Features of Formation and System of Psychoprophylaxis of Suicidal Behavior in Young Patients with Depression

2017 ◽  
Vol 41 (S1) ◽  
pp. s239-s239
Author(s):  
H. Kozhyna ◽  
V. Mykhaylov ◽  
K. Zelenskay
Keyword(s):  
Family Therapy ◽  
Suicidal Behavior ◽  
Depressive Episode ◽  
Suicide Risk ◽  
Depressive Disorders ◽  
Rating Scale ◽  
Young Patients ◽  
Clinical Manifestations ◽  
Cognitive Behavioral ◽  
Anxiety And Depression

The work covers the study of the formation of suicidal behavior in young adults with depressive disorders and developing of pathogenetic based system of its prevention. There were clinical and psychopathological signs of depressive disorders in young patients analyzed. Anxiety, asthenia, asthenic-apathetic and melancholy variants of depressive disorders in young patients with suicidal behavior were highlighted. In this study, there were the markers of suicide risk for young patients with depressive disorders determined: high suicide risk, low death self-consciousness, high anhedonia level, clinical manifestations of anxiety and depression by the hospital anxiety and depression scale, severe anxiety and depression by the Hamilton anxiety rating scale, major depressive episode by the Montgomery-Asberg depression rating scale. It has been proved that in observed young patients with depressive disorders with suicide behavior increased concentrations of serotonin, cortisol, noradrenaline and decreased levels of adrenaline and melatonine in plasma were observed. These changes were determined as neurohormonal background for depletion of adaptation resource in stress situations. There were approaches to differentiated prevention of suicidal behavior in depressive disorders in young people validated that include pharmacotherapy (selective SSRI, melatonin, serotonin and norepinephrine), psychotherapy and psychoeducation. Psychotherapeutic complexin patients with depressive episode must include personality-oriented psychotherapy, cognitive behavioral therapy, family therapy and autogenous training; in disorders of adaptation – rational psychotherapy, cognitive-behavioral analytic psychotherapy, family therapy, autogenic training. Psychoeducation should be carried out using information modules, training a positive self-image, improved compliance; formation of communication skills, problem solving, interpersonal interaction and problem-oriented discussions.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Clinical specifics of stress-related disorders in volunteers whose activities are related to Joint Forces Operation

2021 ◽  
Vol 10 (45) ◽  
pp. 141-147
Author(s):  
H.M. Kozhyna ◽  
K.O. Zelenska ◽  
V.V. Viun ◽  
M.M. Khaustov ◽  
Yu.O. Asieieva
Keyword(s):  
Traumatic Stress ◽  
Depressive Episode ◽  
Rating Scale ◽  
Stress Disorder ◽  
Traumatic Event ◽  
Clinical Manifestations ◽  
Stress Disorders ◽  
Anxiety And Depression ◽  
Post Traumatic Stress ◽  
Hamilton Anxiety

A volunteer movement has emerged in Ukraine during the Revolution of Dignity and the events that followed it. Experts consider this event as an important component of civil society and the main driving force of the country’s reform. The clinical structure of post-stress disorders among examined volunteers was represented by the following nosologic forms: F 43.2 adjustment disorders (32.7% of men and 28.1% of women), F 43.1 - post-traumatic stress disorder (27.6% of men and 22.9% of women), F 41.0 - panic disorder (22.4% of men and 29.1% of women), F 41.1 - generalized anxiety disorder (17.3% of men and 19.9% of women). According to the Scale of Severity of Traumatic Stress, 62.8% of respondents have complete manifestation and 37.2% clear manifestation of stress disorder. According to the Hamilton Anxiety and Depression Rating Scale, 56.2% of subjects had a severe depressive episode, 62.1% had severe anxiety episode, 42.3% had moderate depressive episode, and 33.4% had a moderate anxiety episode. Severe clinical manifestations of PTSD were characteristic of volunteers who survived the fighting, with a high level of exposure to the traumatic event on all PTSD scales; excessive signs of stress disorder, severe or moderate depressive and anxiety episodes by the Hamilton Anxiety and Depression Rating Scale.

scholarly journals Modern depressive disorder phenomena associated with suicidal male behavior

2020 ◽  
Vol 86 (1) ◽  
pp. 46-50
Author(s):  
G. Koltsova
Keyword(s):  
Suicidal Behavior ◽  
Depressive Disorders ◽  
Severe Depression ◽  
Main Group ◽  
Anxiety And Depression ◽  
Control Group ◽  
Self Awareness ◽  
Comprehensive Survey ◽  
High Level ◽  
Severe Anxiety

