scholarly journals Analysis of the intensity of post-vaccination immunity to acute respiratory viral infections of cattle

2021 ◽  
Vol 36 ◽  
pp. 06047
Author(s):  
E.V. Maksimova ◽  
E.S. Klimova ◽  
E.A. Merzlyakova ◽  
L.L. Maksimov
Keyword(s):  
Blood Serum ◽  
Viral Infections ◽  
Live Weight ◽  
Serum Samples ◽  
Post Vaccination ◽  
Diagnostic Center ◽  
Udmurt Republic ◽  
Respiratory Viral Infections ◽  
The City ◽  
Vaccination Period

Of the acute respiratory viral infections in the farms of the Udmurt Republic, parainfluenza-3, respiratory syncytial infection, infectious rhinotracheitis, viral diarrhea are the most common. For the prevention of these cattle diseases, the inactivated combined vaccine Kombovak and Kombovak R. is used. Despite the widespread use of this vaccine, there is an ambiguous situation in the farms of UR and the percentage of ARVI incidence is extremely variable. Along with general economic factors, this can be explained using different schemes for the use of the vaccine. The work was carried out in the conditions of an industrial livestock complex located in the Uvinsky district of the Udmurt Republic. During the period of the work, 1,383 heads of cattle vaccinated with the Kombovak-R vaccine were monitored. Laboratory tests were carried out in the BI UR "Udmurt Veterinary Diagnostic Center" in the city of Izhevsk and LLC "Independent Veterinary Laboratory "Chance-Bio" in the city of Moscow. Determination of immunity intensity and retrospective serological diagnosis of ARVI was carried out by examining paired blood serum samples. Blood serum samples were taken from clinically healthy cows at the 6th month of pregnancy, i.e. at the end of the inter-vaccination period, as well as from unvaccinated calves with a live weight of 50-55 kg at the age of 17-18 days and after 21 days, respectively. When studying the preservation of post-vaccination immunity in cows, it was found that only two out of five studied animals have a protective level of antibodies to acute respiratory viral infections by the end of the inter-vaccination period. Serological screening of calves showed that antibodies to the pathogens of IRT, VD, RSI and PI-3 were determined in all samples. nevertheless, the titers of antibodies to ARVI pathogens differed significantly.

scholarly journals Clinical and epidemiological Semiotics in the diagnosis of etiology of acute respiratory viral infections in adults

2016 ◽  
Vol 21 (5) ◽  
pp. 268-273
Author(s):  
Aleksandr F. Popov ◽  
S. L Kolpakov ◽  
A. I Simakova ◽  
K. A Dmitrenko
Keyword(s):  
Viral Infections ◽  
Adenovirus Infection ◽  
Recent Period ◽  
Primorsky Krai ◽  
Etiological Diagnosis ◽  
Pcr Method ◽  
Respiratory Viral Infections ◽  
Syncytial Virus ◽  
Specific Symptoms ◽  
The City

For etiological diagnosis of acute respiratory viral infections the improvement of clinical semiotics and searchfor epidemiological consistent patterns are advantageous. Aim the establishment of consistent patterns of the clinical picture of etiologically AIRS decoded by PCR method and validities of epidemiological signs in the Primorsky Krai in the recent period. The material of the study were medical history cases on 276 patients admitted to the infectious department of Primorye Regional Clinical Hospital №2 in the city of Vladivostok in 2014 with a diagnosis of AIRS. Results. In the etiological structure of patients there was dominated influenza (48.2%). Hereafter there were: rhinovirus infection (13.0%), parainfluenza (11.2%), metapneumovirus infection (9,8,5%), adenovirus infection (8.0%). The minimum share was presented by bocavirus (HBoV)) infection (5.16%) and the respiratory syncytial virus, (HRSV) infection (4.7%). There were established the most sensitive and specific symptoms of considered infections. There were revealed features of the seasonality and the age structure of the patients, affecting on the efficiency of diagnosis.

