Platelet Distribution and Survival in Plasma Clots and Thrombi

1961 ◽  
Vol 06 (03) ◽  
pp. 470-484 ◽  
Author(s):  
Peter Wolf

SummaryViscous metamorphosis of platelets in native and sequestrene plasma, before and after thrombin and plasmin action, has been studied. A method for the examination of platelet distribution in plasma clots and tissue paraffin sections is described.It was found that not all platelets undergo viscous metamorphosis in plasma clots or in intravascular thrombi. Platelets before and after viscous metamorphosis are not digested by plasmin. After plasmin action intact platelets can still undergo viscous metamorphosis and the fibrils which are then produced are not made of fibrin.Thrombin in the absence of calcium ions will not cause platelets to undergo viscous metamorphosis.Total blockage of cardiac blood vessels by platelet masses in cases of cardiac infarction is demonstrated. The significance of these findings in relation to blood sludging, and future lines of treatment are discussed.

Author(s):  
Packiam Saranya ◽  
S. T. Ramesh ◽  
R. Gandhimathi

Abstract Alginates are quite abundant in nature as they occur both as a structural component in marine brown algae (Phaeophyceae) comprising up to 40% of dry matter and as capsular polysaccharides in soil bacteria. Alginic acid is the only polysaccharide, which naturally contains carboxyl groups in each constituent residue, and possesses various abilities for functional materials. Experiments were carried out for the water of turbidity 300 NTU. Alginate as such doesn't act as a coagulant instead it should be converted to calcium alginate by adding calcium ions. Calcium chloride was used for imparting calcium ions necessary for the reaction. The dosage of calcium was fixed as 50 mg/L, 75 mg/L, 100 mg/L, 150 mg/L, 200 mg/L, and alginate doses between 2 to 10 mg/L. Calcium dosage below 50 mg/L was not sufficient enough for the formation of egg-box structure which is responsible for the coagulation and flocculation process. For the mechanism of charge neutralization to take place effectively, calcium should be added first followed by alginate. pH and conductivity of the sample remain constant before and after the treatment. The dosage of alginate required for the treatment is less so the cost of treatment also will be very less, thus alginate can replace the usage of chemical coagulants like alum.


1979 ◽  
Vol 17 (6) ◽  
pp. 22-24

Nifedipine (Adalat - Bayer) is a recently introduced anti-anginal drug which reduces availability of calcium ions to heart muscle and dilates blood vessels, especially arteries. This combination of properties is new and potentially useful.


2021 ◽  
Vol 31 (6) ◽  
pp. 2850-2855
Author(s):  
Weiting An ◽  
Jindong Han

Retinal vein occlusion (RVO) is a retinal vascular disease that severely impairs the visual function of patients. Observing the changes of retinal blood vessels before and after treatment is of great significance for the prognostic evaluation of RVO. The rapid development and widespread use of fundus imaging technique, especially ultra-wide-angle fundus fluorescein angiography (UWFFA) and optical coherence tomography angiography (OCTA) have made our observation of the retinal blood vessels of RVO more comprehensive and meticulous. In this paper, we reviewed the latest research progress of UWFFA and OCTA in RVO.


1987 ◽  
Vol 115 (3) ◽  
pp. 489-495 ◽  
Author(s):  
A. Widmark ◽  
J. E. Damber ◽  
A. Bergh

ABSTRACT The effect of oestradiol-17β on testicular micro-circulation in intact and hypophysectomized rats was studied before and after treatment with human chorionic gonadotrophin (hCG). Treatment of intact rats with oestradiol-17β for 5 days did not influence vasomotion but decreased testicular interstitial fluid volume (IFV). Treatment of intact rats with 50 IU hCG 8 h before the experiment began induced an increase in testicular IFV, abolished vasomotion and increased the accumulation of polymorphonuclear leucocytes in the testicular venules and interstitium. These changes were unaffected by pretreatment with oestradiol-17β, despite the decreased testosterone production. However, pretreatment with oestradiol-17β potentiated the hCG-induced migration of polymorphonuclear leucocytes to the interstitium. The interstitial fluid volume and number of polymor phonuclear leucocytes in blood vessels were decreased in hypophysectomized rats, and vasomotion was abolished. Daily treatment with 5 IU hCG increased the IFV and the number of polymorphonuclear leucocytes in blood vessels, and preserved vasomotion. Treatment of hypophysectomized rats with oestradiol-17β decreased testosterone production but did not influence basal IFV, vasomotion or the changes in IFV and vasomotion induced by 5 IU hCG. The present study shows that the regulation of testicular vascular permeability and vasomotion may not be directly related to testicular steroidogenesis, and that oestrogens are probably not involved as a mediator of the hCG-induced changes in testicular microcirculation. J. Endocr. (1987) 115, 489–495


