scholarly journals Epidemiological Peculiarities of the Flu Epidemic of 2016 in St. Petersburg

2016 ◽  
Vol 15 (4) ◽  
pp. 13-21 ◽  
Author(s):  
L. S. Karpova ◽  
N. M. Popovtseva ◽  
T. P. Stolyarova ◽  
K. A. Stolyarov ◽  
O. S. Konshina ◽  
...  

To identify the peculiarities of manifestation of epidemic process of influenza in 2016, and causes high morbidity and mortality in St. Petersburg, a comparative analysis of the incidence of influenza and acute respiratory viral infections, hospitalization and mortality in children and adults during the epidemic of 2016 in St. Petersburg and other 58 the observed cities of the Russian Federation. The epidemic of 2016 in St. Petersburg from other cities were characterized by a greater intensity: the duration of the epidemic; the incidence of the population on the peak (at 1.9 and 1.3%), within the boundaries of the epidemic in the city (7.7 and 5.4%) and the country (11.9 and 9,6%); shares admitted to hospital with a diagnosis of «influenza» among the whole population (17.1 and 14,0%); greater mortality from influenza among the whole population (3.3 tims), persons 15 - 64 (in 3 times) and 65 years and older (2.8 times). The low level of population immunity in Saint-Petersburg in the before the epidemic period and lower frequency of hospitalization of patients with influenza and ARVI among the population as a whole (2.4% and 3.6 percent), particularly children and persons over 65 years of age (2 times), could be the cause of high morbidity and mortality from influenza in St. Petersburg.

2021 ◽  
Vol 15 ◽  
pp. 175346662199505
Author(s):  
Alastair Watson ◽  
Tom M. A. Wilkinson

With the global over 60-year-old population predicted to more than double over the next 35 years, caring for this aging population has become a major global healthcare challenge. In 2016 there were over 1 million deaths in >70 year olds due to lower respiratory tract infections; 13–31% of these have been reported to be caused by viruses. Since then, there has been a global COVID-19 pandemic, which has caused over 2.3 million deaths so far; increased age has been shown to be the biggest risk factor for morbidity and mortality. Thus, the burden of respiratory viral infections in the elderly is becoming an increasing unmet clinical need. Particular challenges are faced due to the interplay of a variety of factors including complex multimorbidities, decreased physiological reserve and an aging immune system. Moreover, their atypical presentation of symptoms may lead to delayed necessary care, prescription of additional drugs and prolonged hospital stay. This leads to morbidity and mortality and further nosocomial spread. Clinicians currently have limited access to sensitive detection methods. Furthermore, a lack of effective antiviral treatments means there is little incentive to diagnose and record specific non-COVID-19 viral infections. To meet this unmet clinical need, it is first essential to fully understand the burden of respiratory viruses in the elderly. Doing this through prospective screening research studies for all respiratory viruses will help guide preventative policies and clinical trials for emerging therapeutics. The implementation of multiplex point-of-care diagnostics as a mainstay in all healthcare settings will be essential to understand the burden of respiratory viruses, diagnose patients and monitor outbreaks. The further development of novel targeted vaccinations as well as anti-viral therapeutics and new ways to augment the aging immune system is now also essential. The reviews of this paper are available via the supplemental material section.


2016 ◽  
Vol 21 (5) ◽  
pp. 268-273
Author(s):  
Aleksandr F. Popov ◽  
S. L Kolpakov ◽  
A. I Simakova ◽  
K. A Dmitrenko

For etiological diagnosis of acute respiratory viral infections the improvement of clinical semiotics and searchfor epidemiological consistent patterns are advantageous. Aim the establishment of consistent patterns of the clinical picture of etiologically AIRS decoded by PCR method and validities of epidemiological signs in the Primorsky Krai in the recent period. The material of the study were medical history cases on 276 patients admitted to the infectious department of Primorye Regional Clinical Hospital №2 in the city of Vladivostok in 2014 with a diagnosis of AIRS. Results. In the etiological structure of patients there was dominated influenza (48.2%). Hereafter there were: rhinovirus infection (13.0%), parainfluenza (11.2%), metapneumovirus infection (9,8,5%), adenovirus infection (8.0%). The minimum share was presented by bocavirus (HBoV)) infection (5.16%) and the respiratory syncytial virus, (HRSV) infection (4.7%). There were established the most sensitive and specific symptoms of considered infections. There were revealed features of the seasonality and the age structure of the patients, affecting on the efficiency of diagnosis.


Author(s):  
A. Gluhova

The typology of public buildings is constantly developing, and identifying rational ways to evolve concert halls is considered an urgent task. The development of new types of concert halls requires a comprehensive consideration of factors, both General and regional, that affect the requirements for concert institutions and the concert system as a whole. In the Russian Federation, there is an active process of opening new concert venues, but the development process is chaotic, without taking into account the conditions of specific cities – social, demographic, and economic. Their quality and principles of placement do not match the needs of visitors. Thus, the need to analyze the factors identified in the course of studying the experience of designing concert halls is revealed. The basic factors affect the typology of concert halls in general, they must be taken into account for the development of the typology of concert halls. The article also discusses regional factors using the example of the city of St. Petersburg. The specific features, relationships and the nature of the impact of factors in the architectural aspect are revealed. The article notes the inequality of factors in terms of the degree of their influence on the formation of the architectural typology of concert halls. The most significant factors include: cultural, urban planning, socio-demographic, economic, functional and planning factors.


