The impact of increased consumption of fruits and vegetables on cortisol and cortisone excretion in 24-h urine of children

2015 ◽  
Vol 122 (03) ◽  
Author(s):  
J Esche ◽  
L Shi ◽  
A Sánchez-Guijo ◽  
MF Hartmann ◽  
S Wudy ◽  
...  
2021 ◽  
pp. 1-24
Author(s):  
Julian Xie ◽  
Ashley Price ◽  
Neal Curran ◽  
Truls Østbye

Abstract Objective: To evaluate a Produce Prescription Programme’s utilisation, and its effects on healthy food purchasing and diabetes control among participants with type 2 diabetes. Design: Prospective cohort study using participants’ electronic health records (EHR) and food transaction data. Participants were categorized as “Frequent Spenders” and “Sometimes Spenders” based on utilisation frequency. Multivariate regressions assessed utilisation predictors; and programme effects on fruit/vegetable purchasing (spending, expenditure share, variety) and on diabetes-related outcomes (HbA1c, BMI, blood pressure). Setting: Patients enrolled by clinics in Durham, North Carolina, USA. Participants received $40 monthly for fruits and vegetables at a grocery store chain. Subjects: 699 food-insecure participants (353 with diabetes). Results: Being female and older was associated with higher programme utilisation; hospitalisations were negatively associated with programme utilisation. Frequent Spender status was associated with $8.77 more in fruit/vegetable spending (p < 0.001), 3.3% increase in expenditure share (p = 0.007), and variety increase of 2.52 fruits and vegetables (p < 0.001). For $10 of Produce Prescription Dollars spent, there was an $8.00 increase in fruit/vegetable spending (p < 0.001), 4.1% increase in expenditure share, and variety increase of 2.3 fruits/vegetables (p < 0.001). For the 353 participants with diabetes, there were no statistically significant relationships between programme utilisation and diabetes control. Conclusions: Programme utilisation was associated with healthier food purchasing, but the relatively short study period and modest intervention prevent making conclusions about health outcomes. Produce Prescription Programmes can increase healthy food purchasing among food-insecure people, which may improve chronic disease care.


2021 ◽  
Vol 10 (7) ◽  
pp. 1490
Author(s):  
Ana Reis ◽  
Sara Rocha ◽  
Victor de Freitas

During the 20th century processed and ready-to-eat foods became routinely consumed resulting in a sharp rise of fat, salt, and sugar intake in people’s diets. Currently, the global incidence of obesity, raised blood lipids, hypertension, and diabetes in an increasingly aged population contributes to the rise of atherothrombotic events and cardiovascular diseases (CVD) mortality. Drug-based therapies are valuable strategies to tackle and help manage the socio-economic impact of atherothrombotic disorders though not without adverse side effects. The inclusion of fresh fruits and vegetables rich in flavonoids to human diets, as recommended by WHO offers a valuable nutritional strategy, alternative to drug-based therapies, to be explored in the prevention and management of atherothrombotic diseases at early stages. Though polyphenols are mostly associated to color and taste in foods, food flavonoids are emerging as modulators of cholesterol biosynthesis, appetite and food intake, blood pressure, platelet function, clot formation, and anti-inflammatory signaling, supporting the health-promoting effects of polyphenol-rich diets in mitigating the impact of risk factors in atherothrombotic disorders and CVD events. Here we overview the current knowledge on the effect of polyphenols particularly of flavonoid intake on the atherothrombotic risk factors and discuss the caveats and challenges involved with current experimental cell-based designs.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 959-959
Author(s):  
Mary Greaney ◽  
Zachary Kunicki ◽  
Megan Drohan ◽  
Steven Cohen

