scholarly journals A Review on the Application of Silver Nanoparticles in Oral and Maxillofacial Surgery

Author(s):  
Diane Isabel Selvido ◽  
Bishwa Prakash Bhattarai ◽  
Apiwat Riddhabhaya ◽  
Kadkao Vongsawan ◽  
Siripen Arunpraphan ◽  
...  

AbstractSilver nanoparticles (AgNPs) have been taken advantage of in dentistry because of their good antibacterial resistance and self-sustaining potential. However, in oral and maxillofacial surgery and implantology, there is a lesser amount of evidence. The few pieces of evidence need to be accentuated for possible amplification of its use in the dental setting. AgNPs in oral and maxillofacial surgery can be used in wound healing, bone healing, extractions, guided tissue regeneration, apical surgeries, oral cancer, and dental implants. This review aims to feature the utilization and application of AgNPs in oral and maxillofacial surgery and implant dentistry, emphasizing its need for potential future development in clinical settings.

2019 ◽  
Vol 47 (3) ◽  
pp. 389-393 ◽  
Author(s):  
Fabian Matthias Eckstein ◽  
Valesca Pinsel ◽  
Matthias Christian Wurm ◽  
André Wilkerling ◽  
Eva-Maria Dietrich ◽  
...  

Author(s):  
Seied Omid Keyhan ◽  
Hamidreza Fallahi ◽  
Alireza Jahangirnia ◽  
Mohammad Taher Amirzade-Iranaq ◽  
Mohammad Hosein Amirzade-Iranaq

Author(s):  
Ievgen Fesenko

“Talent attracts talent” — Jay Elliot and William L. Simon Authors of textbook The Steve Jobs Way Whether you are from the field of periodontics, trying to develop new flap techniques around implants, prosthodontics, or oral and maxillofacial surgery, you can definitely see state of the art chapters by Dr. Todd R. Schoenbaum in Newman & Carranza’s Clinical Periodontology (13th edition, 2018) [1]. Todd R. Schoenbaum, DDS, FACD is a highly experienced Associate Clinical Professor at the famous University of California, Los Angeles (UCLA) moves extremely fast bringing implant dentistry to new high levels of aesthetics and function. And what happens when a star starts to shine brightly? He starts to attract other stars. The 25 authors who are representing 11 countries and 10 world class universities contributed to Implants in the Aesthetic Zone: A Guide for Treatment of the Partially Edentulous Patient. Textbook consists of sixteen Chapters, six of which, are precisely focused on the surgical aspects. In summary, it`s a great pleasure to recommend such masterpiece to everyone who is interested in improving their implant treatment with aesthetics, predictability, and function.


2021 ◽  
Vol 22 (23) ◽  
pp. 12623
Author(s):  
Hsin-Pei Weng ◽  
Yuan-Yang Cheng ◽  
Hsin-Lun Lee ◽  
Tai-Yi Hsu ◽  
Yu-Tang Chang ◽  
...  

As a source of growth factors for expediting wound healing and tissue regeneration, plasma-rich plasma (PRP) has been extensively applied in diverse fields including orthopaedics, ophthalmology, oral and maxillofacial surgery, dentistry, and gynaecology. However, the function of PRP in metabolic regulations remains enigmatic. A standardized method was devised herein to enrich growth factors and to lyophilize it as enhanced PRP (ePRP) powder, which could become ubiquitously available without mechanical centrifugation in clinical practice. To identify metabolic reprogramming in human dermal fibroblasts under ePRP treatment, putative metabolic targets were identified by transcriptome profiling and validated for their metabolic effects and mechanism. ePRP does not only promote wound healing but re-aligns energy metabolism by shifting to glycolysis through stimulation of glycolytic enzyme activity in fibroblasts. On the contrary, oxygen consumption rates and several mitochondrial respiration activities were attenuated in ePRP-treated fibroblasts. Furthermore, ePRP treatment drives the mitochondrial resetting by hindering the mitochondrial biogenesis-related genes and results in a dampened mitochondrial mass. Antioxidant production was further increased by ePRP treatment to prevent reactive oxygen species formation. Besides, ePRP also halts the senescence progression of fibroblasts by activating SIRT1 expression. Importantly, the glycolytic inhibitor 2-DG can completely reverse the ePRP-enhanced wound healing capacity, whereas the mitochondrial inhibitor oligomycin cannot. This is the first study to utilize PRP for comprehensively investigating its effects on the metabolic reprogramming of fibroblasts. These findings indicate that PRP’s primary metabolic regulation is to promote metabolic reprogramming toward glycolytic energy metabolism in fibroblasts, preserving redox equilibrium and allowing anabolic pathways necessary for the healing and anti-ageing process.


2007 ◽  
Vol 8 (1) ◽  
pp. 52-59 ◽  
Author(s):  
Wasiu Lanre Adeyemo ◽  
Akinola Ladipo Ladeinde ◽  
Mobolanle Olugbemiga Oguniewe

Abstract Aim Extraction healing complications have been attributed to several factors. The influence of trans-operative complications on an extraction site wound healing was the focus of this investigation. Methods and Materials This prospective study was conducted at the Oral Surgery Clinic of the Department of Oral and Maxillofacial Surgery of the Lagos University Teaching Hospital (LUTH) in Nigeria . Subjects selected were those referred for one or two adjacent extractions and who satisfied the inclusion criteria for the study. The relevant pre-operative information recorded for each patient were age and sex of patient, indications for extraction, time taken to extract the tooth, tooth/teeth removed, and any trans-operative complications. Extractions were performed with dental forceps, elevators, or both under local anaesthesia. Patients were blindly evaluated on the third and seventh post-operative day for socket healing assessment without reference to preoperative information on the patients. Results Seventy-three (24.25%) of 301 teeth considered for socket healing assessment had various transoperative complications due to accidental crown, root, or alveolar bone fractures. Of the 73 extractions with trans-operative complications during extraction, 18 developed a socket healing complication, while 17 of the 228 extractions without trans-operative complications developed socket healing complications (p = .000). The mean (SD) time taken to extract teeth developing healing complications was also found to be significantly longer than those without healing complications (p < .01). Conclusions The study demonstrated the combination of tooth/bone fragments in the socket and increased time of extraction due to trans-operative complications and accidents predispose to the development of extraction site wound healing disturbance. Citation Adeyemo WL, Ladeinde AL, Ogunlewe MO. Influence of Trans-operative Complications on Socket Healing Following Dental Extractions. J Contemp Dent Pract 2007 January;(8)1:052-059.


