scholarly journals How Protein Labeling Applying

2021 ◽  
Vol 290 ◽  
pp. 01020
Author(s):  
Bian Xinyu ◽  
Fan Sun ◽  
Zhixuan Xu

In recent years, biosensing has played an irreplaceable position in scientific fields as well as our daily lives. A biosensor is an instrument that is sensitive to biological substances and converts its concentration into electrical signals for detection. It is an analysis tool or system composed of immobilized biologically sensitive materials as identification elements, appropriate physical and chemical transducers and signal amplification devices, and it has the functions of both a receiver and a converter. Pregnancy test sticks, blood glucose testing, etc. in life are all potential biosensors. The main point of this paper is to introduce several main techniques of biosensing for better understanding, like ELISA, fusion proteins, fluorescent probe and others. In the future, the bright future for them is also worth looking forward to if more researches and experiments can be processed in this area, for example, in the detection and treatment of cancer, medical technology can be further improved.

2021 ◽  
pp. 084456212110206
Author(s):  
Mezgebu Gode ◽  
Fekadu Aga ◽  
Aklil Hailu

Background Type 2 diabetes mellitus (T2D) has become a global health challenge. Diabetic peripheral neuropathy (DPN) is one of the common comorbidities of T2D that may affect the ability to perform diabetes self-care. Purpose To compare self-care practices between adult T2D patients with and without comorbid DPN and identify factors predicting self-care practices. Methods In this cross-sectional study, conducted at tertiary hospitals in Ethiopia, a total of 216 (108 with DNP and 108 without DNP) participants completed an interviewer-administered questionnaire including measures of diabetes self-care practices, self-evaluated peripheral neuropathy, self-efficacy, diabetes knowledge, and social support. Results Adult T2D patients with comorbid DPN had lower dietary (P< 0.001), exercise (P< 0.001), blood glucose testing (P = 0.001), and foot (P = 0.007) self-care practice than those without DPN. Social support is a significant predictor of dietary self-care in both groups while predicting foot self-care and blood glucose testing in those with comorbid DPN. Moreover, occupation, education, and having a glucometer are significant predictors of diabetes self-care practice in both groups. Conclusion This study found that adult T2D patients with comorbid DPN have poorer diabetes self-care practice than those without comorbid DPN. Interventions should focus on addressing social support and access to a glucometer in order to improve diabetes self-care practices in adult T2D patients with comorbid DPN.


2017 ◽  
Vol 25 (5) ◽  
pp. 652-664
Author(s):  
Danielle Arigo ◽  
Vanessa Juth ◽  
Paula Trief ◽  
Kenneth Wallston ◽  
Jan Ulbrecht ◽  
...  

This study examined reported post-traumatic stress disorder symptoms in adults with poorly controlled type 2 diabetes who had no history of psychiatric diagnosis or treatment ( n = 184, MHbA1c = 9.13%, standard deviation = 1.68). Participants reported moderate to severe intensity of post-traumatic stress disorder symptoms ( M = 19.17, SD = 17.58). Together, depressive and post-traumatic stress disorder symptoms accounted for 10–40 percent of the variance in type 2 diabetes outcomes; post-traumatic stress disorder symptoms were associated with elevated diabetes distress and more frequent exercise and self-blood glucose testing (unique R2 ~ 3%). Post-traumatic stress disorder symptoms may be overlooked in type 2 diabetes among patients without formal psychiatric diagnoses, and warrant increased attention.


2021 ◽  
Vol 9 (1) ◽  
pp. 62-72
Author(s):  
Allison DaSantos ◽  
◽  
Carlisle Goddard ◽  
Dalip Ragoobirsingh ◽  
◽  
...  

<abstract><sec> <title>Purpose</title> <p>Diabetes management requires adherence to complicated self-care behaviors. Therefore, the emotional state of the individual living with diabetes, is likely to affect their ability to comply with recommendations. This study explored the relationship of self-care adherence to diabetes distress and depression in Barbadian adults with type 2 diabetes.</p> </sec><sec> <title>Methods</title> <p>Adults aged 20 to 80 years, with type 2 diabetes, completed self-report questionnaires comprised of a profile section consisting of demographic and clinical characteristics; and standardized questionnaires comprising, The Diabetes Distress Scale (DDS), The Patient Health Questionnaire (PQH-9), and the Summary of Diabetes Self-care Activities Scale (SDSCA). Additionally biological measures (BP and HbA1c) were collected.</p> </sec><sec> <title>Results</title> <p>For the 509 participants there were no differences in adherence for males (30.8%) and females (69.2%), high diabetes distress and depression were associated with low adherence. General diet was negatively associated with BP and HbA1c; while HbA1c was positively correlated with blood glucose testing.</p> </sec><sec> <title>Conclusion</title> <p>Self-care non-adherence is more than a behavioral problem; it is a multidimensional phenomenon inclusive of demographic factors, condition or disease factors, psychological and social factors.</p> </sec></abstract>


2000 ◽  
Vol 2 (2) ◽  
pp. 221-229 ◽  
Author(s):  
Ben Feldman ◽  
Geoff McGarraugh ◽  
Adam Heller ◽  
Nancy Bohannon ◽  
Jay Skyler ◽  
...  

2003 ◽  
Vol 5 (6) ◽  
pp. 983-989 ◽  
Author(s):  
D. Fedele ◽  
A. Corsi ◽  
C. Noacco ◽  
F. Prisco ◽  
S. Squatrito ◽  
...  

2021 ◽  
pp. 1-9
Author(s):  
Haifen Zhang ◽  
Shuhui Lailan ◽  
Shiyu Zhao ◽  
Qian Liu ◽  
Nina Fang ◽  
...  

BACKGROUND: Portable blood glucose meters are the main method for detecting the blood glucose status of clinical patients. OBJECTIVE: To investigate the accuracy of detecting blood glucose in haemodialysis patients by sampling two blood glucose meters through the haemodialysis line. METHODS: Convenient sampling was used to select 80 patients with maintenance haemodialysis. The patients were sampled through the arterial end of the haemodialysis line within three minutes of being put on the machine. One specimen was tested by glycemeter1, which can identify the type of blood in the arteries and veins, and glycemeter2, which can only detect blood glucose in the capillaries for bedside blood glucose testing. The other specimen was sent to the laboratory biochemical analyser for blood glucose testing. RESULTS: When the blood glucose value of the first blood glucose meter (No. 1) was compared with the laboratory biochemical analyser, the correlation coefficient was r = 0.805 (p < 0.05), the out of value of the first blood glucose meter accounted for 4.4%, and the consistency reached 95% (p < 0.05). When the blood glucose value of the second blood glucose meter (No. 2) was compared with the laboratory biochemical analyser, the correlation coefficient was r = 0.800 (p < 0.05), the out of value of the second blood glucose meter accounted for 4.4%, and the consistency reached 95% (p < 0.05). CONCLUSIONS: For patients with maintenance haemodialysis, the blood glucose values detected by the two bedside blood glucose meters using arteriovenous mixed blood in the pipeline do not affect the accuracy and can respond more realistically.


2016 ◽  
Vol 33 (9) ◽  
pp. 313-315a ◽  
Author(s):  
Steve Chaplin

Diabetes Care ◽  
1981 ◽  
Vol 4 (3) ◽  
pp. 417-419 ◽  
Author(s):  
P. Kubilis ◽  
A. L. Rosenbloom ◽  
D. Lezotte ◽  
J. H. Silverstein ◽  
P. Cimino ◽  
...  

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