Cherubism: Report of a Case

AbstractCherubism, also known as familial fibrous dysplasia of the jaws or familial multilocular cystic disease is a rare hereditary, developmental disorder. This condition affects the posterior region of the jaws bilaterally in children belonging to the age group of 2 to 5 years. Maximum growth is recorded till puberty after which the lesion regresses over a period of time. Cherubism classically manifests radiographically as bilateral, multilocular radiolucencies affecting the posterior mandible and maxilla. Therapeutic management varies from patient to patient and is directed mainly by esthetic and functional concerns. The present report highlights the clinical and radiographic features of nonfamilial cherubism in a 6-year-old girl.

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229 Sleep-wake behavior, meal timings and digital media duration of Indians during COVID-19 Lockdown

SLEEP ◽

10.1093/sleep/zsab072.228 ◽

2021 ◽

Vol 44 (Supplement_2) ◽

pp. A91-A92

Author(s):

Babita Pande ◽

Meenakshi Sinha ◽

Ramanjan Sinha

Keyword(s):

Digital Media ◽

Sleep Duration ◽

Sleep Onset ◽

Therapeutic Management ◽

Daily Routine ◽

Age Group ◽

Younger Age ◽

Gender And Age ◽

Delayed Sleep ◽

The Impact

Abstract Introduction Lockdown and stay home order has been imposed on people in many countries including India to prevent the community transmission of COVID-19 pandemic. However this social restriction led to disturbed daily routine and lifestyle behaviour that is needed to be attended for proper therapeutic management of overall health during such crisis. The impact of lockdown on the most apparent behavioral changes viz. sleep-wake behaviour, major meal timings, and digital screen duration of Indians were investigated. In addition the effects of gender and age were explored. Methods After seeking permission from Ethical Institution, an online questionnaire based survey was circulated within India in the first week of May, 2020 for which total 1511 male and female (age ≥18 years) subjects participated. The sleep-wake behavior observed were sleep-wake timings, sleep duration, mid sleep time (MST) as function of lockdown, and social (lockdown) jetlag (SJL = MST before lockdown-MST during lockdown). Results The sleep onset-wakeup and meal times were significantly delayed during lockdown, which was more pronounced in younger age group. The sleep duration increased, specifically in young individuals during lockdown. Females showed more delayed sleep onset-waking times and first meal timing with longer sleep duration during lockdown. Increased digital media duration was observed in all age groups, primarily in males. The younger age group and specifically female reported higher SJL and delayed MST. A positive association was obtained between sleep duration & first meal time, and SJL & major meal timings/screen duration, and a significant negative relationship of sleep duration and SJL with age. Conclusion The study shows delayed sleep-wake schedule, meal timings and increased digital media duration among Indians during COVID-19 lockdown compared to before lockdown. Also, gender and age emerged as important mediating factors for this alteration. The pandemic has given opportunity to sleep more and compensate for the sleep. In spite of that, the higher social jetlag in young age group and female showed the compromised sleep and maladaption with societal timing. These findings have applied implications in sleep health during longer social isolation conditions and for proper therapeutic management. Support (if any) No

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Bronchoscopic Management of Airway Obstruction in Pediatric Endobronchial Tuberculosis

Canadian Respiratory Journal ◽

10.1155/2006/278680 ◽

2006 ◽

Vol 13 (4) ◽

pp. 219-221 ◽

Cited By ~ 6

Author(s):

Jeff SW Wong ◽

Calvin SH Ng ◽

Tak Wai Lee ◽

Anthony PC Yim

Keyword(s):

Literature Review ◽

Airway Obstruction ◽

Present Report ◽

Balloon Dilation ◽

Age Group ◽

Pediatric Age ◽

Pediatric Age Group ◽

Endobronchial Tuberculosis ◽

Severe Airway Obstruction

The present report describes a case of severe airway obstruction caused by endobronchial tuberculosis in an 11-year-old girl who was successfully treated by bronchoscopic balloon dilation. This case illustrates the insidious presentation and the increasingly important role of bronchoscopic intervention in the management of endobronchial tuberculosis. In addition, a brief literature review of the condition in the pediatric age group is included.

