A Genetic Algorithm to Improve a Neural Network to Predict a Patient’s Response to Warfarin

1993 ◽  
Vol 32 (01) ◽  
pp. 55-58 ◽  
Author(s):  
M. N. Narayanan ◽  
S. B. Lucas
Keyword(s):  
Neural Network ◽  
Genetic Algorithm ◽  
Neural Networks ◽  
Predictive Ability ◽  
Predictor Variables ◽  
Optimal Subset ◽  
The Neural Network ◽  
International Normalised Ratio ◽  
The Mean ◽  
Paired T Test

Abstract:The ability of neural networks to predict the international normalised ratio (INR) for patients treated with Warfarin was investigated. Neural networks were obtained by using all the predictor variables in the neural network, or by using a genetic algorithm to select an optimal subset of predictor variables in a neural network. The use of a genetic algorithm gave a marked and significant improvement in the prediction of the INR in two of the three cases investigated. The mean error in these cases, typically, reduced from 1.02 ± 0.29 to 0.28 ± 0.25 (paired t-test, t = −4.71, p <0.001, n = 30). The use of a genetic algorithm with Warfarin data offers a significant enhancement of the predictive ability of a neural network with Warfarin data, identifies significant predictor variables, reduces the size of the neural network and thus the speed at which the reduced network can be trained, and reduces the sensitivity of a network to over-training.

Estimation of Site Amplification from Geotechnical Array Data Using Neural Networks

2021 ◽  
Author(s):  
Daniel Roten ◽  
Kim B. Olsen
Keyword(s):  
Neural Network ◽  
Neural Networks ◽  
Site Response ◽  
Site Amplification ◽  
Data Driven ◽  
Vertical Array ◽  
The Neural Network ◽  
Simplifying Assumptions ◽  
The Mean ◽  
Fully Connected

ABSTRACT We use deep learning to predict surface-to-borehole Fourier amplification functions (AFs) from discretized shear-wave velocity profiles. Specifically, we train a fully connected neural network and a convolutional neural network using mean AFs observed at ∼600 KiK-net vertical array sites. Compared with predictions based on theoretical SH 1D amplifications, the neural network (NN) results in up to 50% reduction of the mean squared log error between predictions and observations at sites not used for training. In the future, NNs may lead to a purely data-driven prediction of site response that is independent of proxies or simplifying assumptions.

scholarly journals NEAT Snake: a both evolutionary and neural network adaptation approach

2020 ◽  
Author(s):  
Alisson Steffens Henrique ◽  
Vinicius Almeida dos Santos ◽  
Rodrigo Lyra
Keyword(s):  
Neural Network ◽  
Genetic Algorithm ◽  
Neural Networks ◽  
Decision Making ◽  
Genetic Algorithms ◽  
Real Time ◽  
Relative Position ◽  
Network Adaptation ◽  
The Neural Network

There are several challenges when modeling artificial intelligencemethods for autonomous players on games (bots). NEAT is one ofthe models that, combining genetic algorithms and neural networks,seek to describe a bot behavior more intelligently. In NEAT, a neuralnetwork is used for decision making, taking relevant inputs fromthe environment and giving real-time decisions. In a more abstractway, a genetic algorithm is applied for the learning step of the neuralnetworks’ weights, layers, and parameters. This paper proposes theuse of relative position as the input of the neural network, basedon the hypothesis that the bot profit will be improved.

A Hybrid Approach to Missing Data

2010 ◽  
pp. 45-70
Author(s):  
Tshilidzi Marwala
Keyword(s):  
Neural Network ◽  
Genetic Algorithm ◽  
Neural Networks ◽  
Missing Data ◽  
Hybrid Approach ◽  
Principal Component ◽  
Missing Data Imputation ◽  
The Neural Network ◽  
Genetic Algorithm Approach ◽  
Successful Approach

The problem of missing data in databases has recently been dealt with through the use computational intelligence. The hybrid of auto-associative neural networks and genetic algorithms has proven to be a successful approach to missing data imputation. Similarly, two auto-associative neural networks are developed to be used in conjunction with genetic algorithm to estimate missing data, and these approaches are compared to a Bayesian auto-associative neural network and genetic algorithm approach. One technique combines three neural networks to form a hybrid auto-associative network, while the other merges principal component analysis and neural networks. The hybrid of the neural network and genetic algorithm approach proves to be the most accurate when estimating one missing value, while a hybrid of principal component and neural networks is more consistent and captures patterns in the data more efficiently.

scholarly journals Neural networks application to determine the types and magnitude of aberrations from the pattern of the point spread function out of the focal plane

2021 ◽  
Vol 2086 (1) ◽  
pp. 012148
Author(s):  
P A Khorin ◽  
A P Dzyuba ◽  
P G Serafimovich ◽  
S N Khonina
Keyword(s):  
Neural Network ◽  
Neural Networks ◽  
Convolutional Neural Networks ◽  
Point Spread Function ◽  
Focal Plane ◽  
Prediction Errors ◽  
Point Spread ◽  
The Neural Network ◽  
Spread Function ◽  
The Mean

