varied time (70%). There wasn’t a significant correlation between age (P-value=0.698), gender (P-value=0.952), headache and blood pressure.Conclusion: The results obtained from the present study indicated that there was not any significant correlation between a headache and blood pressure, and the prevalence of blood pressure in the patients with a headache was similar to those who do not have headaches.Keywords: Blood Pressure, Hypertension, Headache

scholarly journals Climate change, biosystematics and taxonomy

2021 ◽  
Vol 28 (1) ◽  
pp. 277-287
Author(s):  
M Khairul Alam
Keyword(s):  
Climate Change ◽  
Phenotypic Plasticity ◽  
Environmental Conditions ◽  
Information Needs ◽  
Adaptive Significance ◽  
High Incidence ◽  
Plant Taxon ◽  
History Of ◽  
Impacts Of Climate Change

The history of biosystematics research and its impacts on climate goes before political ramifications. Climate change is altering the environments and likely to result in changes in the distribution of species, flowering times; migrate and adapt to the new environmental conditions; or extinction. Adaptive capacity is the ability of the plants to adapt to the impacts of climate change. Adaptation process is going in nature through phenotypic plasticity, natural selection or migration or polyploidization. The options are not mutually exclusive. Phenotypic plasticity may be the most efficient way of adaptation to a new environment. Polyploidization may increase tolerance to diverse ecological conditions and the high incidence of polyploidy in plants indicates its adaptive significance. Population having polyploid pillar complex is a good backup support towards microevolution and speciation, a mode of adaptation. The paper discusses about these biosystematics approaches towards adaptation to new environmental conditions resulting from climate change. It also discusses about the role of taxonomists under the changed circumstances. It is evident from the review that a set of biosystematics data along with other ecological and conservation information needs to be included in Flora and Monographs. It reveals that it was as far as worked out at the Paris Botanical Congress 1954 and put up by Stebbins in a series of proposals, termed as “Stebbins’ Ten Points” that needs further enrichment. Bangladesh J. Plant Taxon. 28(1): 277-287, 2021 (June)

Frequent Migraine and Migraine Status Without Tension-Type Headaches: an Unusual Presentation of Rebound Headaches

Cephalalgia ◽  
2003 ◽  
Vol 23 (4) ◽  
pp. 309-313 ◽  
Author(s):  
JS Warner
Keyword(s):  
Pain Relief ◽  
Chronic Daily Headache ◽  
Episodic Migraine ◽  
Unusual Presentation ◽  
Case Histories ◽  
Analgesic Agents ◽  
Daily Headache ◽  
Rebound Headache ◽  
Chronic Daily Headaches ◽  
Tension Type Headaches

Rebound headaches usually present as daily or almost daily, prolonged, generalized tension-type headaches with superimposed migraine-like attacks. The latter are more frequent, more intense, and longer than any episodic migraine that the patient might have experienced prior to the development of the chronic daily headaches. Rebound presenting as migraine without tension-type pain has been mentioned in a few previous articles on chronic daily headache, but there have been no previous articles stressing that frequent migraine might relate to the analgesics that are being used. These case histories are presented to illustrate that frequent migraine and migraine status without tension-type headaches may be manifestations of rebound and improve when the offending analgesic agents are stopped. If the clinician fails to recognize this unusual presentation of rebound headache, the patient might be placed on unnecessary and often ineffective medications for prophylaxis instead of stopping the offending pain relief medications.

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