Rolandic Epilepsy: Retrospective Analysis of Neuropsychological and Clinical Data

Objectives: To evaluate the spatial distribution of the epileptiform activity in electrical status epilepticus in sleep (ESES) and to correlate data from electroencephalograms (EEGs) with clinical and neuroimaging variables. Methods: From 2008 to 2015, 162 reports (1.01%) out of 16,000 EEGs, from 23 patients, showed ESES. We selected one representative EEG per patient. Clinical data was collected retrospectively. Neuroimaging examinations were reviewed. The EEGs were classified as generalized ESES (ESESg) and focal ESES (ESESf) according to the distribution of epileptiform discharges. Results: From the 23 patients, 5 were classified as ESESg and 18 as ESESf. In ESESf, there was a prevalence of focal epileptic discharges in the centrotemporal regions. Abnormal neuroimaging occurred in 100% of the patients with ESESg and in 38.9% of the patients with ESESf (p=0.037). Other clinical data did not show significant differences between the groups. All patients with ESESg had structural etiology, while only 39% of patients with ESESf had structural etiology and the remaining 61% potentially genetic epilepsies of the rolandic spectrum. Conclusion: ESESg occurred predominantly in patients with structural lesions, while most patients with ESESf had normal neuroimaging scans and electrical dysfunction mainly in the rolandic region. Significance: ESESg seems to occur mostly in structural epilepsies. Distinctly, ESESf occurs in epileptic syndromes within the functional spectrum of rolandic epilepsy.

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PDB29 Glycemic Control and Diabetes-Related Health Care Costs in Type 2 Diabetes. A Retrospective Analysis Based on Administrative and Clinical Data

Value in Health ◽

10.1016/j.jval.2012.08.1672 ◽

2012 ◽

Vol 15 (7) ◽

pp. A498

Author(s):

L. Degli Esposti ◽

S. Saragoni ◽

S. Buda ◽

E. Degli Esposti

Keyword(s):

Type 2 Diabetes ◽

Health Care ◽

Glycemic Control ◽

Retrospective Analysis ◽

Health Care Costs ◽

Clinical Data ◽

Care Costs

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Identifying the Stressors Impacting Rescued Avian Wildlife

Animals ◽

10.3390/ani10091500 ◽

2020 ◽

Vol 10 (9) ◽

pp. 1500

Author(s):

Kimberley Janssen ◽

Crystal Marsland ◽

Michelle Orietta Barreto ◽

Renae Charalambous ◽

Edward Narayan

Keyword(s):

Pilot Study ◽

Retrospective Analysis ◽

Clinical Data ◽

Environmental Stressors ◽

Abnormal Behaviour ◽

Secondary Stressors ◽

Impact Injuries

Urbanisation exposes avian wildlife to an array of environmental stressors that result in clinical admission and hospitalisation. The aim of this pilot study was to conduct a retrospective analysis of clinical data and characterise this based on categories of stress experienced by avian wildlife patients. The results from this study indicated that impact injuries (n = 33, 25%) and vehicle-related injuries (n = 33, 25%) were the most common occurring preliminary stressors that resulted in the hospitalisation of avian wildlife. The most common outcome of avian patients that suffered from vehicle-related injuries was euthanasia (n = 15, 45%), as was avian patients that suffered from impact injuries (n = 16, 48%). Immobility (n = 105, 61%) and abnormal behaviour (n = 24, 14%) were the most commonly occurring primary stressors of avian patients. Finally, trauma (n = 51, 32%) and fractures (n = 44, 27%) were the most common occurring secondary stressors in avian patients. The most common outcome of all these stressors was euthanasia. This study provided further evidence towards the notion that human- and urbanisation-related stressors are the main causes of hospitalisation of avian wildlife, but also indicated that birds admitted as a result of human-related stressors are more likely to be euthanised than released. This study also provided a categorisation system for the stressors identified in avian wildlife patients (preliminary, primary and secondary) that may be used to monitor the stress categories of wildlife patients and gain a deeper understanding of the complex notion of stress.