Abstract Recognition of the types of aberrations corresponding to individual Zernike functions were carried out from the pattern of the intensity of the point spread function (PSF) outside the focal plane using convolutional neural networks. The PSF intensity patterns outside the focal plane are more informative in comparison with the focal plane even for small values/magnitudes of aberrations. The mean prediction errors of the neural network for each type of aberration were obtained for a set of 8 Zernike functions from a dataset of 2 thousand pictures of out-of-focal PSFs. As a result of training, for the considered types of aberrations, the obtained averaged absolute errors do not exceed 0.0053, which corresponds to an almost threefold decrease in the error in comparison with the same result for focal PSFs.

scholarly journals Development of the classifier based on a multilayer perceptron using genetic algorithm and cart decision tree

2021 ◽  
Vol 5 (9 (113)) ◽  
pp. 82-90
Author(s):  
Lyudmila Dobrovska ◽  
Olena Nosovets
Keyword(s):  
Neural Network ◽  
Genetic Algorithm ◽  
Neural Networks ◽  
Decision Tree ◽  
Decision Trees ◽  
Multilayer Perceptron ◽  
Data Sets ◽  
Biomedical Data ◽  
Simulation Accuracy ◽  
The Neural Network

The problem of developing universal classifiers of biomedical data, in particular those that characterize the presence of a large number of parameters, inaccuracies and uncertainty, is urgent. Many studies are aimed at developing methods for analyzing these data, among them there are methods based on a neural network (NN) in the form of a multilayer perceptron (MP) using GA. The question of the application of evolutionary algorithms (EA) for setting up and learning the neural network is considered. Theories of neural networks, genetic algorithms (GA) and decision trees intersect and penetrate each other, new developed neural networks and their applications constantly appear. An example of a problem that is solved using EA algorithms is considered. Its goal is to develop and research a classifier for the diagnosis of breast cancer, obtained by combining the capabilities of the multilayer perceptron using the genetic algorithm (GA) and the CART decision tree. The possibility of improving the classifiers of biomedical data in the form of NN based on GA by applying the process of appropriate preparation of biomedical data using the CART decision tree has been established. The obtained results of the study indicate that these classifiers show the highest efficiency on the set of learning and with the minimum reduction of Decision Trees; increasing the number of contractions usually degrades the simulation result. On two datasets on the test set, the simulation accuracy was »83–87 %. The experiments carried out have confirmed the effectiveness of the proposed method for the synthesis of neural networks and make it possible to recommend it for practical use in processing data sets for further diagnostics, prediction, or pattern recognition

SCORING MODELING BASED ON NEURAL NETWORKS FOR DETERMINING A BANK BORROWER'S RATING

2020 ◽  
Vol 2020 (10) ◽  
pp. 54-62
Author(s):  
Oleksii VASYLIEV ◽  
Keyword(s):  
Neural Network ◽  
Neural Networks ◽  
Network Architecture ◽  
Statistical Data ◽  
Activation Function ◽  
Decision Making Process ◽  
Neural Network Architecture ◽  
Acceptable Accuracy ◽  
The Neural Network ◽  
Sigmoid Activation Function

The problem of applying neural networks to calculate ratings used in banking in the decision-making process on granting or not granting loans to borrowers is considered. The task is to determine the rating function of the borrower based on a set of statistical data on the effectiveness of loans provided by the bank. When constructing a regression model to calculate the rating function, it is necessary to know its general form. If so, the task is to calculate the parameters that are included in the expression for the rating function. In contrast to this approach, in the case of using neural networks, there is no need to specify the general form for the rating function. Instead, certain neural network architecture is chosen and parameters are calculated for it on the basis of statistical data. Importantly, the same neural network architecture can be used to process different sets of statistical data. The disadvantages of using neural networks include the need to calculate a large number of parameters. There is also no universal algorithm that would determine the optimal neural network architecture. As an example of the use of neural networks to determine the borrower's rating, a model system is considered, in which the borrower's rating is determined by a known non-analytical rating function. A neural network with two inner layers, which contain, respectively, three and two neurons and have a sigmoid activation function, is used for modeling. It is shown that the use of the neural network allows restoring the borrower's rating function with quite acceptable accuracy.

scholarly journals Optimizing the hardness of SLA printed objects by using the neural network and genetic algorithm

2019 ◽  
Vol 38 ◽  
pp. 117-124
Author(s):  
Guang Hu ◽  
Zhi Cao ◽  
Michael Hopkins ◽  
Conor Hayes ◽  
Mark Daly ◽  
...  
Keyword(s):  
Neural Network ◽  
Genetic Algorithm ◽  
The Neural Network

scholarly journals Discretization and machine learning approximation of BSDEs with a constraint on the Gains-process

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Idris Kharroubi ◽  
Thomas Lim ◽  
Xavier Warin
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Neural Networks ◽  
Differential Equations ◽  
Numerical Experiments ◽  
Optimization Problem ◽  
Learning Approach ◽  
The Neural Network ◽  
Machine Learning Approach ◽  
Mesh Grid

