Azazytidin and Vitamin C modulates the expression profile of epigenetic modulators in HepG2 and increase their metabolic function

2018 ◽  
Vol 56 (01) ◽  
pp. E2-E89
Author(s):  
M Ruoß ◽  
G Damm ◽  
S Sajadian ◽  
A Nüssler
2019 ◽  
Vol 70 (10) ◽  
pp. 3711-3713
Author(s):  
Lucretia Anghel ◽  
Liliana Baroiu ◽  
Adrian Beznea ◽  
Gabi Topor ◽  
Camelia Ana Grigore

Maintaining cellular homeostasis in the context of its normal metabolic function is achieved by establishing the balance between its own antioxidant capacity and the level of harmful compounds resulting from the mitochondrial activity and the immune system. One of the antioxidants involved in this process is vitamin E with its most active form - alpha-tocopherol, which exerts its functions through vitamin C. The main functions of this antioxidant are: regulation of platelet aggregation, cellular signaling, antioxidation. The therapeutic relevance of vitamin E has increased due to the incrimination of oxidative stress as a link in the pathophysiology of many chronic diseases. Respectively, the role most targeted is that of antioxidant.


2019 ◽  
Vol 70 (10) ◽  
pp. 3711-3713

Maintaining cellular homeostasis in the context of its normal metabolic function is achieved by establishing the balance between its own antioxidant capacity and the level of harmful compounds resulting from the mitochondrial activity and the immune system. One of the antioxidants involved in this process is vitamin E with its most active form - alpha-tocopherol, which exerts its functions through vitamin C. The main functions of this antioxidant are: regulation of platelet aggregation, cellular signaling, antioxidation. The therapeutic relevance of vitamin E has increased due to the incrimination of oxidative stress as a link in the pathophysiology of many chronic diseases. Respectively, the role most targeted is that of antioxidant. Keywords: Vitamin E, antioxidants, therapy, oxidative stress


Author(s):  
Paulina Szczurek-Janicka ◽  
Katarzyna Ropka-Molik ◽  
Maria Oczkowicz ◽  
Sylwia Orczewska-Dudek ◽  
Mariusz Pietras ◽  
...  

2004 ◽  
Vol 171 (4S) ◽  
pp. 436-436 ◽  
Author(s):  
Hyung L. Kim ◽  
David B. Seligson ◽  
Nicolette Janzen ◽  
Matthew H. Bui ◽  
Robert A. Figlin ◽  
...  

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