Comorbidity of Headache and Depressive Disorders

Cephalalgia ◽  
1999 ◽  
Vol 19 (4) ◽  
pp. 211-217 ◽  
Author(s):  
DD Mitsikostas ◽  
AM Thomas
Keyword(s):  
Migraine With Aura ◽  
Depressive Disorders ◽  
Rating Scales ◽  
Rating Scale ◽  
Primary Headache ◽  
Anxiety And Depression ◽  
Psychiatric Evaluation ◽  
Drug Overuse ◽  
And Gender ◽  
Headache Patients

The goal of the present study was to investigate the clinical profile of patients with primary headache syndromes who also suffer from mood disorders. Four-hundred-and-seventy headache outpatients (170M, 300F) and 150 age- and sex-matched healthy subjects were screened using a specific questionnaire that included the Hamilton rating scales for anxiety and depression. The average scores of the Hamilton rating scales for anxiety and depression were significantly higher in headache sufferers (17.4 and 14.2, respectively) than in healthy people (6.8 and 5.7, respectively). The frequency of headache attacks, the history of headaches, and gender (women more than men) were correlated with the score of the Hamilton rating scale for both anxiety and depression. Sixteen headache patients (3.4%) achieved the DSM-IV criteria for major depression or dysthymia versus one among headache-free subjects (0.6%; OR 5.2). Patients suffering from drug-overuse and migraine with aura showed the higher odds ratios (35 and 17, respectively). These results suggest that those headache patients with long history and high frequency of headaches, or patients suffering from migraine with aura and drug-overuse might benefit from psychiatric evaluation.

EVALUATION OF ANXIETY AND DEPRESSION DISORDERS AND THE ASSOCIATED FACTORS AMONG HEMODIALYSIS SUBJECTS

2019 ◽  
Vol 17 (4) ◽  
pp. 405-416
Author(s):  
Driss Touil ◽  
Mahjoub Aouane ◽  
Ahmed Omar Touhami Ahami
Keyword(s):  
Analytical Study ◽  
Depressive Disorders ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Psychiatric Evaluation ◽  
Average Score ◽  
Dialysis Unit ◽  
Taking Charge ◽  
Depression Disorders ◽  
Anxious State

Identifying anxio-depressive disorders, evaluating their prevalence and determining the different factors that can intervene in their hap- pening to the patients suffering from hemodialysis. Transversal descriptive and analytical study over 70 patients, real- ized at the dialysis unit of the Idrissi regional hospital’s department of medicine at Kenitra, Morocco, over a period of three months starting from 27 March to 26 June 2015. The data were acquired from a survey and psychiatric evaluation scales: The scale HADS (Hospital Anxiety and Depression Scale ) to evaluate anxiety and depression and the scale of « Big Five French Inventory to evaluate the treats of personality» (BF-Fr). Average age was from 54,66±15,96 years. The seniority of the hemodialysis was on average 5,20±3,23 years. The studied traits of personality show a decrease regard to the average score of dimen- sion O (overture of sense) and of the dimension E score (extraversion) versus an evaluation of the dimension N score (Neu ro ticism). The prevalence of anxio-depressive troubles were as the following; 74,29% presented an anxious state (suspected or proven) and 70% had a depressive state (suspected or proven). The anxious troubles were correlated to age and to N and O characters of personality traits BFI-Fr. the depressive troubles were correlated to N charac- ters traits of personality BFI-Fr, and the anxious troubles were pos- itively correlated to depressive troubles. The prevalence of anxio-depressive troubles among hemodialysis subjects was elevated with repercussions on the personality. The involvement of a psychologist in the processes of taking charge is obligatory.

The Relationship Between Anxiety and Depression in Children: Rating Scales and Clinical Variables*

1987 ◽  
Vol 32 (6) ◽  
pp. 433-439 ◽  
Author(s):  
C. Stavrakaki ◽  
B. Vargo ◽  
L. Boodoosingh ◽  
N. Roberts
Keyword(s):  
Depressive Symptoms ◽  
Behavioral Problems ◽  
Rating Scales ◽  
Rating Scale ◽  
Anxiety And Depression ◽  
Clinical Variables ◽  
Observer Ratings ◽  
One Year ◽  
The Relationship ◽  
Depressed Children

The present study examined the relationship between anxiety and depression in children in the context of proposed adult models. The results support the qualitative distinction between anxious and depressed patient groups on subsets of rating scale measures and clinical variables. In contrast to anxious children who were younger, (day patients) had been ill for longer than one year, presented with behavioral problems, and were low on observer ratings of depressive symptoms; depressed children were older, (inpatients) had been ill for less than one year, presented with emotional problems and were high on observer ratings of both anxious and depressive symptoms. The finding that the older depressed children were concurrently anxious while the younger anxious children were not concurrently depressed is discussed from the viewpoint of a hypothesized temporal sequence between anxiety and depression. The implication of this and other related findings are discussed in regard to their importance for differential diagnosis and prognosis.