It was conducted a comprehensive survey of 100 men with depressive disorders. The clinical, psychopathological and pathopsychological features of depressive disorders associated with suicidal behavior in men were analyzed. All subjects were divided into two groups: the main group consisted of 51 patients with signs of suicidal behavior, control group consisted of 49 patients without signs of suicidal behavior. It has been shown that the clinical structure of depressive disorders is presented by sad (in 35.5 % of patients in the main group and in 34.7 % of control group), emotionally labile (in 29.9 % and in 31.3 %, respectively) and apathetic (in 34.6 % and in 34.0 %) variants. It has been established, that men with depressive disorders associated with self-destructive behavior have a high level of suicidal risk, low self-awareness of death, major or moderate depressive episode by MADRS, severe depression by HAM-D, clinically severe anxiety and depression by HADS, presence of serious suicidal intentions on the Columbian scale. Suicidogenic factors in men with depressive disorders are frustration of basic needs, loss of targeted personality installations and alcohol consumption. Keywords: depressive disorders, depression, anxiety, suicidal behavior.

scholarly journals Predictors of a suicidal behavior in patients with dementia

2017 ◽  
Vol 41 (S1) ◽  
pp. S399-S399
Author(s):  
N. Maruta ◽  
I. Mudrenko
Keyword(s):  
Suicidal Behavior ◽  
Suicide Risk ◽  
Rating Scale ◽  
Cognitive Disorders ◽  
Severe Depression ◽  
Control Group ◽  
Self Awareness ◽  
Wide Range ◽  
Significant Difference ◽  
High Level

IntroductionCognitive disorders are associated with a wide range of psychopathological syndromes and behavioral disorders, and suicidal manifestations in dementia are understudied nowadays.ObjectivesTo investigate clinical-psychopathological predictors of a suicidal behavior in patients with dementia.MethodologyForty-four patients with dementia were examined: 23 patients with suicidal manifestations and 21 patients without them (control group). Clinical and psychometrical methods were used: Mini Mental State Examination (MMSE) scale; Assessment of Suicide Risk scale; Hamilton Rating Scale for Depression (HDRS), and statistical ones.ResultsIt was determined that male patients with dementia had suicidal behavioral manifestations more often than female patients (69.6%; P < 0.05). An average age of the patients was 69.88 ± 1.85 years with no significant difference between the main and control groups.The majority of the patients with dementia (52.3%) had suicidal manifestations. Real suicidal intentions were the most frequent (25%; P < 0.05); 20.5% of patients expressed passive thoughts (anti-vital sentences, fantasies, ideas concerning death); 2 patients (6.82%; P < 0.05) had suicidal attempts. Patients with suicidal tendencies in their clinical picture more often had hallucinatory syndrome (39.1%; P < 0.05); features of severe depression (35.04 ± 1.54 points; P < 0.01); a high level of suicidal risk (26.34 ± 1.68 points; P < 0.01); a severe cognitive deficit (ММSE score 0–10); and a significantly lower level of self-awareness of death (18.53 ± 0.72 points; P < 0.05) in comparison with the control group.ConclusionsA high suicide risk in dementia correlated with a level of depressive symptoms (r = 0.6), moderate and/or severe grades of dementia (r = 0.45), and a low level of self-awareness of death (r = 0.35).Disclosure of interestThe authors have not supplied their declaration of competing interest.

Anxiety-depressive disorders in children: Neurobiological and neurohormonal aspects

2017 ◽  
Vol 41 (S1) ◽  
pp. S455-S455
Author(s):  
P.T. ◽  
E. Mykhailova ◽  
T. Matkovska ◽  
N. Reshetovska ◽  
A. Goloborodko
Keyword(s):  
Suicidal Behavior ◽  
Depressive Disorders ◽  
Prognostic Significance ◽  
Brain Dysfunction ◽  
Early Ontogeny ◽  
Anxiety And Depression ◽  
Melatonin Level ◽  
Serotonin Level ◽  
Early Puberty ◽  
Competing Interest