Abstract The population of older adults aged 65+ in the US is projected to increase from 15% to 21% in the next 30 years. Aging in place provides cost-savings and familiarity to the older adult, but often requires informal caregivers. Informal caregivers, individuals who provide unpaid care of assistance to family members and friends may have been uniquely impacted by the COVID-19 pandemic and shelter-at-home orders. Research is needed to examine how the pandemic impacted caregivers’ caregiving responsibilities and health behaviors (e.g., physical activity, sedentary time, fruit and vegetable intake, snacking, etc.) as this information will be invaluable to determine if health promotion interventions are needed for informal caregivers. Self-reported data were gathered from informal caregivers providing care to someone aged 50+ (n=835) through Amazon’s Mechanical Turk. Respondents reported their current and pre-pandemic health behaviors and demographics. Chi-square tests were used to examine bivariate associations between pandemic time (pre vs. post) and each examined behavior. The analysis identified some positive health behavior changes due to the pandemic: caregivers felt since the pandemic they ate more fruits and vegetables (p &lt; .001), walked more, exercised more (p &lt; .001), increased amounts of sleep (p &lt; .001), and higher sleep quality (p &lt; .001). However, respondents also had more screen time (p &lt; .001) and sedentary time (p &lt; .001). Future planned analyses will focus on examining whether these changes were consistent across all sociodemographic subgroups of caregivers and whether they persist after the pandemic recedes.


Water ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 555 ◽  
Author(s):  
Paola Sánchez-Bravo ◽  
Jacinta Collado-González ◽  
Mireia Corell ◽  
Luis Noguera-Artiaga ◽  
Alejandro Galindo ◽  
...  

Water, especially in arid and semiarid regions, is increasingly a disputed commodity among different productive sectors; the pressure for a more sustainable use of water in agriculture will grow. The main strategy to cope with water scarcity is the use of improved, innovative, and precise deficit irrigation management practices which are able to minimize the impact on fruit yield and quality. The aim of this paper was to develop a certification index or hydroSOS quality index for extra virgin olive oil and processed table olives. The hydrosSOS fruits and vegetables are those cultivated under regulated deficit irrigation (RDI). Different indicators in three quality areas ((i) fatty acids, (ii) phenolic compounds, and (iii) sensory attributes) were identified as showing characteristic or typical responses under RDI conditions. Marks or scores were assigned to each one of these indicators to calculate the proposed index. It can be concluded that an extra virgin olive oil (EVOO) or processed table olives are hydroSOStainable foods, if they meet 2 conditions: (i) fulfill the conditions established in the hydroSOS “irrigation” index, and (ii) fulfill the requirements of the hydroSOS “quality” index. HydroSOS quality index will be specific to each crop and variety and will depend on functional and sensory factors.


Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Yan Li ◽  
David S Siscovick ◽  
Donglan Zhang ◽  
José A Pagán

Introduction: Consumption of fruit and vegetables is associated with a lower risk of obesity, diabetes, hypertension, and cardiovascular disease . While five or more servings of fruits and vegetables are recommended, only 50% of residents of New York City (NYC) consume two or more servings a day. While food marketing can change individual dietary behaviors, there is limited evidence on the extent to which healthy food marketing strategies—such as community-based and mass-media campaigns—influence fruit and vegetable consumption at the neighborhood level. Agent-based modeling (ABM) has the potential to provide new insights on how healthy food marketing may impact dietary behaviors by simulating interventions, consumption decisions, and interactions among people in different contexts. Hypothesis: Healthy food marketing significantly increases consumption of fruit and vegetables in NYC neighborhoods. The impact of healthy food marketing varies across different neighborhoods depending on population characteristics and the local food environment. Methods: We developed an ABM that takes into account individual and neighborhood-level factors (e.g., age, gender, education, food environment) and influences of social networks (peers, friends, and family) to predict dietary behaviors of individuals at the neighborhood level. Model parameters were estimated from the Food Attitudes and Behaviors Survey, United States Census data, and previous studies. Healthy food marketing can strengthen positive social norms with regard to dietary behaviors. We simulated two hypothetical healthy food marketing interventions that could improve the influence of positive social norms by 5% and 10%, respectively. We predicted the impact of these interventions on the proportion of the population who consume two or more servings of fruits and vegetables across 34 NYC neighborhoods (defined by the United Hospital Fund) in three years. We validated our model using data from the NYC Community Health Survey. Results: The simulation results suggested that the healthy food marketing interventions have the potential to increase the proportion of the population who consume two or more servings of fruits and vegetables over three years: for a 5% improvement on positive social norms, the increase in the proportion was 0.58% - 8.97% by neighborhood; and for a 10% improvement on positive social norms, 2.68% - 13.94% by neighborhood. Exploratory analyses suggested that among population characteristics, a high proportion of population without a high school diploma was associated with lower effectiveness of healthy food marketing in increasing consumption of fruits and vegetables. Conclusions: Healthy food marketing may increase consumption of fruits and vegetables in NYC, but more attention to the mechanisms that account for the lower increase in neighborhoods with low educational attainment is needed.