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Osteosarcoma and fibrous dysplasia: Radiographic features and differential diagnosis: A case report

Journal of Oral and Maxillofacial Surgery ◽

10.1016/0278-2391(94)90199-6 ◽

1994 ◽

Vol 52 (10) ◽

pp. 1095

Author(s):

G.H. Sperber

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Fibrous Dysplasia ◽

Radiographic Features

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Fibrous dysplasia a report of two cases with emphasis on radiographic features

Clinical Cancer Investigation Journal ◽

10.4103/2278-0513.176233 ◽

2016 ◽

Vol 5 (2) ◽

pp. 184 ◽

Cited By ~ 1

Author(s):

Smit Singla ◽

Akhilesh Verma ◽

Anjali Shetty ◽

Raghavendra Kini

Keyword(s):

Fibrous Dysplasia ◽

Radiographic Features

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Disorders Caused by Disorganization of Skeletal Constituents

Bone Dysplasias ◽

10.1093/med/9780190626655.003.0019 ◽

2018 ◽

pp. 717-756

Author(s):

Jürgen W. Spranger ◽

Paula W. Brill ◽

Christine Hall ◽

Gen Nishimura ◽

Andrea Superti-Furga ◽

...

Keyword(s):

Fibrous Dysplasia ◽

Clinical Findings ◽

Differential Diagnoses ◽

Fibrodysplasia Ossificans Progressiva ◽

Radiographic Features ◽

Multiple Cartilaginous Exostoses ◽

Progressive Osseous Heteroplasia

This chapter discusses disorders caused by disorganization of skeletal constituents and includes discussion on fibrous dysplasia, cherubism, progressive osseous heteroplasia, multiple cartilaginous exostoses, osteoglophonic dysplasia, fibrodysplasia ossificans progressiva, enchondromatosis, metaphyseal chondromatosis with 2-hydroxyglutaric acidura, genochondromatosis, and metachondromatosis. Each discussion includes major radiographic features, major clinical findings, genetics, major differential diagnoses, and a bibliography.

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First Reported Case of a Brodie Abscess in the Hand

Plastic Surgery Case Studies ◽

10.1177/2513826x17751095 ◽

2017 ◽

Vol 3 ◽

pp. 2513826X1775109

Author(s):

Bon Lam ◽

Jill P. Stone ◽

Jennifer L. K. Matthews

Keyword(s):

Patient Outcome ◽

Present Report ◽

Radiographic Features ◽

Metacarpal Head ◽

Insidious Onset

Brodie abscess is an uncommon form of osteomyelitis. Diagnosis can be difficult due to the insidious onset of symptoms and radiographic features that closely resemble more common pathology. The present report describes a patient with a Brodie abscess of the metacarpal head. The presentation, workup, management, and patient outcome are described.

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Possible Evidence for a Fall in the Prevalence of High-Functioning Pervasive Developmental Disorder with Age?

Autism Research and Treatment ◽

10.1155/2011/325495 ◽

2011 ◽

Vol 2011 ◽

pp. 1-8 ◽

Cited By ~ 2

Author(s):

M. Balfe ◽

D. Tantam ◽

M. Campbell

Keyword(s):

Pervasive Developmental Disorder ◽

Developmental Disorder ◽

Community Sample ◽

Contributory Factor ◽

Age Group ◽

Willingness To Participate ◽

High Functioning ◽

Previous Diagnosis ◽

The City

A survey was undertaken to investigate the prevalence of high-functioning pervasive developmental disorder (HFPDD) in a community sample of teenagers and adults aged 13 and above in the city of Sheffield, UK. 112 possible and definite cases were found, of whom 65 (57%) had a previous diagnosis. The detected prevalence of possible or definite HFPDD was found to be 0.24 per 1000 of the population of Sheffield city aged 13 or over, but the prevalence by year of age fell from a maximum of 1.1 per 1000 in the group aged 13 to 14 years old (1 young adult in every 900 in this age group) to 0.03 per 1000 in the over 60s (1 person in every 38500 in this age group). The results of this study are preliminary and need follow-up investigation in larger studies. We suggest several explanations for the findings, including reduced willingness to participate in a study as people get older, increased ascertainment in younger people, and increased mortality. Another contributory factor might be that the prevalence of high-functioning pervasive development disorder may decline with age. This raises the possibility that AS symptoms might become subclinical in adulthood in a proportion of people with HFPDD.