Prevalence and Gender Differences of ODD, Anxiety, and Depression in a Sample of Children With ADHD

2015 ◽  
Vol 23 (11) ◽  
pp. 1339-1345 ◽  
Author(s):  
Gudlaug Marion Mitchison ◽  
Urdur Njardvik
Keyword(s):  
Gender Differences ◽  
Internalizing Symptoms ◽  
Rating Scale ◽  
Self Report ◽  
Anxiety And Depression ◽  
Children With Adhd ◽  
Behavior Rating Scale ◽  
Oppositional Defiant ◽  
And Gender ◽  
Reported Data

Objective: Studies on comorbidity in children diagnosed with ADHD have relied more on parent/teacher reports instead of self-reported data and have focused on the frequency of comorbid symptoms instead of scores above clinical cutoffs. The purpose of this study was to examine the prevalence of oppositional defiant disorder (ODD), anxiety, and depression in children with ADHD, using self-report measures for internalizing symptoms and parent-reported measures for externalizing symptoms for increased accuracy. Gender differences were also assessed. Method: Parents of 197 children diagnosed with ADHD answered the Disruptive Behavior Rating Scale, and 112 of the children filled out the Multidimensional Anxiety Scale for Children and the Children’s Depression Inventory. Results: Results revealed that 19.28% of the children met cut-off criteria for ODD, 41.96% for anxiety, and 21.43% for depression. Conclusion: Our findings indicate a relatively lower prevalence of ODD and a slightly higher prevalence of anxiety symptoms than previously reported. Possible explanations and future directions are discussed.

scholarly journals Differentiated approach and indications for optimization of agomelatine therapy for endogenous depression

2019 ◽  
Vol 11 (2) ◽  
pp. 71-77
Author(s):  
L. I. Abramova ◽  
G. P. Panteleeva ◽  
I. Yu. Nikiforova ◽  
T. E. Novozhenova
Keyword(s):  
Depressive Disorders ◽  
Rating Scales ◽  
Rating Scale ◽  
Treatment Cycle ◽  
Endogenous Depression ◽  
Good Effect ◽  
Antidepressant Effect ◽  
Antidepressive Effect ◽  
Wide Range ◽  
Days Of Therapy

Objective: to develop and justify differentiated indications for the use of agomelatine (valdoxan) to treat the typological variants of endogenous depressions with varying severity on the basis of an analysis of its therapeutic efficacy.Patients and methods. An open prospective study was conducted using the clinical, psychopathological, and psychometric rating scales: the Hamilton Depression Rating Scale (HAMD-21); Udvalg for Kliniske Undersњgelser Scale (UKU); the Snaith-Hamilton Pleasure Scale (SHAPS) for assessing anhedonic disorders, and statistical methods. Examinations were made in 56 patients (mean age, 34.9 years) with moderate and severe endogenous depression within affective psychosis (n=42) and shift-like schizophrenia (n=14) (ICD-10 items F31.3–4; F32.1–2, and F33.1–2). The patients received a cycle treatment with agomelatine (valdoxan) 25–50 mg once a day in the evening for 4–8 weeks. The patients' status was evaluated over time on fixed days from a reduction in the mean total score (MTS) of the respective scales as insignificant (less than 19% reduction in disorders), moderate (20–49%), good (50–69%), and excellent (70% or more) effects. The effect of agomelatine was analyzed in two patient groups. The specific features of the antidepressive effect and its dynamics in the presence of endogenous depressions of different typologies (melancholic, anxious, and adynamic depressions) were studied in Group 1 (n=26); the effect of agomelatine on anhedonic endogenous depressions and manifestations of anhedonia in different mental activity areas (interests, social activity, emotional engagement and eating/drinking) was investigated in Group 2 (n=30).Results and discussion. There was a good tolerance and a high antidepressant activity of agomelatine during its treatment cycle for moderate and severe endogenous depressions. A significant improvement (an 84.4% reduction in HAMD-21 MTS) was noted in patients at 3 and 4 weeks of the treatment cycle and consistently persisted at a subsequent follow-up. Agomelatine showed a good effect (a 50% or more reduction in HAMD-21 MTS) just at 14 days of therapy. The drug was observed to have a balanced antidepressant effect, significant thymoleptic, stimulant, anxiolytic, and antianhedonic activities (reductions in the MTS of depressive disorders by 90.83, 84.9, 82.39, and 78.9%, respectively).Conclusion. The universal spectrum of the antidepressive effect of agomelatine, its good tolerability, high efficacy, and rapid improvement makes it the drug of choice in treating a wide range of psychopathological endogenous depressions: melancholic, apatho-adynamic, anxious, and anhedonic ones.

