Short-term Dehydroepiandrosterone Intake and Supramaximal Exercise in Young Recreationally-trained Women

2018 ◽  
Vol 39 (09) ◽  
pp. 712-719 ◽  
Author(s):  
Nicolas Gravisse ◽  
Nancy Vibarel-Rebot ◽  
Zakaria Labsy ◽  
Manh-Cuong Do ◽  
Olivier Gagey ◽  
...  

AbstractWADA has banned dehydroepiandrosterone (DHEA) but its ergogenic effect in female athletes has never been investigated. The aim of this study was to determine whether short-term DHEA intake would improve performance during a supramaximal field exercise in healthy young recreationally trained women. Its impact on body composition, metabolic responses was also measured. Eleven young female volunteers completed four running-based anaerobic sprint tests: just before and after treatment with either oral placebo or DHEA (100 mg/day/28days), following a double-blind and randomized protocol. Bioelectrical impedance assessed body composition. At rest and after passive recovery, blood samples were collected for lactate measurement and saliva samples for DHEA, testosterone and cortisol analysis. There was no significant difference in body composition or performance parameters after DHEA administration, despite a tendency toward increased peak power and decreased fat mass. However, DHEA treatment induced a very marked increase in saliva DHEA and testosterone concentrations (p<0.001), with no change in cortisol or lactate levels. In conclusion, short-term DHEA administration did not improve performance or have an anabolic effect in young female recreationally trained athletes, despite the increase in androgenic hormones. Further studies are needed to determine whether a higher daily dose would generate an ergogenic effect during anaerobic exercise.

1999 ◽  
Vol 87 (3) ◽  
pp. 1114-1122 ◽  
Author(s):  
Willa C. Fornetti ◽  
James M. Pivarnik ◽  
Jeanne M. Foley ◽  
Justus J. Fiechtner

The purpose of this investigation was to determine the reliability and validity of bioelectrical impedance (BIA) and near-infrared interactance (NIR) for estimating body composition in female athletes. Dual-energy X-ray absorptiometry was used as the criterion measure for fat-free mass (FFM). Studies were performed in 132 athletes [age = 20.4 ± 1.5 (SD) yr]. Intraclass reliabilities (repeat and single trial) were 0.987–0.997 for BIA (resistance and reactance) and 0.957–0.980 for NIR (optical densities). Validity of BIA and NIR was assessed by double cross-validation. Because correlations were high ( r = 0.969–0.983) and prediction errors low, a single equation was developed by using all 132 subjects for both BIA and NIR. Also, an equation was developed for all subjects by using height and weight only. Results from dual-energy X-ray absorptiometry analysis showed FFM = 49.5 ± 6.0 kg, which corresponded to %body fat (%BF) of 20.4 ± 3.1%. BIA predicted FFM at 49.4 ± 5.9 kg ( r = 0.981, SEE = 1.1), and NIR prediction was 49.5 ± 5.8 kg ( r = 0.975, SEE = 1.2). Height and weight alone predicted FFM at 49.4 ± 5.7 kg ( r = 0.961, SEE = 1.6). When converted to %BF, prediction errors were ∼1.8% for BIA and NIR and 2.9% for height and weight. Results showed BIA and NIR to be extremely reliable and valid techniques for estimating body composition in college-age female athletes.


2005 ◽  
Vol 133 (4) ◽  
pp. 538-543 ◽  
Author(s):  
L. Klimek ◽  
T. Mewes ◽  
H. Wolf ◽  
I. Hansen ◽  
J. Schnitker ◽  
...  