Strength of post-vaccination population immunity in cattle to pathogens of acute respiratory viral infections

2021 ◽  
pp. 109-116
Author(s):  
Antonina Pavlovna Poryvaeva ◽  
Elena Vladimirovna Pechura ◽  
Alexander Sergeevich Krasnoperov ◽  
Venera Rashidovna Nurmiyeva
Keyword(s):  
Viral Infections ◽  
Post Vaccination ◽  
Population Immunity ◽  
Respiratory Viral Infections

SEROLOGICAL DIAGNOSIS OF PERTUSSIS IN OLDER PERSONS

2020 ◽  
Vol 65 (8) ◽  
pp. 492-495
Author(s):  
T. A. Skirda ◽  
O. Yu. Borisova ◽  
M. S. Petrova ◽  
A. B. Borisova ◽  
S. Yu. Kombarova
Keyword(s):  
Blood Serum ◽  
Threshold Level ◽  
Test System ◽  
Serum Samples ◽  
Pertussis Infection ◽  
Diagnostic Center ◽  
Group 2 ◽  
Definition Of ◽  
Level Group ◽  
Group 1

The aim of the work was to assess the effectiveness of serodiagnosis of pertussis in people over 50 who complained of prolonged cough. The study included 30 patients over the age of 50 who applied to the consultative diagnostic center complaining of a prolonged cough in the period from 2015 - 2020. Blood serum samples were investigated in enzyme immunoassay with the definition of antitussive antibodies of three classes - IgM, IgG, IgA in the commercial test system RIDASCREEN (R-Biopharm AG, Germany). It was found that in the serum samples of individuals over the age of 50, IgM antibodies above the threshold level were not detected. Patients were divided into two groups - with IgG and IgA antibodies above the threshold level (group 1) and below the threshold level (group 2). In the first group, in 83.3% and 61.1% of patients, the levels of antibodies of the IgG and IgA class significantly exceeded the threshold level (189.8 ± 16.7 U / ml and 290 ± 20 U / ml, respectively), which indicated a pertussis infection; in 5.6% and 38.9% of patients, IgG and IgA class antibodies slightly exceeded the threshold level (20 U / ml and 43 ± 2.3 U / ml, respectively), which indicated a dying infection. In the second group, in 100% of patients, antibodies of the IgM and IgA classes were determined below threshold levels, and IgG antibodies were detected in 58.3% of individuals at low rates, which corresponded to the natural immunological background of individuals not infected with pertussis pathogen. Therefore, in the presence of a prolonged cough in adults, it is advisable to study blood serum samples for the presence of antitussive antibodies of three classes, which is especially important when people of older age live in families with young children and pregnant women

scholarly journals Epidemiological Peculiarities of the Flu Epidemic of 2016 in St. Petersburg

2016 ◽  
Vol 15 (4) ◽  
pp. 13-21 ◽  
Author(s):  
L. S. Karpova ◽  
N. M. Popovtseva ◽  
T. P. Stolyarova ◽  
K. A. Stolyarov ◽  
O. S. Konshina ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Viral Infections ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Saint Petersburg ◽  
Population Immunity ◽  
Epidemic Period ◽  
The Russian Federation ◽  
Respiratory Viral Infections ◽  
The City

To identify the peculiarities of manifestation of epidemic process of influenza in 2016, and causes high morbidity and mortality in St. Petersburg, a comparative analysis of the incidence of influenza and acute respiratory viral infections, hospitalization and mortality in children and adults during the epidemic of 2016 in St. Petersburg and other 58 the observed cities of the Russian Federation. The epidemic of 2016 in St. Petersburg from other cities were characterized by a greater intensity: the duration of the epidemic; the incidence of the population on the peak (at 1.9 and 1.3%), within the boundaries of the epidemic in the city (7.7 and 5.4%) and the country (11.9 and 9,6%); shares admitted to hospital with a diagnosis of «influenza» among the whole population (17.1 and 14,0%); greater mortality from influenza among the whole population (3.3 tims), persons 15 - 64 (in 3 times) and 65 years and older (2.8 times). The low level of population immunity in Saint-Petersburg in the before the epidemic period and lower frequency of hospitalization of patients with influenza and ARVI among the population as a whole (2.4% and 3.6 percent), particularly children and persons over 65 years of age (2 times), could be the cause of high morbidity and mortality from influenza in St. Petersburg.

