Jugular Bulb Diverticula: Clinical and Radiologic Aspects

2003 ◽  
Vol 128 (3) ◽  
pp. 382-386 ◽  
Author(s):  
Cem Bilgen ◽  
Tayfun Kirazli ◽  
Fatih Ogut ◽  
Secil Totan
Keyword(s):  
High Resolution ◽  
Clinical Presentation ◽  
Clinical Symptoms ◽  
Jugular Bulb ◽  
Clinical Findings ◽  
The Other ◽  
Reference Line ◽  
Ct Scans ◽  
Number Of Patients ◽  
Axial Ct

OBJECTIVE: This study was performed to determine the clinical presentation of jugular diverticulum and its relevance with the extension of the lesion. STUDY DESIGN: The records and high-resolution CT scans of 1474 patients, with otologic symptoms or related clinical findings, were evaluated retrospectively. In 17 cases in which CT scans revealed the presence of jugular diverticulum, sensorineural symptoms were evaluated with respect to a reference line, perpendicular to the basal turn of the cochlea and tangent to the vestibule in axial CT scan images. RESULTS: When the extension of jugular diverticulum was posterior to the reference line, sensorineural symptoms with vertigo were dominant in most patients (72.7%) in this group. On the other hand, for the patients with anterior-extending jugular diverticulum, sensorineural symptoms without vertigo were detected in 50% of patients, whereas 33.3% had sensorineural symptoms with vertigo. CONCLUSION: This study revealed a relationship between the extension of jugular diverticulum and clinical symptoms. However, this relationship lacks statistical evidence because of the limited number of patients.

scholarly journals Different Clinical Presentation of Appendicolithiasis. The Report of Three Cases and Review of the Literature

2011 ◽  
Vol 4 ◽  
pp. CPath.S6757 ◽  
Author(s):  
Bulent Kaya ◽  
Cengiz Eris
Keyword(s):  
Computed Tomography ◽  
Clinical Presentation ◽  
Clinical Symptoms ◽  
Perforated Appendicitis ◽  
Clinical Findings ◽  
Complicated Appendicitis ◽  
The Other ◽  
Mineral Deposits ◽  
Review Of The Literature ◽  
Abdominal Computed Tomography

An appendicolith is composed of firm feces and some mineral deposits. After increased use of abdominal computed tomography, appendicoliths are more frequently detected. Most of the patients with appendicolith are asymptomatic. However, an appendicolith may be associated with complicated appendicitis with serious outcomes. We reported three patients who exhibited different clinical symptoms due to appendicolithiasis. While one of the patients was confused with urolithiasis, the other two patients presented with phlegmenous and perforated appendicitis. We submit that appendicoliths may present different clinical findings and can mimic several pathologies including urinary disorders.

Computer-Aided Diagnosis in Jaundice: Comparison of Knowledge-based and Probabilistic Approaches

1996 ◽  
Vol 35 (01) ◽  
pp. 41-51 ◽  
Author(s):  
F. Molino ◽  
D. Furia ◽  
F. Bar ◽  
S. Battista ◽  
N. Cappello ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Clinical Information ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Clinical Documentation ◽  
Data Set ◽  
Knowledge Based ◽  
Number Of Patients ◽  
Support Tools ◽  
Aided Diagnosis

AbstractThe study reported in this paper is aimed at evaluating the effectiveness of a knowledge-based expert system (ICTERUS) in diagnosing jaundiced patients, compared with a statistical system based on probabilistic concepts (TRIAL). The performances of both systems have been evaluated using the same set of data in the same number of patients. Both systems are spin-off products of the European project Euricterus, an EC-COMACBME Project designed to document the occurrence and diagnostic value of clinical findings in the clinical presentation of jaundice in Europe, and have been developed as decision-making tools for the identification of the cause of jaundice based only on clinical information and routine investigations. Two groups of jaundiced patients were studied, including 500 (retrospective sample) and 100 (prospective sample) subjects, respectively. All patients were independently submitted to both decision-support tools. The input of both systems was the data set agreed within the Euricterus Project. The performances of both systems were evaluated with respect to the reference diagnoses provided by experts on the basis of the full clinical documentation. Results indicate that both systems are clinically reliable, although the diagnostic prediction provided by the knowledge-based approach is slightly better.