Author(s):  
Diane Isabel Selvido ◽  
Bishwa Prakash Bhattarai ◽  
Dinesh Rokaya ◽  
Nattisa Niyomtham ◽  
Natthamet Wongsirichat

AbstractOver the years, the pain has been defined numerous times in several ways. In oral and maxillofacial surgery, the occurrence of pain, especially postoperatively, is anticipated. Pain arises as a combination of various processes after tissue damage. Distinct pain experiences in oral surgery were depicted in several previous studies, adding knowledge to the field. The management of these encounters has been suggested over time, improving treatment approaches in the clinical setting. This review aims to understand the pain and its types and intervention in the field of oral and maxillofacial surgery.


Author(s):  
CHELSEA JEGADISH ◽  
JACOB RAJA ◽  
JOHNSON RAJA JAMES ◽  
MOHAN RAJ JP ◽  
DIVYA LAL.S

Piezoelectric surgery was first explained by French Jacques and Pierre Curie in 1880. Piezoelectric bone surgery is a novel osteotomy and osteoplasty technique invented by Professor Vercellotti in 1988 to overcome the limitations of traditional instrumentation in oral bone surgery by modifying and improving conventional ultrasound technology. The cutting action is the result of linear microvibrations, in amplitude between 30 and 200 μm that allow to obtain a micrometer precision in the range of 25-29 KHz modulated ultrasonic resonant frequency. Nerves, vessels, and soft tissue are preserved by the microvibrations (60 to 200 mm/sec), which are optimally adjusted to target only mineralized tissue. It is a minimally invasive osteotomy device to achieve unparallel precision, patient comfort, intra-operative sensitivity, intra-operative visibility, blood free surgical site and reduced damage to the surrounding soft tissues, osteocytes and important structures like nerves, muscles and mucosa. Also Piezosurgery is very useful in harvesting autogenous bone for regenerating periodontal defects. Various treatment modalities are based on removal of etiologic factors and preserving bone architecture. Recently this novel surgical approach has gained popularity in various fields of dental implantology, oral and maxillofacial surgery, endodontics, and orthopedics. This article aims to review the clinical calibre of piezosurgery in the field of periodontology and implant dentistry. Key Words : LESS INVASIVE, PRECISION CUTTING, MICRO VIBRATIONS, FASTER RECOVERY, PIEZO TECHNIQUE


Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 517
Author(s):  
Nurul Aida Ngah ◽  
Jithendra Ratnayake ◽  
Paul R. Cooper ◽  
George J. Dias ◽  
Darryl C. Tong ◽  
...  

Objective: The use of platelet concentrates (PCs) in oral and maxillofacial surgery, periodontology, and craniofacial surgery has been reported. While PCs provide a rich reservoir of autologous bioactive growth factors for tissue regeneration, their drawbacks include lack of utility for long-term application, low elastic modulus and strength, and limited storage capability. These issues restrict their broader application. This review focuses on the lyophilization of PCs (LPCs) and how this processing approach affects their biological and mechanical properties for application as a bioactive scaffold for craniofacial tissue regeneration. Materials and Methods: A comprehensive search of five electronic databases, including Medline, PubMed, EMBASE, Web of Science, and Scopus, was conducted from 1946 until 2019 using a combination of search terms relating to this topic. Results: Ten manuscripts were identified as being relevant. The use of LPCs was mostly studied in in vitro and in vivo craniofacial bone regeneration models. Notably, one clinical study reported the utility of LPCs for guided bone regeneration prior to dental implant placement. Conclusions: Lyophilization can enhance the inherent characteristics of PCs and extends shelf-life, enable their use in emergency surgery, and improve storage and transportation capabilities. In light of this, further preclinical studies and clinical trials are required, as LPCs offer a potential approach for clinical application in craniofacial tissue regeneration.


Author(s):  
Rahmi Syaflida Dalimunte ◽  
Olivia Avriyanti Hanafiah ◽  
Hendry Rusdy

Objective: This study aims to investigate the effects of black cumin extract (Nigella sativa) on the process of wound healing in tooth extraction sockets. Material and Methods: This study involved 24 patients from the Department of Oral and Maxillofacial Surgery grouped into the control and treatment groups. After extracting the first or second molar left or right in adult patients, the black cumin extractwas applied to the socket in the treatment group as soon as possible while it was not applied in the control group. The sockets were divided into 1,2,3 groups, which were treated as black cumin extracts of 10%, 12%, and 14% respectively. On day 1,3,7, patients were recalled and sockets size were calculated to analyze wound healing. Results: Black cumin was found to be able to make the wound healing faster in the treatment group when compared to the control group. Although the effect was not immediately apparent on the second day, on the seventh day the group treated with black cumin extract had a smaller sizing average compared to the control group. The concentration of 12% black cumin extract was found to have the best effect on wound healing. Significance of findings: Black cumin extract can make wound healing in tooth extraction sockets in patients.


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