scholarly journals Significance of complex laboratory diagnostics of ARVI for veterinary practice

2020 ◽  
Vol 196 (5) ◽  
pp. 59-67
Author(s):  
A. PORYVAEVA ◽  
O Petrova ◽  
Elena Pechura ◽  
Natalia Bezborodova ◽  
Ya. LYSOVA
Keyword(s):  
Respiratory Diseases ◽  
Viral Infections ◽  
Respiratory Infections ◽  
Federal District ◽  
Laboratory Diagnostics ◽  
Agricultural Enterprises ◽  
Udmurt Republic ◽  
Acute Respiratory Diseases ◽  
Respiratory Viral Infections ◽  
Diagnostic Technologies

Abstract. This article summarizes the results of laboratory studies of acute respiratory viral infections of cattle in agricultural enterprises of the Ural Federal district and the Udmurt Republic. The purpose of the research was to show the spread of respiratory viral infections in cattle in various regions and the significance of laboratory diagnostics in this pathology. According to research data 815 samples for the period 2018–2020 a variety of combinations of mixed respiratory viruses in animals was detected using biomaterials from different age patients and patients with respiratory diseases of cattle from agricultural enterprises of the Ural Federal district, the Volga Federal District and the Udmurt Republic using polymerase chain reaction, indirect hemagglutination reaction, hemagglutination inhibition reaction, Elisa , and enzyme immunoassay. Scientific novelty. The etiological structure of mixed acute respiratory viral infections in cattle in agricultural enterprises in four regions of the Ural Federal District, the Volga Federal District and the Udmurt Republic in 2018–2020 was studied using modern diagnostic technologies. Results. In the Ural Federal District, the Volga Federal district and the Udmurt Republic, 80 % of cases of acute respiratory diseases were caused by bovine viral infections, mainly representatives of 2 families of viruses whose genome is represented by an RNA molecule (paramixoviruses, togaviruses) and a family of viruses whose genome is represented by a DNA molecule (herpesviruses,). The leading place among acute respiratory infections was occupied by infectious rhinotracheitis of cattle.

scholarly journals Colostral immunity as an analytical factor in predicting the development of acute respiratory viral infections in calves

2021 ◽  
Vol 1 (1) ◽  
pp. 29-32
Author(s):  
E. N. Shilova ◽  
A. P. Poryvaeva ◽  
E. V. Pechura ◽  
L. V. Khalturina
Keyword(s):  
Respiratory Syncytial Virus ◽  
Viral Infections ◽  
Bovine Respiratory Syncytial Virus ◽  
Passive Immunity ◽  
Infectious Bovine Rhinotracheitis ◽  
Post Vaccination ◽  
Diarrhea Virus ◽  
Respiratory Viral Infections ◽  
Syncytial Virus ◽  
Infectious Bovine Rhinotracheitis Virus