scholarly journals Dermoscopy of topical steroid-dependent or damaged face: A cross-sectional study

2021 ◽  
Vol 0 ◽  
pp. 1-7
Author(s):  
Sheenam Sethi ◽  
Payal Chauhan ◽  
Rashmi Jindal ◽  
Yashwant Singh Bisht
Keyword(s):  
Clinical Symptoms ◽  
Low Cost ◽  
Topical Steroid ◽  
Cross Sectional Study ◽  
Clinical Findings ◽  
Cross Sectional ◽  
Female Ratio ◽  
Exact Test ◽  
Steroid Dependent ◽  
Number Of Patients

Background: Topical corticosteroid (TCS) abuse is rampant and results in steroid addiction labeled as topical steroid-dependent or damaged face (TSDF). Indian market is replete with triple combination creams containing TCS sold as over-the-counter products at low cost, luring people to use them without prescription. The resultant damage if detected late is irreversible and difficult to treat. Dermoscopy can help in the early identification of features of TSDF at a preclinical stage resulting in better prognosis. However, the literature on the same is limited. Aims: This study is undertaken to characterize dermoscopic features of TSDF and to correlate them with potency and duration of application of the TCS. Methods: One hundred and thirty-two patients aged 18 years or above, with clinical symptoms and signs suggestive of TSDF and with history of application of TCS on the face for a period of more than one month, were enrolled in the study. Their demographic details, clinical features, and dermoscopy findings were recorded using a predesigned structured format. Comparison of dermoscopic findings with clinical examination, gender, potency of TCS, and duration of TCS use was done using Chi-square test, Fisher’s exact test, and one-tailed Z-test. Results: Mean age of the patients was 31.7 ± 8.1 years. Male to female ratio was 2:9. Sixty-nine (52.3%) patients abused TCS for more than one year. Clinical findings noted in the patients were erythema (81.1%), hyperpigmentation (80.3%), and hypertrichosis (68.2%). The most common dermoscopy findings seen were brown globules (96.2%), red diffuse areas (92.4%), vessels (87.1%), white structureless areas (86.4%), and hypertrichosis (80.3%). Red diffuse areas, vessels, brown globules, white structureless areas, and white hair were observed in a statistically higher proportion of cases dermoscopically. Y-shaped vessels and brown globules were seen in significantly higher number of patients, using TCS for more than three months and in those continuing it beyond six months, polygonal vessels were predominant. Limitations: Lack of histopathological correlation is the limitation of our study. Furthermore, brown globules seen in 96.2% patients of TSDF on dermoscopy may have been over-estimated and not always signify TSDF; instead, it could represent melasma for which patient applied TCS. Conclusion: Dermoscopy in TSDF can help dermatologists in a multitude of ways from confirming the diagnosis to differentiating from other causes of red face and predicting the approximate duration of TCS abuse.

scholarly journals Report of the Phenotype of a Patient with Roberts Syndrome and a Rare ESCO2 Variant

2019 ◽  
Vol 09 (01) ◽  
pp. 058-062
Author(s):  
Carla Bastos da Costa Almeida ◽  
Amanda Thum Welter ◽  
Gabriel Dotta Abech ◽  
Gabriela Rangel Brandão ◽  
José Antônio Monteiro Flores ◽  
...  
Keyword(s):  
High Resolution ◽  
Molecular Analysis ◽  
Genetic Disease ◽  
Autosomal Recessive ◽  
Clinical Presentation ◽  
Clinical Findings ◽  
Roberts Syndrome ◽  
Brazilian Patient ◽  
Exon 4

AbstractRoberts syndrome is a rare autosomal recessive genetic disease. In this report, we report a Brazilian patient with a rare ESCO2 variant. The patient manifested a broad range of clinical findings including the significant, bilateral shortening of the extremities. He deteriorated and passed away at 20 days of age. High-resolution GTG-banded karyotype showed lack of centromeric constriction in some chromosomes, premature centromere separation in others, and repulsion of the heterochromatin regions. Molecular analysis of the ESCO2 gene revealed a deletion of 4 bp involving exon 4 in homozygosity (NM_00107420.2:c.875_878delACAG), which causes loss of ESCO2 function. We describe the clinical presentation caused by a rare ESCO2 variant.

