scholarly journals Axillary silicone lymphadenopathy secondary to augmentation mammaplasty

2010 ◽  
Vol 43 (02) ◽  
pp. 206-209
Author(s):  
Dimitrios M. Dragoumis ◽  
Anthoula S. Assimaki ◽  
Triantafyllos I. Vrizas ◽  
Aris P. Tsiftsoglou

ABSTRACTWe report a case involving a 45-year-old woman, who presented with an axillary mass 10 years after bilateral cosmetic augmentation mammaplasty. A lump was detected in the left axilla, and subsequent mammography and magnetic resonance imaging demonstrated intracapsular rupture of the left breast prosthesis. An excisional biopsy of the left axillary lesion and replacement of the ruptured implant was performed. Histological analysis showed that the axillary lump was lymph nodes containing large amounts of silicone. Silicone lymphadenopathy is an obscure complication of procedures involving the use of silicone. It is thought to occur following the transit of silicone droplets from breast implants to lymph nodes by macrophages and should always be considered as a differential diagnosis in patients in whom silicone prostheses are present.

Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
Luana Grazielle dos Santos Ferreira ◽  
Lilian de Sá Paz Ramos

Introduction: Adenomyoepithelioma of the breast is a rare, malignant, biphasic tumor of low grade, usually found in older women. Cases of metastasis are unusual, and when they occur, the most common sites are the lungs, brain, and thyroid. Clinical case: We discussed the case of a 49-year-old female patient with mammography and breast ultrasound showing a solid lesion, with ill-defined margins in the left breast. Excisional biopsy was performed, and the histological analysis confirmed the diagnosis of malignant adenomyoepithelioma with focally involved surgical margins. The treatment chosen was mastectomy with immediate reconstruction. Conclusion: The course and prognosis of the disease are unclear. Local recurrence is common; however, complete excision with safety margins represent the most effective form of treatment.


Author(s):  
Ilona Kulmala ◽  
John D. Boice ◽  
Joseph K. McLaughlin ◽  
Lisbet R. Holmich ◽  
Matti Pakkanen ◽  
...  

2020 ◽  
Vol 133 (5) ◽  
pp. 1355-1359
Author(s):  
Maria Peris-Celda ◽  
Laura Salgado-Lopez ◽  
Carrie Y. Inwards ◽  
Aditya Raghunathan ◽  
Carrie M. Carr ◽  
...  

Benign notochordal cell tumors (BNCTs) are considered to be benign intraosseous lesions of notochord origin; however, recent spine studies have suggested the possibility that some chordomas arise from BNCTs. Here, the authors describe two cases demonstrating histological features of BNCT and concomitant chordoma involving the clivus, which, to the best of the authors’ knowledge, have not been previously documented at this anatomical site.An 18-year-old female presented with an incidentally discovered clival mass. Magnetic resonance imaging revealed a 2.8-cm nonenhancing lesion in the upper clivus that was T2 hyperintense and T1 hypointense. She underwent an uneventful endoscopic transsphenoidal resection. Histologically, the tumor demonstrated areas of classic chordoma and a distinct intraosseous BNCT component. The patient completed adjuvant radiation therapy. Follow-up showed no recurrence at 18 months.A 39-year-old male presented with an incidentally discovered 2.8-cm clival lesion. The nonenhancing mass was T2 hyperintense and T1 hypointense. Surgical removal of the lesion was performed through an endoscopic transsphenoidal approach. Histological analysis revealed areas of BNCT with typical features of chordoma. Follow-up did not demonstrate recurrence at 4 years.These cases document histologically concomitant BNCT and chordoma involving the clivus, suggesting that the BNCT component may be a precursor of chordoma.


Author(s):  
Yun-Chung Cheung ◽  
Shir-Hwa Ueng ◽  
Shu-Hang Ng ◽  
Wen-Lin Kuo

Background: Contrast-enhanced spectral mammogram (CESM) is a modern technique providing additional information to detect or diagnose the breast cancers. Introduction: We present a rare ACC of breast on CESM. Methods: A 49-year-old woman with surgicopathological proved ACC is reported with features on CESM, sonography and contrast-enhanced magnetic resonance imaging (CE-MRI). Results: Sonography revealed a 1.4 cm × 1.2 cm × 1 cm circumscribe round mass in the upper outer quadrant of the left breast that was diagnosed to fibroadenoma. The mammogram did not show any discernible mass, however the recombined subtracted images displayed a circumscribe mass with thin rim enhancement and enhanced internal patches that were resembling to CE-MRI. Finally, the mass was proved to ACC. Conclusion: CESM facilitates detection of an isodense cancer and provides the enhanced features for differential diagnosis. Resembling CE-MRI, CESM displayed rim enhancement and internal enhanced patches as diagnostic clues for this case of ACC.


1993 ◽  
Vol 41 (8) ◽  
pp. 1163-1169 ◽  
Author(s):  
G Ocklind ◽  
J Talts ◽  
R Fässler ◽  
A Mattsson ◽  
P Ekblom

The extracellular matrix (ECM) is essential in regulating many cell functions in non-lymphoid cells, and the ECM may also play a role in the function of the immune system. Tenascin is a hexameric glycoprotein of the ECM. In mouse, two major polypeptides of MW 210 KD and 260 KD are formed by differential splicing. Northern blot screening of various mouse tissues showed that the short 6 KB tenascin message was strongly expressed in the adult thymus, whereas very little or no tenascin mRNA could be detected in spleen. In addition, immunoblotting and histological analysis with monoclonal anti-tenascin antibodies revealed the presence of tenascin in lymph nodes and spleen. In thymus, only a short-splice variant of tenascin was detected by immunoblotting, which supported the Northern blot results. Immunohistology showed that the epithelial reticular stroma in both embryonic and adult mouse thymus expressed tenascin, as did the postnatal mesenchymal reticular stroma in lymph nodes and spleen. The distribution of tenascin in the thymus was more restricted than that of fibronectin and laminin.


2014 ◽  
Vol 23 (6) ◽  
pp. 345-353 ◽  
Author(s):  
Mala Shah ◽  
Neil Tanna ◽  
Laurie Margolies

2003 ◽  
Vol 127 (11) ◽  
pp. 1498-1500
Author(s):  
Melissa A. Pasquale-Styles ◽  
Clara Milikowski

Abstract We describe a rare case of apocrine adenoma of the breast in a 45-year-old man. The patient presented with a tender lump in his left breast that had been present for 6 months. A mammogram identified a 3-mm nodular density in the breast, which was described as a hypoechoic nodule on ultrasound. Microscopic examination of tissue from an excisional biopsy revealed a 3-mm group of benign glands with abundant granular, eosinophilic cytoplasm and apical luminal blebbing, consistent with an apocrine adenoma. After reviewing other reported apocrine adenomas in the literature, we determined that our case was the smallest detected apocrine adenoma to be reported to date.


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