ObjectiveThe need for diagnosis and correct classification of depression among children is dictated by its burdeness with age, high risk of recurrence at further stages of child development and propensity to suicidal behavior.Materials and methodsOne hundred and sixty adolescents with ADD were included in our study. The study design comprised: clinicopsychopathological, somatoneurological, psychological and neurohormonal methods.ResultsClustering symptom of anxiety and depression have shown that for children in early puberty is typical more formation of somatic (35.2%), behavioral (21.6%), phobic (21.6%) variants of depression, less-anxiety (13.5%), asthenia (8.1%). For children in puberty – apathetic (30.1%), anxiety (28.9%), dismorfofobic (27.7%), behavioral (13.3%) variants. The proportion of suicidal behavior of depression increases in proportion to age, mainly due to suicidal thoughts, sayings, auto-aggressive behavior. Analysis of the formation conditions of anxiety and depression in children showed a significant correlation of genetic, biological and socio-environmental components.Symptoms of the minimal brain dysfunction (MBD) at an early ontogeny (prognostic value = +4.8), loaded natal period (PV = +4.2), frequent colds in the medical history (PV = 3.7), signs of cerebro-organic failure (PV = +3.8) and obesity as an endocrine disorder (PV = +2.1), sex and age of the manifestation of the first depressive episode in the early stages ontogenesis in boys aged 7 years (PS = +5.3), in girls aged 9 years (PS = +3.9) have been registered among biological risk factors for the ADD formation. Prognostic significance of neurohormonal parameters as regards the risk for ADD formation in adolescents is based on a decreased serotonin level in patients with depressive anxiety (PV = +2.8) and a reduced melatonin level, irrespective of the variant of clinical depression (PV = +2.4).ConclusionDetermination of neurobiological and neurohormonal risk markers for the development of the ADD makes it possible to carry out psychoprophylactic measures.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Predictors of clinical response after rTMS treatment of patients suffering from drug-resistant depression

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Aurélie Lacroix ◽  
Benjamin Calvet ◽  
Benjamin Laplace ◽  
Marilyne Lannaud ◽  
Brigitte Plansont ◽  
...  
Keyword(s):  
Clinical Response ◽  
Clinical Improvement ◽  
Depressive Episode ◽  
Depressive Disorders ◽  
Rating Scale ◽  
Routine Practice ◽  
Drug Resistant ◽  
Therapeutic Choice ◽  
Resistant Depression ◽  
Success Of Treatment

AbstractRepeated transcranial magnetic stimulation (rTMS) is a therapeutic brain-stimulation technique that is particularly used for drug-resistant depressive disorders. European recommendations mention the effectiveness of 30 to 64%. The failure rate of treatment is high and clinical improvement is visible only after a certain period of time. It would thus be useful to have indicators that could anticipate the success of treatment and more effectively guide therapeutic choices. We aimed to find predictive indicators of clinical improvement at 1 month after the start of rTMS treatment among the data collected during the care of patients with drug-resistant depression included in the Neuromodulation Unit of the Esquirol Hospital in Limoges since 2007. In total, 290 patients with a pharmaco-resistant depressive episode, according to the Hamilton Depression Rating Scale (HDRS) (score ≥8), before treatment who underwent a complete course of rTMS treatment and did not object to the use of their collected data were included. The clinical response in routine practice, corresponding to a decrease in the HDRS score of at least 50% from inclusion, was determined and complemented by interquartile analysis. A combination of factors predictive of clinical response during care, such as a short duration of the current depressive episode associated with a higher HDRS agitation item value (or a lower perceived sleepiness value) and a higher number of previous rTMS treatments, were identified as being useful in predicting the efficacy of rTMS treatment in routine clinical practice, thus facilitating the therapeutic choice for patients with drug-resistant depression.

scholarly journals Emotions as a state and as a trait in people with depressive disorders*

2019 ◽  
Vol 73 ◽  
pp. 721-728
Author(s):  
Aleksandra Skiba ◽  
Paulina Maruszewska ◽  
Monika Talarowska ◽  
Piotr Gałecki
Keyword(s):  
Psychosocial Functioning ◽  
Depressive Episode ◽  
Positive Emotions ◽  
Depressive Disorders ◽  
Rating Scale ◽  
Negative Emotions ◽  
Healthy People ◽  
Control Group ◽  
The People ◽  
Positive And Negative Emotions