Biomarkers of depressive disorders: A multiplex analysis of blood serum

2017 ◽  
Vol 41 (S1) ◽  
pp. S524-S524 ◽  
Author(s):  
A.S. Boiko ◽  
I.S. Losenkov ◽  
L.A. Levchuk ◽  
G.G. Simutkin ◽  
N.A. Bokhan ◽  
...  
Keyword(s):  
Treatment Response ◽  
Depressive Disorders ◽  
Rating Scales ◽  
Rating Scale ◽  
Basic Research ◽  
Serum Markers ◽  
Control Group ◽  
Clinical Indicators ◽  
Feasible Option ◽  
Potential Biomarkers

Depressive disorders are a great burden for individual patients and society. Blood-based biomarkers are regarded as a feasible option for investigation of depressive disorders. Several potential biomarkers for depression were selected. We studied the following serum markers: cortisol, melatonin, brain-derived neurotrophic factor (BDNF), prolactin, insulin-like growth factor 1 (IGF-1), β-endorphin, orexin A. The patient sample consisted of 78 persons with depressive disorders. Patients were divided into two groups: 46 patients with a first depressive episode and 32 patients with recurrent depressive disorder. Control group consisted of 71 healthy individuals of corresponding age and sex. All markers were measured in serum using MILLIPLEX® MAP panels (Merck, Darmstadt, Germany) by analyzer MAGPIX (Luminex, USA). Statistical analyses were performed using SPSS software. Results were expressed as median and quartile intervals [Q1–Q3]. There was a significant increase of serum concentrations of cortisol (663.69 [467.5–959.49] nmol/L, Р < 0.001) and melatonin (66.31 [33.6–132.59] pg/mL, P = 0.029) in patients compared with the control group (526.1 [367,24–654,7] nmol/L and 45.11 [27.47–73.47] pg/mL). In addition, correlations were found between potential biomarkers, clinical indicators and treatment response measured by applying the Hamilton Depression rating scale and the Clinical Global Impression rating scales. A significant correlation was found between the concentration of prolactin and high response to pharmacotherapy (r = –0.267, P = 0.029). Identifying biomarkers that can be used as diagnostics or predictors of treatment response in people with depressive disorders will be an important step towards being able to provide personalized treatment.Disclosure of interestThe work is supported by the project of Russian Foundation of Basic Research No 14-04-01157a.

Features of Formation and System of Psychoprophylaxis of Suicidal Behavior in Young Patients with Depression

2017 ◽  
Vol 41 (S1) ◽  
pp. s239-s239
Author(s):  
H. Kozhyna ◽  
V. Mykhaylov ◽  
K. Zelenskay
Keyword(s):  
Family Therapy ◽  
Suicidal Behavior ◽  
Depressive Episode ◽  
Suicide Risk ◽  
Depressive Disorders ◽  
Rating Scale ◽  
Young Patients ◽  
Clinical Manifestations ◽  
Cognitive Behavioral ◽  
Anxiety And Depression

The work covers the study of the formation of suicidal behavior in young adults with depressive disorders and developing of pathogenetic based system of its prevention. There were clinical and psychopathological signs of depressive disorders in young patients analyzed. Anxiety, asthenia, asthenic-apathetic and melancholy variants of depressive disorders in young patients with suicidal behavior were highlighted. In this study, there were the markers of suicide risk for young patients with depressive disorders determined: high suicide risk, low death self-consciousness, high anhedonia level, clinical manifestations of anxiety and depression by the hospital anxiety and depression scale, severe anxiety and depression by the Hamilton anxiety rating scale, major depressive episode by the Montgomery-Asberg depression rating scale. It has been proved that in observed young patients with depressive disorders with suicide behavior increased concentrations of serotonin, cortisol, noradrenaline and decreased levels of adrenaline and melatonine in plasma were observed. These changes were determined as neurohormonal background for depletion of adaptation resource in stress situations. There were approaches to differentiated prevention of suicidal behavior in depressive disorders in young people validated that include pharmacotherapy (selective SSRI, melatonin, serotonin and norepinephrine), psychotherapy and psychoeducation. Psychotherapeutic complexin patients with depressive episode must include personality-oriented psychotherapy, cognitive behavioral therapy, family therapy and autogenous training; in disorders of adaptation – rational psychotherapy, cognitive-behavioral analytic psychotherapy, family therapy, autogenic training. Psychoeducation should be carried out using information modules, training a positive self-image, improved compliance; formation of communication skills, problem solving, interpersonal interaction and problem-oriented discussions.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Use of Headache Rating Scales: A Multiaxial Approach

