Thiobarbituric acid reactive substances and vitamin E in healthy women and patients with pregnancy-induced hypertension

2001 ◽  
Vol 1 (5) ◽  
pp. 259-266
Author(s):  
N[eacute]stor J. Aparicio ◽  
Mirta Joao ◽  
Pablo Fernandez ◽  
Marta Cortelezzi ◽  
Viviana Caram[eacute]s ◽  
...  
2020 ◽  
Vol 50 (1) ◽  
Author(s):  
Thiago Luís Magnani Grassi ◽  
Juliana Sedlacek-Bassani ◽  
Elisa Helena Giglio Ponsano

ABSTRACT: The aim of this study was to evaluate the effect of the inclusion of microbial biomass on the oxidative rancidity of tilapia rations stored for 12 months. Treatments included a control diet and diets supplemented with either 0.01% vitamin E, 0.25 and 0.5% of Saccharomyces cerevisiae and 0.25 and 0.5% of Spirulina platensis. Experimental diets were stored in the dark inside plastic bags at room temperature (25 °C) for 12 months. The oxidative rancidity was measured as thiobarbituric acid reactive substances (TBARS). It was concluded that the inclusions of Spirulina platensis at 0.25% (1.734 ± 0.206) and 0.5% (1.629 ± 0.181) and Saccharomyces cerevisiae at 0.5% (1.459 ± 0.305) minimized the oxidative rancidity in comparation to control diet (2.843 ± 0.109) of Nile tilapia until 12 months of storage.


2021 ◽  
Vol 10 (4) ◽  
pp. 246-251
Author(s):  
Kausar Aamir ◽  
Arfa Azhar ◽  
Fatima Abid ◽  
Shamaila Khalid ◽  
Fiza Ali Khan

Background: Preeclampsia is a multifactorial disorder comprising many organs. Oxidative stress (OS) has been intensely linked to its occurrence. Vitamin E, a lipophilic chain breaking antioxidant has been proved to suppress the OS. Present study was designed to investigate antioxidant nutrient profile in patients with different grades of pregnancy induced hypertension (PIH) and to compare them with normal pregnant controls. Methods: The study group comprised 110 patients divided in three groups as Group A (n=40) Normotensive patients, Group B (n=40) Mild hypertensive, Group C (n=30) Severe hypertensive. Vitamin A, B-Carotene, serum alpha tocopherol (vitamin E) and vitamin C levels were analysed. Results: Serum alpha tocopherol (vitamin E) was significantly low in severe and mild cases (0.32±0.00 mg/dl, 0.74±0.03 mg/dl respectively), when compared with normal pregnant women levels (0.78±0.040). All other nutrients were also found to be in reduced quantity for Group C when compared to control group (P value <0.001). Conclusion: It was therefore concluded that in patients with risk of preeclampsia (PE) adequate antioxidant nutrients may have a role in cessation of free radical-mediated cell disturbances, and thereby protecting against endothelial cell damage, which is the key factor in PE development.


2012 ◽  
Vol 81 (3) ◽  
pp. 275-280 ◽  
Author(s):  
Renata Stavinohová ◽  
Jana Lorenzová ◽  
Ivana Papežíková ◽  
Ivana Borkovcová ◽  
Jakub Pfeifr ◽  
...  

The present study determined markers of oxidative and antioxidative activity in dog females affected with mammary gland tumour compared to healthy ones. The effect of additional vitamin E supplementation on oxidative and antioxidative status was evaluated as well. The study included 29 female dogs divided into 4 groups (groups 1 and 2 included females with a mammary gland tumour; groups 3 and 4 included healthy female dogs). Additional vitamin supplement containing α-tocopherol was given to the females of groups 1 and 4. Dogs from groups 1 and 2 were anaesthetized before surgery (ovariohysterectomy and mastectomy); anaesthesia was used also in group 3, but without performeing surgery. The content of vitamin E (free α-tocopherol), marker of antioxidative status, was measured in blood serum by liquid chromatography. The concentration of thiobarbituric acid reactive substances, marker of oxidative status, in serum and concentrations of protein and non-protein thiol groups, markers of oxidative and antioxidative status, in blood serum and in red blood cells were measured colorimetrically. In females with a mammary gland tumour from group 2, concentration of thiobarbituric acid reactive substances was significantly higher than 14 days after surgery and compared to healthy ones as well. In females with a mammary gland tumour from group 2, concentration of protein thiol groups in serum was significantly lower and concentration of non-protein thiol groups in serum was significantly higher than in healthy controls. The values of protein thiols in erythrocytes in females with mammary gland tumour from group 1 were significantly higher before supplementation with vitamin E. The present study revealed that females with a mammary gland tumour were more burdened with oxidative stress compared to healthy dogs. The removal of the mammary gland tumour led to improvement of oxidative and antioxidative status. This is the first report focusing on the effect of additional α-tocopherol supplementation on reducing oxidative stress by increasing antioxidative activity in females affected with mammary gland tumour; however, we did not prove it.