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Canine leishmaniosis in Tunisia: Growing prevalence, larger zones of infection

PLoS Neglected Tropical Diseases ◽

10.1371/journal.pntd.0009990 ◽

2021 ◽

Vol 15 (12) ◽

pp. e0009990

Author(s):

Ali Bouattour ◽

Amine Amri ◽

Jaber Amine Belkhiria ◽

Adel Rhim ◽

Ons Fezaa ◽

...

Keyword(s):

Leishmania Infantum ◽

Environmental Changes ◽

Climatic Factors ◽

Arid Zone ◽

Present Report ◽

Clinical Signs ◽

Sand Fly ◽

Canine Leishmaniosis ◽

Age Group ◽

Bioclimatic Zone

Background Discovered by Nicolle and Comte in 1908 in Tunisia, Leishmania infantum is an intracellular protozoan responsible for zoonotic canine leishmaniosis (CanL) and zoonotic human visceral leishmaniasis (HVL). It is endemic in several regions of the world, including Tunisia, with dogs considered as the main domestic reservoir. The geographic expansion of canine leishmaniosis (CanL) has been linked to global environmental changes that have affected the density and the distribution of its sand fly vectors. Methodology/Principal findings In this study, a cross-sectional epidemiological survey on CanL was carried out in 8 localities in 8 bioclimatic areas of Tunisia. Blood samples were taken from 317 dogs after clinical examination. Collected sera were tested by indirect fluorescent antibody test (IFAT; 1:80) for the presence of anti-Leishmania infantum antibodies. The overall seroprevalence was 58.3% (185/317). Among positive dogs, only 16.7% showed clinical signs suggestive of leishmaniosis. Seroprevalence rates varied from 6.8% to 84.6% and from 28% to 66% by bioclimatic zone and age group, respectively. Serological positivity was not statistically associated with gender. The presence of Leishmania DNA in blood, using PCR, revealed 21.2% (64/302) prevalence in dogs, which varied by bioclimatic zone (7.3% to 31%) and age group (7% to 25%). The entomological survey carried out in the studied localities showed 16 species of the two genera (Phlebotomus and Sergentomyia). P. perniciosus, P. papatasi, and P. perfiliewi were the most dominant species with relative abundances of 34.7%, 25% and 20.4%, respectively. Conclusions/Significance The present report suggests a significant increase of CanL in all bioclimatic areas in Tunisia and confirms the ongoing spread of the infection of dogs to the country’s arid zone. Such an expansion of infection in dog population could be attributed to ecological, agronomic, social and climatic factors that affect the presence and density of the phlebotomine vectors.

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An analytical study on effect of constitutional homeopathic medicines for single arm disability patients in age group of 6-15 years

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl4.3773 ◽

2020 ◽

Vol 11 (SPL4) ◽

pp. 223-225

Author(s):

Satyanarayana P ◽

Rajesh P ◽

Ravi P ◽

Rajamuthiah N

Keyword(s):

Learning Disability ◽

Reading Skills ◽

Developmental Disorder ◽

Clinical Feature ◽

Age Group ◽

Writing Difficulties ◽

Physiological Processes ◽

Before And After ◽

Treatment Analysis ◽

Constitutional Medicine

Learning disability is a disorder of the basic physiological processes involved in using or understanding language written or spoken which manifest itself in imperfect ability to listen, speak, read, write, spell or do mathematical calculations. In this study, homeopathic medicine was prescribed to the 30 children having learning disability of age group 6 to 15. Synthesis repertory was used for repertorisation of cases and to find out constitutional medicine. Single dose of medicine was prescribed to every child at the interval of 10 to 15 days in required potency. Pre-assessment of each child was done with "Is It Dyslexia" free online evaluation by Davis Dyslexia Association. Visual Analogue Scale was used for before and after treatment analysis. Study showed significant result with mild to moderate improvement in 30 patients. Dyslexia and Dysgraphia come under category of specific developmental disorder. Dyslexia is characterized by failure to develop adequate reading skills and delay in learning to read which become apparent between the ages of 6 to 9 years. The clinical feature includes omission, distortions or substitutions of words, long hesitations, reversal of words or simply slow reading, writing difficulties are often coexisted with dyslexia. Clinical features include difficulties with spelling, syntax grammar and composition.

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