scholarly journals SARS-CoV-2 in Pediatric Inpatient Care: Management, Clinical Presentation and Utilization of Healthcare Capacity

Healthcare ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1190
Author(s):  
Christine Busch ◽  
Maximilian Blickle ◽  
Beatrix Schmidt ◽  
Laura Katharina Sievers ◽  
Constanze Pfitzer
Keyword(s):  
Inpatient Care ◽  
Clinical Presentation ◽  
Hospital Admissions ◽  
Clinical Symptoms ◽  
Economic Consequences ◽  
Hospital Treatment ◽  
Clinical Center ◽  
Number Of Patients ◽  
Pediatric Inpatient ◽  
Utilization Of Healthcare

This study scrutinizes management and clinical presentation of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) in pediatric inpatient care and evaluates the utilization of pediatric healthcare capacity during the pandemic. Within this retrospective cohort study, we systematically reviewed data of all 16,785 pediatric patients (<18 years admitted to our clinical center between January 2018 and June 2021). Data on SARS-CoV-2 test numbers, hospital admissions and clinical characteristics of infected patients were collected. Since January 2020, a total of 2513 SARS-CoV-2 tests were performed. In total, 36 patients had a positive test result. In total, 25 out of 36 SARS-CoV-2 positive children showed at least mild clinical symptoms while 11 were asymptomatic. Most common clinical symptoms were fever (60%), cough (60%) and rhinitis (20%). In parallel with the rising slope of SARS-CoV-2 in spring and fall 2020, we observed a slight decrease in the number of patients admitted to the pediatric department while the median duration of hospital treatment and intensive care occupancy remained unchanged. This study underlines that SARS-CoV-2 infected children most frequently exhibit an asymptomatic or mild clinical course. Noteworthy, the number of hospital admissions went down during the pandemic. The health and economic consequences need to be discussed within health care society and politics.

Abstract 2491: Cerebral Amyloid Angiopathy without Hemorrhagic Stroke: MRI Findings Associated with Transient Focal Symptoms

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Jenelle A Jindal ◽  
Alison M Ayres ◽  
Mahmut E Gurol ◽  
Kristin Schwab ◽  
Jonathan Rosand ◽  
...  
Keyword(s):  
Cerebral Amyloid Angiopathy ◽  
Hemorrhagic Stroke ◽  
Clinical Presentation ◽  
Clinical Symptoms ◽  
Massachusetts General Hospital ◽  
The Other ◽  
Superficial Siderosis ◽  
Amyloid Angiopathy ◽  
Neurologic Symptoms ◽  
Cerebral Amyloid

Background: The clinical presentation of cerebral amyloid angiopathy (CAA) includes not only hemorrhagic stroke, but also diverse syndromes such as transient focal neurologic symptoms, progressive cognitive dysfunction, subacute confusion, and seizures. We performed a systematic analysis of the neuroimaging features of these presentations to help elucidate their underlying pathophysiologies. Methods: We performed a retrospective review of all patients seen at Massachusetts General Hospital from 2000-2011 with 1) diagnosis of probable/definite CAA by Boston criteria, 2) clinical presentation other than hemorrhagic stroke, and 3) available MR images (including T2*-weighted, diffusion-weighted, and FLAIR). Review of clinical data for 44 subjects meeting these criteria (performed blinded to neuroimaging) yielded 3 categories of presentation: transient focal motor, sensory, or language symptoms (n=15; mean±SD age 74.4±8.1), memory/cognitive impairment over months-years (n=15; age 71.2±10.7), and subacute headache, confusion, generalized seizure, or syncope (n=14; age 73.6±9.8). Images were analyzed without knowledge of clinical symptoms for hemorrhagic lesions, acute infarcts, and regional T2-hyperintensities. Results: Superficial siderosis in cortical sulci (Panel A) was present in 10 of 15 (67%) patients presenting with transient focal symptoms versus 7 of 29 (24%) in the other subgroups (p<0.01). Most locations of superficial siderosis corresponded with the localization of the patient’s transient symptoms. Conversely, a pattern of T2-hyperintensities extending to subcortical white matter and overlying cortex (Panel B) was present in 8 of 14 (57%) patients presenting with headache, confusion, or seizure/syncope versus 3 of 30 (10%) in the other subgroups (p<0.005). Conclusions: These results suggest that the underlying trigger for CAA-related transient focal neurologic symptoms may often be superficial siderosis. They also support an association between the alternative presentation of headache, confusion, or seizure/syncope and T2-hyperintensities suggestive of the inflammatory subtype of CAA.