2021 ◽  
Vol 12 ◽  
Author(s):  
Katie Clarke ◽  
Suzanne Higgs ◽  
Clare E. Holley ◽  
Andrew Jones ◽  
Lucile Marty ◽  
...  

Previous research suggests that exposure to nature may reduce delay discounting (the tendency to discount larger future gains in favor of smaller immediate rewards) and thereby facilitate healthier dietary intake. This pre-registered study examined the impact of online exposure to images of natural scenes on delay discounting and food preferences. It was predicted that exposure to images of natural scenes (vs. images of urban scenes) would be associated with: (i) lower delay discounting; (ii) higher desirability for fruits and vegetables (and lower desirability for more energy-dense foods); and (iii) delay discounting would mediate the effect of nature-image exposure on food desirability. Adult participants (N = 109) were recruited to an online between-subjects experiment in which they viewed a timed sequence of six images either showing natural landscape scenes or urban scenes. They then completed measures of mood, delay discounting (using a five-trial hypothetical monetary discounting task) and rated their momentary desire to eat four fruits and vegetables (F&amp;V), and four energy-dense foods. There was no statistically significant effect of experimental condition (natural vs. urban image exposure) on delay discounting or food desirability. Bayes factors supported the null hypothesis for discounting (BF01 = 4.89), and energy-dense food desirability (BF01 = 7.21), but provided no strong evidence for either hypothesis for F&amp;V desirability (BF01 = 0.78). These findings indicate that brief online exposure to images of nature does not affect momentary impulsivity or energy-dense food preference, whereas for preference for less-energy dense foods, the evidence was inconclusive.


Antioxidants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1906
Author(s):  
Mayada R. Farag ◽  
Attia A. A. Moselhy ◽  
Amany El-Mleeh ◽  
Samira H. Aljuaydi ◽  
Tamer Ahmed Ismail ◽  
...  

Doxorubicin (DOX) is a chemotherapeutic agent against hematogenous and solid tumors with undesirable side effects including immunosuppression. Quercetin (QUR), a natural flavonoid abundant in fruits and vegetables, has a potent antioxidant activity. The aim of the current study was to assess the impact of QUR on DOX-induced hematological and immunological dysfunctions in a rodent model. Randomly grouped rats were treated as follows: control, QUR alone (50 mg/kg for 15 days per os), DOX alone (2.5 mg/kg I/P, three times a week, for two weeks), and co-treated rats with QUR for 15 days prior to and concomitantly with DOX (for two weeks), at the doses intended for groups two and three. DOX alone significantly disrupted the erythrogram and leukogram variables. Serum immunoglobulin (IgG, IgM, and IgE) levels and the activities of catalase (CAT) and superoxide dismutase (SOD) and in spleen were declined. The DNA damage traits in spleen were elevated with an upregulation of the expression of the apoptotic markers (p53 and Caspase-3 genes) and the proinflammatory cytokines (IL-6 and TNF-α genes), while the expression of CAT gene was downregulated. These biochemical changes were accompanied by morphological changes in the spleen of DOX-treated rats. Co-treatment with QUR abated most of the DOX-mediated alterations in hematological variables, serum immunoglobulins, and spleen antioxidant status, pro-inflammatory and apoptotic responses, and histopathological alterations. In essence, these data suggest that QUR alleviated DOX-induced toxicities on the bone marrow, spleen, and antibody-producing cells. Supplementation of chemotherapy patients with QUR could circumvent the DOX-induced inflammation and immunotoxicity, and thus prevent chemotherapy failure.


