scholarly journals Recommendations of the AGG (Task Force for Obstetrics, Section Maternal Diseases) on the Management of Maternal Hepatitis B, C and D Infection in Pregnancy

2021 ◽  
Vol 81 (04) ◽  
pp. 390-397
Author(s):  
Maritta Kühnert ◽  
Sven Kehl ◽  
Ulrich Pecks ◽  
Ute Margaretha Schäfer-Graf ◽  
Tanja Groten ◽  
...  

AbstractThese statements and recommendations should provide appropriate information about maternal and fetal routes of infection, screening, detection of risk factors, diagnostic procedures, treatment, birth planning and peripartum and postpartum management of maternal hepatitis infection and offer pointers for prenatal counselling and routine clinical care on delivery wards.

Author(s):  
Arti Sharma ◽  
Shubhra Agarwal ◽  
Garima Bajpai ◽  
Anupriya Singh ◽  
Nikita Agarwal ◽  
...  

Background: Viral hepatitis is the most common liver disease in pregnancy and is also the most common cause of jaundice in pregnancy in tropical countries. Risk factors for transmission are intravenous drug abuse, surgical and dental procedures done without adequate sterilization of instruments, sexual route etc. Early diagnosis and management can prevent maternal and fetal complications. This study was done to evaluate the frequency, risk factors and pregnancy outcome in hepatitis B virus (HBV) and hepatitis C virus (HCV) positive antenatal women.Methods: This case control study was conducted in Teerthankar Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India from January 2017 to June 2018 on total 2511 pregnant women. The serum samples were checked for presence of hepatitis B surface antigen (HBsAg) and presence of IgG antibodies to HCV. Analysis of sociodemographic profile, risk factors and pregnancy outcome were done in all HBV and HCV positive women.Results: Out of 2511 pregnant women, 292 were tested positive for hepatitis. Maximum number of women were in the age group of 21-30 years. Most of the seropositive women were multipara. Frequency of positivity was maximum for HCV (67.1%). The risk factors for transmission in study population were intravenous drug abuse, blood transfusion, history of surgery and tattooing.Conclusions: Hepatitis infection rate is increasing. Universal screening for HBV and HCV can be recommended in pregnant women in developing countries. Education and awareness of public and health care workers can reduce the risk of transmission. 


2012 ◽  
Vol 23 (7) ◽  
pp. 5-6 ◽  
Author(s):  
K J Quinn ◽  
E J Mccarty ◽  
W M Dinsmore ◽  
S P Quah

Co-infection with HIV-1 and -2 is rare, even in west Africa. We present the case of a 38-year-old pregnant Jehovah's Witness presenting late in pregnancy with triple infection with HIV-1, HIV-2 and hepatitis B virus. There was a successful outcome in averting vertical transmission despite objections to management based on religious and cultural beliefs.


2020 ◽  
Vol 15 (17) ◽  
pp. 1679-1688
Author(s):  
James Clark-Wright ◽  
Pollyanna Hudson ◽  
Conor McCloskey ◽  
Stuart Carroll

Aim: An overview of recent epidemiology and disease burden, independent of patient age, of diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis and Hemophilus influenzae invasive disease in the UK. Materials & methods: A systematic review was undertaken. Outcomes included incidence, prevalence, risk factors and cost burden. Results: 39 publications were included. Hepatitis B prevalence is high among certain risk groups. A small pertussis risk remains in pregnancy and for infants, which led to the introduction of maternal vaccination. H. influenzae invasive disease cases are limited to rare serotypes. Polio, tetanus and diphtheria are well controlled. Conclusion: The evaluated diseases are currently well controlled, thanks to a comprehensive vaccination program, with a generally low clinical and cost burden.


2015 ◽  
Vol 2 (1) ◽  
pp. 9-15
Author(s):  
Riaz Gul ◽  
Ahmad Zeb ◽  
Naila Sher

The main objective of the study was to determine the frequency of hepatitis B and hepatitis C in hemodialysis dependent patients who are positive for either type of hepatitis infection.Methodology:Study was conducted for duration of five months (1st Dec 2014- 23rd April 2015) at nephrology unit of Khyber teaching hospital and kidney center of Hayat Abad medical complex. Patients who were dependent on dialysis with renal failure due to any cause were targeted for the study. All patients who were found positive for either type of hepatitis infection were included in the study. All patients who were positive with hepatitis infection before the start of dialysis and those who came for the first time for dialysis were excluded from the study.A semi structured questionnaire with both open and close ended questions was used to collect the information from the patients. Written consent was taken from all the patients prior to the data collection after explaining purpose of the study. It was a cross sectional study and non-probability convenient sampling technique was adopted for the data collection. Total of hundred patients who were positive for hepatitis were taken as sample size. Patient’s record was also thoroughly checked as an adding tool for data collection. Apart from patients some inquiry was also done from the concerned staff working on dialysis machines.Results:Results of this study show that the prevalence of hepatitis infection is more in dialysis dependent patients as compared to the general population, and that among the positive cases the frequency of hepatitis C was more than hepatitis B. Common risk factors associated with increase prevalence of hepatitis infection among hemodialysis dependent patients are frequent blood transfusion without proper screening, lack of proper sterilization of dialysis machine and environment where dialysis is carried out. Close proximity of the patients with positive cases of hepatitis positive patients, previous surgical procedures carried out, history of hepatitis infection in family and decreased immunity of the dialysis patientsConclusions:Frequent dialysis leads to increase frequency of hepatitis C as compared to hepatitis B and unsterilized environment of the area around the machine and unscreened blood transfusion are the major contributors.


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