Author(s):  
Indra Yulianti

Hospitalization is a new experience that can make the child be afraid, it can take effect for his physical and psychology because of a new environment and the officer. Afraid feels and uncertain feeling is a danger warning that can make the children take an action for the threat. As a result the child is not cooperative. Then the nurse can give the child distraction therapy with playing therapy. Playing therapy is to change the children problematic are playing with a situation. This research is to prove the influence of therapy playing cut and stick paper on an anxiety in preschool children hospitalization in Blambangan Room, RSUD Prof. Dr. Soekandar. The population is all of the preschool children, with design pre-experiment with one group pretest-posttest approach. The Sample 15 children are taken with consecutive sampling. 15 child is given playing therapy playing cut and stick paper. Collection of data taking with Spence Children’s Anxiety Scale. Then data is processed and tested by modus analysis.  The anxiety score of the child before is given playing therapy is 9 (60%) normal anxiety, 5 (33,3%) slight anxiety, 1 (6,7%) medium anxiety. The anxiety score of the child after given playing therapy is 15 (100%) decreased anxiety. There was a change from before and after therapy to play cutting and sticking paper. Decreased anxiety from this stressors is delivered on the hypothalamus that will stimulate the adrenal glands to perform vasodilatation of blood vessels so that blood pressure decreases.


2015 ◽  
Vol 11 (4) ◽  
pp. 37-46
Author(s):  
И. Золотницкий ◽  
I. Zolotnitskiy ◽  
И. Лебеденко ◽  
I. Lebedenko

<p>We carried out the complex clinical-instrumential survey of hard tooth tissues, dentures, tissues and organes of oral cavity of young and middle working aged patients-musicians, who play copper wind instruments. We estimated adaptational-compensational abilities of tissues and organes of oral cavity of young and middle working aged patients-musicians, who play copper wind instruments, according to blood filling of regional blood vessels and reaction of supporting apparatus of parodontium, speed of salivation before and after stimulation by playing on musical instrument. In the result of the survey of patients we formed hypothetical morpho-functional stomatological portrait (status) of musician, who play copper wind instruments.</p>


1960 ◽  
Vol s3-101 (54) ◽  
pp. 207-221
Author(s):  
G. B. DAVID ◽  
K. B. MALLION ◽  
A. W. BROWN

1. It was accidentally found that methods of silvering synaptic end-feet sometimes blackened Golgi's ‘internal reticular apparatus’ in neurones of the central nervous system of the cat. 2. A method of achieving this consistently was worked out: (a) paraffin sections are coated with a collodion membrane; (b) the collodion membrane is soaked in silver nitrate; (c) the silver nitrate is reduced to metallic silver with a buffered formaldehyde solution; (d) steps (b) and (c) are repeated until the sections appear quite black; (e) the silver attached to structures other than the Golgi apparatus is removed with a ferricyanide/thiosulphate bleach; (f) the section is ‘toned’ with gold chloride, fixed in thiosulphate, and washed thoroughly; (g) the section is dehydrated, cleared, and finally mounted in Canada balsam, DPX, or similar media. Results: Golgi-apparatus, black; connective-tissue fibres, black; axons, grey to black; everything else is light grey or colourless. 3. A tentative hypothesis is advanced to explain the results obtained. 4. The following advantages are claimed for the new method: the cytoplasmic reticulum thus blackened resembles that seen in living neurones with the interference microscope; special methods of fixation are not required; the cytoplasmic reticulum of given cells can be studied before and after silvering; and serial sections of the same piece of tissue can be used for histochemical purposes.


2007 ◽  
Vol 352 ◽  
pp. 305-309
Author(s):  
Kyosuke Ueda ◽  
Takayuki Narushima ◽  
Tomoyuki Katsube ◽  
Hiroshi Kawamura ◽  
Takashi Goto

Calcium phosphate coating films were fabricated on mirror-polished or blast-treated titanium substrates using radio-frequency (RF) magnetron sputtering and they were evaluated in vitro. Immersion tests for the films were conducted using phosphate-buffered saline (PBS(-)), and apatite formation and the elution of calcium ions from the films were investigated. The bonding strengths between the calcium phosphate films and titanium substrates before and after the immersion tests were evaluated. After the immersion tests, a decrease in the bonding strength was observed for the coating films on the mirror-polished titanium substrates, while that for the blast-treated titanium substrates was almost the same as that before the immersion tests.


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