2010 ◽  
Vol 90 (3) ◽  
pp. 371-378 ◽  
Author(s):  
A. Schiavone ◽  
M. Marzoni ◽  
A. Castillo ◽  
J. Nery ◽  
I. Romboli

A trial was conducted in order to assess the fatty acid composition and lipid stability of breast meat from Muscovy ducks (Cairina moschata domestica L.) fed a basal diet supplemented with 20 g kg-1 of soybean oil or fish oil and 30 or 230 mg kg-1 α-tocopheryl acetate (α-TA). A total of 120 one-day-old female muscovy ducklings were distributed over 12 pens (10 birds/pen). Growth performance traits were measured through the study. Each dietary treatment was randomly administered to three replicates when birds were 43 d until the slaughtering age of 66 d. Dietary treatments did not induce differences in growth performances and slaughter traits. Similarly, proximate composition and pH of breast muscle were not influenced by the diets. Significant increases in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) contents in breast meat of ducks fed fish-oil-supplemented diets was observed. Lipid oxidation, expressed as thiobarbituric acid reactive substances (TBARS), of breast meat from birds fed 230 mg kg-1 α-TA-supplemented diets was significantly lower, compared with those fed diets supplemented with 30 mg kg-1 α-TA, both 1 and 7 d after slaughter.Key words: Duck, meat, fatty acid, vitamin E, thiobarbituric acid reactive substances


2019 ◽  
Vol 09 (03) ◽  
pp. 170-174
Author(s):  
Kausar Aamir ◽  
Fatima Abid ◽  
Arfa Azhar

Objective: To correlate the preventive role of vitamin E levels and platelet count in patients with different grades of pregnancy induced hypertension. The secondary objective was to compare these grades with normal pregnant patients. Study Design and Setting: This study was conducted in Obstetric OPD of Jinnah Postgraduate Medical Centre (JPMC), Karachi, from April 2002 through April 2004. Methodology: The study group included 110 patients divided in three groups as Group A: n=40 Normotensive patients, Group B: n=40 Mild hypertensive (test group I), Group C: n=30 Severe hypertensive (test group II). All women were advised not to take any multivitamin supplements. Result: Serum alpha tocopherol (vitamin E) was significantly low in severe and mild cases (0.32±0.00 mg/dl, 0.74±0.03 mg/dl respectively), when compared with normal pregnant women levels (0.78±0.040). The decreased platelet count (246820±1493.51) in mild cases and (135460±387.2) in severe cases was significant (P<0.01) as compared to the normal pregnant women (348000±574.35). The decrease platelet count values for severe cases were again significant (P<0.01) when compared with mild cases of PIH. Conclusion: In patients with risk of preeclampsia adequate antioxidant nutrients may have a role in cessation of free radicalmediated cell disturbances, and thereby protecting against endothelial cell damage, which is the key factor in preeclampsia development


2021 ◽  
Vol 9 (09) ◽  
pp. 822-826
Author(s):  
N. Imtiyazi ◽  
Furquan Ameen

The hypertension that is caused directly by gravid state is known as Pregnancy Induced Hypertension (PIH). It has an association with increased maternal morbidity and mortality. In classical Unani literature, hypertension is referred as Hejan of blood. Ibn-e-Sina (Avicenna) wrote in his book Al-Qanoon Fit Tib (Alcanon) that few times pregnant women may complain Warm-e-Qadam (Pedal Oedema). During labour, Tashannuj wa Tamaddud (Convulsions) may occur. Ilaj-bil-Ghiza (Dietotherapy) is a method of Unani treatment in which a specific diet is given for a specific disease. Dietary supplement of 400 IU Vitamin E and 1000 mg Vitamin C per day as antioxidant resulted in reducing oxidative stress, decreased endothelial activation and reduction in the risk of PIH by 61%. Specific diets mentioned in Unani medicine which contains Vitamin E and Vitamin C can be beneficial in PIH.


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