Gestational diabetes: Linking epidemiology, excessive gestational weight gain, adverse pregnancy outcomes, and future metabolic syndrome

2015 ◽  
Vol 39 (4) ◽  
pp. 254-258 ◽  
Author(s):  
Celeste Durnwald
Keyword(s):  
Metabolic Syndrome ◽  
Weight Gain ◽  
Gestational Diabetes ◽  
Gestational Weight Gain ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain ◽  
Adverse Pregnancy

scholarly journals The Impact of Gestational Weight Gain on the Risks of Adverse Maternal and Infant Outcomes among Normal BMI Women with High Triglyceride Levels during Early Pregnancy

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3454
Author(s):  
Xia-Fei Jiang ◽  
Hui Wang ◽  
Dan-Dan Wu ◽  
Jian-Lin Zhang ◽  
Ling Gao ◽  
...  
Keyword(s):  
Weight Gain ◽  
Preterm Birth ◽  
Gestational Diabetes ◽  
Early Pregnancy ◽  
Pregnancy Outcomes ◽  
Gestational Hypertension ◽  
Adverse Pregnancy Outcomes ◽  
Gestational Weight ◽  
Adverse Pregnancy ◽  
The Impact

A high maternal triglyceride (mTG) level during early pregnancy is linked to adverse pregnancy outcomes, but the use of specific interventions has been met with limited success. A retrospective cohort study was designed to investigate the impact of gestational weight gain (GWG) on the relationship between high levels of mTG and adverse pregnancy outcomes in normal early pregnancy body mass index (BMI) women. The patients included 39,665 women with normal BMI who had a singleton pregnancy and underwent serum lipids screening during early pregnancy. The main outcomes were adverse pregnancy outcomes, including gestational hypertension, preeclampsia, gestational diabetes, cesarean delivery, preterm birth, and large or small size for gestational age (LGA or SGA) at birth. As a result, the high mTG (≥2.05mM) group had increased risks for gestational hypertension ((Adjusted odds ratio (AOR), 1.80; 95% CI, 1.46 to 2.24)), preeclampsia (1.70; 1.38 to 2.11), gestational diabetes (2.50; 2.26 to 2.76), cesarean delivery (1.22; 1.13 to 1.32), preterm birth (1.42, 1.21 to 1.66), and LGA (1.49, 1.33 to 1.68) compared to the low mTG group, after adjustment for potential confounding factors. Additionally, the risks of any adverse outcome were higher in each GWG subgroup among women with high mTG than those in the low mTG group. High mTG augmented risks of gestational hypertension, preeclampsia, preterm birth, and LGA among women with 50th or greater percentile of GWG. Interestingly, among women who gained less than the 50th percentile of GWG subgroups, there was no relationship between high mTG level and risks for those pregnancy outcomes when compared to low mTG women. Therefore, weight control and staying below 50th centile of the suggested GWG according to gestational age can diminish the increased risks of adverse pregnancy outcomes caused by high mTG during early pregnancy.

scholarly journals EFFECT OF EXCESSIVE GESTATIONAL WEIGHT GAIN ON PREGNANCY OUTCOME: A CASE STUDY OF TERTIARY HOSPITALS IN BENUE STATE, NIGERIA

2020 ◽  
Vol 8 (3) ◽  
pp. 180-189
Author(s):  
Amarachi Nwaogwugwu ◽  
Nwabueze Achunam Simeon ◽  
Celestine E Ekwuluo
Keyword(s):  
Weight Gain ◽  
Pregnancy Outcome ◽  
Gestational Weight Gain ◽  
Pregnancy Outcomes ◽  
Strong Association ◽  
Adverse Pregnancy Outcomes ◽  
Value Analysis ◽  
Gestational Weight ◽  
Tertiary Hospitals ◽  
Adverse Pregnancy

Motivation/Background: Little is known of adverse pregnancy outcomes resulting from Excess Gestational Weight Gain (EGWG) in Benue state, Nigeria. In this study, we aimed to assess the effects and association of EGWG on pregnancy outcome in tertiary hospitals in Benue State. Method: We used retrospective cohort study to examine the data obtained from the general Antenatal Care (ANC) Register of 350 pregnant women who attended ANC clinic between January 1, 2016 and December 31, 2016. Pre-pregnancy Body Mass Index (BMI) was calculated by dividing weight in kilograms within first 14 weeks of gestation by square of height in meters while total gestational weight was calculated as difference between weight before, or at 14 weeks and weight at 37 weeks of gestation prior to delivery. Results: Data analysis was done using SPSS version 21. Out of the sampled folders, 103 (29.4%) women gained excess weight during pregnancy, 130 (37.1%) women gained the recommended weight while 117 (33.4%) women gained weight less than the recommended value. Analysis showed strong association between EGWG and pregnancy induced hypertension/pre-eclampsia, caesarean section and macrosomia. Conclusions: The study concluded that EGWG should be avoided by educating women on the need to gain appropriate weight during pregnancy to prevent adverse pregnancy outcomes which affect both mothers and their offspring.

scholarly journals Gestational Weight Gain—Re-Examining the Current Paradigm

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2314
Author(s):  
Jennie Louise ◽  
Andrea R. Deussen ◽  
Jodie M. Dodd
Keyword(s):  
Physical Activity ◽  
Weight Gain ◽  
Gestational Weight Gain ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Adverse Outcomes ◽  
Obese Women ◽  
Gestational Weight ◽  
Diet And Physical Activity ◽  
Adverse Pregnancy

Our aim was to investigate the underlying assumptions of the current gestational weight gain (GWG) paradigm, specifically that—(1) GWG is modifiable through diet and physical activity; (2) optimal GWG and risk of excess GWG, vary by pre-pregnancy body mass index (BMI) category and (3) the association between GWG and adverse pregnancy outcomes is causal. Using data from three large, harmonized randomized controlled trials (RCTs) of interventions to limit GWG and improve pregnancy outcomes and with appropriate regression models, we investigated the link between diet and physical activity and GWG; the relationships between pre-pregnancy BMI, GWG and birth weight z-score; and the evidence for a causal relationship between GWG and pregnancy outcomes. We found little evidence that diet and physical activity in pregnancy affected GWG and that the observed relationships between GWG and adverse pregnancy outcomes are causal in nature. Further, while there is evidence that optimal GWG may be lower for women with higher BMI, target ranges defined by BMI categories do not accurately reflect risk of adverse outcomes. Our findings cast doubt upon current advice regarding GWG, particularly for overweight and obese women and suggest that a change in focus is warranted.

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