Petrous Jugular Malposition (Diverticulum)

1993 ◽  
Vol 109 (5) ◽  
pp. 847-852 ◽  
Author(s):  
Dennis G. Pappas ◽  
Ronald A. Hoffman ◽  
Noel L. Cohen ◽  
Roy A. Holliday ◽  
Dennis. G. Pappas
Keyword(s):  
High Resolution ◽  
Literature Review ◽  
Clinical Symptoms ◽  
Jugular Bulb ◽  
Tympanic Cavity ◽  
Pathologic Process ◽  
High Resolution Ct ◽  
Anatomic Variant ◽  
The Relationship

Jugular bulb anatomy is variable. A “high-riding” bulb extending into the tympanic cavity is a well-described anomaly. Petrous jugular malposition (diverticulum) (PJMD), however, is rare. The relationship between PJMD and clinical symptoms is questionable because the differentiation between PJMD as an anatomic variant and pathologic process is unproved. A literature review reveals 14 previously documented cases. We report an additional four cases. Diagnostic and management dilemmas are discussed, with the importance of high-resolution CT Stressed.

A Critical Review of Subclinical Hypothyroidism in Ayurveda

2017 ◽  
Vol 1 (4) ◽  
Author(s):  
Vidyadhar Balikai ◽  
S. G. Chavan ◽  
Prashanth A. S.
Keyword(s):  
Thyroid Gland ◽  
Thyroid Hormones ◽  
Subclinical Hypothyroidism ◽  
Clinical Presentation ◽  
Clinical Findings ◽  
Clinical Syndrome ◽  
The Other ◽  
Insidious Onset ◽  
Male To Female ◽  
Chronic Course

Subclinical Hypothyroidism is a clinical syndrome which result from the deficiency of Thyroid hormones. Usually, it runs a chronic course with slow and insidious onset. Sometimes it is only accidentally diagnosed. Thyroid gland abnormality where, on one hand influences body metabolism up to a great extent, on the other hand, it is found more in females with ratio of male to female being 1:6, if left untreated it can lead to severe complication. In Ayurveda there is no direct comparison regarding symptoms of Subclinical Hypothyroidism but on the basis of clinical presentation it can be correlated with different entities as syndrome, so it is difficult to give a single Ayurvedic term for it, as there are many systems which are involved in the pathogenesis of Subclinical Hypothyroidism. Hence the symptoms of Pre-clinical and post clinical findings are compared with Rasapradoshaja Vikaras.

Computer-Controlled Hrem Alignment Using Automated Diffractogram Analysis

1990 ◽  
Vol 48 (1) ◽  
pp. 532-533
Author(s):  
G.Y. Fan ◽  
O.L. Krivanek
Keyword(s):  
Electron Microscope ◽  
High Resolution ◽  
The Other ◽  
Full Information ◽  
Resolution Electron ◽  
Skilled Operator ◽  
Automatic Alignment ◽  
High Resolution Electron Microscope ◽  
Computer Controlled ◽  
Recorded Image

Full alignment of a high resolution electron microscope (HREM) requires five parameters to be optimized: the illumination angle (beam tilt) x and y, defocus, and astigmatism magnitude and orientation. Because neither voltage nor current centering lead to the correct illumination angle, all the adjustments must be done on the basis of observing contrast changes in a recorded image. The full alignment can be carried out by a computer which is connected to a suitable image pick-up device and is able to control the microscope, sometimes with greater precision and speed than even a skilled operator can achieve. Two approaches to computer-controlled (automatic) alignment have been investigated. The first is based on measuring the dependence of the overall contrast in the image of a thin amorphous specimen on the relevant parameters, the other on measuring the image shift. Here we report on our progress in developing a new method, which makes use of the full information contained in a computed diffractogram.

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