2021 ◽  
Vol 36 ◽  
pp. 06047
Author(s):  
E.V. Maksimova ◽  
E.S. Klimova ◽  
E.A. Merzlyakova ◽  
L.L. Maksimov

Of the acute respiratory viral infections in the farms of the Udmurt Republic, parainfluenza-3, respiratory syncytial infection, infectious rhinotracheitis, viral diarrhea are the most common. For the prevention of these cattle diseases, the inactivated combined vaccine Kombovak and Kombovak R. is used. Despite the widespread use of this vaccine, there is an ambiguous situation in the farms of UR and the percentage of ARVI incidence is extremely variable. Along with general economic factors, this can be explained using different schemes for the use of the vaccine. The work was carried out in the conditions of an industrial livestock complex located in the Uvinsky district of the Udmurt Republic. During the period of the work, 1,383 heads of cattle vaccinated with the Kombovak-R vaccine were monitored. Laboratory tests were carried out in the BI UR "Udmurt Veterinary Diagnostic Center" in the city of Izhevsk and LLC "Independent Veterinary Laboratory "Chance-Bio" in the city of Moscow. Determination of immunity intensity and retrospective serological diagnosis of ARVI was carried out by examining paired blood serum samples. Blood serum samples were taken from clinically healthy cows at the 6th month of pregnancy, i.e. at the end of the inter-vaccination period, as well as from unvaccinated calves with a live weight of 50-55 kg at the age of 17-18 days and after 21 days, respectively. When studying the preservation of post-vaccination immunity in cows, it was found that only two out of five studied animals have a protective level of antibodies to acute respiratory viral infections by the end of the inter-vaccination period. Serological screening of calves showed that antibodies to the pathogens of IRT, VD, RSI and PI-3 were determined in all samples. nevertheless, the titers of antibodies to ARVI pathogens differed significantly.


Author(s):  
Antonina Pavlovna Poryvaeva ◽  
Elena Vladimirovna Pechura ◽  
Alexander Sergeevich Krasnoperov ◽  
Venera Rashidovna Nurmiyeva

2019 ◽  
Vol 11 (1) ◽  
pp. 71-75
Author(s):  
S. M. Bezrodnova ◽  
N. A. Yatsenko ◽  
O. O. Kravchenko ◽  
Sh. M. Khurtsilava

Objective: to study the clinical and epidemiological features of influenza in children in the Stavropol Territory.Materials and methods: influenza prevalence is analyzed from 2015 to 2017 the paper used the data from the Territorial Rospotrebnadzor in the Stavropol Territory. We used the following methods: bibliographic, monographic description, epidemiological, analytical, statistical methods.Results: Among the deciphered acute respiratory viral infections, the specific gravity of influenza A (H1N1) 09 in 2016 reached 78%, and in 2017 influenza B prevailed – in 57,4% of children, and influenza A (H3N2) – in 42,6% of cases. In 2016 68,5% of children under 6 years of age, of all admitted, were hospitalized, and in 2017 – 83,86%. We presented the peculiarities of the course of influenza in different epidemic seasons.Conclusion: Unvaccinated children up to 6 years of age have the disease mainly in severe forms and with complications. The epidemic period began to increase in 2015–2016 at week 52, and in 2016–2017 from week 48, ended at week 13 and at week 17. At the epidemic of 2015–2016, intoxication syndrome with chills, microcirculation disturbance, catarrhal syndrome, ARDS prevailed in the clinical picture. The epidemic season of 2016–2017 was characterized by intoxication syndrome, encephalic reaction, hemorrhagic and myalgic syndromes.


Author(s):  
V. P. Kosolapov ◽  
M. V. Yarmonova

Introduction. The article is devoted to the analysis of the state of cardiovascular morbidity (CVD), mortality of the population and the demographic situation, as well as determining the prevalence of CVD as a medical and social problem at the federal and regional levels. The analysis of the implementation of the policy of providing medical care to patients with CVD, modern scientific publications on the indicated problem, and the search for ways to solve the medical and social problem of high morbidity and mortality from CVD are carried out.Materials and methods. The data of official statistical information on the morbidity and mortality of the adult population of the Russian Federation and the Voronezh region for 2010–2019 were used, the works of modern domestic and foreign scientists dealing with the solution of this problem were studied.Results. It has been established that high CVD and mortality are an acute medical and social problem. Mortality from CVD in Russia in 2019 amount to 46.8% of the total number of deaths. The mortality rate from CVD in Russia exceeds that in the developed countries of the European Union. Despite the presence of positive trends in the fight against this disease, the mortality rate from CVD in the Voronezh region is higher than the average for the Russian Federation (601.8 and 573.2 per 100 thousand population, respectively). The deterioration of the demographic situation, the presence of active targeted projects in this area are the basis for conducting scientific research to find ways to duce CVD and mortality in the adult population.Conclusion. The high morbidity and mortality from CVD requires a search for new ways to solve the problem, since the existing approaches to its solution are not holistic and universal. It is urgent to develop an integrated approach that takes into account the medical and social characteristics of the adult population of the region.


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