Depression is a disorder involving a number of changes in human psychosocial functioning. The aim of this study is to evaluate the intensity of positive and negative emotions understood both as a state and a permanent personality trait in people with depressive disorders and to determine whether the intensity of positive and negative emotions differentiates healthy people from people suffering from depressive disorders. The study was conducted on 107 individuals – 67 people from the experimental group suffering from depressive disorders and 40 people from the control group with a negative interview in terms of mental and somatic disorders. The following tools were used: Hamilton Depression Rating Scale (evaluation of severity of depressive symptoms), STAI Questionnaire (evaluation of anxiety severity as a state and trait) and PANAS Questionnaire (intensity of negative and positive emotions as a state and trait). A significantly higher intensity of positive emotions understood both as a state and a trait was observed in the people not suffering from depression, while the opposite results were obtained with regard to negative emotions, i.e. the individuals suffering from depression recorded lower scores than the healthy persons. It was also shown that the people with depression had higher scores in terms of the level of anxiety as a state and trait. The intensity of positive emotions as a state was significantly higher among the people with the first depressive episode in comparison to the people with recurrent depressive disorders. The severity of depression correlated positively with the intensity of negative emotions as a state both at the time of inclusion in the study and after obtaining a response to the applied pharmacological treatment. Experienced positive and negative emotions, understood both as a state and as a trait, differentiate not only individuals with depression from healthy people, but also patients with the first depressive episode and those with recurrent depressive disorders.

scholarly journals Predictors of suicidal behavior in patients with cognitive impairments in depressive disorders

2020 ◽  
Vol 24 (4 (96)) ◽  
pp. 58-64
Author(s):  
N. Maruta ◽  
S. Yaroslavtsev
Keyword(s):  
Cognitive Impairment ◽  
Depressive Disorder ◽  
Interpersonal Relationships ◽  
Suicidal Behavior ◽  
Cognitive Functions ◽  
Affective Disorders ◽  
Suicide Risk ◽  
Depressive Disorders ◽  
Bipolar Affective Disorder ◽  
Autonomic Disorders

The aim of the study was to determine predictors of suicide risk in patients with cognitive impairment in depressive disorders.Material and methods. 362 patients with cognitive impairment in depressive disorders were examined: 123 patients with recurrent depressive disorder, 141 patients with bipolar affective disorder and 98 patients with prolonged depressive reaction. A set of research methods was used to study the factors of suicidal behavior in patients with cognitive impairment in depressive disorders: clinical-psychopathological, psychodiagnostic (questionnaire "Self-assessment of the severity of autoaggressive predictors") and mathematical-statistical. Results of the research. Predictors of suicide risk in patients with cognitive impairment in depressive disorders were identified. The moderate level of autoaggression and aggression, low level of impulsivity, high and severe narrowing of cognitive functions, severe narrowing of interpersonal relationships, severity of affective disorders, moderate and severe autonomic disorders were identified in patients with recurrent depressive disorder. Pronounced and moderate level of autoaggression, aggression and impulsivity, high and pronounced level of narrowing of cognitive functions, pronounced narrowing of interpersonal relationships, severity of affective disorders, moderate and severe level of autonomic disorders were identified in patients with bipolar affective disorder. Moderate levels of autoaggression and narrowing of cognitive functions, low levels of aggression, severe impulsivity, affective disorders and narrowing of interpersonal relationships, and high levels of autonomic disorders were identified in patients with prolonged depressive reaction.Conclusions. As a result of the study, the features of suicidal behavior in patients with cognitive impairment in depressive disorders were identified. It can act as diagnostic criteria and predictors of suicidal behavior in differential diagnostics and could take into account when creating psychocorrectional programs aimed at reducing suicidal risk in patients with cognitive dysfunctions in depressive disorders.

scholarly journals THE RELATIONSHIP OF QUALITY OF LIFE INDICATORS AND PSYCHOLOGICAL STATUS FEATURES IN CADETS OF THE UFA LAW INSTITUTE OF THE MINISTRY OF INTERNAL AFFAIRS OF THE RUSSIAN FEDERATION WITH CHRONIC GENERALIZED CATARRHAL GINGIVITIS

2020 ◽  
Vol 16 (3) ◽  
pp. 66-73
Author(s):  
Olesya Sitdikova ◽  
Milyausha Kabirova ◽  
Oksana Gubina
Keyword(s):  
Quality Of Life ◽  
Physical Health ◽  
Social Life ◽  
Depressive Disorders ◽  
Negative Impact ◽  
Clinical Manifestations ◽  
Well Being ◽  
Psychological Status ◽  
Anxiety And Depression