BACKGROUND: The efficacy and safety of short-term immunotherapy with molecular standardized allergens (STI) has been demonstrated by double-blind placebo-controlled clinical trials. The aim of this study was to compare STI with symptomatic drug treatment. METHODS: Forty-eight patients with rhinoconjunctivitis to grass and/or rye pollen were treated either with STI (ALK7, n = 24) plus anti-allergic drugs or anti-allergic drugs, alone (n = 24) in a prospective, randomized study. Symptoms and use of drugs were reported in patient diaries and titrated nasal provocation and skin prick tests were performed at baseline, before, and after season. RESULTS: Median overall symptom ( P = 0.022, U test) and medication scores ( P = 0.003) were significantly lower in the STI group, as was the result for a simultaneous analysis of conjunctival, nasal, and bronchial symptom scores and medication ( P = 0.005). Sensitivity in the nasal provocation test decreased in the STI group but not in the drug-treated group. These differences became significant directly after STI ( P = 0.027) as well as after the grass pollen season ( P < 0.001). Skin sensitivity did not change in the STI group but increased in the drug-treated group after season, with a significant difference between the two groups for the erythema ( P < 0.001). CONCLUSIONS: STI reduces grass pollen-induced rhinoconjunctivitis symptoms and drug use, and specific nasal reactivity and skin sensitivity, more efficiently than a standard symptomatic treatment.


1995 ◽  
Vol 15 (5_suppl) ◽  
pp. 59-62 ◽  
Author(s):  
Sharon Stall ◽  
Nancy S. Ginsberg ◽  
Robert I. Lynn ◽  
Paul M. Zabetakis

There exists an imperative to monitor changes in body composition in all dialysis patients on a regular basis to avoid overt malnutrition. In this regard, the absolute measurement of the fat-free mass assessment may not be as crucial as the serial measurement of fat-free mass with the same modality. A significant difference in measured fat and fat-free mass should be expected if different techniques are employed. Therefore, when attempting to monitor patients over time or to assess the effects of changes in therapeutic regimens, a single methodology should be employed. Our data validate the use of BIA in the stable PD patient, indicating that BIA can predict the DXA results. Considering the ease with which BIA measurements can be obtained and the lack of dependency on operator interpretation, BIA is an ideal technique for use in the clinical setting. The applicability of this technique for use in monitoring longitudinal changes in body composition has, in fact, been well established (25,30,31). BIA appears to be an excellent method for routine fat-free mass measurement in dialysis patients. In as much as malnutrition continues to remain a significant problem in PD patients, measuring and monitoring body composition is strongly recommended.


2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S435-S435
Author(s):  
M Bletsa ◽  
A Karachaliou ◽  
G Kokkotis ◽  
M M Tsoutska ◽  
S Andoniadi ◽  
...  

Abstract Background Inflammatory bowel disease (IBD) has been traditionally associated with malnutrition and increased prevalence of underweight status. Nevertheless, according to recent reports, there appears to be an increase in the percentage of overweight individuals among patients with Crohn’s disease (CD) or ulcerative colitis (UC). In the present study, we aimed to evaluate the body composition of a cohort of Greek patients with IBD. Methods We analysed data from 88 patients with IBD (CD:58, UC:30, female: 45). Body mass index (BMI) was calculated and waist circumference (WC) was measured in all participants. Body composition was evaluated with a multi-frequency bioelectrical impedance segmental body composition analyser (BIA) (Tanita MC-780) and with dual-energy X-ray absorptiometry (DXA). Results 9.1% (n = 8) of patients had low BMI (&lt;18.5), 53.4% (n = 47) normal, 22.7% (n = 20) were overweight and 14.8% (n = 13) obese. No differences were seen between CD vs. UC. Furthermore, 27.3% (n = 24) of women had WC &lt; 80 cm and 27.3% (n = 24) of men had &lt; 94 cm. Referring to % total body fat, as reported by BIA, 46.5% (n = 20) of men and 11.1% (n = 5) of women had total body fat &lt;20%, 46.5% (n = 20) of men and 44.4% (n = 20) of women had 21–30%, 7% (n = 3) of men and 28.9% (n = 13)of women 31–40% and 15.6% (n = 7)of women &gt;41%. According to DXA measurements, 25.6% (n = 11) of men had total body fat &lt;20%, 46.5% (n = 20) of men and 15.6% (n = 7) of women had 21–30%, 25.6% (n = 11) of men and 46.7% (n = 21) of women 31–40% and 2.3% (n = 1) of men and 37.8% (n = 17) of women &gt;41%. There was no significant difference in % total body fat between CD and UC patients in either measurement. We observed a significant difference between the two methods regarding the estimation of % body fat, as BIA measurements were lower than those obtained with DXA (p &lt; 0.001, median = 5.53%, 95% confidence interval = 4.82–6.24%). Nevertheless there was a significant correlation between BIA and DXA measurements in the same individual (r2 = 0.9025, p &lt; 0.001). Conclusion We found a large proportion of overweight/obese patients in our IBD cohort. The association with increased WC may imply that the total abdominal fat is increased in such patients. As excessive fat content has been shown to negatively affect IBD patients in multiple ways, our results emphasise the need for better assessment of body composition and dietetic interventions in this population.