To reduce the incidence of acute respiratory viral infections in cattle, routine vaccination of mother cows is carried out. There is a direct dependence of the passive immunity level in calves on the vaccination efficacy in cows. The paper presents the results of a study of colostral immunity in calves and post-vaccination immunity in cows against the agents of acute respiratory viral infections in agricultural facilities located on the territory of the Ural and Volga Federal Districts. In the farms under study (n = 10), cattle are vaccinated with inactivated vaccines: “COMBOVAC” and “COMBOVAC-R” (OOO Vetbiokhim, Russia), “HIPRABOVIS® 4” (Laboratorios Hipra, S. A., Spain). The study of postvaccinal immunity level in cows showed that the levels of antibodies to infectious bovine rhinotracheitis virus (5.3–8.0 log2), bovine viral diarrhea virus (3.5–4.8 log2), bovine parainfluenza-3 virus (6.8–8.5 log2) and bovine respiratory syncytial virus (4.2-4.5 log2) in cattle confer protection. When evaluating the results of serological diagnostics of passive immunity in calves to acute respiratory viral infections, it was found that the level of colostral antibodies in them is lower than the level of post-vaccination antibodies in cows: to infectious bovine rhinotracheitis virus by 34.2–58.8%; to bovine diarrhea virus by 37.5–45.0%; to bovine parainfluenza-3 virus by 14.7–35.4 and to bovine respiratory syncytial virus by 23.5-42.2%. To ensure epizootic favourable situation, it is proposed to adjust the schedules of vaccination against bovine diseases in herds, infected by acute respiratory viral infections for dairy farms under study.

scholarly journals CLINICAL AND ETIOLOGICAL CHARACTERISTICS OF ACUTE RESPIRATORY VIRAL INFECTIONS IN HOSPITALIZED CHILDREN OF THE CITY OF KHABAROVSK IN EPIDEMIC SEASONS 2014—2017

2018 ◽  
Vol 17 (2) ◽  
pp. 6-14 ◽  
Author(s):  
R. A. Gladkikh ◽  
V. P. Molochny ◽  
L. V. Butakova ◽  
O. E. Trotsenko ◽  
V. I. Reznik ◽  
...  
Keyword(s):  
Viral Infections ◽  
Hospitalized Children ◽  
Respiratory Viral Infections ◽  
The City

scholarly journals Investigations of prevalence of antibodies to B.canis in stray dogs in territory of Belgrade

2006 ◽  
Vol 60 (1-2) ◽  
pp. 43-49
Author(s):  
Sonja Radojicic ◽  
Milica Cilerdzic ◽  
Bane Dimic ◽  
Jasmina Kircanski
Keyword(s):  
Blood Serum ◽  
Diagnostic Procedure ◽  
Test Tube ◽  
Serum Samples ◽  
Stray Dogs ◽  
Bacteriological Finding ◽  
Brucella Canis ◽  
The City

The paper covers investigations of stray dogs in the territory of the city of Belgrade. A total of 184 blood serum samples were examined for the presence of antibodies specific to Brucella canis. The method of slow agglutination in a test tube with 2- mercaptoethanol was used in the diagnostic procedure. Of the 184 examined serums, 49 (26.63%) had a titer of 1/50, 25 serums had a titer of 1/100 (13.58%), while 20 serums had a titer equal to or bigger than 1/200 (10.87%). Furthermore, 15 samples of full blood from serologiclly negative animals were also presented for isolation. The bacteriological finding for these samples was negative. The obtained results indicate that the number of seropositive stray dogs in the territory of Belgrade is extremely high and that 10.87% of the testes animals are definitely infected with Brucella canis.

Functional state of the liver in different clinical forms of respiratory viral and viral bacterial infections in children of early age

1993 ◽  
Vol 74 (3) ◽  
pp. 211-214
Author(s):  
H. S. Khaertynov
Keyword(s):  
Blood Serum ◽  
Functional State ◽  
Bacterial Infections ◽  
Viral Infections ◽  
Clinical Manifestations ◽  
Early Age ◽  
Acute Period ◽  
Clinical Forms ◽  
Respiratory Viral Infections ◽  
Sick Children

The content of prealbumin, fibroncctine and urokanisasc activity are determined in 232 sick children of early age with different clinical manifestations of acute respiratory viral infections (uncomplicated forms and acute respiratory viral infections ' complicated by pneumonia). It is stated that the acute period of acute respiratory viral infections goes in the presence of a decrease the levels of prealbumin, fibronectine and an increase of urokanisase activity of blood serum. The connection between pronounced changes of the parameters studied and manifestations of the intoxication symptoms is revealed. More pronounced changes are noted in grave forms of the disease (toxicosis development) and in presence of bacterial complications (pneumonia).

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