The Lactating Breast: MRI Findings and Literature Review

Background: Immunosuppressive therapy is a risk factor for lymphoproliferative disorders. We present a case of primary CNS B-cell lymphoma in the setting of iatrogenic immunosuppression from azathioprine usage. A literature review is provided. Methods: Case report Results: 64-year-old male presents with several weeks of cognitive decline, impaired speech, and headache with a history of ulcerative colitis (on azathioprine and 5-ASA) with no radiological evidence of systemic malignancy. MR showed left frontal extra-axial mass (4.0 x 2.4 x 4.0 cm) with heterogeneous enhancement of a solid component with local dural thickening. The enhancing mass had solid and cystic components. Radiological differential included dural metastasis, atypical meningioma or unusual intra-axial mass including GBM with some dural involvement. He underwent surgical resection, which showed a primary CNS lymphoma, diffuse large B-cell, CD 20 + and EBV +. Post-operatively his cognition improved. Azathioprine was stopped and 5-ASA was increased. He proceeded with MPVC (methotrexate, procarbazine, vincristine, and cytarabine) chemotherapy. Conclusions: Our case shows isolated extra-nodal CNS manifestation of lymphoma in the context of immunosuppressive medications with strikingly atypical MR findings leading to a pre-operative diagnostic dilemma. Treatment is challenging and needs to be individually tailored due to a need for stopping immunosuppressive agents in conjunction with CNS lymphoma treatment.

Download Full-text

Progressive Transformation of Germinal Centers in Presacral Space: MRI Findings and Literature Review

Investigative Magnetic Resonance Imaging ◽

10.13104/imri.2017.21.1.56 ◽

2017 ◽

Vol 21 (1) ◽

pp. 56

Author(s):

Sung Tae Hwang ◽

Deuk Jae Sung ◽

Ki Choon Sim ◽

Na Yeon Han ◽

Beom Jin Park ◽

...

Keyword(s):

Literature Review ◽

Germinal Centers ◽

Presacral Space ◽

Mri Findings

Download Full-text

The accuracy of incremental pre-operative breast MRI findings – Concordance with histopathology in the Swedish randomized multicenter POMB trial

European Journal of Radiology ◽

10.1016/j.ejrad.2019.03.005 ◽

2019 ◽

Vol 114 ◽

pp. 185-191 ◽

Cited By ~ 1

Author(s):

Anders Karlsson ◽

Virginia Gonzalez ◽

Sara Jonmarker Jaraj ◽

Matteo Bottai ◽

Kerstin Sandelin ◽

...

Keyword(s):

Breast Mri ◽

Mri Findings

Download Full-text

Eosinophilic Otitis Media: CT and MRI Findings and Literature Review

Korean Journal of Radiology ◽

10.3348/kjr.2012.13.3.363 ◽

2012 ◽

Vol 13 (3) ◽

pp. 363 ◽

Cited By ~ 7

Author(s):

Won Jung Chung ◽

Jeong Hyun Lee ◽

Hyun Kyung Lim ◽

Tae Hyun Yoon ◽

Kyung Ja Cho ◽

...

Keyword(s):

Literature Review ◽

Otitis Media ◽

Mri Findings ◽

Ct And Mri

Download Full-text

Influence of preoperative MRI on the surgical management of patients with operable breast cancer

Journal of Clinical Oncology ◽

10.1200/jco.2007.25.18_suppl.613 ◽

2007 ◽

Vol 25 (18_suppl) ◽

pp. 613-613 ◽

Cited By ~ 1

Author(s):

M. W. Braun ◽

M. Pölcher ◽

S. Schrading ◽

O. Zivanovic ◽

T. Kowalski ◽

...

Keyword(s):

Breast Cancer ◽

Surgical Management ◽

Clinical Management ◽

Menopausal Status ◽

Breast Mri ◽

Breast Ultrasound ◽

Operable Breast Cancer ◽

Tumor Characteristics ◽

Mri Findings ◽

The Impact

613 Background: To evaluate the impact of preoperative magnetic resonance imaging (MRI) of the breast on the clinical management of patients with operable breast cancer (BC). Methods: Retrospective analysis of 160 patients with operable breast cancer (stages Tis, through T4), who were treated from 2002 through 2004. All patients underwent a full mammographic assessment, high frequency breast ultrasound, and breast MRI. The impact of preoperative MRI was evaluated for each patient with regard to changes in the therapeutic procedure. Patient and tumor characteristics were analysed to identify possible patient subgroups that predominantly benefit from preoperative MRI. Results: Preoperative MRI affected the clinical management in 44 of 160 patients (27.5%). In 30 cases (18.75%) additional in-situ or invasive cancers or a more widespread tumor extent were diagnosed correctly which went undetected by clinical palpation, mammography, and breast ultrasound. In 14 cases (8.75%) additional, surgical procedures were performed based on suspicious MRI findings with benign pathology. Age, menopausal status, breast density, tumor characteristics (type, tumor size, grading), ER-, PR- and HER2- receptor features did not significantly differ between patients in which breast MRI affected the clinical management and patients that experienced no additional information from MRI. Conclusions: Preoperative breast MRI changes surgical management in a considerable amount of patients with operable breast cancer. MRI detects additional invasive carcinoma and proves to be a meaningful supplement to the conventional work-up in the clinical management of breast cancer. This benefit is independent from patients and tumor characteristics. No significant financial relationships to disclose.

