scholarly journals Mental Comorbidity in Rheumatic Diseases

2021 ◽  
Author(s):  
Olga Seifert ◽  
Christoph Baerwald

AbstractIn this review, we summarise the most relevant studies in a PubMed Search term “mental disorders and rheumatic disease” in the last 15 years. Mental disorders such as depression and anxiety are common in people with rheumatic diseases. Treating these comorbidities can improve the patientʼs quality of life. The high prevalence of symptoms of psychiatric disorders is a challenge for rheumatologists, especially with regard to the differentiation of possible psychiatric components in rheumatological diseases. Screening for psychiatric problems in patients with rheumatic diseases should be evaluated as soon as possible, as these can have a major influence on the perception of pain and physical functioning status from the outset. Mental health disorders are seen as a risk factor for poor patient outcomes, as patients may not adhere to medical treatments. The potential side effects of biological agents can increase patient anxiety and affect adherence to therapy. Therefore, interdisciplinary care would be of great advantage in the treatment of rheumatic patients with psychological comorbidities.

Author(s):  
Maheen Nisar

Rapid progress is being made in the development of next-generation sequencing (NGS) technologies, allowing repeated findings of new genes and a more in-depth analysis of genetic polymorphisms behind the pathogenesis of a disease. In a field such as psychiatry, characteristic of vague and highly variable somatic manifestations, these technologies have brought great advances towards diagnosing various psychiatric and mental disorders, identifying high-risk individuals and towards more effective corresponding treatment. Psychiatry has the difficult task of diagnosing and treating mental disorders without being able to invariably and definitively establish the properties of its illness. This calls for diagnostic technologies that go beyond the traditional ways of gene manipulation to more advanced methods mainly focusing on new gene polymorphism discoveries, one of them being NGS. This enables the identification of hundreds of common and rare genetic variations contributing to behavioral and psychological conditions. Clinical NGS has been useful to detect copy number and single nucleotide variants and to identify structural rearrangements that have been challenging for standard bioinformatics algorithms. The main objective of this article is to review the recent applications of NGS in the diagnosis of major psychiatric disorders, and hence gauge the extent of its impact in the field. A comprehensive PubMed search was conducted and papers published from 2013-2018 were included, using the keywords, “schizophrenia” or “bipolar disorder” or “depressive disorder” or “attention deficit disorder” or “autism spectrum disorder” and “next-generation sequencing”


2019 ◽  
Vol 11 (2S) ◽  
pp. 17-24
Author(s):  
B. A. Volel ◽  
D. S. Petelin ◽  
D. O. Rozhkov

Chronic back pain is a significant biomedical problem due to its high prevalence and negative impact on quality of life and socioeconomic indicators. Mental disorders play a substantial role in the genesis of chronic pain. This review discusses the issues of back pain comorbid with depressive, anxiety disorders, post-traumatic stress disorder, and somatoform disorder. It also considers the features of the clinical manifestations of pain associated with mental disorders. There are data on the neurobiological relationship between pain and mental disorders and on the personality traits of patients with chronic back pain.


2021 ◽  
Author(s):  
Nayane Miranda Silva ◽  
Rebeca da Nobrega Lucena Pinho ◽  
Thais Ferreira Costa ◽  
Adriana Ferreira Barros Areal ◽  
André De Mattos Salles ◽  
...  

BACKGROUND The coronavirus (SARS-CoV-2) epidemic was first identified in Wuhan, China, at the end of 2019, and spread across the world in a fast and disordered manner. Because of the pandemic, health professionals, including residents in medicine and other health specialties, began working under intense physical and psychological pressure daily and were exposed to a greater risk of developing mental disorders and psychological distress. OBJECTIVE This study evaluated the prevalence of symptoms indicative of mental disorders such as depression, anxiety and stress among postgraduate students who were residents in medicine and other health specialties during the COVID-19 pandemic in Brazil and identified possible associated predisposing factors. METHODS This was a cross-sectional study that included postgraduate students in medical and other health residency programmes in Brazil. The recruitment period was from July 29 to September 5, 2020. Epidemiological and clinical data, including evaluations of psychological and affective aspects, following a predefined protocol, were collected after the participants filled out an electronic form via the Microsoft Forms platform. RESULTS In total, 1,313 medical and other health residents participated in the study. The Depression, Anxiety and Stress Scale-21 (DASS-21) identified depression, anxiety and stress in 51.3%, 53.4% and 52.6% of the participants, respectively. Based on the Brief Resilient Coping Scale (BRCS), 61.9% of the participants had low resilience. A total of 60.9% of the residents had high scores on the Patient Health Questionnaire 9‐item depression module (PHQ-9). CONCLUSIONS We found a high prevalence of symptoms of depression, anxiety and stress among medical and non-medical residents during the COVID-19 pandemic in Brazil. Mental disorders are complex in nature, and the particular academic environment of residency, altered by the need to care for patients with COVID-19, can be a potential stressor and be associated with the high prevalence of these symptoms among residents. INTERNATIONAL REGISTERED REPORT RR2-10.2196/24298


1981 ◽  
Vol 11 (3) ◽  
pp. 561-579 ◽  
Author(s):  
Paul Bebbington ◽  
Jane Hurry ◽  
Christopher Tennant ◽  
Elizabeth Sturt ◽  
J. K. Wing