2014 ◽  
Vol 26 (12) ◽  
pp. 2735-2749 ◽  
Author(s):  
Nina S. Hsu ◽  
Margaret L. Schlichting ◽  
Sharon L. Thompson-Schill

Many features can describe a concept, but only some features define a concept in that they enable discrimination of items that are instances of a concept from (similar) items that are not. We refer to this property of some features as feature diagnosticity. Previous work has described the behavioral effects of feature diagnosticity, but there has been little work on explaining why and how these effects arise. In this study, we aimed to understand the impact of feature diagnosticity on concept representations across two complementary experiments. In Experiment 1, we manipulated the diagnosticity of one feature, color, for a set of novel objects that human participants learned over the course of 1 week. We report behavioral and neural evidence that diagnostic features are likely to be automatically recruited during remembering. Specifically, individuals activated color-selective regions of ventral temporal cortex (specifically, left fusiform gyrus and left inferior temporal gyrus) when thinking about the novel objects, although color information was never explicitly probed during the task. Moreover, multiple behavioral and neural measures of the effects of feature diagnosticity were correlated across participants. In Experiment 2, we examined relative color association in familiar object categories, which varied in feature diagnosticity (fruits and vegetables, household items). Taken together, these results offer novel insights into the neural mechanisms underlying concept representations by demonstrating that automatic recruitment of diagnostic information gives rise to behavioral effects of feature diagnosticity.


Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
Patrick J Sur ◽  
Ashkan Afshin

Introduction: While cardio-protective effects of fruits and vegetables are well-established, the impact of their suboptimal intake on the CVD burden across nations and levels of development has not been evaluated. Objective: To systematically quantify the burden of CVD attributable to low intake of fruits and low intake of vegetables in 195 countries by age, sex, country, and development status in 2015. Methods: We obtained data on consumption of fruits and vegetables from nationally or subnationally representative nutrition surveys and data on their national availability from the UN FAO. Etiologic effect sizes of fruits and vegetables on CVD endpoints were obtained from meta- analyses of prospective cohort studies. The optimal level of intakes for each was determined based on the levels associated with lowest risk of mortality in prospective observational studies. A comparative risk assessment analysis was conducted to quantify the proportion of disability- adjusted life years (DALYs) attributable to low intake of each. The variation of this burden was further evaluated across different levels of our newly developed socio-demographic index (SDI). Results: In 2015, low intake of fruits accounted for 57.3 (95% UI: 37.1- 78.4) million DALYs due to CVD globally (41.5% from IHD and 58.5% from stroke). Low intake of vegetable caused 44.6 (23.6- 68.8) million CVD DALYs (67.3% IHD and 32.7% stroke). The highest burden of CVD attributable to low intake of fruits and vegetables was seen in the middle and low-middle SDI quintiles (17.2 and 14.3% of total DALYs), while the lowest burden for each was seen in high and high-middle SDI quintiles (12.7 and 11.2%). At the country level, the attributable CVD burden ranged from 5.1% of total DALYs (Rwanda) to 23.2% (Bangladesh) for low intake of fruit and from 5.9% (North Korea) to 19.4% (Mongolia) for low intake of vegetable. Conclusion: Our findings suggest that population inventions to increase consumption of fruits and vegetables at population level could save millions of life years globally. Figure. Age-standardized proportion of disability-adjusted life years attributable to low intake of fruits (A) and vegetables (B) from cardiovascular disease among adults (> 25y) in 2015.


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