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Glycopeptidolipid Genotype Correlates With the Severity of Mycobacterium abscessus Lung Disease

The Journal of Infectious Diseases ◽

10.1093/infdis/jiz475 ◽

2020 ◽

Vol 221 (Supplement_2) ◽

pp. S257-S262 ◽

Cited By ~ 1

Author(s):

Bing Li ◽

Meiping Ye ◽

Lan Zhao ◽

Qi Guo ◽

Jianhui Chen ◽

...

Keyword(s):

Lung Disease ◽

Retrospective Analysis ◽

Clinical Data ◽

Clinical Characteristics ◽

Mycobacterium Abscessus ◽

Clinical Isolates ◽

Colony Morphology ◽

Wild Type ◽

Mutant Type ◽

The Relationship

Abstract Background Smooth and rough colony morphotypes of Mycobacterium abscessus are associated with virulence, but some isolates form both smooth and rough colonies, impeding successful morphotype identification. Reportedly, smooth/rough morphotypes are also related to the glycopeptidolipid (GPL) genotype. However, the accuracy of GPL genotyping to discriminate morphotypes and the relationship between GPL genotype and clinical characteristics of M abscessus lung disease have not been verified. Methods A retrospective analysis of colony morphology, GPL genotype, and clinical data from 182 patients with M abscessus lung disease was conducted. Results Of 194 clinical isolates, 126 (65.0%), 15 (7.7%), and 53 (27.3%) exhibited rough, smooth, and mixed colony morphotypes, respectively. Glycopeptidolipid genotyping indicated that 86.7% (13 of 15) of smooth isolates belonged to the GPL-wild type (WT) group, whereas 98.4% (124 of 126) of rough isolates belonged to the GPL-mutant type (MUT) group. Therefore, GPL genotyping accurately distinguished between smooth and rough morphotypes. Mixed colony morphotypes were also divided into GPL-WT (18.9%) and GPL-MUT (81.1%) groups. Further analysis revealed that patients infected with the GPL-MUT group presented with significantly worse baseline clinical characteristics and exacerbated episodes of lung disease. Conclusions Glycopeptidolipid genotyping accurately distinguishes smooth and rough colony morphotypes. Patients infected with the GPL-MUT genotype exhibit worse clinical characteristics and are at a higher risk of exacerbated lung disease.

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Retrospective analysis on thermal injuries in children—Demographic, etiological and clinical data of German and Austrian pediatric hospitals 2006–2015—Approaching the new German burn registry

Burns ◽

10.1016/j.burns.2017.05.013 ◽

2018 ◽

Vol 44 (1) ◽

pp. 150-157 ◽

Cited By ~ 3

Author(s):

Laura C. Tegtmeyer ◽

Georg R. Herrnstadt ◽

Sarah L. Maier ◽

Oliver C. Thamm ◽

Michaela Klinke ◽

...

Keyword(s):

Retrospective Analysis ◽

Clinical Data ◽

Pediatric Hospitals ◽

Thermal Injuries

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Clinical Analysis of 12 Cases of Colon Cancer Postsurgical Gastric Paralysis

Proceedings of Anticancer Research ◽

10.26689/par.v1i2.14 ◽

1970 ◽

Vol 1 (2) ◽

Author(s):

Mingming Su

Keyword(s):

Colon Cancer ◽

Surgical Treatment ◽

Retrospective Analysis ◽

Clinical Data ◽

Metabolic Disorders ◽

Radical Resection ◽

Clinical Analysis ◽

Diagnosis And Treatment ◽

Multiple Factors ◽

Non Surgical Treatment

Objective:Â To explore the causes, diagnosis and treatment ofÂ gastric paralysis after radical resection of colon cancer. Methods:Â A retrospective analysis was performed on the clinical data of 12Â cases of patients with gastroparesis syndrome after colon cancerÂ surgery in our department from January, 2011 to December, 2013.Â Results:Â Gastric paralysis after radical resection of colon cancerÂ is caused by multiple factors and its incidence is linked to factorsÂ like nervous and mental factors, surgical traumas, post-surgicalÂ metabolic disorders and anesthesia drugs and other factors. AllÂ patients are healed with non-surgical treatment. Conclusions:Â Comprehensive and conservative treatments are carried out forÂ gastric paralysis after radical resection of colon cancer andÂ satisfactory curative effects can be obtained. Surgical treatmentÂ should be chosen carefully and considerately.

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