Cephalalgia ◽  
1986 ◽  
Vol 6 (2) ◽  
pp. 69-80 ◽  
Author(s):  
P Bech ◽  
M Kastrup ◽  
D Loldrup
Keyword(s):  
Rating Scales ◽  
Rating Scale ◽  
Diagnostic System ◽  
Psychosocial Stressors ◽  
Anxiety And Depression ◽  
Future Research ◽  
Basic Principles ◽  
The Core ◽  
Core Symptoms

The basic principles of the rating scale procedure have been outlined, including the Likert scale, the Guilford criteria for item definitions, and the Guttman and Rasch criteria for item combinations. With these criteria, headache rates among the core symptoms of anxiety and depression. Next, we have discussed one of the prevailing scales for headache, the Waters Headache Questionnaire (WHQ), with a multiaxial approach. The WHQ thus contains a severity axis, a diagnostic axis, and a personality axis. Previous studies on the validity of the WHQ, including factor analysis, have shown that migraine and muscular headaches are not mutually exclusive categories. Studies to validate a two-dimensional diagnostic system of migraine and non-migraine headache by Rasch models are discussed. In the field of personality it was suggested, when using questionnaires like the WHQ, to focus on the concepts of acquiescence and dissimulation. Supplemental axes such as “severity of psychosocial stressors” and “social functioning” or “quality of life” should be considered in future research.

scholarly journals Developing a Brief Behavior Rating Scale for Progress Monitoring of Depression in School Settings

2018 ◽  
Vol 45 (3) ◽  
pp. 163-172 ◽  
Author(s):  
Evan H. Dart ◽  
Prerna Arora ◽  
Tai Collins ◽  
Kevin Stark ◽  
Clayton R. Cook ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Depressive Disorders ◽  
Rating Scales ◽  
Progress Monitoring ◽  
Rating Scale ◽  
Response To Treatment ◽  
Behavior Rating ◽  
Behavior Rating Scale ◽  
Monitoring Tools ◽  
Data Driven Decisions

Frequent formative assessment of students’ functioning, or progress monitoring, is a critical component of multi-tiered systems of support as data inform data-driven decisions about response to treatment. Progress monitoring tools for students’ academic and behavioral functioning are readily available and widely researched; however, despite the documented prevalence of depressive disorders among youth and that schools have been put forth as an ideal location for the delivery of mental health services, there are currently no progress monitoring tools to examine students’ response to interventions that target depression. To address this gap, this study sought to develop a progress monitoring assessment of students’ depressive symptoms using an empirically informed model for creating Brief Behavior Rating Scales (BBRS). Using this model, a four-item BBRS of depressive symptoms (BBRS-D) was created from the item pools of the Beck Depression Inventory for Youth (BDI-Y) and Children’s Depression Inventory (CDI) administered during a treatment study of depression in female youth; the resulting short scale corresponds well to the full-length assessments (i.e., r = .65 and r = .59); however, the BBRS-D possessed lower than adequate internal consistency (α = .50) and test–retest reliability ( r = .56). Limitations and future directions are discussed.

scholarly journals The Validity of the Hospital Anxiety and Depression Scale and the Geriatric Depression Scale in Parkinson’s Disease

2006 ◽  
Vol 17 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Federica Mondolo ◽  
Marjan Jahanshahi ◽  
Alessia Granà ◽  
Emanuele Biasutti ◽  
Emanuela Cacciatori ◽  
...  
Keyword(s):  
Rating Scales ◽  
Rating Scale ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Geriatric Depression ◽  
Operating Characteristics ◽  
Hospital Anxiety ◽  
Predictive Values ◽  
Face Scale

We assessed the concurrent validity of the Hospital Anxiety and Depression Scale (HADS) and the Geriatric Depression Scale (GDS) against the Hamilton Rating Scale for Depression (Ham-D) in patients with Parkinson’ disease (PD). Forty-six non-demented PD patients were assessed by a neurologist on the Ham-D. Patients also completed four mood rating scales: the HADS, the GDS, the VAS and the Face Scale. For the HADS and the GDS, Receiver Operating Characteristics (ROC) curves were obtained and the positive and negative predictive values (PPV, NPV) were calculated for different cut-off scores. Maximum discrimination between depressed and non-depressed PD patients was reached at a cut-off score of 10/11 for both the HADS and the GDS. At the same cut-off score of 10/11 for both the HADS and the GDS, the high sensitivity and NPV make these scales appropriate screening instruments for depression in PD. A high specificity and PPV, which is necessary for a diagnostic test, was reached at a cut-off score of 12/13 for the GDS and at a cut-off score of 11/12 for the HADS. The results indicate the validity of using the HADS and the GDS to screen for depressive symptoms and to diagnose depressive illness in PD.

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