2021 ◽  
Vol 9 ◽  
Author(s):  
David J. Farbo ◽  
Deborah J. Rhea

Background: Body mass index (BMI) is frequently labeled as “flawed” in assessing obesity since it cannot differentiate between muscle and fat leading to misclassifications of healthy individuals. Bioelectrical impedance analysis (BIA) may be a more accurate indicator of obesity since it can distinguish the difference between muscle and fat in children. This pilot study investigated discrepancies between BMI and BIA body composition classifications in children with high levels of physical activity.Methods: Participants were selected from three elementary schools (N = 380, K = 76, 1st = 64, 2nd = 62, 3rd = 61, 4th = 83, and 5th = 34) receiving 60 min of outdoor, unstructured play daily. BIA scales were used to collect each child's body fat percentage and BMI score, then those numbers were categorized by BIA and BMI normative values as either underweight, healthy, overweight, or obese.Results: Overall, 26% of the students were classified differently when using the normative classifications for BMI and BIA, with the largest discrepancy found in the overweight category at 38%. Similar inconsistencies were found when students were divided as younger (42%) vs older students (36%), and males (40%) vs. females (35%).Conclusions: This pilot study demonstrated that there is a significant difference in how BMI and BIA discriminate between the different body composition categories. BIA consistently shows to be a more accurate tool in assessing obesity rates in children since it directly measures body fat.


2021 ◽  
Vol 27 (2) ◽  
pp. 156-160
Author(s):  
Carlos Alencar Souza Alves Junior ◽  
Mikael Seabra Moraes ◽  
Cassiano Schuaste de Souza ◽  
Giovani Costa ◽  
Diego Augusto Santos Silva

ABSTRACT Introduction: The assessment of body composition in female athletes of different sports is important for health monitoring. Objective: To compare body composition in university athletes of different team sports (indoor soccer, flag football and volleyball). Methods: A cross-sectional study carried out with 45 female athletes, aged 18 to 35 years (22.8 ± 3.55). The dependent variables were body fat mass (FM) and fat-free mass (FFM) measured by air displacement plethysmography. Bone mineral content, adjusted for height (BMC/height) and bone mineral density (BMD), were measured by dual energy X-ray absorptiometry. The independent variable was sport [flag football (n = 12); indoor soccer (n = 20); volleyball (n = 13)] and the covariates were age (complete years), training volume (minutes per week) and length of time playing the sport (complete years). Analysis of covariance was used. Results: Adjusting the model for covariates, volleyball athletes (19.27 kg ± 2.20) presented higher FM values compared to the flag football (16.00 kg ± 1.70) and indoor soccer players (12.20 kg ± 1.30). There was no significant difference in FFM, BMC/height and total BMD between sports, even after adjusting for covariates. Conclusion: Volleyball athletes presented higher FM compared to flag football and indoor soccer athletes. There were no differences in FFM, BMC/height and BMD among the players of the different team sports. This study can help coaches and other sports professionals to prevent injuries to athletes in sports such as higher FM (volleyball), or to prevent diseases such as menstrual irregularities, which are common in athletes who may have low levels of body fat (indoor soccer players), this being one of the risk factors for the female athlete triad (eating disorders, menstrual irregularities and low BMD). Level of evidence III; Retrospective comparative study .


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