Subject. Chronic generalized catarrhal gingivitis affects the physical condition of a person, as well as the psychology of their behavior, emotional reactions, as well as their role in social life. Doctors are not always set up to assess the quality of life and patient satisfaction with the therapy. The peculiarity of this disease is the vastness of its clinical manifestations, and the need to start treatment in a timely manner, and patients taking medications themselves, affects poor adherence to treatment. These characteristics have an impact on the quality of life, and if the quality of life improves as a result of therapy, this motivates patients to effectively control their condition. Goal ― to assess the quality of life, frequency and severity of anxiety and depressive disorders in cadets with chronic generalized catarrhal gingivitis. Methodology. We conducted a survey of 140 cadets aged 18 to 25 years. Results.The revealed patterns suggest that bleeding, gum pain,and halitosis often contribute to the clinical manifestation of anxiety and depressive disorders in cadets with chronic generalized catarrhal gingivitis, thereby impairing the quality of life. The combination of various metabolic factors in a closed circle mutually increases the severity of not only clinical manifestations of chronic generalized catarrhal gingivitis, but also affects the mental status of the patient, increasing the degree of neurosis-like manifestations Conclusion. Chronic generalized catarrhal gingivitis significantly affects the decline in indicators of not only physical health, but also mental well-being. High levels of anxiety and depression are most significantly correlated with indicators of mental and physical health of cadets . Thus, anxiety and depression of a somatogenic nature has a negative impact on the quality of life, aggravates the course of the underlying disease, significantly affecting the General well-being of the patient.

Frontal Motor Cortex Activity During Reactive Control Is Associated With Past Suicidal Behavior in Recent-Onset Schizophrenia

Crisis ◽  
2015 ◽  
Vol 36 (5) ◽  
pp. 363-370 ◽  
Author(s):  
Michael J. Minzenberg ◽  
Tyler Lesh ◽  
Tara Niendam ◽  
Jong H. Yoon ◽  
Yaoan Cheng ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Suicidal Behavior ◽  
Suicide Risk ◽  
Primary Motor Cortex ◽  
Rating Scale ◽  
Premotor Cortex ◽  
Neural System ◽  
Reactive Control ◽  
Recent Onset ◽  
Severity Rating

Abstract. Background: Suicide is prevalent in schizophrenia (SZ), yet the neural system functions that confer suicide risk remain obscure. Circuits operated by the prefrontal cortex (PFC) are altered in SZ, including those that support reactive control, and PFC changes are observed in postmortem studies of heterogeneous suicide victims. Aims: We tested whether history of suicide attempt is associated with altered frontal motor cortex activity during reactive control processes. Method: We evaluated 17 patients with recent onset of DSM-IV-TR-defined SZ using the Columbia Suicide Severity Rating Scale and functional magnetic resonance imaging during Stroop task performance. Group-level regression models relating past suicidal behavior to frontal activation controlled for depression, psychosis, and impulsivity. Results: Past suicidal behavior was associated with relatively higher activation in the left-hemisphere supplementary motor area (SMA), pre-SMA, premotor cortex, and dorsolateral PFC, all ipsilateral to the active primary motor cortex. Conclusion: This study provides unique evidence that suicidal behavior in patients with recent-onset SZ directly relates to frontal motor cortex activity during reactive control, in a pattern reciprocal to the relationship with proactive control found previously. Further work should address how frontal-based control functions change with risk over time, and their potential utility as a biomarker for interventions to mitigate suicide risk in SZ.

Suicide Risk in Outpatients with Specific Mood and Anxiety Disorders

Crisis ◽  
2003 ◽  
Vol 24 (3) ◽  
pp. 105-112 ◽  
Author(s):  
Andrea P. Chioqueta ◽  
Tore C. Stiles
Keyword(s):  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Depressive Episode ◽  
Suicide Risk ◽  
Depressive Disorders ◽  
Major Depressive Episode ◽  
Suicide Ideation ◽  
Anxiety Symptoms ◽  
Major Depressive ◽  
Special Relevance

Summary: The present study examined the relationships between specific anxiety, mood disorders, levels of hopelessness, and suicide ideation. The sample consisted of 606 outpatients recruited from several psychiatric settings. It was found that dysthymia was significantly associated with hopelessness. Patients presenting major depressive episode with higher anxiety symptoms had significantly increased scores on the hopelessness scale. Major depressive episode and bipolar disorder, but not dysthymia, were significantly associated with higher levels of suicide ideation. Increased levels of anxiety symptoms in patients with dysthymia were associated with increased levels of suicide ideation, while increased depressive symptoms in patients with specific phobia and generalized anxiety disorder were associated with significantly lower levels of suicide ideation. The findings suggest that depressive disorders, but not anxiety disorders, constitute risk for suicide. Moreover, the differentiation between a depressive and an anxiety disorder as the principal diagnosis, as well as the assessment of anxiety-level symptoms in patients with major depressive episode and dysthymia, seems of special relevance when assessing suicide risk.

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