AbstractWe study the approximation of backward stochastic differential equations (BSDEs for short) with a constraint on the gains process. We first discretize the constraint by applying a so-called facelift operator at times of a grid. We show that this discretely constrained BSDE converges to the continuously constrained one as the mesh grid converges to zero. We then focus on the approximation of the discretely constrained BSDE. For that we adopt a machine learning approach. We show that the facelift can be approximated by an optimization problem over a class of neural networks under constraints on the neural network and its derivative. We then derive an algorithm converging to the discretely constrained BSDE as the number of neurons goes to infinity. We end by numerical experiments.

scholarly journals A novel approach for nitrogen diagnosis of wheat canopies digital images by mobile phones based on histogram

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xin Qi ◽  
Yanan Zhao ◽  
Yufang Huang ◽  
Yang Wang ◽  
Wei Qin ◽  
...  
Keyword(s):  
Neural Network ◽  
Mobile Phones ◽  
Mean Value ◽  
Wheat Cultivars ◽  
N Content ◽  
Color Parameters ◽  
The Neural Network ◽  
The Mean ◽  
Leaf N Content ◽  
Leaf N

AbstractThe accurate and nondestructive assessment of leaf nitrogen (N) is very important for N management in winter wheat fields. Mobile phones are now being used as an additional N diagnostic tool. To overcome the drawbacks of traditional digital camera diagnostic methods, a histogram-based method was proposed and compared with the traditional methods. Here, the field N level of six different wheat cultivars was assessed to obtain canopy images, leaf N content, and yield. The stability and accuracy of the index histogram and index mean value of the canopy images in different wheat cultivars were compared based on their correlation with leaf N and yield, following which the best diagnosis and prediction model was selected using the neural network model. The results showed that N application significantly affected the leaf N content and yield of wheat, as well as the hue of the canopy images and plant coverage. Compared with the mean value of the canopy image color parameters, the histogram could reflect both the crop coverage and the overall color information. The histogram thus had a high linear correlation with leaf N content and yield and a relatively stable correlation across different growth stages. Peak b of the histogram changed with the increase in leaf N content during the reviving stage of wheat. The histogram of the canopy image color parameters had a good correlation with leaf N content and yield. Through the neural network training and estimation model, the root mean square error (RMSE) and the mean absolute percentage error (MAPE) of the estimated and measured values of leaf N content and yield were smaller for the index histogram (0.465, 9.65%, and 465.12, 5.5% respectively) than the index mean value of the canopy images (0.526, 12.53% and 593.52, 7.83% respectively), suggesting a good fit for the index histogram image color and robustness in estimating N content and yield. Hence, the use of the histogram model with a smartphone has great potential application in N diagnosis and prediction for wheat and other cereal crops.

Application of neural networks in predictions of brake wear particulate matter emission

2021 ◽  
pp. 095440702110363
Author(s):  
Saša Vasiljević ◽  
Jasna Glišović ◽  
Nadica Stojanović ◽  
Ivan Grujić
Keyword(s):  
Neural Network ◽  
Neural Networks ◽  
Particulate Matter ◽  
Traffic Control ◽  
World Health ◽  
Vehicle Speed ◽  
System Pressure ◽  
The Neural Network ◽  
Vehicle Systems ◽  
Brake Wear

According to the World Health Organization, air pollution with PM10 and PM2.5 (PM-particulate matter) is a significant problem that can have serious consequences for human health. Vehicles, as one of the main sources of PM10 and PM2.5 emissions, pollute the air and the environment both by creating particles by burning fuel in the engine, and by wearing of various elements in some vehicle systems. In this paper, the authors conducted the prediction of the formation of PM10 and PM2.5 particles generated by the wear of the braking system using a neural network (Artificial Neural Networks (ANN)). In this case, the neural network model was created based on the generated particles that were measured experimentally, while the validity of the created neural network was checked by means of a comparative analysis of the experimentally measured amount of particles and the prediction results. The experimental results were obtained by testing on an inertial braking dynamometer, where braking was performed in several modes, that is under different braking parameters (simulated vehicle speed, brake system pressure, temperature, braking time, braking torque). During braking, the concentration of PM10 and PM2.5 particles was measured simultaneously. The total of 196 measurements were performed and these data were used for training, validation, and verification of the neural network. When it comes to simulation, a comparison of two types of neural networks was performed with one output and with two outputs. For each type, network training was conducted using three different algorithms of backpropagation methods. For each neural network, a comparison of the obtained experimental and simulation results was performed. More accurate prediction results were obtained by the single-output neural network for both particulate sizes, while the smallest error was found in the case of a trained neural network using the Levenberg-Marquardt backward propagation algorithm. The aim of creating such a prediction model is to prove that by using neural networks it is possible to predict the emission of particles generated by brake wear, which can be further used for modern traffic systems such as traffic control. In addition, this wear algorithm could be applied on other vehicle systems, such as a clutch or tires.

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