SYNOPSISA two-stage psychiatric survey of a random sample of adults aged 18–64 from Camberwell is described. Agency interviewers carried out the first stage (N = 800), using the shorter form of the Present State Examination (PSE). MRC interviewers, using the full PSE, saw a stratified sample of these (N = 310) in the second stage. A second interview was sought with all those of Index of Definition (ID) level 5 and above at the first interview (‘cases’) and with a random sample of those below that level. 20·9% refused or were never available for the first interview. Of the 800 subjects successfully interviewed, 10% refused a further interview and 12·4% of those finally selected for this interview were either unavailable or changed their minds. The MRC data, weighted to represent the whole sample, are used in our analyses. The prevalence of psychiatric disorder as defined in our study was calculated at 6·1% for men and 14·9% for women. Women shared a higher prevalence of disorder in the age-groups 25–34 and 45–54, but in men there was no significant association with age.In contrast to the findings of Brown & Harris (1978), social class did not have a strong association with disorder. Single men had much higher rates than married men, while the reverse was true in women. In both sexes employment was associated with lower rates of disorder. An attempt to explain the high prevalence in women in terms of their role in marriage and child-care was only partly successful.


2011 ◽  
Vol 199 (6) ◽  
pp. 443-444 ◽  
Author(s):  
Anthony F. Jorm

SummaryA national survey in 1997 found that Australia had a high prevalence of mental disorders with low rates of treatment. Since then, treatment availability has increased greatly and unmet need has reduced. However, there is little evidence that the nation's mental health has improved.


2016 ◽  
Vol 1 (1) ◽  
pp. 010106
Author(s):  
Iryna Frankova ◽  
Polina Krasnova

Mental illness - is a heavy burden of modern society and may be underestimated. There are several reasons: the high prevalence of this category of disorders, high level of stigmatization, treatment gap between those who are mentally ill and those will be treated. The economic crisis and the lack of resources, make psychosocial rehabilitation of mental disorders even more complicated. This review is based on materials of the 24th Congress of the European Psychiatric Association (April 2016, Madrid), the participants of the "Eastern European Academy of the World Psychiatric Association and "Servier" company specifically for psychiatric journals of WPA Zone 10 (East European Educational WPA-Servier Academy - «EEE WPA-Servier Academy». The review will present materials from several symposiums: "Psychosocial rehabilitation and mental health", "Overcoming the stigma of mental disorders: recent advances and initiatives," "Fight stigma: a global challenge", and state-of-the-art report, "Psychosocial interventions in schizophrenia».


2021 ◽  
Vol 10 (3) ◽  
pp. e4810312781
Author(s):  
Angie Patricia Castro-Merán ◽  
Gustavo Moreno Braga ◽  
Eduardo Stedile Fiamoncini ◽  
Bruno Gomes Duarte ◽  
Osny Ferreira Júnior ◽  
...  

Objective: To verify the rate of systemic changes observed in individuals seen at the Oral and Maxillofacial Surgery and Traumatology clinics of the Undergraduate Dentistry course at the Faculty of Dentistry of Bauru (FOB-USP). Methodology: a retrospective study of the medical records of individuals seen at the Oral and Maxillofacial Surgery and Traumatology clinics of the third and fourth years of the Dentistry course at FOB-USP, from January 1, 2015, to June 30, 2017. Data collection was performed based on information from the anamnesis obtained during the initial care of the patients and recorded in the medical records. The selected data were name, age, address, diagnosed systemic disease, current and/or past medical treatments, proposed surgical treatment, and, if there was, patient return after medical treatment for surgery. The medical records of individuals under the age of 18, patients who did not have any systemic changes, or those with systemic changes observed outside the initial care period were excluded. RESULTS: The sample consisted of 266 medical records and 119 of these were from individuals who had systemic changes (44.7%), with systemic arterial hypertension being the most common (33.1%), followed by diabetes mellitus (17.8%). Conclusion: the high prevalence of individuals with systemic alterations and who require dental surgical intervention was proven, which implies the need for a correct anamnesis and preoperative evaluation so that these cases are managed to avoid trans and/or post-operative, systemic, and/or local.


2021 ◽  
Vol 8 ◽  
Author(s):  
Rita Businaro ◽  
David Vauzour ◽  
Jerome Sarris ◽  
Gerald Münch ◽  
Erika Gyengesi ◽  
...  

Emerging evidence is showing nutrition as a crucial factor in the high prevalence and incidence of neurodegenerative mental disorders. Preventive interventions on neuroinflammation seem to be able to interfere with neurodegeneration. Supplementation of essential nutrients, such as long-chain-polyunsaturated fatty acids, vitamin E and mineral elements, may minimize inflammation, enhancing antioxidative defense, and lowering the risk and incidence of age-related diseases, such as cardiovascular diseases and neurodegenerative diseases. This manuscript reviews the current evidence on the role of neuroinflammation in the pathophysiology of neurodegenerative and mental disorders, and preventive strategies for food supplementation in these neuropsychiatric diseases. Dietary supplementation-based strategies have been demonstrated to be effective in subjects with mild cognitive impairment, while weaker results have been obtained in patients with advance neurodegenerative disease. Adjunctive supplementation has also been demonstrated to improve depression, this being of marked benefit considering the comorbidity between cognitive impairment/dementia and depression. Further research is needed to improve the prescriptive precision of supplementation in patients, and to better understand potential interactions with clinical and pharmacokinetic factors.


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