Download Full-text

3–5 BI-RADs Microcalcifications: Correlation between MRI and Histological Findings

ISRN Oncology ◽

10.5402/2011/643890 ◽

2011 ◽

Vol 2011 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Valeria Fiaschetti ◽

Chiara Adriana Pistolese ◽

Tommaso Perretta ◽

Elsa Cossu ◽

Chiara Arganini ◽

...

Keyword(s):

Predictive Value ◽

Breast Imaging ◽

Breast Mri ◽

Data Systems ◽

Mri Findings ◽

Day Range ◽

Contrast Enhanced ◽

Malignant Lesions ◽

Stereotactic Vacuum Assisted Biopsy ◽

Sensitivity Specificity

Purpose. To evaluate the correlation between MRI and histopathological findings in patients with mammographically detected 3–5 BI-RAD (Breast Imaging Reporting And Data Systems) microcalcifications and to allow a better surgical planning. Materials and Method. 62 female Patients (age ) with screening detected 3–5 BI-RAD microcalcifications underwent dynamic 3 T contrast-enhanced breast MRI. After 30-day (range 24–36 days) period, 55 Patients underwent biopsy using stereotactic vacuum-assisted biopsy (VAB), 5 Patients underwent stereotactic mammographically guided biopsy, and 2 Patients underwent MRI-guided VAB. Results. Microhistology examination demonstrated 36 malignant lesions and 26 benign lesions. The analysis of MRI findings identified 8 cases of MRI BI-RADS 5, 23 cases of MRI BI-RADS 4, 11 cases of MRI BI-RADS 3, 4 cases type A and 7 cases type B, and 20 cases of MRI BI-RADS 1-2. MRI sensitivity, specificity, positive predictive value, and negative predictive value were 88.8%, 76.9%, 84.2%, and 83.3%, respectively.

Download Full-text

Granular cell tumour of the breast: MRI findings and review of the literature

British Journal of Radiology ◽

10.1259/bjr/95130566 ◽

2007 ◽

Vol 80 (960) ◽

pp. 970-974 ◽

Cited By ~ 28

Author(s):

A M Scaranelo ◽

K Bukhanov ◽

P Crystal ◽

A M Mulligan ◽

F P O'Malley

Keyword(s):

Breast Mri ◽

Granular Cell ◽

Cell Tumour ◽

Granular Cell Tumour ◽

Review Of The Literature ◽

Mri Findings

Download Full-text

Radiological manifestations of chondromyxoid fibroma in the zygoma: A case report and literature review

BJR|case reports ◽

10.1259/bjrcr.20210008 ◽

2021 ◽

pp. 20210008

Author(s):

Atefeh Zeinoddini ◽

Amy Bezold ◽

Obadah Ezzeldin ◽

Huda AL Jadiry

Keyword(s):

Literature Review ◽

Age Group ◽

Benign Bone Tumor ◽

Chondromyxoid Fibroma ◽

Mri Findings ◽

Diagnostic Challenge ◽

Radiological Features ◽

Comprehensive Literature Review ◽

Paediatric Case ◽

Paediatric Age

Chondromyxoid fibroma (CMF) is a rare benign bone tumor of cartilaginous origin, with an extremely rare craniofacial occurrence. Considering its rarity, craniofacial CMF presents a diagnostic challenge for radiologists. To our knowledge, only seven cases of zygomatic CMF have been described in the literature, only one of which was in the paediatric age group. Furthermore, none of the currently reported cases include MRI findings of zygomatic CMF. Here, we present a paediatric case of CMF of the zygoma with a comprehensive literature review of the reported cases, focusing on their radiological features and its differential diagnosis.

Download Full-text

Breast Magnetic Resonance Imaging of Multicentric, Multifocal and Bilateral Cancer — A Case-based Review

European Oncology & Haematology ◽

10.17925/eoh.2011.07.01.24 ◽

2011 ◽

Vol 07 (01) ◽

pp. 24

Author(s):

Virginia Pérez Dueñas ◽

María Ruíz de Gopegui Andreu ◽

Sara Morón Hodge ◽

Asunción Suárez Manrique ◽

◽

...

Keyword(s):

Breast Cancer ◽

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

False Positive ◽

Breast Magnetic Resonance Imaging ◽

Breast Mri ◽

Resonance Imaging ◽

Mri Findings ◽

Mri Features ◽

Breast Magnetic Resonance

Multifocal or multicentric breast cancer can be difficult to detect on mammography or ultrasound, particularly in patients with dense breast tissue. A multimodality approach that includes breast magnetic resonance imaging (MRI) is indicated, particularly when conservative surgery is being considered as it is the most sensitive technique for identifying additional sites of disease. However, its influence on recurrence and survival rates has yet not been clearly established, and false-positive cases may lead to more aggressive management and treatment. Radiologists should therefore be aware of relevant breast MRI findings. Infiltrating carcinomas, contralateral unsuspected carcinomas, occult carcinomas, false-positive cases and post-chemotherapy changes. Several cases of multiple-site breast carcinomas and their corresponding mammographic, ultrasound and MRI features have been reviewed for this article, in which the definition and differences between multifocal, multicentric and contralateral breast carcinoma are explained and the most relevant imaging findings on MRI are illustrated and correlated with mammogram and ultrasound findings. Finally, the role of breast MRI in the pre-operative assessment of breast cancer is discussed.

Download Full-text